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The map label for this gene is xseA [H]

Identifier: 222527251

GI number: 222527251

Start: 4985105

End: 4986298

Strand: Reverse

Name: xseA [H]

Synonym: Chy400_4035

Alternate gene names: 222527251

Gene position: 4986298-4985105 (Counterclockwise)

Preceding gene: 222527252

Following gene: 222527250

Centisome position: 94.64

GC content: 59.21

Gene sequence:

>1194_bases
ATGCGTGCATTTACGGTATCCGATCTCAATAGTGCACTGCGTGCTCATCTGGAAGACGAAGGCTTGTTCTTCGACATCTG
GCTGCTGGCGGAAGTGGTAGAGTTTCGACGCTACCCTTCCGGCCATTGCTATTTTACGCTGAAAGATGAGCAGGCGAGTA
TTCGGGCTGTCCTCTGGCGCTCGAAAGCTGAACAAATCGCCTTGTTGCCGGCTAATGGTGACGCTGTCCTGGCGCACGGA
CGGGTCGGTTTCTATGAGGCACGCGGTGAGTTGCAGTTTGTCGTTGATCAGATTGTGCCAGCCGGTGTTGGGTTGCTCAA
TGCCCAACTGGAACATCTGCGCGCTCGTCTCGAAGCAGAAGGACTCTTCGACGAACGCCGTAAGCGACTGTTGCCGGTTC
TGCCTCGTCGTATCGGCATTGTCACATCGCCACAGGCGGCTGCTTTGCAAGATATGCTCACTATTCTGCGCCGTCGCTAT
CCATTAGCTGAAGTCATCCTCTCGCCGTGTCTGGTGCAGGGTGAGTTAGCGCCGGCCAGTATTGTCGCCGCGTTGCGGCG
TGCTTACGCCGAACCGCTCGATGTGATCATTCTGGCCCGTGGCGGTGGCGCCAGCGACGATCTGGCTGCGTTTAATGATG
AACAGGTTGTACGCACAGTGGCTGCCAGCCCGGTGCCGATTATTACCGGTGTTGGTCACGAGACCGATACGACACTGGTT
GATGCAGTGGCCGATGTCCGTGCACCGACCCCCTCAGCCGCTGCCGAGCTGGTCGCGCCGCCGCTCGCCGATCTGCGGCA
GCGGGTTATCGATCTGCGTGAACGGGCAGAAGTGGCGCTTTTGACCGGCATCGATGCCCAACGCAGTGAAGTAGCCCGGC
AGCGGCTACTGTTGCAGCGTCATCATCCCCGTCGCCGGCTCGATGCAGCCCGCCAGACGATTGATGATCTGATGCTGCGG
CTGGATCGCGCCTTTTCCCGCTGGCTTCAACTTGAGCGCACACGCCTGCATGGTCTCCATTCCCGTCTGAACACGCTTAG
CCCGCAGGCAACTCTTGCCCGTGGGTATGCGATTGCCCAGCACGCCGATGGGCGAGTCATTACCGATTCATCTCAGGTAC
AGACCGGTGAGCGCATCGCGCTGACGCTGCGCGCCGGGATTGTACACGCAACTGTGGAGTCGACGAATGAGTGA

Upstream 100 bases:

>100_bases
AGATCGAGAGCGATGTGGCCGGTCGGGTTGCCCGCATTCTGGTCAAGAATGGTCAGCCGGTCGAGTATGGGCAACCACTG
ATGGTGATCGAACCACTCTA

Downstream 100 bases:

>100_bases
GCCGAATCCAGTTGAGCAGTACGAGCGATTACTGGCCGAGTTGCAACAGATTGTCGAACGCCTTGAACGCGGCGAATTGT
CACTGGCTGAAGCGTTGCAC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MRAFTVSDLNSALRAHLEDEGLFFDIWLLAEVVEFRRYPSGHCYFTLKDEQASIRAVLWRSKAEQIALLPANGDAVLAHG
RVGFYEARGELQFVVDQIVPAGVGLLNAQLEHLRARLEAEGLFDERRKRLLPVLPRRIGIVTSPQAAALQDMLTILRRRY
PLAEVILSPCLVQGELAPASIVAALRRAYAEPLDVIILARGGGASDDLAAFNDEQVVRTVAASPVPIITGVGHETDTTLV
DAVADVRAPTPSAAAELVAPPLADLRQRVIDLRERAEVALLTGIDAQRSEVARQRLLLQRHHPRRRLDAARQTIDDLMLR
LDRAFSRWLQLERTRLHGLHSRLNTLSPQATLARGYAIAQHADGRVITDSSQVQTGERIALTLRAGIVHATVESTNE

Sequences:

>Translated_397_residues
MRAFTVSDLNSALRAHLEDEGLFFDIWLLAEVVEFRRYPSGHCYFTLKDEQASIRAVLWRSKAEQIALLPANGDAVLAHG
RVGFYEARGELQFVVDQIVPAGVGLLNAQLEHLRARLEAEGLFDERRKRLLPVLPRRIGIVTSPQAAALQDMLTILRRRY
PLAEVILSPCLVQGELAPASIVAALRRAYAEPLDVIILARGGGASDDLAAFNDEQVVRTVAASPVPIITGVGHETDTTLV
DAVADVRAPTPSAAAELVAPPLADLRQRVIDLRERAEVALLTGIDAQRSEVARQRLLLQRHHPRRRLDAARQTIDDLMLR
LDRAFSRWLQLERTRLHGLHSRLNTLSPQATLARGYAIAQHADGRVITDSSQVQTGERIALTLRAGIVHATVESTNE
>Mature_397_residues
MRAFTVSDLNSALRAHLEDEGLFFDIWLLAEVVEFRRYPSGHCYFTLKDEQASIRAVLWRSKAEQIALLPANGDAVLAHG
RVGFYEARGELQFVVDQIVPAGVGLLNAQLEHLRARLEAEGLFDERRKRLLPVLPRRIGIVTSPQAAALQDMLTILRRRY
PLAEVILSPCLVQGELAPASIVAALRRAYAEPLDVIILARGGGASDDLAAFNDEQVVRTVAASPVPIITGVGHETDTTLV
DAVADVRAPTPSAAAELVAPPLADLRQRVIDLRERAEVALLTGIDAQRSEVARQRLLLQRHHPRRRLDAARQTIDDLMLR
LDRAFSRWLQLERTRLHGLHSRLNTLSPQATLARGYAIAQHADGRVITDSSQVQTGERIALTLRAGIVHATVESTNE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=437, Percent_Identity=36.1556064073227, Blast_Score=268, Evalue=6e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 43820; Mature: 43820

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFTVSDLNSALRAHLEDEGLFFDIWLLAEVVEFRRYPSGHCYFTLKDEQASIRAVLWR
CCEEEHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHH
SKAEQIALLPANGDAVLAHGRVGFYEARGELQFVVDQIVPAGVGLLNAQLEHLRARLEAE
CCCCEEEEEECCCCEEEEECCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHC
GLFDERRKRLLPVLPRRIGIVTSPQAAALQDMLTILRRRYPLAEVILSPCLVQGELAPAS
CCHHHHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHH
IVAALRRAYAEPLDVIILARGGGASDDLAAFNDEQVVRTVAASPVPIITGVGHETDTTLV
HHHHHHHHHCCCEEEEEEECCCCCCCCCHHCCHHHHHHHHHCCCCCEEECCCCCCCHHHH
DAVADVRAPTPSAAAELVAPPLADLRQRVIDLRERAEVALLTGIDAQRSEVARQRLLLQR
HHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHH
HHPRRRLDAARQTIDDLMLRLDRAFSRWLQLERTRLHGLHSRLNTLSPQATLARGYAIAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEE
HADGRVITDSSQVQTGERIALTLRAGIVHATVESTNE
CCCCCEEECCHHCCCCCEEEEEEECCEEEEECCCCCC
>Mature Secondary Structure
MRAFTVSDLNSALRAHLEDEGLFFDIWLLAEVVEFRRYPSGHCYFTLKDEQASIRAVLWR
CCEEEHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHH
SKAEQIALLPANGDAVLAHGRVGFYEARGELQFVVDQIVPAGVGLLNAQLEHLRARLEAE
CCCCEEEEEECCCCEEEEECCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHC
GLFDERRKRLLPVLPRRIGIVTSPQAAALQDMLTILRRRYPLAEVILSPCLVQGELAPAS
CCHHHHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHH
IVAALRRAYAEPLDVIILARGGGASDDLAAFNDEQVVRTVAASPVPIITGVGHETDTTLV
HHHHHHHHHCCCEEEEEEECCCCCCCCCHHCCHHHHHHHHHCCCCCEEECCCCCCCHHHH
DAVADVRAPTPSAAAELVAPPLADLRQRVIDLRERAEVALLTGIDAQRSEVARQRLLLQR
HHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHH
HHPRRRLDAARQTIDDLMLRLDRAFSRWLQLERTRLHGLHSRLNTLSPQATLARGYAIAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEE
HADGRVITDSSQVQTGERIALTLRAGIVHATVESTNE
CCCCCEEECCHHCCCCCEEEEEEECCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA