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The map label for this gene is yabD [H]

Identifier: 222527099

GI number: 222527099

Start: 4826710

End: 4827501

Strand: Reverse

Name: yabD [H]

Synonym: Chy400_3879

Alternate gene names: 222527099

Gene position: 4827501-4826710 (Counterclockwise)

Preceding gene: 222527101

Following gene: 222527098

Centisome position: 91.62

GC content: 57.83

Gene sequence:

>792_bases
ATGAAATCTACACTACGCTTAATTGACACCCATCTCCATCTCGCGTCGGAACAATTCAACGAGGATCGCAGTGCGGTCAT
CTTGCGGGCCATCGATGCCGGGGTCGCAGCGATGATCGAGATTGGCTACGATCTGGCATCCAGTCACGCGGCAGTCGCGC
TGGCGAATGCGCATCCGGCGGTATTTGCGGTTGTTGGGATTCAGCCCAATCATCTGCACGATCTGCCAGGCGATTGGATT
GACCAGATACGCAGGCTGGCCGCCCATCCGAAGGTGGTCGCGATTGGTGAGATTGGTCTCGACTACTACTGGATGAAATC
GCCACCAAGTGAGCAGGATGCGGCGTTTCGTGCCCAACTGGCGCTGGCCGGTGAGCTGGGCTTGCCGGTTGTGATCCACT
CGCGAGATGCGATGGCCGAGACGATTGCCGTGTTGCGCGATGCCGCCCGTGGGCCGGGGATCATGCATTCATTCTCAGGT
GATTGGGCTGCTGCACAGGAGTGTTTGGAATTGGGCTTTTATCTCTCGCTGTCAGGCCCGCTGACGTTTCCCAAATCTGT
AGCCTTACACGAAGTAGCTCGTCTGGCACCGGCGGATCGGCTGTTGATCGAGACCGATAGCCCCTACCTCAGTCCCCATC
CACACCGTGGGCAGCGCAATGAACCGAGTCGACTGGTATATATCGGGCAGAAACTGGCTGAACTGCGTGGGCAGACGCTG
GACGCTCTGGCACCACAGCTCTGGCAGAATACGTTACACGCATTTCCCCGTCTGTCCACTGCTTTAGGATAG

Upstream 100 bases:

>100_bases
GTGCCCTGGGTCCGGCTGTGCTTCTGCACGTCTCACCGTCTCCCGTTATAATACACCTGACCTGGTATGGGCATGTATGC
TACAATGATGTGGGATGCCT

Downstream 100 bases:

>100_bases
CAAGTATGAACCGTTCTTCGTTGTCAGTTTCAACCAGTTCGCTGAACATCTGGTGGATGCTACCGGGTCTTGGGCTGATT
GGGCTTTTAACCGGTGCGGT

Product: hydrolase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKSTLRLIDTHLHLASEQFNEDRSAVILRAIDAGVAAMIEIGYDLASSHAAVALANAHPAVFAVVGIQPNHLHDLPGDWI
DQIRRLAAHPKVVAIGEIGLDYYWMKSPPSEQDAAFRAQLALAGELGLPVVIHSRDAMAETIAVLRDAARGPGIMHSFSG
DWAAAQECLELGFYLSLSGPLTFPKSVALHEVARLAPADRLLIETDSPYLSPHPHRGQRNEPSRLVYIGQKLAELRGQTL
DALAPQLWQNTLHAFPRLSTALG

Sequences:

>Translated_263_residues
MKSTLRLIDTHLHLASEQFNEDRSAVILRAIDAGVAAMIEIGYDLASSHAAVALANAHPAVFAVVGIQPNHLHDLPGDWI
DQIRRLAAHPKVVAIGEIGLDYYWMKSPPSEQDAAFRAQLALAGELGLPVVIHSRDAMAETIAVLRDAARGPGIMHSFSG
DWAAAQECLELGFYLSLSGPLTFPKSVALHEVARLAPADRLLIETDSPYLSPHPHRGQRNEPSRLVYIGQKLAELRGQTL
DALAPQLWQNTLHAFPRLSTALG
>Mature_263_residues
MKSTLRLIDTHLHLASEQFNEDRSAVILRAIDAGVAAMIEIGYDLASSHAAVALANAHPAVFAVVGIQPNHLHDLPGDWI
DQIRRLAAHPKVVAIGEIGLDYYWMKSPPSEQDAAFRAQLALAGELGLPVVIHSRDAMAETIAVLRDAARGPGIMHSFSG
DWAAAQECLELGFYLSLSGPLTFPKSVALHEVARLAPADRLLIETDSPYLSPHPHRGQRNEPSRLVYIGQKLAELRGQTL
DALAPQLWQNTLHAFPRLSTALG

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=295, Percent_Identity=28.4745762711864, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI225903439, Length=246, Percent_Identity=29.6747967479675, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=28.2527881040892, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=28.2527881040892, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI226061853, Length=277, Percent_Identity=28.5198555956679, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=27.2373540856031, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI225903424, Length=172, Percent_Identity=30.8139534883721, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI226061595, Length=236, Percent_Identity=28.3898305084746, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=36.9649805447471, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI48994985, Length=240, Percent_Identity=37.0833333333333, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082439, Length=254, Percent_Identity=32.2834645669291, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=213, Percent_Identity=29.5774647887324, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=26.2172284644195, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24648690, Length=286, Percent_Identity=31.4685314685315, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI221330018, Length=278, Percent_Identity=28.7769784172662, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24586117, Length=271, Percent_Identity=29.520295202952, Blast_Score=97, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28567; Mature: 28567

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTLRLIDTHLHLASEQFNEDRSAVILRAIDAGVAAMIEIGYDLASSHAAVALANAHPA
CCCHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCE
VFAVVGIQPNHLHDLPGDWIDQIRRLAAHPKVVAIGEIGLDYYWMKSPPSEQDAAFRAQL
EEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHH
ALAGELGLPVVIHSRDAMAETIAVLRDAARGPGIMHSFSGDWAAAQECLELGFYLSLSGP
HEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCEEEEECCC
LTFPKSVALHEVARLAPADRLLIETDSPYLSPHPHRGQRNEPSRLVYIGQKLAELRGQTL
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCHH
DALAPQLWQNTLHAFPRLSTALG
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSTLRLIDTHLHLASEQFNEDRSAVILRAIDAGVAAMIEIGYDLASSHAAVALANAHPA
CCCHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCE
VFAVVGIQPNHLHDLPGDWIDQIRRLAAHPKVVAIGEIGLDYYWMKSPPSEQDAAFRAQL
EEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHH
ALAGELGLPVVIHSRDAMAETIAVLRDAARGPGIMHSFSGDWAAAQECLELGFYLSLSGP
HEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCEEEEECCC
LTFPKSVALHEVARLAPADRLLIETDSPYLSPHPHRGQRNEPSRLVYIGQKLAELRGQTL
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCHH
DALAPQLWQNTLHAFPRLSTALG
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]