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The map label for this gene is ybaL [H]

Identifier: 222526930

GI number: 222526930

Start: 4624176

End: 4626212

Strand: Direct

Name: ybaL [H]

Synonym: Chy400_3708

Alternate gene names: 222526930

Gene position: 4624176-4626212 (Clockwise)

Preceding gene: 222526928

Following gene: 222526931

Centisome position: 87.76

GC content: 59.35

Gene sequence:

>2037_bases
ATGCATCAAGATATTTCATTGTTGGCAAATCTGGCTATTGCATTGATGGTGGCCTTCGCCGGTGGCTTGCTGGCCCGCAG
AATTGGCCTGCCGACTATCGTCGGCTACCTGCTGGCCGGGATGGCGATTGGCCCGTTTACCCCTGGCTTTGTCGGTGATG
TTGAAGACATCAGCCAGCTTGCCGAAATTGGCGTGATCTTTCTGATGTTTGGGGTTGGTCTCCATTTTTCTCTGAAAGAT
TTGTGGGCTGTGCGCCAGGTGGCATTGCCGGGCGCAATCTTGCAGATGACGATTGCCACTGCGCTGGGGTTTGCGCTCAG
CCAGGTGTGGGGATGGAACCCGTTGTCGGGTCTGATCCTTGGTCTCTCCATCTCGATTGCCAGTACGGTGGTGCTATTGC
GGGGATTGATGGATAACGGCTTGTTGAGCACCAGTGCCGGACGGATCGCCGTCGGCTGGCTGGTGTTGGAAGACCTGGCA
ACGGTGTTGATCCTGGTGTTGTTGCCGATTATCTTTGGTGGTCAGGGAGAGCAATCATTCCTATCCGGCACCTTCTCGCT
GCTAAAGGCCGCCCTGTTTGTGGTCGTGATGCTCTTCATCGGCAGACGACTCTTGCCGAAGCTACTTGACATAATTGCGA
GCACCCGATCCCGCGAGTTGTTCATTCTCGCCGCGGTTGCCATTGCTCTGGGGACAGCGTTTGGTGCCGCTGCGTTCTTC
GATGTCTCGCTGGCCCTGGGGGCGTTTCTGGCCGGTGTAGTGCTGAGCGAGTCACAGTTTAGCCATCAAATTGGCGACGA
TGTGCTTCCCTTCCGCGAGACATTTGCTGTGATCTTCTTCGTCTCGGTAGGAATGATCGTGAACCCGCTGTACCTGTGGG
CAAACGCTGCACAGGTGCTGACCCTAACCGCCCTGATTGTGTTGGGCAAGGCATTTTTCACTCAGTTGCTCGGTTTTATG
CTGCCGGCCAGTGGCCGCACGATGCTGATCGTCGCTGCCGGTCTCAGTCAGATCGGCGAGTTTTCCTTCATTCTGGGAAA
GGCCGGGATGCGGCTTGGTTTGCTCTCGCAAGACCAGTACTCGCTGATACTCGCGGGCTCGCTGCTGTCGATAATGGTGA
ATCCGCTGATGTTTCGTTCTATCAAACCCATCGAACGACTCATGCAGCGACTGTCGCCGCGCCTCTGGGAGCGCTTCGAT
AGCCATCCCCTCCAGCCCGCCGATCTGGCCCTCCCCAAAGAGGGGCACGTGGTAGTGGTTGGCTATGGGCGGGTTGGTCA
ACACATCGTTACCGTCCTTGAACGGCTGGGGATTCCGCGCCTGGTGGTTGAGATCGATTCGGGGCGGGCTGCCGAATTTA
ATGCCCGTGGTGTTCCCACGCTCTTCGGCGATGCTGCCAATTCCGACGTGCTAATCCATGCGGGTCTGGAACGAGCGCGG
GCGCTGGTGGTGACCCTGCCCGACGAGACGGCAACCGAGATGGTGGTGGCAGCGGCGCGCAAGATCGCGCCGAATCTCCC
GATCATTGCCCGTGCGGCGACAACGAAGGGGGTAGGCCGGCTGCTCAATCTCGGTGCGCACGATGTCATTCACCCCGAAC
TGGAAGGCGGTCTGGAAGTTATGCGCCATACGCTGCTCTGTCTGGGGTACCCGGCCACTCAGGTGCAGGGCTATACCGAT
GCCGTGCGGCGTGACGAGTATGATACCTCGGTCTCCAGCCCTGCCGAGCACCAGGCGCTCGATCAAATGGTACGCGCTGC
ACGCGGGATCGAGATTGCCTGGCGGCTGGTTGGCGAACGCAGTCCAATCGTCGGCCAATCGCTGGCCGAAGCGAATATTC
GTGCCCGCACCGGCGCCTCGGTGATCGCGCTGATCCGCGATCAACAGCTCATTGCCAACCCCAAGTCGAGTACCATCTTC
CGCCCCGGTGATCTGCTCGGTCTGATCGGTGAGAGCGATCAGATCGCGGCTGCCGAGCAGTTACTGGCCGACACCCCGGC
ACCAGCACTGGCGCTGGCCGAGGAGCGTACCGTGTGA

