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The map label for this gene is sigW [H]

Identifier: 222527425

GI number: 222527425

Start: 5223339

End: 5223965

Strand: Reverse

Name: sigW [H]

Synonym: Chy400_4216

Alternate gene names: 222527425

Gene position: 5223965-5223339 (Counterclockwise)

Preceding gene: 222527426

Following gene: 222527424

Centisome position: 99.15

GC content: 55.98

Gene sequence:

>627_bases
GTGTCGGGACTATCCATTGATCTGTCGCTGTACGATGATGAAGAGGCACTGCTGGCCGGTTTGCGGCGCGGTGACCCTGA
TGCCTGTACGTGTTTTGTAAAACGTTTTGCCCCGCTTGTGTATGCCCGCGCACTCAACCTGGTAGGTGATGCTGACGAAG
CTGAGAATGTGTTGCAGACGACCTTCATCAAGGCGTGTGCAGCGTTACCGGAATATACCGGTGCAGGCAGTCTACGAAGC
TGGCTCTACCGGATTGCATCGAATGAGGGATTGATGCTGCTGCGGCAGAAGCGGGCGCAGCTTGACCTTGACGAAATAGG
TGATCTCAGCAGCGAAACCTCACTCTCGCAATTGGCACCACGCTGGGCTGTTGATCCGGCCAGGACTGTACTCGATGAGG
AATTACGGCGCGAAATTATGCAGGCAATCACCACATTACCCGATGCATTGCGGGTCGTGATAGTCTTGCGCGATATTGAG
CATTTGAGTACTGAAGAGACGGCCAGACAACTGGGCATCAGTCCGGCAGCGGTGAAGGTGCGTCTGCATCGTGCCCGCTT
GCGCCTGCGCGAACTGCTGGCTCGCTATGTCGAAGCGGTGGAGGAGCAGCGTGATGTTGACCAGTGA

Upstream 100 bases:

>100_bases
AACAGATTGCTGTGAAACGGGTTTAGCTGATCAAAGCACAGAGAGCTGTCCAGCGCAGACATGCTATACTGGAAAAAGTA
GCTGTGCTGGAGGAATTGCT

Downstream 100 bases:

>100_bases
CCATCATTCCTGTCATGAACTCATCGATCTTCTGAACGATTATCTCGATGGTGAATTGAGTGCGACTGAATGTAGTGAGT
TGGAAGAGCAACTTCGTCGT

Product: ECF subfamily RNA polymerase sigma-24 subunit

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSGLSIDLSLYDDEEALLAGLRRGDPDACTCFVKRFAPLVYARALNLVGDADEAENVLQTTFIKACAALPEYTGAGSLRS
WLYRIASNEGLMLLRQKRAQLDLDEIGDLSSETSLSQLAPRWAVDPARTVLDEELRREIMQAITTLPDALRVVIVLRDIE
HLSTEETARQLGISPAAVKVRLHRARLRLRELLARYVEAVEEQRDVDQ

Sequences:

>Translated_208_residues
MSGLSIDLSLYDDEEALLAGLRRGDPDACTCFVKRFAPLVYARALNLVGDADEAENVLQTTFIKACAALPEYTGAGSLRS
WLYRIASNEGLMLLRQKRAQLDLDEIGDLSSETSLSQLAPRWAVDPARTVLDEELRREIMQAITTLPDALRVVIVLRDIE
HLSTEETARQLGISPAAVKVRLHRARLRLRELLARYVEAVEEQRDVDQ
>Mature_207_residues
SGLSIDLSLYDDEEALLAGLRRGDPDACTCFVKRFAPLVYARALNLVGDADEAENVLQTTFIKACAALPEYTGAGSLRSW
LYRIASNEGLMLLRQKRAQLDLDEIGDLSSETSLSQLAPRWAVDPARTVLDEELRREIMQAITTLPDALRVVIVLRDIEH
LSTEETARQLGISPAAVKVRLHRARLRLRELLARYVEAVEEQRDVDQ

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=178, Percent_Identity=30.8988764044944, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 23274; Mature: 23143

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLSIDLSLYDDEEALLAGLRRGDPDACTCFVKRFAPLVYARALNLVGDADEAENVLQT
CCCCEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TFIKACAALPEYTGAGSLRSWLYRIASNEGLMLLRQKRAQLDLDEIGDLSSETSLSQLAP
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCCCCHHHHHHCC
RWAVDPARTVLDEELRREIMQAITTLPDALRVVIVLRDIEHLSTEETARQLGISPAAVKV
CCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RLHRARLRLRELLARYVEAVEEQRDVDQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGLSIDLSLYDDEEALLAGLRRGDPDACTCFVKRFAPLVYARALNLVGDADEAENVLQT
CCCEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TFIKACAALPEYTGAGSLRSWLYRIASNEGLMLLRQKRAQLDLDEIGDLSSETSLSQLAP
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCCCCHHHHHHCC
RWAVDPARTVLDEELRREIMQAITTLPDALRVVIVLRDIEHLSTEETARQLGISPAAVKV
CCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RLHRARLRLRELLARYVEAVEEQRDVDQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]