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The map label for this gene is cymR [H]

Identifier: 222526707

GI number: 222526707

Start: 4338425

End: 4338865

Strand: Direct

Name: cymR [H]

Synonym: Chy400_3478

Alternate gene names: 222526707

Gene position: 4338425-4338865 (Clockwise)

Preceding gene: 222526702

Following gene: 222526712

Centisome position: 82.34

GC content: 58.05

Gene sequence:

>441_bases
ATGCGTATCTCAAGTAAAGGCGATTATGGCCTGCGTGCTCTGTTCGATCTGGCGCAACGGTACGGCGAGGGGCCGATCCA
GAGCGAAGCTATTGCCATCCGCCAGGGCATTCCGGTCAATTATCTCAACCAGTTGCTCATCACCTTGCGACGGGCCGGCT
TAGTCGAGAGTCTCCGGGGGCCGCAGGGTGGTCATCTCCTTGCTCGTTCCCCCGAATCGATTACGCTCCTGGAAGTGCTA
ACCGTCCTCGAAGGTCCTATTTTGCCCGCTGAAGGTGGTCGCGATGATCTTCAGCCTACCGAGCCGTCAGATCGCGCCGT
GATCGATGAAATCTGGAGCGAGTTGCGCACCACCATCGAACGCCGCCTGGCTGCCATCACGCTTGATGATCTCTGCCAGC
GTAAGCGCAGCCAGGATGGCACGGTGATGTATTACATCTGA

Upstream 100 bases:

>100_bases
ATACCACAAGTTGGCGTTTGTTGGGAAGAGGGAATGTTGACGCACGCCGGGCTTATTGCTACAATTGTTAAGTGATCTAC
TTGACTATATGGAGGGGTGC

Downstream 100 bases:

>100_bases
AAAGCGAACGGTCTTCTTTACAGGTCTCGTCTTCACATAATAACCCATGTTGTCACCTATGCTGCGAGCAGGCTACGCGC
AGCTAACTGCCAGGATGAAC

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MRISSKGDYGLRALFDLAQRYGEGPIQSEAIAIRQGIPVNYLNQLLITLRRAGLVESLRGPQGGHLLARSPESITLLEVL
TVLEGPILPAEGGRDDLQPTEPSDRAVIDEIWSELRTTIERRLAAITLDDLCQRKRSQDGTVMYYI

Sequences:

>Translated_146_residues
MRISSKGDYGLRALFDLAQRYGEGPIQSEAIAIRQGIPVNYLNQLLITLRRAGLVESLRGPQGGHLLARSPESITLLEVL
TVLEGPILPAEGGRDDLQPTEPSDRAVIDEIWSELRTTIERRLAAITLDDLCQRKRSQDGTVMYYI
>Mature_146_residues
MRISSKGDYGLRALFDLAQRYGEGPIQSEAIAIRQGIPVNYLNQLLITLRRAGLVESLRGPQGGHLLARSPESITLLEVL
TVLEGPILPAEGGRDDLQPTEPSDRAVIDEIWSELRTTIERRLAAITLDDLCQRKRSQDGTVMYYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=87, Percent_Identity=42.5287356321839, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16243; Mature: 16243

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRISSKGDYGLRALFDLAQRYGEGPIQSEAIAIRQGIPVNYLNQLLITLRRAGLVESLRG
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
PQGGHLLARSPESITLLEVLTVLEGPILPAEGGRDDLQPTEPSDRAVIDEIWSELRTTIE
CCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RRLAAITLDDLCQRKRSQDGTVMYYI
HHHHHHHHHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure
MRISSKGDYGLRALFDLAQRYGEGPIQSEAIAIRQGIPVNYLNQLLITLRRAGLVESLRG
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
PQGGHLLARSPESITLLEVLTVLEGPILPAEGGRDDLQPTEPSDRAVIDEIWSELRTTIE
CCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RRLAAITLDDLCQRKRSQDGTVMYYI
HHHHHHHHHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]