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The map label for this gene is ygbD [C]

Identifier: 222527086

GI number: 222527086

Start: 4811681

End: 4813021

Strand: Reverse

Name: ygbD [C]

Synonym: Chy400_3865

Alternate gene names: 222527086

Gene position: 4813021-4811681 (Counterclockwise)

Preceding gene: 222527087

Following gene: 222527082

Centisome position: 91.35

GC content: 61.07

Gene sequence:

>1341_bases
ATGGGGCGACGGGTGGTCGTGATCGGTGGTGGGGCGGCAGGCATGAGTGCAGCGGCCAAAGCCCGCCGCACCGATCCAAC
GCTTGAAATTGTGGTGTATGAGCGGTCGGGATTTGTGAGCTACGGTGCCTGTGGCTTTCCGTATGCCATTAAGGGCGAGA
TTGCGCGGGTTGAAGACCTGATCGTGCGCACGCCAGAGCAATTCGCCAGGCAAGGCATTCAAGCCCTGGTGCGACACGAA
GTGCTGGAGATTGATCCAGACCGGCAGACGGTGCGTGTGCGGGATTTGCGCAGCGAACGCGAGTTTGTTGACCATTGGGA
CGACCTGGTGGTGACGACAGGTGGGCAACCTGGTCGTCCGCCTTTACCGGGGATTGATCTGGCGGGTGTCTTTGCGCTGC
GTCAGGTTGAGGATGCGCTGGCGATCAAGGAATGGTTGAACGAACAACGACCGCGTAGCGGCGTGATTATCGGGGGTGGG
TATATCGGGTTAGAGATGGCTGAAGCGCTGGCCGCGCATGGCATATCGCTCACCCTGATCGAACGGTTGCCCCAGGTGCT
ACCGGCTATGGATGCCGATCTGGCGAGCCAGATCGAGGCAGAGCTGATCCGACAGGGGGTGGATCTGCGTTTGAACCAGA
CGGTGCAGGGGCTTGTCGGCGATGAACGGGTACGTGCGGTTATCGCTGAAGGGCAGACTATCCCGGCAGAGATTGTGATT
CTCGCCGTTGGGGTCAAACCAGGTGTTGCGCTTGCCCAGGCTGCCGGGATCGGGTTGGGGCCGACCGGAGCGATTGCCGT
CGATGATCATCAGCGGACCAACCTTCCGCAGGTGTGGGCAGCGGGTGATGTGGCTGAAGCGTGGCATCGGGTGATTCAGA
AACCGGTATGGATGCCGCTCGGTACTACGGCCAACAAGCAGGGGCGTGTGGCCGGTGAGAATCTGGCGGGTGGCGATGCC
CGGTTTGGTGGTATTGTCGGTACGGTAGCGGTCAAGGTCTTTGCGCTAGAGGCCGCAATGAGCGGGCTGTCACTGGCACG
GGCGCAGGCCGAGGGGTTTGCCGCCGAGGCGGTGCAGGCCACAGCTGGCTCACGGGCACACTATATGCCGGGCCATCAGC
CGATTACCGTTTCGCTGGTATTTGATCGGAATACACGCCGTTTGCTAGGCGGTCAGATGGTTGGTCGCGAAGGTGTGGCG
AAGCGGATTGACACGATTGCGGCTGCGCTGCAAGCCGGCTGGACGATTGATGATCTGGCTGAGCTTGATCTGAGCTATGC
GCCGCCATTTGCGCCGGTTTGGGATCCGATCCTGGTGGCGGCTAATCTGGCACGGAAGTAA

Upstream 100 bases:

>100_bases
GGGTGCTGGCGCTGGTGGGGAGCGGAAACGTAACCTGAGCGGTGACAAGTGCATCTTTATAGTCAAAGGTGTTTTCTGTT
CAGCAACCCGGAGGATTTGA

Downstream 100 bases:

>100_bases
TCCGGCGGTGGCGGGGATGGCTGCGCGCGGGCTGGAAACCCGCCATTACTGACCGACCCCATGATCGTGACAGGCAAACA
CGGCATCCCTCAAACCAACA

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MGRRVVVIGGGAAGMSAAAKARRTDPTLEIVVYERSGFVSYGACGFPYAIKGEIARVEDLIVRTPEQFARQGIQALVRHE
VLEIDPDRQTVRVRDLRSEREFVDHWDDLVVTTGGQPGRPPLPGIDLAGVFALRQVEDALAIKEWLNEQRPRSGVIIGGG
YIGLEMAEALAAHGISLTLIERLPQVLPAMDADLASQIEAELIRQGVDLRLNQTVQGLVGDERVRAVIAEGQTIPAEIVI
LAVGVKPGVALAQAAGIGLGPTGAIAVDDHQRTNLPQVWAAGDVAEAWHRVIQKPVWMPLGTTANKQGRVAGENLAGGDA
RFGGIVGTVAVKVFALEAAMSGLSLARAQAEGFAAEAVQATAGSRAHYMPGHQPITVSLVFDRNTRRLLGGQMVGREGVA
KRIDTIAAALQAGWTIDDLAELDLSYAPPFAPVWDPILVAANLARK

Sequences:

>Translated_446_residues
MGRRVVVIGGGAAGMSAAAKARRTDPTLEIVVYERSGFVSYGACGFPYAIKGEIARVEDLIVRTPEQFARQGIQALVRHE
VLEIDPDRQTVRVRDLRSEREFVDHWDDLVVTTGGQPGRPPLPGIDLAGVFALRQVEDALAIKEWLNEQRPRSGVIIGGG
YIGLEMAEALAAHGISLTLIERLPQVLPAMDADLASQIEAELIRQGVDLRLNQTVQGLVGDERVRAVIAEGQTIPAEIVI
LAVGVKPGVALAQAAGIGLGPTGAIAVDDHQRTNLPQVWAAGDVAEAWHRVIQKPVWMPLGTTANKQGRVAGENLAGGDA
RFGGIVGTVAVKVFALEAAMSGLSLARAQAEGFAAEAVQATAGSRAHYMPGHQPITVSLVFDRNTRRLLGGQMVGREGVA
KRIDTIAAALQAGWTIDDLAELDLSYAPPFAPVWDPILVAANLARK
>Mature_445_residues
GRRVVVIGGGAAGMSAAAKARRTDPTLEIVVYERSGFVSYGACGFPYAIKGEIARVEDLIVRTPEQFARQGIQALVRHEV
LEIDPDRQTVRVRDLRSEREFVDHWDDLVVTTGGQPGRPPLPGIDLAGVFALRQVEDALAIKEWLNEQRPRSGVIIGGGY
IGLEMAEALAAHGISLTLIERLPQVLPAMDADLASQIEAELIRQGVDLRLNQTVQGLVGDERVRAVIAEGQTIPAEIVIL
AVGVKPGVALAQAAGIGLGPTGAIAVDDHQRTNLPQVWAAGDVAEAWHRVIQKPVWMPLGTTANKQGRVAGENLAGGDAR
FGGIVGTVAVKVFALEAAMSGLSLARAQAEGFAAEAVQATAGSRAHYMPGHQPITVSLVFDRNTRRLLGGQMVGREGVAK
RIDTIAAALQAGWTIDDLAELDLSYAPPFAPVWDPILVAANLARK

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=396, Percent_Identity=27.020202020202, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI226437568, Length=396, Percent_Identity=27.020202020202, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI21389617, Length=396, Percent_Identity=27.020202020202, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1789065, Length=345, Percent_Identity=26.6666666666667, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786307, Length=328, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788892, Length=187, Percent_Identity=34.2245989304813, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789765, Length=407, Percent_Identity=23.8329238329238, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87081717, Length=334, Percent_Identity=27.8443113772455, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789915, Length=186, Percent_Identity=26.8817204301075, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=289, Percent_Identity=28.0276816608997, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24639257, Length=323, Percent_Identity=26.0061919504644, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281359715, Length=323, Percent_Identity=26.0061919504644, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281359713, Length=323, Percent_Identity=26.0061919504644, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24639250, Length=323, Percent_Identity=26.0061919504644, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI18543267, Length=323, Percent_Identity=26.0061919504644, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24639252, Length=323, Percent_Identity=26.0061919504644, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24585130, Length=333, Percent_Identity=23.4234234234234, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 47384; Mature: 47253

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRVVVIGGGAAGMSAAAKARRTDPTLEIVVYERSGFVSYGACGFPYAIKGEIARVEDL
CCCEEEEECCCCCCHHHHHHHCCCCCCEEEEEEECCCCEEECCCCCCEEECCCHHHHHHH
IVRTPEQFARQGIQALVRHEVLEIDPDRQTVRVRDLRSEREFVDHWDDLVVTTGGQPGRP
HHCCHHHHHHHHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCC
PLPGIDLAGVFALRQVEDALAIKEWLNEQRPRSGVIIGGGYIGLEMAEALAAHGISLTLI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCHHHH
ERLPQVLPAMDADLASQIEAELIRQGVDLRLNQTVQGLVGDERVRAVIAEGQTIPAEIVI
HHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHCCHHHHHHHHHCCCCCCEEEEE
LAVGVKPGVALAQAAGIGLGPTGAIAVDDHQRTNLPQVWAAGDVAEAWHRVIQKPVWMPL
EEECCCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHCCCCHHHHHHHHHCCCCCCCC
GTTANKQGRVAGENLAGGDARFGGIVGTVAVKVFALEAAMSGLSLARAQAEGFAAEAVQA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TAGSRAHYMPGHQPITVSLVFDRNTRRLLGGQMVGREGVAKRIDTIAAALQAGWTIDDLA
HCCCCCCCCCCCCCEEEEEEEECCCHHHHCCHHHCHHHHHHHHHHHHHHHHCCCCHHHHH
ELDLSYAPPFAPVWDPILVAANLARK
HCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRRVVVIGGGAAGMSAAAKARRTDPTLEIVVYERSGFVSYGACGFPYAIKGEIARVEDL
CCEEEEECCCCCCHHHHHHHCCCCCCEEEEEEECCCCEEECCCCCCEEECCCHHHHHHH
IVRTPEQFARQGIQALVRHEVLEIDPDRQTVRVRDLRSEREFVDHWDDLVVTTGGQPGRP
HHCCHHHHHHHHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCC
PLPGIDLAGVFALRQVEDALAIKEWLNEQRPRSGVIIGGGYIGLEMAEALAAHGISLTLI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCHHHH
ERLPQVLPAMDADLASQIEAELIRQGVDLRLNQTVQGLVGDERVRAVIAEGQTIPAEIVI
HHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHCCHHHHHHHHHCCCCCCEEEEE
LAVGVKPGVALAQAAGIGLGPTGAIAVDDHQRTNLPQVWAAGDVAEAWHRVIQKPVWMPL
EEECCCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHCCCCHHHHHHHHHCCCCCCCC
GTTANKQGRVAGENLAGGDARFGGIVGTVAVKVFALEAAMSGLSLARAQAEGFAAEAVQA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TAGSRAHYMPGHQPITVSLVFDRNTRRLLGGQMVGREGVAKRIDTIAAALQAGWTIDDLA
HCCCCCCCCCCCCCEEEEEEEECCCHHHHCCHHHCHHHHHHHHHHHHHHHHCCCCHHHHH
ELDLSYAPPFAPVWDPILVAANLARK
HCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA