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The map label for this gene is kptA [H]

Identifier: 222527254

GI number: 222527254

Start: 4987704

End: 4988252

Strand: Direct

Name: kptA [H]

Synonym: Chy400_4038

Alternate gene names: 222527254

Gene position: 4987704-4988252 (Clockwise)

Preceding gene: 222527253

Following gene: 222527257

Centisome position: 94.66

GC content: 57.19

Gene sequence:

>549_bases
ATGAAACAGCGCGAACTCATCCGCATCAGTAAGTTTCTCAGCCTGGTGCTGCGCCACCGTCCTGAACAGATCGGCTTAAG
CCTCGATCAACACGGCTGGGCAGAGGTTGATGAACTGATCCGGTGCGCCAATCGCCACGGCTTGCCGTTGAGTCGGGCGC
AGCTTGAACAGGTAGTTGCCGAAAACGACAAACAGCGCTTTGCCTTCAGTGCCGACGGTCGGCGGATTCGGGCAAATCAA
GGCCATTCGCTACCGGTTGATCTACAACTGACACCGGCACAACCGCCGCCTGTGCTCTACCACGGTACGGCGGAGCGCTT
CGTGGAATCGATCAAGCGTGATGGGTTACTCCCCGGCAAGCGGCAGTATGTACATCTTTCCCAAGACGAAACAACAGCGC
TTACCGTCGGGCAACGCCACGGTCGACCAGTTGTGTTGACGGTGCATGCCGCAGCGATGACGGCTGCCGGTTATGTGTTT
TACGTATCGGCAAATGGGGTATGGCTGACGAAGCAGGTGCCGGCAAGGTTTATTGAGTTTCCGGCATGA

Upstream 100 bases:

>100_bases
GACCCTTCAACGGTGTACTGCACTGCAAATGACGAGACATAGCAGGCAGAGTCAGGCAGATCAATGCTCAAAGCGTATCA
TTCTACCTTCTAACCGACAG

Downstream 100 bases:

>100_bases
TGGACGGGGTATCATCTGTACCGGCAGCGACACACGACCTGTGGAACGGGCTTTCGTTCCGCCTCGTCAATCGCCTGTAC
CACCGTTACATAACAGGAGT

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKQRELIRISKFLSLVLRHRPEQIGLSLDQHGWAEVDELIRCANRHGLPLSRAQLEQVVAENDKQRFAFSADGRRIRANQ
GHSLPVDLQLTPAQPPPVLYHGTAERFVESIKRDGLLPGKRQYVHLSQDETTALTVGQRHGRPVVLTVHAAAMTAAGYVF
YVSANGVWLTKQVPARFIEFPA

Sequences:

>Translated_182_residues
MKQRELIRISKFLSLVLRHRPEQIGLSLDQHGWAEVDELIRCANRHGLPLSRAQLEQVVAENDKQRFAFSADGRRIRANQ
GHSLPVDLQLTPAQPPPVLYHGTAERFVESIKRDGLLPGKRQYVHLSQDETTALTVGQRHGRPVVLTVHAAAMTAAGYVF
YVSANGVWLTKQVPARFIEFPA
>Mature_182_residues
MKQRELIRISKFLSLVLRHRPEQIGLSLDQHGWAEVDELIRCANRHGLPLSRAQLEQVVAENDKQRFAFSADGRRIRANQ
GHSLPVDLQLTPAQPPPVLYHGTAERFVESIKRDGLLPGKRQYVHLSQDETTALTVGQRHGRPVVLTVHAAAMTAAGYVF
YVSANGVWLTKQVPARFIEFPA

Specific function: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP- ribosy

COG id: COG1859

COG function: function code J; RNA:NAD 2'-phosphotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kptA/TPT1 family [H]

Homologues:

Organism=Homo sapiens, GI238550169, Length=181, Percent_Identity=35.9116022099448, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI238550157, Length=180, Percent_Identity=34.4444444444444, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI238550153, Length=180, Percent_Identity=34.4444444444444, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI238550149, Length=182, Percent_Identity=34.0659340659341, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI238550165, Length=135, Percent_Identity=37.037037037037, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI87082424, Length=179, Percent_Identity=54.1899441340782, Blast_Score=202, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6324470, Length=193, Percent_Identity=29.5336787564767, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022928
- InterPro:   IPR002745 [H]

Pfam domain/function: PF01885 PTS_2-RNA [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 20446; Mature: 20446

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRELIRISKFLSLVLRHRPEQIGLSLDQHGWAEVDELIRCANRHGLPLSRAQLEQVVA
CCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ENDKQRFAFSADGRRIRANQGHSLPVDLQLTPAQPPPVLYHGTAERFVESIKRDGLLPGK
CCCCCEEEECCCCCEEECCCCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCCC
RQYVHLSQDETTALTVGQRHGRPVVLTVHAAAMTAAGYVFYVSANGVWLTKQVPARFIEF
CEEEEECCCCCEEEEECCCCCCEEEEEEEHHHHHHCCEEEEEECCCEEEECCCCHHHHCC
PA
CC
>Mature Secondary Structure
MKQRELIRISKFLSLVLRHRPEQIGLSLDQHGWAEVDELIRCANRHGLPLSRAQLEQVVA
CCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ENDKQRFAFSADGRRIRANQGHSLPVDLQLTPAQPPPVLYHGTAERFVESIKRDGLLPGK
CCCCCEEEECCCCCEEECCCCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCCC
RQYVHLSQDETTALTVGQRHGRPVVLTVHAAAMTAAGYVFYVSANGVWLTKQVPARFIEF
CEEEEECCCCCEEEEECCCCCCEEEEEEEHHHHHHCCEEEEEECCCEEEECCCCHHHHCC
PA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]