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The map label for this gene is rnz [H]

Identifier: 222526716

GI number: 222526716

Start: 4346816

End: 4347583

Strand: Direct

Name: rnz [H]

Synonym: Chy400_3487

Alternate gene names: 222526716

Gene position: 4346816-4347583 (Clockwise)

Preceding gene: 222526715

Following gene: 222526720

Centisome position: 82.5

GC content: 60.03

Gene sequence:

>768_bases
ATGACAGCACGGGTTGTATTACTGGGTACCGGAACAGGTTTGCCCGATCCTGATCGAGCGTATACGCATCTGGTCTGGGA
TGGGCCGGGTGGGCCATTCCTGGTTGATGTCGGTGGTGAGAGCTACCGTCGCATGCTGGCGGCCGGTATCGATCCACAGA
GGCTCACCGGCGTTCTCCTGACCCACAGCCACTGTGATCACATTAACGGCTTACCGGCGCTCCTCTTCAGCCTCCGTCTG
GGTGGGCGTACCGAACCGTTACCGATCTACAGCTTACCGGCAACCATCGAACTGACCGCCGCGTTCCTGGCCGCAGCGGG
TCTGGAAGATTGTGCCACACCGGTCATCTGGCAACCAGTTACCCCCGGCGAACCCCTACAGCTTCGTGATGGCCTGGTCA
TCACGACGGCAATAACCGCGCACAGCCGACCCTGTCTTGCTCTGCGCTTTGCAGCTCCGAACGTGCCGGCAGTGTGCTAT
TCCTCTGATACTGAACCGTGTCCGGCAGTCGTCGATCTGGCTACCGGCGCACAGATATTGATCCACGAAGCGACCACTGC
TGAACCATTTGCCGGCCATACCACCCCGCGTCAGGCCGGTGCCGTGGCCGCTGCTGCCGGTGTGCGTCGGCTTATCCTGG
TACATTTCAGTCCACGCTGGACAATGCCGGTTGATCAGGCGTTGGCCGAAATTGCCGTCGGCGGTTTTCATGGTGACGCA
GCAGTAGGGGTTGATCTACAAGAGCTAACCCTGCTTCCAGAGAGGTAG

Upstream 100 bases:

>100_bases
ATATCAGCAATATTCTTTCAAAGCTACACCTGGCCGACCGTACCCAGGTAGCGATCTACGCCCTCCGCAAGCGGCTTGTC
CCAATCGATGAGGAAGAATA

Downstream 100 bases:

>100_bases
ACTGTCGAACTACATCCACATCCCGCGAACGGTTAACTGCGCCTGGTGTCATCCGGCGTACAAACGCCATCAGGTTGGAG
TGTTTGGTAACTCTGCGGCA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTARVVLLGTGTGLPDPDRAYTHLVWDGPGGPFLVDVGGESYRRMLAAGIDPQRLTGVLLTHSHCDHINGLPALLFSLRL
GGRTEPLPIYSLPATIELTAAFLAAAGLEDCATPVIWQPVTPGEPLQLRDGLVITTAITAHSRPCLALRFAAPNVPAVCY
SSDTEPCPAVVDLATGAQILIHEATTAEPFAGHTTPRQAGAVAAAAGVRRLILVHFSPRWTMPVDQALAEIAVGGFHGDA
AVGVDLQELTLLPER

Sequences:

>Translated_255_residues
MTARVVLLGTGTGLPDPDRAYTHLVWDGPGGPFLVDVGGESYRRMLAAGIDPQRLTGVLLTHSHCDHINGLPALLFSLRL
GGRTEPLPIYSLPATIELTAAFLAAAGLEDCATPVIWQPVTPGEPLQLRDGLVITTAITAHSRPCLALRFAAPNVPAVCY
SSDTEPCPAVVDLATGAQILIHEATTAEPFAGHTTPRQAGAVAAAAGVRRLILVHFSPRWTMPVDQALAEIAVGGFHGDA
AVGVDLQELTLLPER
>Mature_254_residues
TARVVLLGTGTGLPDPDRAYTHLVWDGPGGPFLVDVGGESYRRMLAAGIDPQRLTGVLLTHSHCDHINGLPALLFSLRLG
GRTEPLPIYSLPATIELTAAFLAAAGLEDCATPVIWQPVTPGEPLQLRDGLVITTAITAHSRPCLALRFAAPNVPAVCYS
SDTEPCPAVVDLATGAQILIHEATTAEPFAGHTTPRQAGAVAAAAGVRRLILVHFSPRWTMPVDQALAEIAVGGFHGDAA
VGVDLQELTLLPER

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 26761; Mature: 26630

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARVVLLGTGTGLPDPDRAYTHLVWDGPGGPFLVDVGGESYRRMLAAGIDPQRLTGVLL
CCEEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHCCCCHHHHEEEEE
THSHCDHINGLPALLFSLRLGGRTEPLPIYSLPATIELTAAFLAAAGLEDCATPVIWQPV
ECCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCCHHHHCCCEEEECC
TPGEPLQLRDGLVITTAITAHSRPCLALRFAAPNVPAVCYSSDTEPCPAVVDLATGAQIL
CCCCCEEECCCEEEEEEEECCCCCEEEEEEECCCCCEEEECCCCCCCCCEEECCCCCEEE
IHEATTAEPFAGHTTPRQAGAVAAAAGVRRLILVHFSPRWTMPVDQALAEIAVGGFHGDA
EEECCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCE
AVGVDLQELTLLPER
EECCCHHHEEECCCC
>Mature Secondary Structure 
TARVVLLGTGTGLPDPDRAYTHLVWDGPGGPFLVDVGGESYRRMLAAGIDPQRLTGVLL
CEEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHCCCCHHHHEEEEE
THSHCDHINGLPALLFSLRLGGRTEPLPIYSLPATIELTAAFLAAAGLEDCATPVIWQPV
ECCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCCHHHHCCCEEEECC
TPGEPLQLRDGLVITTAITAHSRPCLALRFAAPNVPAVCYSSDTEPCPAVVDLATGAQIL
CCCCCEEECCCEEEEEEEECCCCCEEEEEEECCCCCEEEECCCCCCCCCEEECCCCCEEE
IHEATTAEPFAGHTTPRQAGAVAAAAGVRRLILVHFSPRWTMPVDQALAEIAVGGFHGDA
EEECCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCE
AVGVDLQELTLLPER
EECCCHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]