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The map label for this gene is hit [H]

Identifier: 222527110

GI number: 222527110

Start: 4839848

End: 4840255

Strand: Reverse

Name: hit [H]

Synonym: Chy400_3891

Alternate gene names: 222527110

Gene position: 4840255-4839848 (Counterclockwise)

Preceding gene: 222527111

Following gene: 222527109

Centisome position: 91.86

GC content: 52.21

Gene sequence:

>408_bases
ATGACATCGGTCTTTACGCGAATTGTCCGCGGTGAAATTCCGGCGTTCAAGCTGTATGAAGATGATCTGACCCTCTCGTT
TCTTGACATCAATCCAGCAGCACGCGGTCATGCGCTGGTGATTGCCAAACCCGAATTGCCTGGTCTCCTCGACTTACCTC
CTGAGTTAGTTTCTGCTGTAGCTCTCACAACGCAGCGCGTTGCACGAGCAATTGTTGAGGCACTCAAACCGGATGGTTTC
AACGTCATTCAAAACAACGGTGCAGCCGCTGGCCAGGTTGTTTTTCACTATCACGTACATATTATTCCGCGCTGGGAAGG
GGATCGCTCGGTCAAGCTTTGGCGTCCCGGAACAATGAGTATGGACGATCTGCGGGCCGTTGCCGACGAGATACTCGCTC
ATATCTGA

Upstream 100 bases:

>100_bases
TATTGTTGGGAGTGATCGCACTGGCCTGGCTGAGCCGTCGTTCGGCCACAGCAGGTGTGCAAGACGATGTAACTTCGTTG
AGTGATGTTTCGGAGGTGCT

Downstream 100 bases:

>100_bases
GGTGTGACCGATGAGCGAATCTGTTTCTCCTCCGCCACCAACGACGAAAACTGAGCCGAACAGTGCTACGCCATCGACAC
CGGCACCGGCGGCAGAGCCT

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MTSVFTRIVRGEIPAFKLYEDDLTLSFLDINPAARGHALVIAKPELPGLLDLPPELVSAVALTTQRVARAIVEALKPDGF
NVIQNNGAAAGQVVFHYHVHIIPRWEGDRSVKLWRPGTMSMDDLRAVADEILAHI

Sequences:

>Translated_135_residues
MTSVFTRIVRGEIPAFKLYEDDLTLSFLDINPAARGHALVIAKPELPGLLDLPPELVSAVALTTQRVARAIVEALKPDGF
NVIQNNGAAAGQVVFHYHVHIIPRWEGDRSVKLWRPGTMSMDDLRAVADEILAHI
>Mature_134_residues
TSVFTRIVRGEIPAFKLYEDDLTLSFLDINPAARGHALVIAKPELPGLLDLPPELVSAVALTTQRVARAIVEALKPDGFN
VIQNNGAAAGQVVFHYHVHIIPRWEGDRSVKLWRPGTMSMDDLRAVADEILAHI

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Escherichia coli, GI1787346, Length=101, Percent_Identity=34.6534653465347, Blast_Score=60, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17506713, Length=118, Percent_Identity=36.4406779661017, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320078, Length=134, Percent_Identity=37.3134328358209, Blast_Score=93, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581222, Length=118, Percent_Identity=33.8983050847458, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574010, Length=118, Percent_Identity=33.8983050847458, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 14858; Mature: 14727

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVFTRIVRGEIPAFKLYEDDLTLSFLDINPAARGHALVIAKPELPGLLDLPPELVSAV
CCHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCHHHHHHH
ALTTQRVARAIVEALKPDGFNVIQNNGAAAGQVVFHYHVHIIPRWEGDRSVKLWRPGTMS
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEEEEECCCCCCEEEEECCCCCC
MDDLRAVADEILAHI
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSVFTRIVRGEIPAFKLYEDDLTLSFLDINPAARGHALVIAKPELPGLLDLPPELVSAV
CHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCHHHHHHH
ALTTQRVARAIVEALKPDGFNVIQNNGAAAGQVVFHYHVHIIPRWEGDRSVKLWRPGTMS
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEEEEECCCCCCEEEEECCCCCC
MDDLRAVADEILAHI
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]