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The map label for this gene is zraS [C]

Identifier: 222526995

GI number: 222526995

Start: 4693679

End: 4696297

Strand: Direct

Name: zraS [C]

Synonym: Chy400_3773

Alternate gene names: 222526995

Gene position: 4693679-4696297 (Clockwise)

Preceding gene: 222526994

Following gene: 222526996

Centisome position: 89.08

GC content: 54.79

Gene sequence:

>2619_bases
ATGGCTGCCGTTTCCGATCCACCTTCACCTTCCGCGAAGACCTACCTTCGCGATCACTCAATCCAGCTCCTGCGCGATCT
TATCTGGATAAGTCTGATAGCCGCACTAGCCTACACCATTTTCAGCCCGATTGACCCATCATTGATGCCACAGCGGATGG
TTGTGGTGGTACCGCTGATCCTGGGCTTGTTGGGGGCCTGGTGGCTTATCCAACGCCAATACCTGCGACTGGCAAGTATC
CTGGTGATTAGCATACTCTGGCTGGTACTGGCATTCTCGGCGTTCATCAGTGGTGGTCTGCAAGCACCGGCGTTTGCCGG
CATCCCACTGGTGGTGATCATGGCCGGGATTTTACTCGGCTGGTGTGGTGCTCTGACTATTGCGCTACTTTCAATCGGTA
CCGGTGCCCTCTTCGTGCGCTTTGCCGATCTCCTGCCACCACCACCGGTATTCCATTCTCCTCTGGTCTGGTTTATTACC
TATACTCTCTACCTACTGCTGGCAACCCGCATGATTAGCCAGATTGTTACTCACTTCTATCAGTCTATGCAAGAGACGGA
TAAAGAACTGAGCGAACGAAAGGCTGTCGAGCAGCAATTGCGTCTATCAGAAGAAAAATTTGCCCGCTTGTTTGATTCAG
CACCGTTTCCGATGCTTATTGTACGGCTGGATGACAATCTGATCCTGAATGCTAACGCCGCTTGCCGCGAATTTTTTGAG
TTAAGTAGTGATCAAATCATTAAGCAACACATTAACCGCCTCGATTGGTCACAATTACCCAGCCGCTGGCAGGCTATCGC
CGATACATTACGCCAGGAAGGAACGGTTAGTGAGGTTGAATTCAGTTTTTGTCGGCGCGATGGCTCAACCTGCTACACCC
AATTGACTGCCGAGATTGTCGAATTACAGGAAGGGTTGTGTGCGGTCGTCGCATTTCAAGACGTAACACCGTTGCGTCGT
GCCAATGAACGACTGATTGAGCTGGCAAGCCAGCAAGAACAACTGGCAACGCTGGCACGAGAAGCACTCGCGAGTACCGA
TTTGAATACTCTCTTTGCGGTGGCAGCCGAACAAATGGTACAGGCGTTGCCGATAAGCGGTGTTGAATTCATCGATGTCG
ATATTGATGGAAACATCACCATCCGCAACACCTGGGGCGAGGTACCCGCCCAACCTGTACCGGAGAGATTCTTTCAAGGG
CTGACGGTGGATCATCCGGGCTGGAGTAATCTGCCGGCTCCATTAGCGGAACGGGCTGCCGATGTCGCGCAGCACGGTGC
TGTGATGCTGATCGGCGGGCACCAGCGTCTCTTTGGTGCTCTGCTGGTGTACACATCGACGGCGCTTGATGCTGAGGCTA
TCTTCTTCTTACGCAGCGTGGCAAATGTGCTGGCAGTTGCCCTGGAGCGCTTCCACGCCGAACAGGAGCGACGTCAGATC
GAGAGCCAGATGCTTCAGACGCAAAAGCTGGAAAGTCTAGGCTTGCTGGCCGGTGGGATTGCCCACGATTTCAACAATCT
GCTAACCGGCATTATGGGACATACCAGTCTGGCCTTGATCGATCTCCCTCCGAACCACGAGCTACAACCGCATCTGGCGG
CCATCGACCAGGCTGCACAGCGAGCGGCTGAGCTGTGTCATCAATTACTGGTCTATGCTGGACGCGGCCAACGCTCGCTT
GAAGTGGTAGACCTCTCGAATCTGGTGCGCGAAATGGGGAATATTCTACGTTTACCGACAAACCGGAGTCATCAGGTCGC
TATTCACTACGATTTGGACACCAATCTCCCACCGATTTTGGTTGAGGCGAGTCAGATTCGGCAGGTTGTGCTTAATCTGC
TCACCAATGCGATTGAGGCGATTGGTGAGCGTAGTGGGTCGGTTACGCTGCGGACTGGGGTCGCGAGTCTCAGTGCAGCA
GACCTGCGCCGGCTGCGGCTAATGCCGACAATTCCACCGGGTGACTACGTAACGCTAACGGTGAGCGATACCGGCATAGG
TATGGACGAAGCAACCCTGCGGCGCATTTTCGATCCCTTCTTCAGTACCAAACCGAAGGGCCATGGTCTTGGCCTTGCGG
CTGTACAGGGAATCGTCCGACGCCACAATGGCGCGATTCGGGTTGAGAGTACGCCAGGATTGGGGTCAACCTTTACCGTG
TATCTCCCGGCAGCCCACCAGGCTACCCCGGTAGTCACGACCAATGCAACGATGCCCATTGTACTGCGCGGCACCGCGCT
GATCGTCGATGACGATCCGGCAATACGGGCCACGCTGAACCGCATCCTGGAACGGGCCGGCATGGTCACCACGGAGGCTG
CCAATGGTCAGGCAGCGCTGAGTATGCTGACCGAGTCGGCGCTGAGCATTGACATTGCCCTGGTTGATCTGGCAATGCCG
GGTATGAATGGGCTGGAACTGCTGGCAGCGATTCGTCGCCGTATGCCCCAATTACCGGTCTTGCTGATGAGCGGGAATGC
CGGCGAAGTGACGAAAGATAACTTGCCTCTGGATCACTACACCGATTTTTTACCCAAACCGTACCGGTCACGCGATCTGC
TGGAAAAAATGAGCACGTTGTTACAGCGAGTAGCGGCATTGCGTATCCACGGTAGTTGA

Upstream 100 bases:

>100_bases
TCTGAACAAGACACGTAGGTTACCCAACCGATCACCACTGAAGGTGGATCGACGGCAGTCTGCATCACGATATTCCGCTG
CTTCATGCAGGAGGGTATTC

Downstream 100 bases:

>100_bases
GGTCTGGGCAAACGTGGCTTCCGCGTGCAGAGGATGGTGCCAGGCACCATGCGCGCCGGAGGCGTGCGCTCCCTGAGGAG
ATAGGAGAGGTGTCGTGCGC

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 872; Mature: 871

Protein sequence:

>872_residues
MAAVSDPPSPSAKTYLRDHSIQLLRDLIWISLIAALAYTIFSPIDPSLMPQRMVVVVPLILGLLGAWWLIQRQYLRLASI
LVISILWLVLAFSAFISGGLQAPAFAGIPLVVIMAGILLGWCGALTIALLSIGTGALFVRFADLLPPPPVFHSPLVWFIT
YTLYLLLATRMISQIVTHFYQSMQETDKELSERKAVEQQLRLSEEKFARLFDSAPFPMLIVRLDDNLILNANAACREFFE
LSSDQIIKQHINRLDWSQLPSRWQAIADTLRQEGTVSEVEFSFCRRDGSTCYTQLTAEIVELQEGLCAVVAFQDVTPLRR
ANERLIELASQQEQLATLAREALASTDLNTLFAVAAEQMVQALPISGVEFIDVDIDGNITIRNTWGEVPAQPVPERFFQG
LTVDHPGWSNLPAPLAERAADVAQHGAVMLIGGHQRLFGALLVYTSTALDAEAIFFLRSVANVLAVALERFHAEQERRQI
ESQMLQTQKLESLGLLAGGIAHDFNNLLTGIMGHTSLALIDLPPNHELQPHLAAIDQAAQRAAELCHQLLVYAGRGQRSL
EVVDLSNLVREMGNILRLPTNRSHQVAIHYDLDTNLPPILVEASQIRQVVLNLLTNAIEAIGERSGSVTLRTGVASLSAA
DLRRLRLMPTIPPGDYVTLTVSDTGIGMDEATLRRIFDPFFSTKPKGHGLGLAAVQGIVRRHNGAIRVESTPGLGSTFTV
YLPAAHQATPVVTTNATMPIVLRGTALIVDDDPAIRATLNRILERAGMVTTEAANGQAALSMLTESALSIDIALVDLAMP
GMNGLELLAAIRRRMPQLPVLLMSGNAGEVTKDNLPLDHYTDFLPKPYRSRDLLEKMSTLLQRVAALRIHGS

Sequences:

>Translated_872_residues
MAAVSDPPSPSAKTYLRDHSIQLLRDLIWISLIAALAYTIFSPIDPSLMPQRMVVVVPLILGLLGAWWLIQRQYLRLASI
LVISILWLVLAFSAFISGGLQAPAFAGIPLVVIMAGILLGWCGALTIALLSIGTGALFVRFADLLPPPPVFHSPLVWFIT
YTLYLLLATRMISQIVTHFYQSMQETDKELSERKAVEQQLRLSEEKFARLFDSAPFPMLIVRLDDNLILNANAACREFFE
LSSDQIIKQHINRLDWSQLPSRWQAIADTLRQEGTVSEVEFSFCRRDGSTCYTQLTAEIVELQEGLCAVVAFQDVTPLRR
ANERLIELASQQEQLATLAREALASTDLNTLFAVAAEQMVQALPISGVEFIDVDIDGNITIRNTWGEVPAQPVPERFFQG
LTVDHPGWSNLPAPLAERAADVAQHGAVMLIGGHQRLFGALLVYTSTALDAEAIFFLRSVANVLAVALERFHAEQERRQI
ESQMLQTQKLESLGLLAGGIAHDFNNLLTGIMGHTSLALIDLPPNHELQPHLAAIDQAAQRAAELCHQLLVYAGRGQRSL
EVVDLSNLVREMGNILRLPTNRSHQVAIHYDLDTNLPPILVEASQIRQVVLNLLTNAIEAIGERSGSVTLRTGVASLSAA
DLRRLRLMPTIPPGDYVTLTVSDTGIGMDEATLRRIFDPFFSTKPKGHGLGLAAVQGIVRRHNGAIRVESTPGLGSTFTV
YLPAAHQATPVVTTNATMPIVLRGTALIVDDDPAIRATLNRILERAGMVTTEAANGQAALSMLTESALSIDIALVDLAMP
GMNGLELLAAIRRRMPQLPVLLMSGNAGEVTKDNLPLDHYTDFLPKPYRSRDLLEKMSTLLQRVAALRIHGS
>Mature_871_residues
AAVSDPPSPSAKTYLRDHSIQLLRDLIWISLIAALAYTIFSPIDPSLMPQRMVVVVPLILGLLGAWWLIQRQYLRLASIL
VISILWLVLAFSAFISGGLQAPAFAGIPLVVIMAGILLGWCGALTIALLSIGTGALFVRFADLLPPPPVFHSPLVWFITY
TLYLLLATRMISQIVTHFYQSMQETDKELSERKAVEQQLRLSEEKFARLFDSAPFPMLIVRLDDNLILNANAACREFFEL
SSDQIIKQHINRLDWSQLPSRWQAIADTLRQEGTVSEVEFSFCRRDGSTCYTQLTAEIVELQEGLCAVVAFQDVTPLRRA
NERLIELASQQEQLATLAREALASTDLNTLFAVAAEQMVQALPISGVEFIDVDIDGNITIRNTWGEVPAQPVPERFFQGL
TVDHPGWSNLPAPLAERAADVAQHGAVMLIGGHQRLFGALLVYTSTALDAEAIFFLRSVANVLAVALERFHAEQERRQIE
SQMLQTQKLESLGLLAGGIAHDFNNLLTGIMGHTSLALIDLPPNHELQPHLAAIDQAAQRAAELCHQLLVYAGRGQRSLE
VVDLSNLVREMGNILRLPTNRSHQVAIHYDLDTNLPPILVEASQIRQVVLNLLTNAIEAIGERSGSVTLRTGVASLSAAD
LRRLRLMPTIPPGDYVTLTVSDTGIGMDEATLRRIFDPFFSTKPKGHGLGLAAVQGIVRRHNGAIRVESTPGLGSTFTVY
LPAAHQATPVVTTNATMPIVLRGTALIVDDDPAIRATLNRILERAGMVTTEAANGQAALSMLTESALSIDIALVDLAMPG
MNGLELLAAIRRRMPQLPVLLMSGNAGEVTKDNLPLDHYTDFLPKPYRSRDLLEKMSTLLQRVAALRIHGS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=305, Percent_Identity=30.8196721311475, Blast_Score=125, Evalue=2e-29,
Organism=Escherichia coli, GI1788549, Length=259, Percent_Identity=33.2046332046332, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI48994928, Length=373, Percent_Identity=24.6648793565684, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=28.3898305084746, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1790300, Length=285, Percent_Identity=28.4210526315789, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=381, Percent_Identity=25.9842519685039, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693157, Length=310, Percent_Identity=25.1612903225806, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790299, Length=106, Percent_Identity=38.6792452830189, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 95601; Mature: 95470

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVSDPPSPSAKTYLRDHSIQLLRDLIWISLIAALAYTIFSPIDPSLMPQRMVVVVPLI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LGLLGAWWLIQRQYLRLASILVISILWLVLAFSAFISGGLQAPAFAGIPLVVIMAGILLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
WCGALTIALLSIGTGALFVRFADLLPPPPVFHSPLVWFITYTLYLLLATRMISQIVTHFY
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSMQETDKELSERKAVEQQLRLSEEKFARLFDSAPFPMLIVRLDDNLILNANAACREFFE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCEEECCCHHHHHHHH
LSSDQIIKQHINRLDWSQLPSRWQAIADTLRQEGTVSEVEFSFCRRDGSTCYTQLTAEIV
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
ELQEGLCAVVAFQDVTPLRRANERLIELASQQEQLATLAREALASTDLNTLFAVAAEQMV
HHHCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QALPISGVEFIDVDIDGNITIRNTWGEVPAQPVPERFFQGLTVDHPGWSNLPAPLAERAA
HHCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHH
DVAQHGAVMLIGGHQRLFGALLVYTSTALDAEAIFFLRSVANVLAVALERFHAEQERRQI
HHHHCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESQMLQTQKLESLGLLAGGIAHDFNNLLTGIMGHTSLALIDLPPNHELQPHLAAIDQAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHH
RAAELCHQLLVYAGRGQRSLEVVDLSNLVREMGNILRLPTNRSHQVAIHYDLDTNLPPIL
HHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHEEECCCCCCCEEEEEEECCCCCCCCE
VEASQIRQVVLNLLTNAIEAIGERSGSVTLRTGVASLSAADLRRLRLMPTIPPGDYVTLT
ECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEE
VSDTGIGMDEATLRRIFDPFFSTKPKGHGLGLAAVQGIVRRHNGAIRVESTPGLGSTFTV
EECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEE
YLPAAHQATPVVTTNATMPIVLRGTALIVDDDPAIRATLNRILERAGMVTTEAANGQAAL
EEECCCCCCCEEEECCCCEEEEECEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCHHHH
SMLTESALSIDIALVDLAMPGMNGLELLAAIRRRMPQLPVLLMSGNAGEVTKDNLPLDHY
HHHHHHHHHHHHEEEEHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHH
TDFLPKPYRSRDLLEKMSTLLQRVAALRIHGS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AAVSDPPSPSAKTYLRDHSIQLLRDLIWISLIAALAYTIFSPIDPSLMPQRMVVVVPLI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LGLLGAWWLIQRQYLRLASILVISILWLVLAFSAFISGGLQAPAFAGIPLVVIMAGILLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
WCGALTIALLSIGTGALFVRFADLLPPPPVFHSPLVWFITYTLYLLLATRMISQIVTHFY
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSMQETDKELSERKAVEQQLRLSEEKFARLFDSAPFPMLIVRLDDNLILNANAACREFFE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCEEECCCHHHHHHHH
LSSDQIIKQHINRLDWSQLPSRWQAIADTLRQEGTVSEVEFSFCRRDGSTCYTQLTAEIV
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
ELQEGLCAVVAFQDVTPLRRANERLIELASQQEQLATLAREALASTDLNTLFAVAAEQMV
HHHCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QALPISGVEFIDVDIDGNITIRNTWGEVPAQPVPERFFQGLTVDHPGWSNLPAPLAERAA
HHCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHH
DVAQHGAVMLIGGHQRLFGALLVYTSTALDAEAIFFLRSVANVLAVALERFHAEQERRQI
HHHHCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESQMLQTQKLESLGLLAGGIAHDFNNLLTGIMGHTSLALIDLPPNHELQPHLAAIDQAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHH
RAAELCHQLLVYAGRGQRSLEVVDLSNLVREMGNILRLPTNRSHQVAIHYDLDTNLPPIL
HHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHEEECCCCCCCEEEEEEECCCCCCCCE
VEASQIRQVVLNLLTNAIEAIGERSGSVTLRTGVASLSAADLRRLRLMPTIPPGDYVTLT
ECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEE
VSDTGIGMDEATLRRIFDPFFSTKPKGHGLGLAAVQGIVRRHNGAIRVESTPGLGSTFTV
EECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEE
YLPAAHQATPVVTTNATMPIVLRGTALIVDDDPAIRATLNRILERAGMVTTEAANGQAAL
EEECCCCCCCEEEECCCCEEEEECEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCHHHH
SMLTESALSIDIALVDLAMPGMNGLELLAAIRRRMPQLPVLLMSGNAGEVTKDNLPLDHY
HHHHHHHHHHHHEEEEHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHH
TDFLPKPYRSRDLLEKMSTLLQRVAALRIHGS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA