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The map label for this gene is luxQ [H]

Identifier: 222527091

GI number: 222527091

Start: 4817399

End: 4819063

Strand: Direct

Name: luxQ [H]

Synonym: Chy400_3870

Alternate gene names: 222527091

Gene position: 4817399-4819063 (Clockwise)

Preceding gene: 222527090

Following gene: 222527092

Centisome position: 91.43

GC content: 55.74

Gene sequence:

>1665_bases
ATGCGCTTTCCGATTCGCGTAAAGTTGTTGGGAGCACTGGCCATCGACCTCCTGTTGATGATGATCCTTGGCGTCTTTGC
CATGCATCAGATGGCCGTCATGAATGAACGTGCCGTCTTCATTGAACGTCACACAATCCCATCGCTCGACACGGTTGGCG
ATATGACAGCAGCGATCAATCGCTATCGTGCTCGCCAGCTCGAATTTCTGATTTATACCAACAACGGCGACCGTGCCCGC
ATCCTTGATCAGATGCGTGTGATTGAAACCGAAATGGCCGGCTACGTGCAGGCGTACCGTGCCCTAGTTGACTCCGAGAG
CGAACGTCGTCAATTAAATGCTGTTGAAGCAGCCTGGCACGAGGTGGTGCGCGCCAATCACGAACGCTTCATTCCGGCTG
TACGCCTGGTGAGCGATGGCAGTGTGCAGCCTTTCTATTCACGCATGAACCCCGTTTACGCCACGCTTGATCGGGAAATG
AACCTTCTGGTGCAAGAGAATCAGCAACAGGCACGGGCATCACTCGATGTTGTCGCCAGCAGTTATGCGACTGCGCGTAC
CTTCATCTTGTTCGATACAGCGGTTGCGATTATCATCTCGGCGGCGATTGGCTTGTTCCTGTCTGCCCGCATTGCACGTC
GGTTGCGACGACTGGCCCATGCTTCTAATCGCGTAGCCGCCGGTGACTTTGTCGGTTCCATCAATGAGCGGACTCGTGAT
GAGATTGGCGATCTGGCCCGCGCATTCGATCAGATGTTGAGCAGCCTGCGGGCACAACGTGCCGAACTGGAAGAACGCAA
CCGCGCACTGCAAGAGAGTCTCTCGCGTCAGGCGCAGTTGATGGAAGAGATTGTGCGTGGCAAACAGGCCGAAGCTGAAG
CAGAACGGGCGCGCGCTGCCGCAGAGGCCGCCAGTCAGGCCAAGAGCGCCTTTTTGGCGACAATGAGCCATGAACTACGT
ACTCCGCTCAATGCCATTCTCGGATACGCGCAGTTGCTGCATCTGAGTAATGCCGTGAGTGAACCGCACGCTGACTATCT
GGAGCGCATTCTCTCGTCTGGCCGTCATTTACTCACCTTGATCAGCGACGTACTCGATTTTGCCCGTATTGAACAGGGAG
CACTCGAACTGGAGTACCGCCAGGTTGCAATCGCACCACTGGTCGAAGATGTGGCAACAATGACGCTGCCCCTGGCGCAA
CGCAACCACAATCAGGTGATCACCTGTTACCCGGCGGACATTGGCTCTATCGAGACCGATGACCGCCGCTTGCGTCAGGT
TTTGATCAATCTCCTCGGTAATGCAGCTAAGTTTACCGAACGGGGAACAATTCGGCTTAATGTTGTGCGAGAGCAGCGCC
ACGGGATCGACGGCATTCGCTTCGACGTTATCGATACGGGGATTGGCATCCCCCGTGATAAGCAGGACAAACTCTTCAAA
CCGTTTAGCCAGATCGACGAGTCGGTCACCCGCCGTTATGAAGGCACCGGTCTCGGTCTGGCGCTCAGTAAGCAGATCGT
GCTGGCCCTTGGTGGCACAATTGACGTAGAGAGCGACTTTGGTGTTGGCTCAACCTTCACCGTTTGGCTGCCCACTGCAC
CTCTTGCTGCGGCAGACTCCACATCGTTACCATCGCAACCACACCTGATAGGAGAACCCGCATGA

Upstream 100 bases:

>100_bases
TACAGCGGGTGGAGCGACGGATCACCGGTTCCGTCTTTTCCGGCGGGTCGCAGGTCGGTCTATCAATCGAGCAACTGTTG
CAACTAGAGGATCGCTAGCG

Downstream 100 bases:

>100_bases
GCTATATTCTCGTTGTAGACGATAATTTCGATAATCGCCATATTATTGGACAGATGTTGCAATTCAGTGGCTTTACCGTT
GAGCTGGTTGCTGATGCCCA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MRFPIRVKLLGALAIDLLLMMILGVFAMHQMAVMNERAVFIERHTIPSLDTVGDMTAAINRYRARQLEFLIYTNNGDRAR
ILDQMRVIETEMAGYVQAYRALVDSESERRQLNAVEAAWHEVVRANHERFIPAVRLVSDGSVQPFYSRMNPVYATLDREM
NLLVQENQQQARASLDVVASSYATARTFILFDTAVAIIISAAIGLFLSARIARRLRRLAHASNRVAAGDFVGSINERTRD
EIGDLARAFDQMLSSLRAQRAELEERNRALQESLSRQAQLMEEIVRGKQAEAEAERARAAAEAASQAKSAFLATMSHELR
TPLNAILGYAQLLHLSNAVSEPHADYLERILSSGRHLLTLISDVLDFARIEQGALELEYRQVAIAPLVEDVATMTLPLAQ
RNHNQVITCYPADIGSIETDDRRLRQVLINLLGNAAKFTERGTIRLNVVREQRHGIDGIRFDVIDTGIGIPRDKQDKLFK
PFSQIDESVTRRYEGTGLGLALSKQIVLALGGTIDVESDFGVGSTFTVWLPTAPLAAADSTSLPSQPHLIGEPA

Sequences:

>Translated_554_residues
MRFPIRVKLLGALAIDLLLMMILGVFAMHQMAVMNERAVFIERHTIPSLDTVGDMTAAINRYRARQLEFLIYTNNGDRAR
ILDQMRVIETEMAGYVQAYRALVDSESERRQLNAVEAAWHEVVRANHERFIPAVRLVSDGSVQPFYSRMNPVYATLDREM
NLLVQENQQQARASLDVVASSYATARTFILFDTAVAIIISAAIGLFLSARIARRLRRLAHASNRVAAGDFVGSINERTRD
EIGDLARAFDQMLSSLRAQRAELEERNRALQESLSRQAQLMEEIVRGKQAEAEAERARAAAEAASQAKSAFLATMSHELR
TPLNAILGYAQLLHLSNAVSEPHADYLERILSSGRHLLTLISDVLDFARIEQGALELEYRQVAIAPLVEDVATMTLPLAQ
RNHNQVITCYPADIGSIETDDRRLRQVLINLLGNAAKFTERGTIRLNVVREQRHGIDGIRFDVIDTGIGIPRDKQDKLFK
PFSQIDESVTRRYEGTGLGLALSKQIVLALGGTIDVESDFGVGSTFTVWLPTAPLAAADSTSLPSQPHLIGEPA
>Mature_554_residues
MRFPIRVKLLGALAIDLLLMMILGVFAMHQMAVMNERAVFIERHTIPSLDTVGDMTAAINRYRARQLEFLIYTNNGDRAR
ILDQMRVIETEMAGYVQAYRALVDSESERRQLNAVEAAWHEVVRANHERFIPAVRLVSDGSVQPFYSRMNPVYATLDREM
NLLVQENQQQARASLDVVASSYATARTFILFDTAVAIIISAAIGLFLSARIARRLRRLAHASNRVAAGDFVGSINERTRD
EIGDLARAFDQMLSSLRAQRAELEERNRALQESLSRQAQLMEEIVRGKQAEAEAERARAAAEAASQAKSAFLATMSHELR
TPLNAILGYAQLLHLSNAVSEPHADYLERILSSGRHLLTLISDVLDFARIEQGALELEYRQVAIAPLVEDVATMTLPLAQ
RNHNQVITCYPADIGSIETDDRRLRQVLINLLGNAAKFTERGTIRLNVVREQRHGIDGIRFDVIDTGIGIPRDKQDKLFK
PFSQIDESVTRRYEGTGLGLALSKQIVLALGGTIDVESDFGVGSTFTVWLPTAPLAAADSTSLPSQPHLIGEPA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=352, Percent_Identity=32.1022727272727, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=40.080971659919, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI87081816, Length=343, Percent_Identity=36.1516034985423, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=35.5371900826446, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1788713, Length=245, Percent_Identity=33.8775510204082, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=32.7935222672065, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=32.3886639676113, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=31.4655172413793, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788393, Length=318, Percent_Identity=27.0440251572327, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=31.0043668122271, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=32.6086956521739, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=27.4678111587983, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=29.4372294372294, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=230, Percent_Identity=29.1304347826087, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=29.126213592233, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790551, Length=202, Percent_Identity=30.1980198019802, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=73, Percent_Identity=46.5753424657534, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61576; Mature: 61576

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFPIRVKLLGALAIDLLLMMILGVFAMHQMAVMNERAVFIERHTIPSLDTVGDMTAAIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHH
RYRARQLEFLIYTNNGDRARILDQMRVIETEMAGYVQAYRALVDSESERRQLNAVEAAWH
HHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EVVRANHERFIPAVRLVSDGSVQPFYSRMNPVYATLDREMNLLVQENQQQARASLDVVAS
HHHHCCHHHHHHHHHEECCCCCCHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SYATARTFILFDTAVAIIISAAIGLFLSARIARRLRRLAHASNRVAAGDFVGSINERTRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
EIGDLARAFDQMLSSLRAQRAELEERNRALQESLSRQAQLMEEIVRGKQAEAEAERARAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AEAASQAKSAFLATMSHELRTPLNAILGYAQLLHLSNAVSEPHADYLERILSSGRHLLTL
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
ISDVLDFARIEQGALELEYRQVAIAPLVEDVATMTLPLAQRNHNQVITCYPADIGSIETD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
DRRLRQVLINLLGNAAKFTERGTIRLNVVREQRHGIDGIRFDVIDTGIGIPRDKQDKLFK
HHHHHHHHHHHHCCHHHHCCCCCEEEEEEEHHHCCCCCEEEEEEECCCCCCCCCHHHHHC
PFSQIDESVTRRYEGTGLGLALSKQIVLALGGTIDVESDFGVGSTFTVWLPTAPLAAADS
CHHHHHHHHHHHHCCCCCCHHHHHHHHHEECCEEEECCCCCCCCEEEEEECCCCCCCCCC
TSLPSQPHLIGEPA
CCCCCCCCCCCCCC
>Mature Secondary Structure
MRFPIRVKLLGALAIDLLLMMILGVFAMHQMAVMNERAVFIERHTIPSLDTVGDMTAAIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHH
RYRARQLEFLIYTNNGDRARILDQMRVIETEMAGYVQAYRALVDSESERRQLNAVEAAWH
HHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EVVRANHERFIPAVRLVSDGSVQPFYSRMNPVYATLDREMNLLVQENQQQARASLDVVAS
HHHHCCHHHHHHHHHEECCCCCCHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SYATARTFILFDTAVAIIISAAIGLFLSARIARRLRRLAHASNRVAAGDFVGSINERTRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
EIGDLARAFDQMLSSLRAQRAELEERNRALQESLSRQAQLMEEIVRGKQAEAEAERARAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AEAASQAKSAFLATMSHELRTPLNAILGYAQLLHLSNAVSEPHADYLERILSSGRHLLTL
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
ISDVLDFARIEQGALELEYRQVAIAPLVEDVATMTLPLAQRNHNQVITCYPADIGSIETD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
DRRLRQVLINLLGNAAKFTERGTIRLNVVREQRHGIDGIRFDVIDTGIGIPRDKQDKLFK
HHHHHHHHHHHHCCHHHHCCCCCEEEEEEEHHHCCCCCEEEEEEECCCCCCCCCHHHHHC
PFSQIDESVTRRYEGTGLGLALSKQIVLALGGTIDVESDFGVGSTFTVWLPTAPLAAADS
CHHHHHHHHHHHHCCCCCCHHHHHHHHHEECCEEEECCCCCCCCEEEEEECCCCCCCCCC
TSLPSQPHLIGEPA
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]