Upstream 100 bases:

>100_bases
TCATAACAACACTCTCCTGAATCTACGCCATGCTGCGTACATGTTTCCCGTTCCCCGTTGATCTGAAAAAGATGTTGCTT
TTCGCAATTGGAGTAGAGCA

Downstream 100 bases:

>100_bases
GGGGGGCATATCCTGCGGGGGGAGTGGGGAATGGGGAGTAGGGAGAGGAGATGGGCATGCTCCGTATGGCTTCCGGTCAC
CGCGATCCTGGCCCCCCTCC

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MHQDISLLANLAIALMVAFAGGLLARRIGLPTIVGYLLAGMAIGPFTPGFVGDVEDISQLAEIGVIFLMFGVGLHFSLKD
LWAVRQVALPGAILQMTIATALGFALSQVWGWNPLSGLILGLSISIASTVVLLRGLMDNGLLSTSAGRIAVGWLVLEDLA
TVLILVLLPIIFGGQGEQSFLSGTFSLLKAALFVVVMLFIGRRLLPKLLDIIASTRSRELFILAAVAIALGTAFGAAAFF
DVSLALGAFLAGVVLSESQFSHQIGDDVLPFRETFAVIFFVSVGMIVNPLYLWANAAQVLTLTALIVLGKAFFTQLLGFM
LPASGRTMLIVAAGLSQIGEFSFILGKAGMRLGLLSQDQYSLILAGSLLSIMVNPLMFRSIKPIERLMQRLSPRLWERFD
SHPLQPADLALPKEGHVVVVGYGRVGQHIVTVLERLGIPRLVVEIDSGRAAEFNARGVPTLFGDAANSDVLIHAGLERAR
ALVVTLPDETATEMVVAAARKIAPNLPIIARAATTKGVGRLLNLGAHDVIHPELEGGLEVMRHTLLCLGYPATQVQGYTD
AVRRDEYDTSVSSPAEHQALDQMVRAARGIEIAWRLVGERSPIVGQSLAEANIRARTGASVIALIRDQQLIANPKSSTIF
RPGDLLGLIGESDQIAAAEQLLADTPAPALALAEERTV

Sequences:

>Translated_678_residues
MHQDISLLANLAIALMVAFAGGLLARRIGLPTIVGYLLAGMAIGPFTPGFVGDVEDISQLAEIGVIFLMFGVGLHFSLKD
LWAVRQVALPGAILQMTIATALGFALSQVWGWNPLSGLILGLSISIASTVVLLRGLMDNGLLSTSAGRIAVGWLVLEDLA
TVLILVLLPIIFGGQGEQSFLSGTFSLLKAALFVVVMLFIGRRLLPKLLDIIASTRSRELFILAAVAIALGTAFGAAAFF
DVSLALGAFLAGVVLSESQFSHQIGDDVLPFRETFAVIFFVSVGMIVNPLYLWANAAQVLTLTALIVLGKAFFTQLLGFM
LPASGRTMLIVAAGLSQIGEFSFILGKAGMRLGLLSQDQYSLILAGSLLSIMVNPLMFRSIKPIERLMQRLSPRLWERFD
SHPLQPADLALPKEGHVVVVGYGRVGQHIVTVLERLGIPRLVVEIDSGRAAEFNARGVPTLFGDAANSDVLIHAGLERAR
ALVVTLPDETATEMVVAAARKIAPNLPIIARAATTKGVGRLLNLGAHDVIHPELEGGLEVMRHTLLCLGYPATQVQGYTD
AVRRDEYDTSVSSPAEHQALDQMVRAARGIEIAWRLVGERSPIVGQSLAEANIRARTGASVIALIRDQQLIANPKSSTIF
RPGDLLGLIGESDQIAAAEQLLADTPAPALALAEERTV
>Mature_678_residues
MHQDISLLANLAIALMVAFAGGLLARRIGLPTIVGYLLAGMAIGPFTPGFVGDVEDISQLAEIGVIFLMFGVGLHFSLKD
LWAVRQVALPGAILQMTIATALGFALSQVWGWNPLSGLILGLSISIASTVVLLRGLMDNGLLSTSAGRIAVGWLVLEDLA
TVLILVLLPIIFGGQGEQSFLSGTFSLLKAALFVVVMLFIGRRLLPKLLDIIASTRSRELFILAAVAIALGTAFGAAAFF
DVSLALGAFLAGVVLSESQFSHQIGDDVLPFRETFAVIFFVSVGMIVNPLYLWANAAQVLTLTALIVLGKAFFTQLLGFM
LPASGRTMLIVAAGLSQIGEFSFILGKAGMRLGLLSQDQYSLILAGSLLSIMVNPLMFRSIKPIERLMQRLSPRLWERFD
SHPLQPADLALPKEGHVVVVGYGRVGQHIVTVLERLGIPRLVVEIDSGRAAEFNARGVPTLFGDAANSDVLIHAGLERAR
ALVVTLPDETATEMVVAAARKIAPNLPIIARAATTKGVGRLLNLGAHDVIHPELEGGLEVMRHTLLCLGYPATQVQGYTD
AVRRDEYDTSVSSPAEHQALDQMVRAARGIEIAWRLVGERSPIVGQSLAEANIRARTGASVIALIRDQQLIANPKSSTIF
RPGDLLGLIGESDQIAAAEQLLADTPAPALALAEERTV

Specific function: Unknown

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=399, Percent_Identity=26.8170426065163, Blast_Score=129, Evalue=7e-30,
Organism=Escherichia coli, GI1786685, Length=542, Percent_Identity=45.0184501845018, Blast_Score=400, Evalue=1e-112,
Organism=Escherichia coli, GI1789749, Length=555, Percent_Identity=31.1711711711712, Blast_Score=209, Evalue=7e-55,
Organism=Escherichia coli, GI1786232, Length=545, Percent_Identity=27.7064220183486, Blast_Score=185, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 72228; Mature: 72228

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQDISLLANLAIALMVAFAGGLLARRIGLPTIVGYLLAGMAIGPFTPGFVGDVEDISQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
AEIGVIFLMFGVGLHFSLKDLWAVRQVALPGAILQMTIATALGFALSQVWGWNPLSGLIL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GLSISIASTVVLLRGLMDNGLLSTSAGRIAVGWLVLEDLATVLILVLLPIIFGGQGEQSF
HHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LSGTFSLLKAALFVVVMLFIGRRLLPKLLDIIASTRSRELFILAAVAIALGTAFGAAAFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
DVSLALGAFLAGVVLSESQFSHQIGDDVLPFRETFAVIFFVSVGMIVNPLYLWANAAQVL
HHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLTALIVLGKAFFTQLLGFMLPASGRTMLIVAAGLSQIGEFSFILGKAGMRLGLLSQDQY
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCCCC
SLILAGSLLSIMVNPLMFRSIKPIERLMQRLSPRLWERFDSHPLQPADLALPKEGHVVVV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCEEEE
GYGRVGQHIVTVLERLGIPRLVVEIDSGRAAEFNARGVPTLFGDAANSDVLIHAGLERAR
ECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCEEEECCHHCCC
ALVVTLPDETATEMVVAAARKIAPNLPIIARAATTKGVGRLLNLGAHDVIHPELEGGLEV
EEEEECCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MRHTLLCLGYPATQVQGYTDAVRRDEYDTSVSSPAEHQALDQMVRAARGIEIAWRLVGER
HHHHHHHHCCCHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCC
SPIVGQSLAEANIRARTGASVIALIRDQQLIANPKSSTIFRPGDLLGLIGESDQIAAAEQ
CCCCCHHHHHCCCHHCCCCCEEEHHHCCHHHCCCCCCCEECCCCCEEECCCCCHHHHHHH
LLADTPAPALALAEERTV
HHHCCCCCHHHCCCCCCC
>Mature Secondary Structure
MHQDISLLANLAIALMVAFAGGLLARRIGLPTIVGYLLAGMAIGPFTPGFVGDVEDISQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
AEIGVIFLMFGVGLHFSLKDLWAVRQVALPGAILQMTIATALGFALSQVWGWNPLSGLIL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GLSISIASTVVLLRGLMDNGLLSTSAGRIAVGWLVLEDLATVLILVLLPIIFGGQGEQSF
HHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LSGTFSLLKAALFVVVMLFIGRRLLPKLLDIIASTRSRELFILAAVAIALGTAFGAAAFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
DVSLALGAFLAGVVLSESQFSHQIGDDVLPFRETFAVIFFVSVGMIVNPLYLWANAAQVL
HHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLTALIVLGKAFFTQLLGFMLPASGRTMLIVAAGLSQIGEFSFILGKAGMRLGLLSQDQY
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCCCC
SLILAGSLLSIMVNPLMFRSIKPIERLMQRLSPRLWERFDSHPLQPADLALPKEGHVVVV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCEEEE
GYGRVGQHIVTVLERLGIPRLVVEIDSGRAAEFNARGVPTLFGDAANSDVLIHAGLERAR
ECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCEEEECCHHCCC
ALVVTLPDETATEMVVAAARKIAPNLPIIARAATTKGVGRLLNLGAHDVIHPELEGGLEV
EEEEECCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MRHTLLCLGYPATQVQGYTDAVRRDEYDTSVSSPAEHQALDQMVRAARGIEIAWRLVGER
HHHHHHHHCCCHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCC
SPIVGQSLAEANIRARTGASVIALIRDQQLIANPKSSTIFRPGDLLGLIGESDQIAAAEQ
CCCCCHHHHHCCCHHCCCCCEEEHHHCCHHHCCCCCCCEECCCCCEEECCCCCHHHHHHH
LLADTPAPALALAEERTV
HHHCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]