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The map label for this gene is lacZ [C]

Identifier: 222527056

GI number: 222527056

Start: 4778585

End: 4780741

Strand: Direct

Name: lacZ [C]

Synonym: Chy400_3835

Alternate gene names: 222527056

Gene position: 4778585-4780741 (Clockwise)

Preceding gene: 222527055

Following gene: 222527058

Centisome position: 90.69

GC content: 57.21

Gene sequence:

>2157_bases
ATGTATCTCGTTACCCTGCAGGATAACTGGCAGATTCGCCCGCTGAACGAATTTTCGCACGGCATCTACCCGCGTCACGA
TAGCGAATGGCTACCAGCCATCGTTCCGGCTCACTGGCAACAATTACCAGGGCTGGAAACCCACAGTGGCAAGGTGGTCT
ACCGCTGTCGCTTCCCCAACCCGCCTGAAGTGAGTCGTGTCTCTGGTGAACGGCGCTGGTTGCGCATTAACGGCGCGTTC
TACTATCGGCACACCTATCTTAATGGGATCGATCTGGGTGCCCACGAGGGCTATTTCGAGCCGACTGAGCACGACATCAC
TACCTTGCTGCGTGCCCAGAACACCTTAATCATCGAACTCGATTGTCCTGATGAACACAACAAAATCGGCAAACGGATGA
TTACGGGGGTCTTTTCGCATTGGGATTGTTTCGACCCCCAGGCTAATCCGGGAGGTATCTGGTTGCCGGTCGAGATGCAC
TACAGTGGCCCTGTGCGCCTCCACCAGGCTCGCCTGCGCACCGAACATTGTGACGCCCGGCTGGCGCAGTTGCGTTTTGC
CCTTGACCTCGACGCTGCCCAGGCCGTGACCATCCGCAGCGAATTGATCTTCGCGCCGCTGACATTCCACGGTGAAACAC
AGGTCTTTACCGTTCAGCGTCGCTTGCGGGGCGGCAAACAAACCGTGCAGGGTCTTTTAAAATTGCGCGAACCGCGTCGT
TGGTGGACGCATGATTTGGGCCGCCCCGATCTCTATCAGGTGACCGTGCGCATCTGGCTTGATGACTGCCTGAGCGATGA
GCAATCATTTGCGTATGGTGTGCGCACCTTTGAATTGCGCGACTGGATTCCCCATCTGAACGGTGAGCGGTTTCTGGCCA
AGGGAAACAACTACCCGCCCGGCGATATGCGGATTGCGACGATGAATCGCGAGCGTGCTGAGCGCGATCTATCCCTGGCA
CGCGATTGCCACATGAACATGCTCCGCGTTCATGCCCACATCGACCATCCGGCCTTCTACGATGCGGCTGATGCCGCCGG
GATACTGCTCTGGCAAGATTTTCCGCTCCAGTGGCTGTATCGACCAGACGTGCTACCGGCAGCCCGTCACCAGGCCCGGG
CTATGGTACGCTTGCTCGGCAATCATCCCAGTATTGCGATCTGGTGCATGCACAACGAAGCGATCCACCTCGAAGATACT
GCCGATGAATCGCTCCCGGCGCGGCTACGTACCTATCAATCGGCATTTGTCTTTAGCTGGAACCGTGATGTGATGGATGT
GCAGTTGAAGCAGATCGTCGAAGAAGAAGACCCAACCCGACCGGTAGTGCGTTCGTCGGGTGAGCCAGATGTTCCCTACG
TGCGTACCGGCACCGACGCCCATGCCTACTTCGGCTGGTATCGCACCTACGGTTCGCTGGCCGATGGAGAAGCGGTACGG
GCGCGTTTTCCGGGAAACCTGCGCTTCGTGACCGAGTTCGGTGCGCAGAGTTTTCCCAACCTCGAGAGCAGCCTGCGCTT
TATGCCTGATCCGCTCGACGATGCTGCGATCAATCGCCTGATAGAACGGCATGGTCTACAGGCAGAGATCATGTCGGCCT
GGTATCCCTGGCGGCAGGCAACATCACTGGCCGAAGTGATCGAGATGTCACAGAACTATCAGGCCGAACTGAATCGCTTC
TACATTGATCGCCTTCGCTACCATAAATATCGTCCAACCGGTGGTATCATCGCCTTTCTCTTCGTCGATCCGTACCCCGC
TGTTTTGTGGAGCGTGATCGACTACTGGCGGGTGCCCAAACGTTCGTACTACGCTCTGCGCGACTGTTTTCGCCCACAAT
ATGTCTTTACCCTGATCGAGCCGCGCACATTTACCATTGGCGAAGCAATTGATCTTCCTATCTACGCCGTCAACGATGCC
CGCGAGCCGCTGGTTGGTGCGCAACTGACCATCAGCCTGTACGACCCCACCGATACCGAACTGGCTACCGTTGTTCGCTA
CCTCGATCTCCCTGCCGACTCTCTGGCAACCGAAGTTGATCGCCTGCGCCTCACACCAATCCGTGCCGGCGAGTACACCA
TTGTGCTGCGCCTGATCGGAGCCGGGCCGGAGTTTACCAATCGCTATCGGTTAACTGCGGAAGAGAAGACACCCTAA

Upstream 100 bases:

>100_bases
GCTCGGTCATCGGCCAGAGCTGCGGCGGCAGCGGATTGTGCTCTATCAGCAGGTGTTGTATACCTTGAATAATACCCGGT
AGTCATTGCCGAATTAGCAT

Downstream 100 bases:

>100_bases
ACGTGATCTGGACGTTGAAGTCTACACGCCCTTGCAGCTCCATATGCGGGGACACGGATAGACGCGGATTAGGCGGATGC
ACGCGGATAGGTTGTCTGTA

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: Glycoside Hydrolase Family Protein; Beta-Galactosidase; Beta-Mannosidase Protein; Glycoside Hydrolase; Glycosyl Hydrolase; Mannosidase; Coagulation Factor 5/8 Type Domain Protein; Hydrolase; Glycoside Hydrolase Family 2 TIM Barrel; Beta-Glucuronidase; Beta-Galactosidase/Beta- Glucuronidase Family Protein; O-Glycosyl Hydrolase; Beta-Mannosidase Man2A; Exo-Beta-D-Glucosaminidase; Beta-Galactosidase Bgl2B; Beta-Galactosidase/Beta; Beta-Galactosidase Bgl2A; Mannosylglycoprotein Endo-Beta-Mannosidase; BETA-Mannosidase Protein; Beta-Galactosidase/Beta-Glucuronidase

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MYLVTLQDNWQIRPLNEFSHGIYPRHDSEWLPAIVPAHWQQLPGLETHSGKVVYRCRFPNPPEVSRVSGERRWLRINGAF
YYRHTYLNGIDLGAHEGYFEPTEHDITTLLRAQNTLIIELDCPDEHNKIGKRMITGVFSHWDCFDPQANPGGIWLPVEMH
YSGPVRLHQARLRTEHCDARLAQLRFALDLDAAQAVTIRSELIFAPLTFHGETQVFTVQRRLRGGKQTVQGLLKLREPRR
WWTHDLGRPDLYQVTVRIWLDDCLSDEQSFAYGVRTFELRDWIPHLNGERFLAKGNNYPPGDMRIATMNRERAERDLSLA
RDCHMNMLRVHAHIDHPAFYDAADAAGILLWQDFPLQWLYRPDVLPAARHQARAMVRLLGNHPSIAIWCMHNEAIHLEDT
ADESLPARLRTYQSAFVFSWNRDVMDVQLKQIVEEEDPTRPVVRSSGEPDVPYVRTGTDAHAYFGWYRTYGSLADGEAVR
ARFPGNLRFVTEFGAQSFPNLESSLRFMPDPLDDAAINRLIERHGLQAEIMSAWYPWRQATSLAEVIEMSQNYQAELNRF
YIDRLRYHKYRPTGGIIAFLFVDPYPAVLWSVIDYWRVPKRSYYALRDCFRPQYVFTLIEPRTFTIGEAIDLPIYAVNDA
REPLVGAQLTISLYDPTDTELATVVRYLDLPADSLATEVDRLRLTPIRAGEYTIVLRLIGAGPEFTNRYRLTAEEKTP

Sequences:

>Translated_718_residues
MYLVTLQDNWQIRPLNEFSHGIYPRHDSEWLPAIVPAHWQQLPGLETHSGKVVYRCRFPNPPEVSRVSGERRWLRINGAF
YYRHTYLNGIDLGAHEGYFEPTEHDITTLLRAQNTLIIELDCPDEHNKIGKRMITGVFSHWDCFDPQANPGGIWLPVEMH
YSGPVRLHQARLRTEHCDARLAQLRFALDLDAAQAVTIRSELIFAPLTFHGETQVFTVQRRLRGGKQTVQGLLKLREPRR
WWTHDLGRPDLYQVTVRIWLDDCLSDEQSFAYGVRTFELRDWIPHLNGERFLAKGNNYPPGDMRIATMNRERAERDLSLA
RDCHMNMLRVHAHIDHPAFYDAADAAGILLWQDFPLQWLYRPDVLPAARHQARAMVRLLGNHPSIAIWCMHNEAIHLEDT
ADESLPARLRTYQSAFVFSWNRDVMDVQLKQIVEEEDPTRPVVRSSGEPDVPYVRTGTDAHAYFGWYRTYGSLADGEAVR
ARFPGNLRFVTEFGAQSFPNLESSLRFMPDPLDDAAINRLIERHGLQAEIMSAWYPWRQATSLAEVIEMSQNYQAELNRF
YIDRLRYHKYRPTGGIIAFLFVDPYPAVLWSVIDYWRVPKRSYYALRDCFRPQYVFTLIEPRTFTIGEAIDLPIYAVNDA
REPLVGAQLTISLYDPTDTELATVVRYLDLPADSLATEVDRLRLTPIRAGEYTIVLRLIGAGPEFTNRYRLTAEEKTP
>Mature_718_residues
MYLVTLQDNWQIRPLNEFSHGIYPRHDSEWLPAIVPAHWQQLPGLETHSGKVVYRCRFPNPPEVSRVSGERRWLRINGAF
YYRHTYLNGIDLGAHEGYFEPTEHDITTLLRAQNTLIIELDCPDEHNKIGKRMITGVFSHWDCFDPQANPGGIWLPVEMH
YSGPVRLHQARLRTEHCDARLAQLRFALDLDAAQAVTIRSELIFAPLTFHGETQVFTVQRRLRGGKQTVQGLLKLREPRR
WWTHDLGRPDLYQVTVRIWLDDCLSDEQSFAYGVRTFELRDWIPHLNGERFLAKGNNYPPGDMRIATMNRERAERDLSLA
RDCHMNMLRVHAHIDHPAFYDAADAAGILLWQDFPLQWLYRPDVLPAARHQARAMVRLLGNHPSIAIWCMHNEAIHLEDT
ADESLPARLRTYQSAFVFSWNRDVMDVQLKQIVEEEDPTRPVVRSSGEPDVPYVRTGTDAHAYFGWYRTYGSLADGEAVR
ARFPGNLRFVTEFGAQSFPNLESSLRFMPDPLDDAAINRLIERHGLQAEIMSAWYPWRQATSLAEVIEMSQNYQAELNRF
YIDRLRYHKYRPTGGIIAFLFVDPYPAVLWSVIDYWRVPKRSYYALRDCFRPQYVFTLIEPRTFTIGEAIDLPIYAVNDA
REPLVGAQLTISLYDPTDTELATVVRYLDLPADSLATEVDRLRLTPIRAGEYTIVLRLIGAGPEFTNRYRLTAEEKTP

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI84798622, Length=659, Percent_Identity=22.3065250379363, Blast_Score=91, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24643838, Length=627, Percent_Identity=23.7639553429027, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24643840, Length=610, Percent_Identity=23.6065573770492, Blast_Score=93, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.23

Molecular weight: Translated: 83186; Mature: 83186

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLVTLQDNWQIRPLNEFSHGIYPRHDSEWLPAIVPAHWQQLPGLETHSGKVVYRCRFPN
CEEEEEECCCEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEECCC
PPEVSRVSGERRWLRINGAFYYRHTYLNGIDLGAHEGYFEPTEHDITTLLRAQNTLIIEL
CCCHHHCCCCCEEEEECCEEEEEEEEECCEECCCCCCCCCCCHHHHHHHHHCCCEEEEEE
DCPDEHNKIGKRMITGVFSHWDCFDPQANPGGIWLPVEMHYSGPVRLHQARLRTEHCDAR
ECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCEEHHHHHHHHHHHHH
LAQLRFALDLDAAQAVTIRSELIFAPLTFHGETQVFTVQRRLRGGKQTVQGLLKLREPRR
HHHHHEEEECCCHHEEEEEEEEEEEEEEECCCCEEEEEHHHHCCCHHHHHHHHHHCCCCH
WWTHDLGRPDLYQVTVRIWLDDCLSDEQSFAYGVRTFELRDWIPHLNGERFLAKGNNYPP
HHHHCCCCCCCEEEEEEEEEHHHCCCCCHHHHCEEEEEHHHHCCCCCCCEEEECCCCCCC
GDMRIATMNRERAERDLSLARDCHMNMLRVHAHIDHPAFYDAADAAGILLWQDFPLQWLY
CCEEEEECCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEE
RPDVLPAARHQARAMVRLLGNHPSIAIWCMHNEAIHLEDTADESLPARLRTYQSAFVFSW
CCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEECCCCCCCCHHHHHHHHEEEEEEE
NRDVMDVQLKQIVEEEDPTRPVVRSSGEPDVPYVRTGTDAHAYFGWYRTYGSLADGEAVR
CCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCEEE
ARFPGNLRFVTEFGAQSFPNLESSLRFMPDPLDDAAINRLIERHGLQAEIMSAWYPWRQA
EECCCCEEEEEECCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCHHHH
TSLAEVIEMSQNYQAELNRFYIDRLRYHKYRPTGGIIAFLFVDPYPAVLWSVIDYWRVPK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCHHHHHHHHHHHHCCCC
RSYYALRDCFRPQYVFTLIEPRTFTIGEAIDLPIYAVNDAREPLVGAQLTISLYDPTDTE
HHHHHHHHHCCCCEEEEEECCCEEECCCEECCCEEEECCCCCCCCCEEEEEEEECCCCHH
LATVVRYLDLPADSLATEVDRLRLTPIRAGEYTIVLRLIGAGPEFTNRYRLTAEEKTP
HHHHHHHHCCCHHHHHHHHHHEEEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MYLVTLQDNWQIRPLNEFSHGIYPRHDSEWLPAIVPAHWQQLPGLETHSGKVVYRCRFPN
CEEEEEECCCEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEECCC
PPEVSRVSGERRWLRINGAFYYRHTYLNGIDLGAHEGYFEPTEHDITTLLRAQNTLIIEL
CCCHHHCCCCCEEEEECCEEEEEEEEECCEECCCCCCCCCCCHHHHHHHHHCCCEEEEEE
DCPDEHNKIGKRMITGVFSHWDCFDPQANPGGIWLPVEMHYSGPVRLHQARLRTEHCDAR
ECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCEEHHHHHHHHHHHHH
LAQLRFALDLDAAQAVTIRSELIFAPLTFHGETQVFTVQRRLRGGKQTVQGLLKLREPRR
HHHHHEEEECCCHHEEEEEEEEEEEEEEECCCCEEEEEHHHHCCCHHHHHHHHHHCCCCH
WWTHDLGRPDLYQVTVRIWLDDCLSDEQSFAYGVRTFELRDWIPHLNGERFLAKGNNYPP
HHHHCCCCCCCEEEEEEEEEHHHCCCCCHHHHCEEEEEHHHHCCCCCCCEEEECCCCCCC
GDMRIATMNRERAERDLSLARDCHMNMLRVHAHIDHPAFYDAADAAGILLWQDFPLQWLY
CCEEEEECCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEE
RPDVLPAARHQARAMVRLLGNHPSIAIWCMHNEAIHLEDTADESLPARLRTYQSAFVFSW
CCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEECCCCCCCCHHHHHHHHEEEEEEE
NRDVMDVQLKQIVEEEDPTRPVVRSSGEPDVPYVRTGTDAHAYFGWYRTYGSLADGEAVR
CCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCEEE
ARFPGNLRFVTEFGAQSFPNLESSLRFMPDPLDDAAINRLIERHGLQAEIMSAWYPWRQA
EECCCCEEEEEECCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCHHHH
TSLAEVIEMSQNYQAELNRFYIDRLRYHKYRPTGGIIAFLFVDPYPAVLWSVIDYWRVPK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCHHHHHHHHHHHHCCCC
RSYYALRDCFRPQYVFTLIEPRTFTIGEAIDLPIYAVNDAREPLVGAQLTISLYDPTDTE
HHHHHHHHHCCCCEEEEEECCCEEECCCEECCCEEEECCCCCCCCCEEEEEEEECCCCHH
LATVVRYLDLPADSLATEVDRLRLTPIRAGEYTIVLRLIGAGPEFTNRYRLTAEEKTP
HHHHHHHHCCCHHHHHHHHHHEEEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Glycosylases; Glycosidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA