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The map label for this gene is moeZ [H]

Identifier: 222526984

GI number: 222526984

Start: 4682306

End: 4683460

Strand: Direct

Name: moeZ [H]

Synonym: Chy400_3762

Alternate gene names: 222526984

Gene position: 4682306-4683460 (Clockwise)

Preceding gene: 222526983

Following gene: 222526985

Centisome position: 88.87

GC content: 58.7

Gene sequence:

>1155_bases
ATGAGTGAGGTGACCCTCTCGAATGAAGAGATCGCCCGCTATTCGCGTCATCTGATTATGCCCGAAGTGGGGATGGCCGG
TCAGCGCCGGCTCAAACAGGGCAGTGTGTTGCTGATCGGTACCGGTGGTCTGGGATCGCCGCTGGCCCTCTATCTGGCCG
CAGCCGGGGTCGGGCATATCGGCCTGGTTGATTTTGATGTGGTGGATGCGTCCAATCTCCAGCGTCAGATTGTTCACGGT
ACGAGCACCGTCGGTGTGGCGAAGACCGAGTCGGCGAAGCGGCGGTTGCAAGATCTCAATCCGTATATTGAGATCACAAC
CTACGAAACGCAGATCACCTCGCAGAACGCTCTCGATCTGATGCGGCCATACGATGTGATTGTGGATGGCACCGACAACT
TCCCGACCCGCTACCTCACCAACGACGCCTGTGTGTTGCTGGGCAAGCCCAACGTCTACGGCAGCATCTTCCGTTTTGAA
GGTCAGGCTACGGTCTTCTCGGCCCGTGATGGCGGGCCGTGCTACCGCTGTCTCTACCCCGAACCACCACCGCCAGGGCT
GGTACCGAGCTGCGCGGAGGGTGGCGTGCTGGGCGTGCTCCCTGGGGTGATCGGTACCATTCAAGCCACAGAAGTGATAA
AATTGCTTACCGGGATCGGCGAACCACTGATTGGGCGCCTCCTGCTCTACGATGCGCTGAGCATGCGCTTCCGCGAGCTG
AAGCTCCGCCGCAATCCGTCGTGCCCGGTCTGTGGTGATCATCCGACGATCACCGAACTGATCGATTATGAACAATTTTG
TGGCATTGCACCAGAGGAGCCGACATTGTCGAACCAATTTGAGATCACGCCGCGCGAACTCGCGGAATGGCTGGAACGGC
CTGACCGTCCCTTCCTGCTCGATGTGCGCAATCCCTACGAAGTGGCGATTGCCTCTATCCCCGGCACCGACAAGCTGATC
CCGCTCGATCAGTTGCCAGAACGAATCAACGAACTCGATTCGGCACGCGAGATGGTGGTCTACTGCCGGAGCGGTGTGCG
CAGCGGGCGGGCCGTAGAACTGCTGAAAACAGCCGGTTTTCGCAAAGTGAAAAATCTGGTCGGCGGTATTTTACGTTGGG
CCGACGACGTAGATCCGTCGCTACCGAAGTATTGA

Upstream 100 bases:

>100_bases
TTGGCGATGAGGATATTCGCTATCTCGATGGCGAGGCGACACCCCTGCGCGATGGCGATACGGTGAGCATTATTCCGGCA
ATCGCCGGAGGAGGACAGCC

Downstream 100 bases:

>100_bases
CATGCTGAAGCAAAGCATCGTCACCCGCTGGCATCGATTGCGATGAACCGGCGTTGGCGGTGCTTTGTGTAGTATCAGGA
GGACGTGATGATTGGTATTA

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSEVTLSNEEIARYSRHLIMPEVGMAGQRRLKQGSVLLIGTGGLGSPLALYLAAAGVGHIGLVDFDVVDASNLQRQIVHG
TSTVGVAKTESAKRRLQDLNPYIEITTYETQITSQNALDLMRPYDVIVDGTDNFPTRYLTNDACVLLGKPNVYGSIFRFE
GQATVFSARDGGPCYRCLYPEPPPPGLVPSCAEGGVLGVLPGVIGTIQATEVIKLLTGIGEPLIGRLLLYDALSMRFREL
KLRRNPSCPVCGDHPTITELIDYEQFCGIAPEEPTLSNQFEITPRELAEWLERPDRPFLLDVRNPYEVAIASIPGTDKLI
PLDQLPERINELDSAREMVVYCRSGVRSGRAVELLKTAGFRKVKNLVGGILRWADDVDPSLPKY

Sequences:

>Translated_384_residues
MSEVTLSNEEIARYSRHLIMPEVGMAGQRRLKQGSVLLIGTGGLGSPLALYLAAAGVGHIGLVDFDVVDASNLQRQIVHG
TSTVGVAKTESAKRRLQDLNPYIEITTYETQITSQNALDLMRPYDVIVDGTDNFPTRYLTNDACVLLGKPNVYGSIFRFE
GQATVFSARDGGPCYRCLYPEPPPPGLVPSCAEGGVLGVLPGVIGTIQATEVIKLLTGIGEPLIGRLLLYDALSMRFREL
KLRRNPSCPVCGDHPTITELIDYEQFCGIAPEEPTLSNQFEITPRELAEWLERPDRPFLLDVRNPYEVAIASIPGTDKLI
PLDQLPERINELDSAREMVVYCRSGVRSGRAVELLKTAGFRKVKNLVGGILRWADDVDPSLPKY
>Mature_383_residues
SEVTLSNEEIARYSRHLIMPEVGMAGQRRLKQGSVLLIGTGGLGSPLALYLAAAGVGHIGLVDFDVVDASNLQRQIVHGT
STVGVAKTESAKRRLQDLNPYIEITTYETQITSQNALDLMRPYDVIVDGTDNFPTRYLTNDACVLLGKPNVYGSIFRFEG
QATVFSARDGGPCYRCLYPEPPPPGLVPSCAEGGVLGVLPGVIGTIQATEVIKLLTGIGEPLIGRLLLYDALSMRFRELK
LRRNPSCPVCGDHPTITELIDYEQFCGIAPEEPTLSNQFEITPRELAEWLERPDRPFLLDVRNPYEVAIASIPGTDKLIP
LDQLPERINELDSAREMVVYCRSGVRSGRAVELLKTAGFRKVKNLVGGILRWADDVDPSLPKY

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=412, Percent_Identity=44.4174757281553, Blast_Score=299, Evalue=4e-81,
Organism=Homo sapiens, GI4885649, Length=150, Percent_Identity=30, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1787048, Length=247, Percent_Identity=45.3441295546559, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87082356, Length=247, Percent_Identity=42.914979757085, Blast_Score=181, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17540406, Length=393, Percent_Identity=38.1679389312977, Blast_Score=278, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI193203301, Length=165, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71984476, Length=174, Percent_Identity=30.4597701149425, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=406, Percent_Identity=40.1477832512315, Blast_Score=270, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6325438, Length=123, Percent_Identity=32.520325203252, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24582879, Length=396, Percent_Identity=43.1818181818182, Blast_Score=321, Evalue=7e-88,
Organism=Drosophila melanogaster, GI24660640, Length=151, Percent_Identity=28.476821192053, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42152; Mature: 42021

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVTLSNEEIARYSRHLIMPEVGMAGQRRLKQGSVLLIGTGGLGSPLALYLAAAGVGHI
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCE
GLVDFDVVDASNLQRQIVHGTSTVGVAKTESAKRRLQDLNPYIEITTYETQITSQNALDL
EEEEEEECCHHHHHHHHHCCCCCCCEECCHHHHHHHHHCCCEEEEEEEEEEECCCHHHHH
MRPYDVIVDGTDNFPTRYLTNDACVLLGKPNVYGSIFRFEGQATVFSARDGGPCYRCLYP
CCCCEEEEECCCCCCCEEECCCCEEEEECCCCCEEEEEECCCEEEEECCCCCCEEEEECC
EPPPPGLVPSCAEGGVLGVLPGVIGTIQATEVIKLLTGIGEPLIGRLLLYDALSMRFREL
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KLRRNPSCPVCGDHPTITELIDYEQFCGIAPEEPTLSNQFEITPRELAEWLERPDRPFLL
HHHCCCCCCCCCCCCCHHHHHCHHHHCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCEEE
DVRNPYEVAIASIPGTDKLIPLDQLPERINELDSAREMVVYCRSGVRSGRAVELLKTAGF
ECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCH
RKVKNLVGGILRWADDVDPSLPKY
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SEVTLSNEEIARYSRHLIMPEVGMAGQRRLKQGSVLLIGTGGLGSPLALYLAAAGVGHI
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCE
GLVDFDVVDASNLQRQIVHGTSTVGVAKTESAKRRLQDLNPYIEITTYETQITSQNALDL
EEEEEEECCHHHHHHHHHCCCCCCCEECCHHHHHHHHHCCCEEEEEEEEEEECCCHHHHH
MRPYDVIVDGTDNFPTRYLTNDACVLLGKPNVYGSIFRFEGQATVFSARDGGPCYRCLYP
CCCCEEEEECCCCCCCEEECCCCEEEEECCCCCEEEEEECCCEEEEECCCCCCEEEEECC
EPPPPGLVPSCAEGGVLGVLPGVIGTIQATEVIKLLTGIGEPLIGRLLLYDALSMRFREL
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KLRRNPSCPVCGDHPTITELIDYEQFCGIAPEEPTLSNQFEITPRELAEWLERPDRPFLL
HHHCCCCCCCCCCCCCHHHHHCHHHHCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCEEE
DVRNPYEVAIASIPGTDKLIPLDQLPERINELDSAREMVVYCRSGVRSGRAVELLKTAGF
ECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCH
RKVKNLVGGILRWADDVDPSLPKY
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]