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The map label for this gene is gap1 [H]

Identifier: 222527240

GI number: 222527240

Start: 4973710

End: 4974735

Strand: Reverse

Name: gap1 [H]

Synonym: Chy400_4024

Alternate gene names: 222527240

Gene position: 4974735-4973710 (Counterclockwise)

Preceding gene: 222527245

Following gene: 222527238

Centisome position: 94.42

GC content: 57.7

Gene sequence:

>1026_bases
ATGGTTCGCGTCGCTATCAACGGTTTCGGCCGGATCGGACGCCAGAGCTTCAAGGCAATGCTGGAGTATTACCCCGAAGA
GTTCGAGATCGTCGCTATCAACGACCTGACCGACGCGCAAACGCTGGCCCATCTTCTGCGCTACGATTCGACCTATGGTG
CCTTCGATGGCGAAGTAACGGTGACCGAGAAGGCGATTGTGGTAGAGCAGGACGATATTCGCTACGAGTTGTTGACGCTG
GCCGAGCGCGACCCGGCAGCATTGCCCTGGAAGGAGCTGGGGGTTGACATCGTGATCGAGTCGACCGGCCGTTTCACCGA
TGCGGAAAAGGCCAAGGCTCACCTCGCGGCGGGTGCGAAGAAAGTGATCATTACGGCACCGGCGAAAGGTGAGGACATCA
CCATCTGTCTGGGTGTGAACGACGCGAAATACGATCACGAGAAGCATCACATCATCTCGAATGCATCCTGCACAACCAAC
TGTCTGGCACCGGTAGCGAAGGTGCTCAATGATCGCTTCGGGATCGAGCGTGGTCTGATGACGACCATCCACTCGTACAC
GATGGATCAAAACTTGCAGGATAACGTACACAAGGATTTGCGCCGGGCGCGGGCTGCGGCTATCAACATGGTGCCAACGA
CCACTGGTGCCGCGAAGGCGGTGGCGCTGGTTATTCCCGAATTGAAAGGCAAGTTCCACGGTTATGCCGTGCGCGTGCCG
ACGCCGACGGTGTCGATGGTTGACTTCTCGGTGCTGCTGAGCACCAAGACCTCGGTCGAGGAGATTAACCAGGCCTTCAT
CGAAGCCAGCGAGAGCGAAGAGCTTGAGGGCATTCTCGGCGTGAGCCACGATCCGCTGGTTAGCACCGACTTCATCGGTA
CCACCTACAGCAGTGTAGTCGATTTACCGCTCACAATGAGCATGGGCGACGATTTCTTCAAGATCGTGGCCTGGTACGAC
AACGAGTGGGGCTATTCGGTGCGGGTCGCCGATCTGACCGCACTGGTGGCAGACCGCTTCGAGTAG

Upstream 100 bases:

>100_bases
TGCTATAATGACCGCGTCAGTCAATGGCAACAGGTCATGCCATTGCGGCTCACGGCCCGCTGGCCTGAGCACCTTTGTTT
GAGCATTTAAGGAGGCTTAC

Downstream 100 bases:

>100_bases
AGTGTTCACGCGGTGACACAACACGGCAGGGACTGCTCAATTGCCAGTCCCTGCCGTTTATGTTAGTTCAAATCTGAAGA
ATACAATGCGCGTCACGCGA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH 1 [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MVRVAINGFGRIGRQSFKAMLEYYPEEFEIVAINDLTDAQTLAHLLRYDSTYGAFDGEVTVTEKAIVVEQDDIRYELLTL
AERDPAALPWKELGVDIVIESTGRFTDAEKAKAHLAAGAKKVIITAPAKGEDITICLGVNDAKYDHEKHHIISNASCTTN
CLAPVAKVLNDRFGIERGLMTTIHSYTMDQNLQDNVHKDLRRARAAAINMVPTTTGAAKAVALVIPELKGKFHGYAVRVP
TPTVSMVDFSVLLSTKTSVEEINQAFIEASESEELEGILGVSHDPLVSTDFIGTTYSSVVDLPLTMSMGDDFFKIVAWYD
NEWGYSVRVADLTALVADRFE

Sequences:

>Translated_341_residues
MVRVAINGFGRIGRQSFKAMLEYYPEEFEIVAINDLTDAQTLAHLLRYDSTYGAFDGEVTVTEKAIVVEQDDIRYELLTL
AERDPAALPWKELGVDIVIESTGRFTDAEKAKAHLAAGAKKVIITAPAKGEDITICLGVNDAKYDHEKHHIISNASCTTN
CLAPVAKVLNDRFGIERGLMTTIHSYTMDQNLQDNVHKDLRRARAAAINMVPTTTGAAKAVALVIPELKGKFHGYAVRVP
TPTVSMVDFSVLLSTKTSVEEINQAFIEASESEELEGILGVSHDPLVSTDFIGTTYSSVVDLPLTMSMGDDFFKIVAWYD
NEWGYSVRVADLTALVADRFE
>Mature_341_residues
MVRVAINGFGRIGRQSFKAMLEYYPEEFEIVAINDLTDAQTLAHLLRYDSTYGAFDGEVTVTEKAIVVEQDDIRYELLTL
AERDPAALPWKELGVDIVIESTGRFTDAEKAKAHLAAGAKKVIITAPAKGEDITICLGVNDAKYDHEKHHIISNASCTTN
CLAPVAKVLNDRFGIERGLMTTIHSYTMDQNLQDNVHKDLRRARAAAINMVPTTTGAAKAVALVIPELKGKFHGYAVRVP
TPTVSMVDFSVLLSTKTSVEEINQAFIEASESEELEGILGVSHDPLVSTDFIGTTYSSVVDLPLTMSMGDDFFKIVAWYD
NEWGYSVRVADLTALVADRFE

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=338, Percent_Identity=43.1952662721894, Blast_Score=283, Evalue=1e-76,
Organism=Homo sapiens, GI7669492, Length=340, Percent_Identity=45.8823529411765, Blast_Score=280, Evalue=9e-76,
Organism=Escherichia coli, GI1788079, Length=337, Percent_Identity=49.8516320474777, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI1789295, Length=338, Percent_Identity=43.1952662721894, Blast_Score=268, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI17534679, Length=340, Percent_Identity=46.7647058823529, Blast_Score=301, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17534677, Length=340, Percent_Identity=46.4705882352941, Blast_Score=301, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=47.1976401179941, Blast_Score=296, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=47.1976401179941, Blast_Score=296, Evalue=9e-81,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=48.9675516224189, Blast_Score=311, Evalue=8e-86,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=49.2625368731563, Blast_Score=308, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=46.6076696165192, Blast_Score=306, Evalue=3e-84,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=46.1077844311377, Blast_Score=281, Evalue=4e-76,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=46.1077844311377, Blast_Score=281, Evalue=4e-76,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=46.4071856287425, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=46.4071856287425, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI19922412, Length=334, Percent_Identity=44.9101796407186, Blast_Score=276, Evalue=2e-74,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37510; Mature: 37510

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRVAINGFGRIGRQSFKAMLEYYPEEFEIVAINDLTDAQTLAHLLRYDSTYGAFDGEVT
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEE
VTEKAIVVEQDDIRYELLTLAERDPAALPWKELGVDIVIESTGRFTDAEKAKAHLAAGAK
EEEEEEEEECCCCEEEEEEECCCCCCCCCHHHCCEEEEEECCCCCCCHHHHHHHHHCCCC
KVIITAPAKGEDITICLGVNDAKYDHEKHHIISNASCTTNCLAPVAKVLNDRFGIERGLM
EEEEECCCCCCEEEEEEECCCCCCCCCHHHEECCCCCCHHHHHHHHHHHHHHCCHHHHHH
TTIHSYTMDQNLQDNVHKDLRRARAAAINMVPTTTGAAKAVALVIPELKGKFHGYAVRVP
HHHHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHEEEEEEHHHCCCCCCEEEECC
TPTVSMVDFSVLLSTKTSVEEINQAFIEASESEELEGILGVSHDPLVSTDFIGTTYSSVV
CCCCHHHEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHH
DLPLTMSMGDDFFKIVAWYDNEWGYSVRVADLTALVADRFE
CCCEEECCCCCEEEEEEEEECCCCCEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MVRVAINGFGRIGRQSFKAMLEYYPEEFEIVAINDLTDAQTLAHLLRYDSTYGAFDGEVT
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEE
VTEKAIVVEQDDIRYELLTLAERDPAALPWKELGVDIVIESTGRFTDAEKAKAHLAAGAK
EEEEEEEEECCCCEEEEEEECCCCCCCCCHHHCCEEEEEECCCCCCCHHHHHHHHHCCCC
KVIITAPAKGEDITICLGVNDAKYDHEKHHIISNASCTTNCLAPVAKVLNDRFGIERGLM
EEEEECCCCCCEEEEEEECCCCCCCCCHHHEECCCCCCHHHHHHHHHHHHHHCCHHHHHH
TTIHSYTMDQNLQDNVHKDLRRARAAAINMVPTTTGAAKAVALVIPELKGKFHGYAVRVP
HHHHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHEEEEEEHHHCCCCCCEEEECC
TPTVSMVDFSVLLSTKTSVEEINQAFIEASESEELEGILGVSHDPLVSTDFIGTTYSSVV
CCCCHHHEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHH
DLPLTMSMGDDFFKIVAWYDNEWGYSVRVADLTALVADRFE
CCCEEECCCCCEEEEEEEEECCCCCEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA