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The map label for this gene is aglR [H]

Identifier: 222526934

GI number: 222526934

Start: 4632438

End: 4633457

Strand: Direct

Name: aglR [H]

Synonym: Chy400_3712

Alternate gene names: 222526934

Gene position: 4632438-4633457 (Clockwise)

Preceding gene: 222526931

Following gene: 222526935

Centisome position: 87.92

GC content: 64.12

Gene sequence:

>1020_bases
GTGGCTACGATCAAAGATGTTGCGCGCCGGGCACAGGTATCAACCGCAACCGTCTCCTATGTCCTCAACGGGACCGGTGT
GATCAGTGAACCAACCCGGGCGCGCGTCTTGGCTGCGGTCGCCGAGCTGGGGTATCAGCCCAACCACAGCGCGCGTGCCC
TGCGCACCCGCTCGCACACCATCGGCATTGTCGCTCCCGGCATTGCCGGTCGTCTGGCCGACCCGGCGACCGCCGAACTC
CTGGCCGGTTTGAGCGAGGCAGCTACCACCGCCGGTTATTGCCTGTTGATCGCATCCCCCACTCCTGCCGAATCCGAAGA
CGAACTGGCGTTGCGGCTGGCCCGTAGTGGTCGGGTTGATGGTCTGGTCATCTTCGATCTCCGTCGCAACGACGAGCGAC
CGGCGCGTCTGGCGGCTGCCGGCGTTCCCACCATTGCCATCGGCGCGCCGACCCCCGGTCTTTCCTGCCCGGTTGCCGGT
TTTGATCTCCGTGCCGGCGCTGAACAGGCCGTCAATCACCTGGCGCGGCTCGGTCATCGTCGCATTGCCCTCATCACTGC
CGCCTCTGATCTCAGTGTGAGCGAACATTTCTACACTGGCTATCGGGCAGCACTCCATGCCCATGGCCTCCGCCGTGAAG
CGGCGCTGGTGATCGAAGCCGGAAGCAGTGAAGACGATGGCGTCAATGCGATGCAGGAGCTGCTGGCAATGCGGACACCA
CCGACAGCAGTGCTGGCGGCGTCTGATACGCTCGCCTTTGGAGCCATGCACGCCATCCGCGATGCCGGTTTGACGGTGGG
GAAGGATGTTTCGGTTGTTGGTTGTGATGATTTACCCCTGGCCGCCCACACCTATCCGCCGCTTACCACGCTCCACGCTC
CACATCGCGAGCTTGGTACGGTGCTTGCCCGGCATCTGATCGGGCTGGTTGAACGGCGCAACGTGCCGGATGTAACCCTC
CTGCCGTTACGCCTGATCGTTCGTCACTCCACCGCTGCGCCGGTGCGTGCAGCCGGTTGA

Upstream 100 bases:

>100_bases
TCTCTGTGGTGAACTCATCCCTTGACATCAACACATCCGCGTGCTATACTCCACTTAATCGATTAACCGCTTAATCGTTT
AACTAACGAGCGAGAAGACC

Downstream 100 bases:

>100_bases
GGAATATATCGGTTCTTGTGGCGAGGCGTCTCGCCTCACAAAAGGAGTCAGGAAATGGCCTCGATTAAGTATGACCACGT
CTGGAAGCGCTTCGGCGAAG

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MATIKDVARRAQVSTATVSYVLNGTGVISEPTRARVLAAVAELGYQPNHSARALRTRSHTIGIVAPGIAGRLADPATAEL
LAGLSEAATTAGYCLLIASPTPAESEDELALRLARSGRVDGLVIFDLRRNDERPARLAAAGVPTIAIGAPTPGLSCPVAG
FDLRAGAEQAVNHLARLGHRRIALITAASDLSVSEHFYTGYRAALHAHGLRREAALVIEAGSSEDDGVNAMQELLAMRTP
PTAVLAASDTLAFGAMHAIRDAGLTVGKDVSVVGCDDLPLAAHTYPPLTTLHAPHRELGTVLARHLIGLVERRNVPDVTL
LPLRLIVRHSTAAPVRAAG

Sequences:

>Translated_339_residues
MATIKDVARRAQVSTATVSYVLNGTGVISEPTRARVLAAVAELGYQPNHSARALRTRSHTIGIVAPGIAGRLADPATAEL
LAGLSEAATTAGYCLLIASPTPAESEDELALRLARSGRVDGLVIFDLRRNDERPARLAAAGVPTIAIGAPTPGLSCPVAG
FDLRAGAEQAVNHLARLGHRRIALITAASDLSVSEHFYTGYRAALHAHGLRREAALVIEAGSSEDDGVNAMQELLAMRTP
PTAVLAASDTLAFGAMHAIRDAGLTVGKDVSVVGCDDLPLAAHTYPPLTTLHAPHRELGTVLARHLIGLVERRNVPDVTL
LPLRLIVRHSTAAPVRAAG
>Mature_338_residues
ATIKDVARRAQVSTATVSYVLNGTGVISEPTRARVLAAVAELGYQPNHSARALRTRSHTIGIVAPGIAGRLADPATAELL
AGLSEAATTAGYCLLIASPTPAESEDELALRLARSGRVDGLVIFDLRRNDERPARLAAAGVPTIAIGAPTPGLSCPVAGF
DLRAGAEQAVNHLARLGHRRIALITAASDLSVSEHFYTGYRAALHAHGLRREAALVIEAGSSEDDGVNAMQELLAMRTPP
TAVLAASDTLAFGAMHAIRDAGLTVGKDVSVVGCDDLPLAAHTYPPLTTLHAPHRELGTVLARHLIGLVERRNVPDVTLL
PLRLIVRHSTAAPVRAAG

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=334, Percent_Identity=31.7365269461078, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1790194, Length=306, Percent_Identity=35.2941176470588, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789202, Length=336, Percent_Identity=33.0357142857143, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787948, Length=345, Percent_Identity=31.304347826087, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1789068, Length=338, Percent_Identity=30.7692307692308, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788474, Length=295, Percent_Identity=30.8474576271186, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786540, Length=339, Percent_Identity=33.0383480825959, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1787906, Length=344, Percent_Identity=32.8488372093023, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787580, Length=320, Percent_Identity=27.1875, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789456, Length=358, Percent_Identity=25.6983240223464, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI48994940, Length=316, Percent_Identity=27.2151898734177, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790715, Length=315, Percent_Identity=25.0793650793651, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790689, Length=324, Percent_Identity=27.1604938271605, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35375; Mature: 35244

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2 ; PS00732 RIBOSOMAL_S16

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIKDVARRAQVSTATVSYVLNGTGVISEPTRARVLAAVAELGYQPNHSARALRTRSHT
CCCHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCE
IGIVAPGIAGRLADPATAELLAGLSEAATTAGYCLLIASPTPAESEDELALRLARSGRVD
EEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCCC
GLVIFDLRRNDERPARLAAAGVPTIAIGAPTPGLSCPVAGFDLRAGAEQAVNHLARLGHR
EEEEEEECCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
RIALITAASDLSVSEHFYTGYRAALHAHGLRREAALVIEAGSSEDDGVNAMQELLAMRTP
EEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
PTAVLAASDTLAFGAMHAIRDAGLTVGKDVSVVGCDDLPLAAHTYPPLTTLHAPHRELGT
CCEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
VLARHLIGLVERRNVPDVTLLPLRLIVRHSTAAPVRAAG
HHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ATIKDVARRAQVSTATVSYVLNGTGVISEPTRARVLAAVAELGYQPNHSARALRTRSHT
CCHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCE
IGIVAPGIAGRLADPATAELLAGLSEAATTAGYCLLIASPTPAESEDELALRLARSGRVD
EEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCCC
GLVIFDLRRNDERPARLAAAGVPTIAIGAPTPGLSCPVAGFDLRAGAEQAVNHLARLGHR
EEEEEEECCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
RIALITAASDLSVSEHFYTGYRAALHAHGLRREAALVIEAGSSEDDGVNAMQELLAMRTP
EEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
PTAVLAASDTLAFGAMHAIRDAGLTVGKDVSVVGCDDLPLAAHTYPPLTTLHAPHRELGT
CCEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
VLARHLIGLVERRNVPDVTLLPLRLIVRHSTAAPVRAAG
HHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]