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The map label for this gene is baeS [H]

Identifier: 222527374

GI number: 222527374

Start: 5155398

End: 5156756

Strand: Direct

Name: baeS [H]

Synonym: Chy400_4164

Alternate gene names: 222527374

Gene position: 5155398-5156756 (Clockwise)

Preceding gene: 222527373

Following gene: 222527375

Centisome position: 97.84

GC content: 57.03

Gene sequence:

>1359_bases
ATGCTTCGTTCGCTTACGACTCGCCTCATTCTGGCCTTTGCCCTGACCAGTCTGGTCGGTATTGGACTGGCGGCACTCCT
GGTTCGCCAGTTTGTGACCAACGAATTTGACACGTTTCTACTGGAGCAACAACGCAATGAATTGTTGGCGCAATTGATCA
CCGCATACCAGGAAACCGGTGATTGGAACGCAGCCACAGCAATCCTGAATGGACGATCAGACCGCGAGGGAGGCGATCCC
TTCGTGCCTATTGAAGTAGCCGATACAGAGGGGCGAATCGTTCTTTCTGACCGCCCGGCAGAGATCGGACGGAGCGTCGA
TCCAGAACTCCTGGCCCGTGGAACGCCTATCATGCTGAACGGCGAGCAAATCGGTACCCTACTGCCACTACCACCACCAC
GCCGGAATCCTGCTGAAGAGCGTTACCTGAGTCGGATTGATCTGGCACTTGGCGGAGCAGCATTTGGGGCGCTCGGTATT
GCGATAGTGTTAGGCTTTCTCCTGGCACAGGTGATCACGCGACCACTACGTGAACTCATGCAGGGGGTACGAGCCATCGC
CACTGGCGATCTGAGTCGGCGGGTACCGGTACGGTCGCGTGATGAACTAGGTGCACTGGCGCATCAATTCAACACCATGA
GTGCTGAGCTGCAACGCGCTACCGAACTACGCCGCCGCATGACAGCCGATATTGCCCATGATTTACGCACCCCGCTCACG
GTGATTGCCGGTTATCTGGAAGCCTTACGTGACGCCGAATTACCGGCAACACCGGCACGATTTGCGGCAATGCACACCGA
AACGCAAACGCTTTTGCGTCTCGTCGAAGACCTGCACACCCTCTCGCTGGCCGATGCAGGTGAGCTTCCCCTCCGCTGTC
GCGAAATTGCGGTTGATGATCTGCTAGAACGGATCGTGAGAATCTACAACGATGCCGCCCAACAGGCAGGAATCAGGCTC
CACCGGCAGAGTGAGCCGGCAGGTATGCGCATCTATGGCGATGAAGAACAACTTGTACGCGCACTGAGTAATCTGGTCAG
TAATGCATTACGCTACACGCCTGAAGGTGGTGAGATCGTGATTGAAGCCACCCGTCAGGGCCACCAGATCATGTTGAGCG
TCCAGGATACCGGTCCCGGTATTCCACCAGAACATCTGCCAAATGTCTTCGAGCGCTTCTACCGCATCGACGAATCACGC
CACACGGGCAGCGGCGGTTCGGGATTGGGATTGGCCATTGTGCGATCCATTGCCCAGGCCCACAATGGCACGGCTACAGT
ACACAGTACACCGGGAGCAGGAGCGCGCTTCACCATTGCCCTGCCAGCAGAGACAAAGAACGTCGTGCCGGTACCGTGA

Upstream 100 bases:

>100_bases
CCGCAAAATCGAGCCGGATCCCACCAATCCAACCTACATCGAAACTGTCTTCGGCATCGGGTACCGCTGCCGTCCACTGA
GTTAAGCCGGTGGAGGATGT

Downstream 100 bases:

>100_bases
TATTGTTTCCGGTAATAAAACCCAGCAACGCTATCGCGGTCGTTTTTTTATTCGACCGCTGTTTGTTTGTTACAACGAGC
AGCAACTGTTGCGTATGAAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MLRSLTTRLILAFALTSLVGIGLAALLVRQFVTNEFDTFLLEQQRNELLAQLITAYQETGDWNAATAILNGRSDREGGDP
FVPIEVADTEGRIVLSDRPAEIGRSVDPELLARGTPIMLNGEQIGTLLPLPPPRRNPAEERYLSRIDLALGGAAFGALGI
AIVLGFLLAQVITRPLRELMQGVRAIATGDLSRRVPVRSRDELGALAHQFNTMSAELQRATELRRRMTADIAHDLRTPLT
VIAGYLEALRDAELPATPARFAAMHTETQTLLRLVEDLHTLSLADAGELPLRCREIAVDDLLERIVRIYNDAAQQAGIRL
HRQSEPAGMRIYGDEEQLVRALSNLVSNALRYTPEGGEIVIEATRQGHQIMLSVQDTGPGIPPEHLPNVFERFYRIDESR
HTGSGGSGLGLAIVRSIAQAHNGTATVHSTPGAGARFTIALPAETKNVVPVP

Sequences:

