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The map label for this gene is prpC [H]

Identifier: 222527333

GI number: 222527333

Start: 5100255

End: 5101205

Strand: Reverse

Name: prpC [H]

Synonym: Chy400_4119

Alternate gene names: 222527333

Gene position: 5101205-5100255 (Counterclockwise)

Preceding gene: 222527334

Following gene: 222527332

Centisome position: 96.82

GC content: 57.52

Gene sequence:

>951_bases
ATGTCGGATGAAACAACTCCTGCAGCGGACGAAACGCCGACCGAACCGTTAAGTCAGGCCGACATTGAAGCTGAGCGCGA
ACGACTGCAGCGCCTGACGCCGCCAGAAGAAGATGGCACCCGCAAGATCGGGCAGGATTATCAGCCAGCCCTGACGCTAC
GCCGTTCAGCGCAGGGTTTTGCCGCTGCTGCATTACGTGACATTGGGCGTGTGCGTGAAGCAAATCAGGACTGTGCTCTG
GCTACGATTATGACCCTTCCCCGTGAGGGGAGTGATGTTGCTATAGGTCTATTCATCGTCGCTGATGGTATGGGAGGCCA
TCAGGGTGGTGAGGTAGCCAGCCGGCTGGCAGTGCAGACGGTGCTCACCAGCGTGCTTGAGCGGCTGGTGTTGCCAGTGA
TTGAGGATGGTTTGATCGAAGCGTTGCAGCCGTTGATGATTGAGGCCGTGCAGGAGGCAAACGCGGCGATCTGGCGGGAA
GCCCAGGCGACCGGTTCCGATATGGGTACCACCTGTACCGCCGCTCTGGTGATTGGGAACGGCCTGTACATCGCCCATGT
AGGTGACTCTCGGTGCTATGTGTACGAACCGGGTGGATTACGTCTGCTTACAACTGATCACTCGACGGTGGGGCGTCTGA
TTGCATTAGGACAGCTCGACCCGGAAGAGGCGCGTGATCATCCCCTGCGTAATCAGCTTTACCGTACCGTCGGGCAACAA
CCGCAGATAGCAGTGGATTTTGTCTACCACCAGTTGACCAACTGCTCGCATCTGGTTCTCTGTAGTGATGGTCTGTGGAG
TCTGGTTGAGGAAAAGGCTATCGAGCAAGCGCTGCGTCATAGTCCCTGGCCGCATGATGTCTGTCGAGAGTTGATCGCGC
TGGCCAATCTGGCCGGCGGCGACGATAATATTTCGGCGGTGGTTGTTTCGTTGCCGCTCGATGAGGCATAG

Upstream 100 bases:

>100_bases
CCCCGATGATTGTCAATGGCATTGTCTACATCGGTTCCATGGATCATCATCTCTACGCTTTGAAAGCGTAAGTTCGATAG
AGCGAAGGGAATTGGGGCTT

Downstream 100 bases:

>100_bases
CTATGAGTAAGGTTGACCTGCGCATCACGCCCAGTCGAAGTGTCTTACCGGCCAGTCAAGAGCCGCAGTTGCTTTATGCC
CTTGTCGAGCTATCGGCGCA

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSDETTPAADETPTEPLSQADIEAERERLQRLTPPEEDGTRKIGQDYQPALTLRRSAQGFAAAALRDIGRVREANQDCAL
ATIMTLPREGSDVAIGLFIVADGMGGHQGGEVASRLAVQTVLTSVLERLVLPVIEDGLIEALQPLMIEAVQEANAAIWRE
AQATGSDMGTTCTAALVIGNGLYIAHVGDSRCYVYEPGGLRLLTTDHSTVGRLIALGQLDPEEARDHPLRNQLYRTVGQQ
PQIAVDFVYHQLTNCSHLVLCSDGLWSLVEEKAIEQALRHSPWPHDVCRELIALANLAGGDDNISAVVVSLPLDEA

Sequences:

>Translated_316_residues
MSDETTPAADETPTEPLSQADIEAERERLQRLTPPEEDGTRKIGQDYQPALTLRRSAQGFAAAALRDIGRVREANQDCAL
ATIMTLPREGSDVAIGLFIVADGMGGHQGGEVASRLAVQTVLTSVLERLVLPVIEDGLIEALQPLMIEAVQEANAAIWRE
AQATGSDMGTTCTAALVIGNGLYIAHVGDSRCYVYEPGGLRLLTTDHSTVGRLIALGQLDPEEARDHPLRNQLYRTVGQQ
PQIAVDFVYHQLTNCSHLVLCSDGLWSLVEEKAIEQALRHSPWPHDVCRELIALANLAGGDDNISAVVVSLPLDEA
>Mature_315_residues
SDETTPAADETPTEPLSQADIEAERERLQRLTPPEEDGTRKIGQDYQPALTLRRSAQGFAAAALRDIGRVREANQDCALA
TIMTLPREGSDVAIGLFIVADGMGGHQGGEVASRLAVQTVLTSVLERLVLPVIEDGLIEALQPLMIEAVQEANAAIWREA
QATGSDMGTTCTAALVIGNGLYIAHVGDSRCYVYEPGGLRLLTTDHSTVGRLIALGQLDPEEARDHPLRNQLYRTVGQQP
QIAVDFVYHQLTNCSHLVLCSDGLWSLVEEKAIEQALRHSPWPHDVCRELIALANLAGGDDNISAVVVSLPLDEA

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 34098; Mature: 33967

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDETTPAADETPTEPLSQADIEAERERLQRLTPPEEDGTRKIGQDYQPALTLRRSAQGF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHCCHH
AAAALRDIGRVREANQDCALATIMTLPREGSDVAIGLFIVADGMGGHQGGEVASRLAVQT
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHH
VLTSVLERLVLPVIEDGLIEALQPLMIEAVQEANAAIWREAQATGSDMGTTCTAALVIGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEECC
GLYIAHVGDSRCYVYEPGGLRLLTTDHSTVGRLIALGQLDPEEARDHPLRNQLYRTVGQQ
CEEEEEECCCEEEEECCCCEEEEECCCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCC
PQIAVDFVYHQLTNCSHLVLCSDGLWSLVEEKAIEQALRHSPWPHDVCRELIALANLAGG
CCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
DDNISAVVVSLPLDEA
CCCCEEEEEEECCCCC
>Mature Secondary Structure 
SDETTPAADETPTEPLSQADIEAERERLQRLTPPEEDGTRKIGQDYQPALTLRRSAQGF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHCCHH
AAAALRDIGRVREANQDCALATIMTLPREGSDVAIGLFIVADGMGGHQGGEVASRLAVQT
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHH
VLTSVLERLVLPVIEDGLIEALQPLMIEAVQEANAAIWREAQATGSDMGTTCTAALVIGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEECC
GLYIAHVGDSRCYVYEPGGLRLLTTDHSTVGRLIALGQLDPEEARDHPLRNQLYRTVGQQ
CEEEEEECCCEEEEECCCCEEEEECCCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCC
PQIAVDFVYHQLTNCSHLVLCSDGLWSLVEEKAIEQALRHSPWPHDVCRELIALANLAGG
CCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
DDNISAVVVSLPLDEA
CCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]