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The map label for this gene is fadN [H]

Identifier: 222526706

GI number: 222526706

Start: 4335771

End: 4338191

Strand: Reverse

Name: fadN [H]

Synonym: Chy400_3477

Alternate gene names: 222526706

Gene position: 4338191-4335771 (Counterclockwise)

Preceding gene: 222526708

Following gene: 222526705

Centisome position: 82.34

GC content: 59.07

Gene sequence:

>2421_bases
ATGACCTATCAGATCAAGCGCGTTGGCGTGATCGGCGCCGGCACAATGGGTGCCGCAATTGCTGCTCTGGTGGCCGGAAC
CGGTATTCCGGTCATCTTGCTCGATGTCCCACCCTCTTCACTTACCGCTGAGGAAGAAGCAAAAGGTCTCACCCTCAACC
ACCCGCAAGTCCGCAACCGGATTGTACAGCAGGGTTTTGAGCGGATGCGCAAGGCCCGGCCATCAAACCTCTACAGTGAG
CGGACTGCCGAACTGATTACGCTGGGCAACACTGAAGACGATTTTCACCGGCTGGCCGAATGCGACTGGATCGTCGAAGC
GATTGTCGAGCAAATTGGCCCCAAGCAGTCCTTGATGGCGCGCCTGGAAGAGGTGCGCAAACCGCACGCAATCGTCACCA
CCAACACGTCAGGTATTCCGATCCGAATCATCGCGGAAGGGCGGAGTGAAGCCTTCCGCCGGCACTTCTTCGGCAGCCAC
TTCTTCAACCCACCACGGTACCTGCGACTGCTCGAAATTATTCCCGGCGACGATGCCGATCCGGCTGTAGTAGCGGCGTT
CCGTCAGTTTGCCGAAGAGCGGCTGGGCAAAGGGGTAGTTATCTGTAAAGATCGCCCCAACTTTATCGGCAACCGAATCT
TTGTGTACGCCGGACAGGTTCTGATCAATTATGCCCTGCAACACGGCTACCGGGTTGAAGAGGTGGATGCCCTCACCGGC
CCGCTGATTGGACGCCCGAATACGGCGAGCTTCCGCCTGCTCGACCAGGTTGGGATCGATGTGATGGCTTACGTCGCCGC
AAATCTGTACGATGCGATTCCCGATGACGAGAGTCGTGATGTCTACCGGCAGAATGACCTGACGCAAAAGCTGGTGGCCG
CCGGCAAGCTGGGGAAGAAGGTCGGCCAGGGCTTTTACAAAGAGGTGCGGCAGAATGGGAAACGTGAATTCTGGGCGCTC
GACTTGCAGACGCTCGAATACGTACCACCCCAGGGAACCGCGGCAGTTGATGAACTGATCGGTGCAGCACGTAAGATCAA
ATCGCTCCCCGAACGCCTGCGCTTCATTCTCGGTCGGGCCGAGGAAGGTGATCGGGGTGCCCAACTGGTCGCCGCTGCCG
TCTACCCCATGATGGCCTACGCTGCCCGCCGCTTACCTGAGATTGCCGACAGTGTTGCCGACGTTGACAACGCCATGCGC
TGGGGTTTTGCCCACGAGCAGGGACCATTCCAGCTCTGGCAGGCGATGGGGATCGCGGAAACGGCGAGTCGGATGCGCGC
TTTTGGTGAGAGTCTCCCGGCATGGGTGGATCAACTAATTGCCACCGATGGTCGTTTTTACGGTGAGATCGACGGCACGC
CAGCGGCCTATAACGTTGCGACAGGCCGACTGGAACCGATTCAGCGTGACCCACGCGCAATCGATCTGGCTGCGCTCAAA
GCGGCTGGACGCGAACTGCATGGGAATGAGAGCGCCAGTGTCATCGATCTTGGTGATGGGGTGTTGTGCTTCGAGCTGCA
CTCGAAAGCGAACACCATTGGCGGACAGGTAATCGAGATGCTGATTAAGGCTCTCGACGAACTGGATCAGGGACCGTGGG
TTGGCATGGTGGTCGGCAATCAGGGGCCACGCTTCTCGGCAGGTCTCGATCTCAACGATGTCGGTGCAGCGGTAATGACC
GGGGCCTGGGACGATATTGACGAGTACGCAGCCCTGGTTCAACAGACGTTCCGGCGCATGCGCGATAGCGCCAAACCTAT
TGTGAGCGCTCCGTTCGGCCAGACATTAGGCGGCGGGGTTGAACTTTCGATGCACAGTGCGGCCTCGGTTGCGGCTGCCG
AAACCTACATGGGCTTTGTCGAATTCGGTGTGGGGGTGATTCCAGCCTGGGGCGGCTGCACCGAGATGAACCGGCGAATT
ATTGCCGCCGCCGTGCGCAACGGCAGTGATCCACTGAAAGCCTTCCAGCAGGTCTTCGAGACGATTGCGCTGGCGAAGGT
CGCCACCAGTGCTCACGAAGCCAAAGAACTTGGCCTGCTACGGCCAACCGACCGGATTGTCTTCAACCCGGACTACCTGA
TCGGTGAAGCGAAACGCGAAGTGTTACGCCTGGTCGCGGAGGGATATACACCGGCAGTCACAGCAAAACCCTGCTATGCG
CTAGGGCGGGATGGTCTGGCAGCGGCACGGATTGCCATCTATCAGATGCGCGAAGGCGGTTTTGCCACGCCATACGATGC
AGTGATTGCCGACAAGCTGGCCTACGTGCTGTGTGGTGGCGAACTGAGCAGCCCGCAGTGGGTTGACGATGTGTATATGC
ACGCGCTCGAACGGGCGATGGTTCTCGAATTGCTTAAAGACCCGCGCACGCAGGCCCGCGCCCGGCATATGCTCGAACAC
GGTAAGCCATTGCGGAATTAA