>Translated_452_residues
MLRSLTTRLILAFALTSLVGIGLAALLVRQFVTNEFDTFLLEQQRNELLAQLITAYQETGDWNAATAILNGRSDREGGDP
FVPIEVADTEGRIVLSDRPAEIGRSVDPELLARGTPIMLNGEQIGTLLPLPPPRRNPAEERYLSRIDLALGGAAFGALGI
AIVLGFLLAQVITRPLRELMQGVRAIATGDLSRRVPVRSRDELGALAHQFNTMSAELQRATELRRRMTADIAHDLRTPLT
VIAGYLEALRDAELPATPARFAAMHTETQTLLRLVEDLHTLSLADAGELPLRCREIAVDDLLERIVRIYNDAAQQAGIRL
HRQSEPAGMRIYGDEEQLVRALSNLVSNALRYTPEGGEIVIEATRQGHQIMLSVQDTGPGIPPEHLPNVFERFYRIDESR
HTGSGGSGLGLAIVRSIAQAHNGTATVHSTPGAGARFTIALPAETKNVVPVP
>Mature_452_residues
MLRSLTTRLILAFALTSLVGIGLAALLVRQFVTNEFDTFLLEQQRNELLAQLITAYQETGDWNAATAILNGRSDREGGDP
FVPIEVADTEGRIVLSDRPAEIGRSVDPELLARGTPIMLNGEQIGTLLPLPPPRRNPAEERYLSRIDLALGGAAFGALGI
AIVLGFLLAQVITRPLRELMQGVRAIATGDLSRRVPVRSRDELGALAHQFNTMSAELQRATELRRRMTADIAHDLRTPLT
VIAGYLEALRDAELPATPARFAAMHTETQTLLRLVEDLHTLSLADAGELPLRCREIAVDDLLERIVRIYNDAAQQAGIRL
HRQSEPAGMRIYGDEEQLVRALSNLVSNALRYTPEGGEIVIEATRQGHQIMLSVQDTGPGIPPEHLPNVFERFYRIDESR
HTGSGGSGLGLAIVRSIAQAHNGTATVHSTPGAGARFTIALPAETKNVVPVP

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=336, Percent_Identity=36.0119047619048, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=40.0900900900901, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1786783, Length=308, Percent_Identity=33.1168831168831, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790346, Length=270, Percent_Identity=32.5925925925926, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=30.1724137931034, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1790861, Length=332, Percent_Identity=30.421686746988, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI87081816, Length=352, Percent_Identity=28.6931818181818, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=29.8701298701299, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1789149, Length=328, Percent_Identity=25.3048780487805, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788279, Length=327, Percent_Identity=29.3577981651376, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1787894, Length=291, Percent_Identity=30.5841924398625, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=32.15859030837, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788713, Length=257, Percent_Identity=28.4046692607004, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789403, Length=222, Percent_Identity=34.2342342342342, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790551, Length=258, Percent_Identity=31.3953488372093, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787374, Length=284, Percent_Identity=26.7605633802817, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=29.3577981651376, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789808, Length=303, Percent_Identity=25.0825082508251, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=218, Percent_Identity=27.9816513761468, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=305, Percent_Identity=23.9344262295082, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790300, Length=255, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322044, Length=80, Percent_Identity=41.25, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49217; Mature: 49217

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSLTTRLILAFALTSLVGIGLAALLVRQFVTNEFDTFLLEQQRNELLAQLITAYQETG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DWNAATAILNGRSDREGGDPFVPIEVADTEGRIVLSDRPAEIGRSVDPELLARGTPIMLN
CCCHHHHEECCCCCCCCCCCEEEEEEECCCCEEEECCCCHHHCCCCCHHHHHCCCCEEEC
GEQIGTLLPLPPPRRNPAEERYLSRIDLALGGAAFGALGIAIVLGFLLAQVITRPLRELM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGVRAIATGDLSRRVPVRSRDELGALAHQFNTMSAELQRATELRRRMTADIAHDLRTPLT
HHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAGYLEALRDAELPATPARFAAMHTETQTLLRLVEDLHTLSLADAGELPLRCREIAVDD
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LLERIVRIYNDAAQQAGIRLHRQSEPAGMRIYGDEEQLVRALSNLVSNALRYTPEGGEIV
HHHHHHHHHHHHHHHCCCEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEE
IEATRQGHQIMLSVQDTGPGIPPEHLPNVFERFYRIDESRHTGSGGSGLGLAIVRSIAQA
EEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
HNGTATVHSTPGAGARFTIALPAETKNVVPVP
CCCCEEEECCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLRSLTTRLILAFALTSLVGIGLAALLVRQFVTNEFDTFLLEQQRNELLAQLITAYQETG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DWNAATAILNGRSDREGGDPFVPIEVADTEGRIVLSDRPAEIGRSVDPELLARGTPIMLN
CCCHHHHEECCCCCCCCCCCEEEEEEECCCCEEEECCCCHHHCCCCCHHHHHCCCCEEEC
GEQIGTLLPLPPPRRNPAEERYLSRIDLALGGAAFGALGIAIVLGFLLAQVITRPLRELM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGVRAIATGDLSRRVPVRSRDELGALAHQFNTMSAELQRATELRRRMTADIAHDLRTPLT
HHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAGYLEALRDAELPATPARFAAMHTETQTLLRLVEDLHTLSLADAGELPLRCREIAVDD
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LLERIVRIYNDAAQQAGIRLHRQSEPAGMRIYGDEEQLVRALSNLVSNALRYTPEGGEIV
HHHHHHHHHHHHHHHCCCEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEE
IEATRQGHQIMLSVQDTGPGIPPEHLPNVFERFYRIDESRHTGSGGSGLGLAIVRSIAQA
EEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
HNGTATVHSTPGAGARFTIALPAETKNVVPVP
CCCCEEEECCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]