Click here to switch to the map view.

The map label for this gene is rsbRA [H]

Identifier: 222526669

GI number: 222526669

Start: 4287286

End: 4288413

Strand: Direct

Name: rsbRA [H]

Synonym: Chy400_3438

Alternate gene names: 222526669

Gene position: 4287286-4288413 (Clockwise)

Preceding gene: 222526668

Following gene: 222526670

Centisome position: 81.37

GC content: 56.91

Gene sequence:

>1128_bases
ATGCTGGATACTTTACCGTTGCCGACCGCCTATGCACCTGATGGAGGGTCGGTGCAGTGTAATCGTTTATGGCTGGAGTT
GAGTGATGGCGGAGGAGTTGCGAGAGACCTGGTGGAAGCCTGTGCACAGATTCTGGCCTGGAACGAGTCTGAGGTTGCAG
CAGCCAGGCAATGGATTGCGACACTCTCTGCCGGCGATCCGCCGCTGCAACTGGCAGCGCCGTTGCGCCGTGACCCGACA
CGTCATGTTCAGATCATGATCCTACGCAGTGAGGCCGCATTGACCGCTCAGGTTGTCGAAGTGACAGCGCTGTTGACTGC
GCAACGTGCAGCTCAGCATCAGCTTGATGTGATTTTGAGCGCACTGGACAGTCTGGAAGAGGGCTTTCTGCTGCTTGATA
AAGATGATCGGATCGTCTTCTGCAATCGACGCTACCGTGAATTGTATGCCATCAGTGCTGATCTCGTGACACCTGGCCGT
CCATTTGCCGAAATGATTCGGATTGGCGCCGAGCGAGGGCAGTACGCTGAAGCGATTGGGCGGGTTGACGAGTGGGTTGC
GGAGCGGTTGCGGAAACATGCCGCACTTGAACCGGTCGAGCAACATCTCGCCGATGGGCGCTGGATTCGGATTGTTGAGC
GAAGAACTGCCGATGGGGGGATCGTCGGATTGCGGATTGACATCACTGAATTGAAGAAGGCAGAGGAGCTGCGCCGGCAA
CTGGCAGTGCGCGAAGAGGTCATTGCAACCCAGGCTGCATTGCTGGCTGAGCTGTCGACACCCTTACTCGAAGTTGCCAC
ACGAGTACTGTTGGCACCAATGGTCGGCGCATTCGATAGTGCACGGGTGGCGACGTTAATCGAGTCACTCTTACAGGCAG
TGCAGCGCCGACAGGTACGCATTGTTGTGCTCGATGTAACCGGGGTGCCGGTGATTGATACGCAGGTTGCGCATGCTATT
TTGCAGTGCGCTACGTCGTTGCGCTTGCTCGGTGCTCAGTTGGTGATCACCGGGATCCGTCCTGATGTTGCGCAGACTCT
GGTTGCGCTTGGTGTTGATCTAAGCACGATTGTGACCCGTGCCGATCTACGTGATGGAGTGCAGTATGCGTTGCGGCAGA
GCAGGTGA

Upstream 100 bases:

>100_bases
CGCGGATCGTGGATGGTGCAGCTTTATAAGTTCATGTCAGGTGGGTTATAATGCAAGCGTATTTTCACCGGTTCTCAGGC
AAGTTAGCGAGAGCAAAGCA

Downstream 100 bases:

>100_bases
GGTGTCGCACACCCAGGATGTCTCTATCCGCAGGTGAGAGCGCTGTGTGTGGCAGTGTTTACGTAAACTATAACCCAAGT
TGCTACCTTTGCCACCACAG

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MLDTLPLPTAYAPDGGSVQCNRLWLELSDGGGVARDLVEACAQILAWNESEVAAARQWIATLSAGDPPLQLAAPLRRDPT
RHVQIMILRSEAALTAQVVEVTALLTAQRAAQHQLDVILSALDSLEEGFLLLDKDDRIVFCNRRYRELYAISADLVTPGR
PFAEMIRIGAERGQYAEAIGRVDEWVAERLRKHAALEPVEQHLADGRWIRIVERRTADGGIVGLRIDITELKKAEELRRQ
LAVREEVIATQAALLAELSTPLLEVATRVLLAPMVGAFDSARVATLIESLLQAVQRRQVRIVVLDVTGVPVIDTQVAHAI
LQCATSLRLLGAQLVITGIRPDVAQTLVALGVDLSTIVTRADLRDGVQYALRQSR

Sequences:

>Translated_375_residues
MLDTLPLPTAYAPDGGSVQCNRLWLELSDGGGVARDLVEACAQILAWNESEVAAARQWIATLSAGDPPLQLAAPLRRDPT
RHVQIMILRSEAALTAQVVEVTALLTAQRAAQHQLDVILSALDSLEEGFLLLDKDDRIVFCNRRYRELYAISADLVTPGR
PFAEMIRIGAERGQYAEAIGRVDEWVAERLRKHAALEPVEQHLADGRWIRIVERRTADGGIVGLRIDITELKKAEELRRQ
LAVREEVIATQAALLAELSTPLLEVATRVLLAPMVGAFDSARVATLIESLLQAVQRRQVRIVVLDVTGVPVIDTQVAHAI
LQCATSLRLLGAQLVITGIRPDVAQTLVALGVDLSTIVTRADLRDGVQYALRQSR
>Mature_375_residues
MLDTLPLPTAYAPDGGSVQCNRLWLELSDGGGVARDLVEACAQILAWNESEVAAARQWIATLSAGDPPLQLAAPLRRDPT
RHVQIMILRSEAALTAQVVEVTALLTAQRAAQHQLDVILSALDSLEEGFLLLDKDDRIVFCNRRYRELYAISADLVTPGR
PFAEMIRIGAERGQYAEAIGRVDEWVAERLRKHAALEPVEQHLADGRWIRIVERRTADGGIVGLRIDITELKKAEELRRQ
LAVREEVIATQAALLAELSTPLLEVATRVLLAPMVGAFDSARVATLIESLLQAVQRRQVRIVVLDVTGVPVIDTQVAHAI
LQCATSLRLLGAQLVITGIRPDVAQTLVALGVDLSTIVTRADLRDGVQYALRQSR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 41070; Mature: 41070

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTLPLPTAYAPDGGSVQCNRLWLELSDGGGVARDLVEACAQILAWNESEVAAARQWIA
CCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TLSAGDPPLQLAAPLRRDPTRHVQIMILRSEAALTAQVVEVTALLTAQRAAQHQLDVILS
HHCCCCCCHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDSLEEGFLLLDKDDRIVFCNRRYRELYAISADLVTPGRPFAEMIRIGAERGQYAEAIG
HHHHHHCCEEEEECCCCEEEECCHHHHHHHEECCCCCCCCCHHHHHHHHHCCCHHHHHHH
RVDEWVAERLRKHAALEPVEQHLADGRWIRIVERRTADGGIVGLRIDITELKKAEELRRQ
HHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEEECCCCCEEEEEEEHHHHHHHHHHHHH
LAVREEVIATQAALLAELSTPLLEVATRVLLAPMVGAFDSARVATLIESLLQAVQRRQVR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEE
IVVLDVTGVPVIDTQVAHAILQCATSLRLLGAQLVITGIRPDVAQTLVALGVDLSTIVTR
EEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCHHHHHHH
ADLRDGVQYALRQSR
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDTLPLPTAYAPDGGSVQCNRLWLELSDGGGVARDLVEACAQILAWNESEVAAARQWIA
CCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TLSAGDPPLQLAAPLRRDPTRHVQIMILRSEAALTAQVVEVTALLTAQRAAQHQLDVILS
HHCCCCCCHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDSLEEGFLLLDKDDRIVFCNRRYRELYAISADLVTPGRPFAEMIRIGAERGQYAEAIG
HHHHHHCCEEEEECCCCEEEECCHHHHHHHEECCCCCCCCCHHHHHHHHHCCCHHHHHHH
RVDEWVAERLRKHAALEPVEQHLADGRWIRIVERRTADGGIVGLRIDITELKKAEELRRQ
HHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEEECCCCCEEEEEEEHHHHHHHHHHHHH
LAVREEVIATQAALLAELSTPLLEVATRVLLAPMVGAFDSARVATLIESLLQAVQRRQVR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEE
IVVLDVTGVPVIDTQVAHAILQCATSLRLLGAQLVITGIRPDVAQTLVALGVDLSTIVTR
EEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCHHHHHHH
ADLRDGVQYALRQSR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]