Upstream 100 bases:

>100_bases
GGTTAGGTCGCGACCAACCATACAACCCGACTTGTGCGTCACGATGTGGAGAGCGCTTTCGCTTGTGGAAAGCGCGGCTG
CAATGGTCAAGGAGGACCCG

Downstream 100 bases:

>100_bases
GCTGGGTGTATCTTGTTGTGGGTGAGAGACGTTGCCGTTGCGATGACTGTTCACAGGCGGCAATTATACCGAGAGACATC
GGGTTACAGATCATCAGCCG

Product: 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 806; Mature: 805

Protein sequence:

>806_residues
MTYQIKRVGVIGAGTMGAAIAALVAGTGIPVILLDVPPSSLTAEEEAKGLTLNHPQVRNRIVQQGFERMRKARPSNLYSE
RTAELITLGNTEDDFHRLAECDWIVEAIVEQIGPKQSLMARLEEVRKPHAIVTTNTSGIPIRIIAEGRSEAFRRHFFGSH
FFNPPRYLRLLEIIPGDDADPAVVAAFRQFAEERLGKGVVICKDRPNFIGNRIFVYAGQVLINYALQHGYRVEEVDALTG
PLIGRPNTASFRLLDQVGIDVMAYVAANLYDAIPDDESRDVYRQNDLTQKLVAAGKLGKKVGQGFYKEVRQNGKREFWAL
DLQTLEYVPPQGTAAVDELIGAARKIKSLPERLRFILGRAEEGDRGAQLVAAAVYPMMAYAARRLPEIADSVADVDNAMR
WGFAHEQGPFQLWQAMGIAETASRMRAFGESLPAWVDQLIATDGRFYGEIDGTPAAYNVATGRLEPIQRDPRAIDLAALK
AAGRELHGNESASVIDLGDGVLCFELHSKANTIGGQVIEMLIKALDELDQGPWVGMVVGNQGPRFSAGLDLNDVGAAVMT
GAWDDIDEYAALVQQTFRRMRDSAKPIVSAPFGQTLGGGVELSMHSAASVAAAETYMGFVEFGVGVIPAWGGCTEMNRRI
IAAAVRNGSDPLKAFQQVFETIALAKVATSAHEAKELGLLRPTDRIVFNPDYLIGEAKREVLRLVAEGYTPAVTAKPCYA
LGRDGLAAARIAIYQMREGGFATPYDAVIADKLAYVLCGGELSSPQWVDDVYMHALERAMVLELLKDPRTQARARHMLEH
GKPLRN

Sequences:

>Translated_806_residues
MTYQIKRVGVIGAGTMGAAIAALVAGTGIPVILLDVPPSSLTAEEEAKGLTLNHPQVRNRIVQQGFERMRKARPSNLYSE
RTAELITLGNTEDDFHRLAECDWIVEAIVEQIGPKQSLMARLEEVRKPHAIVTTNTSGIPIRIIAEGRSEAFRRHFFGSH
FFNPPRYLRLLEIIPGDDADPAVVAAFRQFAEERLGKGVVICKDRPNFIGNRIFVYAGQVLINYALQHGYRVEEVDALTG
PLIGRPNTASFRLLDQVGIDVMAYVAANLYDAIPDDESRDVYRQNDLTQKLVAAGKLGKKVGQGFYKEVRQNGKREFWAL
DLQTLEYVPPQGTAAVDELIGAARKIKSLPERLRFILGRAEEGDRGAQLVAAAVYPMMAYAARRLPEIADSVADVDNAMR
WGFAHEQGPFQLWQAMGIAETASRMRAFGESLPAWVDQLIATDGRFYGEIDGTPAAYNVATGRLEPIQRDPRAIDLAALK
AAGRELHGNESASVIDLGDGVLCFELHSKANTIGGQVIEMLIKALDELDQGPWVGMVVGNQGPRFSAGLDLNDVGAAVMT
GAWDDIDEYAALVQQTFRRMRDSAKPIVSAPFGQTLGGGVELSMHSAASVAAAETYMGFVEFGVGVIPAWGGCTEMNRRI
IAAAVRNGSDPLKAFQQVFETIALAKVATSAHEAKELGLLRPTDRIVFNPDYLIGEAKREVLRLVAEGYTPAVTAKPCYA
LGRDGLAAARIAIYQMREGGFATPYDAVIADKLAYVLCGGELSSPQWVDDVYMHALERAMVLELLKDPRTQARARHMLEH
GKPLRN
>Mature_805_residues
TYQIKRVGVIGAGTMGAAIAALVAGTGIPVILLDVPPSSLTAEEEAKGLTLNHPQVRNRIVQQGFERMRKARPSNLYSER
TAELITLGNTEDDFHRLAECDWIVEAIVEQIGPKQSLMARLEEVRKPHAIVTTNTSGIPIRIIAEGRSEAFRRHFFGSHF
FNPPRYLRLLEIIPGDDADPAVVAAFRQFAEERLGKGVVICKDRPNFIGNRIFVYAGQVLINYALQHGYRVEEVDALTGP
LIGRPNTASFRLLDQVGIDVMAYVAANLYDAIPDDESRDVYRQNDLTQKLVAAGKLGKKVGQGFYKEVRQNGKREFWALD
LQTLEYVPPQGTAAVDELIGAARKIKSLPERLRFILGRAEEGDRGAQLVAAAVYPMMAYAARRLPEIADSVADVDNAMRW
GFAHEQGPFQLWQAMGIAETASRMRAFGESLPAWVDQLIATDGRFYGEIDGTPAAYNVATGRLEPIQRDPRAIDLAALKA
AGRELHGNESASVIDLGDGVLCFELHSKANTIGGQVIEMLIKALDELDQGPWVGMVVGNQGPRFSAGLDLNDVGAAVMTG
AWDDIDEYAALVQQTFRRMRDSAKPIVSAPFGQTLGGGVELSMHSAASVAAAETYMGFVEFGVGVIPAWGGCTEMNRRII
AAAVRNGSDPLKAFQQVFETIALAKVATSAHEAKELGLLRPTDRIVFNPDYLIGEAKREVLRLVAEGYTPAVTAKPCYAL
GRDGLAAARIAIYQMREGGFATPYDAVIADKLAYVLCGGELSSPQWVDDVYMHALERAMVLELLKDPRTQARARHMLEHG
KPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=304, Percent_Identity=32.5657894736842, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI296179427, Length=320, Percent_Identity=30.9375, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI20127408, Length=378, Percent_Identity=29.1005291005291, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI261878539, Length=312, Percent_Identity=27.5641025641026, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI68989263, Length=312, Percent_Identity=27.5641025641026, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1787661, Length=310, Percent_Identity=32.9032258064516, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1790281, Length=404, Percent_Identity=26.4851485148515, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1788682, Length=283, Percent_Identity=29.3286219081272, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17553560, Length=310, Percent_Identity=31.2903225806452, Blast_Score=136, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17549919, Length=313, Percent_Identity=29.3929712460064, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17508951, Length=311, Percent_Identity=30.5466237942122, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17508953, Length=311, Percent_Identity=30.5466237942122, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25144276, Length=311, Percent_Identity=30.5466237942122, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17558304, Length=334, Percent_Identity=28.7425149700599, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71985923, Length=318, Percent_Identity=28.3018867924528, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71985930, Length=324, Percent_Identity=28.3950617283951, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17563036, Length=303, Percent_Identity=27.7227722772277, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19921000, Length=309, Percent_Identity=34.3042071197411, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583077, Length=309, Percent_Identity=34.3042071197411, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583079, Length=309, Percent_Identity=34.3042071197411, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 88107; Mature: 87976

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQIKRVGVIGAGTMGAAIAALVAGTGIPVILLDVPPSSLTAEEEAKGLTLNHPQVRNR
CCEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHCCCCCCCCHHHHHH
IVQQGFERMRKARPSNLYSERTAELITLGNTEDDFHRLAECDWIVEAIVEQIGPKQSLMA
HHHHHHHHHHHCCCCCHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RLEEVRKPHAIVTTNTSGIPIRIIAEGRSEAFRRHFFGSHFFNPPRYLRLLEIIPGDDAD
HHHHHCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
PAVVAAFRQFAEERLGKGVVICKDRPNFIGNRIFVYAGQVLINYALQHGYRVEEVDALTG
HHHHHHHHHHHHHHHCCCEEEECCCCCHHCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHC
PLIGRPNTASFRLLDQVGIDVMAYVAANLYDAIPDDESRDVYRQNDLTQKLVAAGKLGKK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VGQGFYKEVRQNGKREFWALDLQTLEYVPPQGTAAVDELIGAARKIKSLPERLRFILGRA
HHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EEGDRGAQLVAAAVYPMMAYAARRLPEIADSVADVDNAMRWGFAHEQGPFQLWQAMGIAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
TASRMRAFGESLPAWVDQLIATDGRFYGEIDGTPAAYNVATGRLEPIQRDPRAIDLAALK
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCCCCCCCHHHHHHHH
AAGRELHGNESASVIDLGDGVLCFELHSKANTIGGQVIEMLIKALDELDQGPWVGMVVGN
HHCHHCCCCCCCCEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
QGPRFSAGLDLNDVGAAVMTGAWDDIDEYAALVQQTFRRMRDSAKPIVSAPFGQTLGGGV
CCCCEECCCCHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCE
ELSMHSAASVAAAETYMGFVEFGVGVIPAWGGCTEMNRRIIAAAVRNGSDPLKAFQQVFE
EEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TIALAKVATSAHEAKELGLLRPTDRIVFNPDYLIGEAKREVLRLVAEGYTPAVTAKPCYA
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LGRDGLAAARIAIYQMREGGFATPYDAVIADKLAYVLCGGELSSPQWVDDVYMHALERAM
HCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHH
VLELLKDPRTQARARHMLEHGKPLRN
HHHHHHCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TYQIKRVGVIGAGTMGAAIAALVAGTGIPVILLDVPPSSLTAEEEAKGLTLNHPQVRNR
CEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHCCCCCCCCHHHHHH
IVQQGFERMRKARPSNLYSERTAELITLGNTEDDFHRLAECDWIVEAIVEQIGPKQSLMA
HHHHHHHHHHHCCCCCHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RLEEVRKPHAIVTTNTSGIPIRIIAEGRSEAFRRHFFGSHFFNPPRYLRLLEIIPGDDAD
HHHHHCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
PAVVAAFRQFAEERLGKGVVICKDRPNFIGNRIFVYAGQVLINYALQHGYRVEEVDALTG
HHHHHHHHHHHHHHHCCCEEEECCCCCHHCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHC
PLIGRPNTASFRLLDQVGIDVMAYVAANLYDAIPDDESRDVYRQNDLTQKLVAAGKLGKK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VGQGFYKEVRQNGKREFWALDLQTLEYVPPQGTAAVDELIGAARKIKSLPERLRFILGRA
HHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EEGDRGAQLVAAAVYPMMAYAARRLPEIADSVADVDNAMRWGFAHEQGPFQLWQAMGIAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
TASRMRAFGESLPAWVDQLIATDGRFYGEIDGTPAAYNVATGRLEPIQRDPRAIDLAALK
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCCCCCCCHHHHHHHH
AAGRELHGNESASVIDLGDGVLCFELHSKANTIGGQVIEMLIKALDELDQGPWVGMVVGN
HHCHHCCCCCCCCEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
QGPRFSAGLDLNDVGAAVMTGAWDDIDEYAALVQQTFRRMRDSAKPIVSAPFGQTLGGGV
CCCCEECCCCHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCE
ELSMHSAASVAAAETYMGFVEFGVGVIPAWGGCTEMNRRIIAAAVRNGSDPLKAFQQVFE
EEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TIALAKVATSAHEAKELGLLRPTDRIVFNPDYLIGEAKREVLRLVAEGYTPAVTAKPCYA
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LGRDGLAAARIAIYQMREGGFATPYDAVIADKLAYVLCGGELSSPQWVDDVYMHALERAM
HCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHH
VLELLKDPRTQARARHMLEHGKPLRN
HHHHHHCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]