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The map label for this gene is 222526817

Identifier: 222526817

GI number: 222526817

Start: 4466148

End: 4467041

Strand: Reverse

Name: 222526817

Synonym: Chy400_3592

Alternate gene names: NA

Gene position: 4467041-4466148 (Counterclockwise)

Preceding gene: 222526818

Following gene: 222526816

Centisome position: 84.78

GC content: 55.59

Gene sequence:

>894_bases
ATGTCCCACACCGATTTTGTTACCACCAGCCGTGGCCTGAATCGCAACAGTCCGCCAATGCGACTCTTCGAGAAGGCCAA
GCGGTTTGGCATCTGGAATCCCTCGCTCATCGATCTGAGCCGTGATATTCGTGATTGGGAACAGCTCCGCGACGAGGAAC
GCGATCTGTTGTTGCGCCTCACTGCGCTGTTTCAGGCCGGTGAAGAGGCGGTGACGCTCGATCTGCTTCCGCTGATCCGC
ACGATTGCCAGGGAAGGTCGGTTAGAGGAGGAGCTGTATCTCACCACCTTCCTCTTTGAAGAAGCCAAACATACCGACTT
CTTCGCTCGCTTTATCAGTGAAGTCGCCCGTGTCGATCCCGATCTGAGCCGGTACCACACGGCCAGTTATCGGGCGTTGA
TTTACGAAGCTCTACCGGCTGCCCTGCATCGCCTCGATCACGATCCATCGCCGCTCAATCTCGCCGAAGCATCGCTTACC
TACAATATGATTGTCGAGGGTGTGCTGGCCGAGACCGGCTATCACGCCTATTTCACCATCCTCGATAGCCAGGACATCAT
GCCGGGCACGCGCGAGGGGATTCGCCTGCTCAAACAGGATGAGTCGCGCCATATTGCCTACGGCGTCTACCTGCTCTCGC
GCCTCATTGCCACCGATCCACAGGTCTGGGATCACATTGTCGAGCGGATGAATGAGCTGGTACTGTATGCGATGGGGGTC
ATCGACGAAATCTTTGCCTGCTATGATCCGATGCCGTTTAATTTGCAGATCGAGACGTTCAGTACATTTGCTCTGAACCA
GTTTCAGCGTCGTCTCAACCGGCTCGAATTAGCCAGCCGGCAGAGCATGAACGAGATCGATAACCTGGCAACCGACGATG
AGGAAAGCGTATGA

Upstream 100 bases:

>100_bases
CGCTGTGGGCCGGTACTGCGCTGCTCGATTGTCTGACGTTGCCGATCAGTGTTGATGCGAAGGATAGGTTGCAAGGTTGA
AGGTTTGCAGGAGTTTATGT

Downstream 100 bases:

>100_bases
ATGCCTTTGCCGGTCGGGTCGTGCTGCTCACCGGTGCGGGTGGCGGATTGGGGCGAGAGTTTGCCCGCCAGTTACTGGCC
GCAGGAGCCGACCTTATCCT

Product: ribonucleotide-diphosphate reductase subunit beta

Products: ribonucleoside diphosphate; thioredoxin

Alternate protein names: Ribonucleotide reductase R2 subunit homolog; Ribonucleotide reductase small subunit homolog [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSHTDFVTTSRGLNRNSPPMRLFEKAKRFGIWNPSLIDLSRDIRDWEQLRDEERDLLLRLTALFQAGEEAVTLDLLPLIR
TIAREGRLEEELYLTTFLFEEAKHTDFFARFISEVARVDPDLSRYHTASYRALIYEALPAALHRLDHDPSPLNLAEASLT
YNMIVEGVLAETGYHAYFTILDSQDIMPGTREGIRLLKQDESRHIAYGVYLLSRLIATDPQVWDHIVERMNELVLYAMGV
IDEIFACYDPMPFNLQIETFSTFALNQFQRRLNRLELASRQSMNEIDNLATDDEESV

Sequences:

>Translated_297_residues
MSHTDFVTTSRGLNRNSPPMRLFEKAKRFGIWNPSLIDLSRDIRDWEQLRDEERDLLLRLTALFQAGEEAVTLDLLPLIR
TIAREGRLEEELYLTTFLFEEAKHTDFFARFISEVARVDPDLSRYHTASYRALIYEALPAALHRLDHDPSPLNLAEASLT
YNMIVEGVLAETGYHAYFTILDSQDIMPGTREGIRLLKQDESRHIAYGVYLLSRLIATDPQVWDHIVERMNELVLYAMGV
IDEIFACYDPMPFNLQIETFSTFALNQFQRRLNRLELASRQSMNEIDNLATDDEESV
>Mature_296_residues
SHTDFVTTSRGLNRNSPPMRLFEKAKRFGIWNPSLIDLSRDIRDWEQLRDEERDLLLRLTALFQAGEEAVTLDLLPLIRT
IAREGRLEEELYLTTFLFEEAKHTDFFARFISEVARVDPDLSRYHTASYRALIYEALPAALHRLDHDPSPLNLAEASLTY
NMIVEGVLAETGYHAYFTILDSQDIMPGTREGIRLLKQDESRHIAYGVYLLSRLIATDPQVWDHIVERMNELVLYAMGVI
DEIFACYDPMPFNLQIETFSTFALNQFQRRLNRLELASRQSMNEIDNLATDDEESV

Specific function: Probable oxidase that might be involved in lipid metabolism [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily [H]

Homologues:

Organism=Drosophila melanogaster, GI18079279, Length=240, Percent_Identity=24.5833333333333, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: 1.17.4.1

Molecular weight: Translated: 34437; Mature: 34306

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHTDFVTTSRGLNRNSPPMRLFEKAKRFGIWNPSLIDLSRDIRDWEQLRDEERDLLLRL
CCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TALFQAGEEAVTLDLLPLIRTIAREGRLEEELYLTTFLFEEAKHTDFFARFISEVARVDP
HHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DLSRYHTASYRALIYEALPAALHRLDHDPSPLNLAEASLTYNMIVEGVLAETGYHAYFTI
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEE
LDSQDIMPGTREGIRLLKQDESRHIAYGVYLLSRLIATDPQVWDHIVERMNELVLYAMGV
ECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IDEIFACYDPMPFNLQIETFSTFALNQFQRRLNRLELASRQSMNEIDNLATDDEESV
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SHTDFVTTSRGLNRNSPPMRLFEKAKRFGIWNPSLIDLSRDIRDWEQLRDEERDLLLRL
CCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TALFQAGEEAVTLDLLPLIRTIAREGRLEEELYLTTFLFEEAKHTDFFARFISEVARVDP
HHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DLSRYHTASYRALIYEALPAALHRLDHDPSPLNLAEASLTYNMIVEGVLAETGYHAYFTI
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEE
LDSQDIMPGTREGIRLLKQDESRHIAYGVYLLSRLIATDPQVWDHIVERMNELVLYAMGV
ECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IDEIFACYDPMPFNLQIETFSTFALNQFQRRLNRLELASRQSMNEIDNLATDDEESV
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside diphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA