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The map label for this gene is ziaR [H]

Identifier: 222527089

GI number: 222527089

Start: 4815710

End: 4816093

Strand: Reverse

Name: ziaR [H]

Synonym: Chy400_3868

Alternate gene names: 222527089

Gene position: 4816093-4815710 (Counterclockwise)

Preceding gene: 222527098

Following gene: 222527088

Centisome position: 91.41

GC content: 58.07

Gene sequence:

>384_bases
ATGAATGCACAGCCTACAGATCAGGAAACACCAGCCGTGCAGGTGATGTCTTGCTGTGCACCGGCGATCACGGTCACGCT
CAGCGATGCTGAGGCTGCGCAGCTTGCCGATGCATTGTCGTTGCTTGCGCATCCGATCCGTCTGCGCTTGCTGGCCATTC
TGGCCCGCAATGCCGGTCACGTCTGCGTTTGTGATCTTGAAGCGGCCCTTCCTGTCAAGCAGCCAACCGTTTCGCACCAC
CTGCGATTGCTGCGCGATGGTGGTCTGATCGAGGGCGAGCGGCGCGGGCAGTGGATTTATTACGCGATTCGCCAGGATGC
ACTGGCAACAGTGCGGTTGTTGATCGATCAGTTTTTTGCCTCTCTTACGCCGGATAAGGCTTGA

Upstream 100 bases:

>100_bases
TCTGGCACGCAGGCTTTACGCTAATATCACCACGCACAGTATATTGACAATCTTCAATATACTGCTATACTACCTGTGTC
GAAGATTTCGGGGAGGTAGT

Downstream 100 bases:

>100_bases
TCTGGATGGGGTGATGGAGAGGCGTTTTTTTGTGGTTTGTATATCGATGATCTTCGATATAATAGCTGAAAGGAAGACAC
GTCATGACTCTCCCAATCGC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MNAQPTDQETPAVQVMSCCAPAITVTLSDAEAAQLADALSLLAHPIRLRLLAILARNAGHVCVCDLEAALPVKQPTVSHH
LRLLRDGGLIEGERRGQWIYYAIRQDALATVRLLIDQFFASLTPDKA

Sequences:

>Translated_127_residues
MNAQPTDQETPAVQVMSCCAPAITVTLSDAEAAQLADALSLLAHPIRLRLLAILARNAGHVCVCDLEAALPVKQPTVSHH
LRLLRDGGLIEGERRGQWIYYAIRQDALATVRLLIDQFFASLTPDKA
>Mature_127_residues
MNAQPTDQETPAVQVMSCCAPAITVTLSDAEAAQLADALSLLAHPIRLRLLAILARNAGHVCVCDLEAALPVKQPTVSHH
LRLLRDGGLIEGERRGQWIYYAIRQDALATVRLLIDQFFASLTPDKA

Specific function: Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ziaA-mediated efflux of excess zinc into the periplasm [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13795; Mature: 13795

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAQPTDQETPAVQVMSCCAPAITVTLSDAEAAQLADALSLLAHPIRLRLLAILARNAGH
CCCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VCVCDLEAALPVKQPTVSHHLRLLRDGGLIEGERRGQWIYYAIRQDALATVRLLIDQFFA
EEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
SLTPDKA
HCCCCCC
>Mature Secondary Structure
MNAQPTDQETPAVQVMSCCAPAITVTLSDAEAAQLADALSLLAHPIRLRLLAILARNAGH
CCCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VCVCDLEAALPVKQPTVSHHLRLLRDGGLIEGERRGQWIYYAIRQDALATVRLLIDQFFA
EEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
SLTPDKA
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9724772 [H]