Click here to switch to the map view.

The map label for this gene is yycF [H]

Identifier: 222526656

GI number: 222526656

Start: 4267193

End: 4267870

Strand: Reverse

Name: yycF [H]

Synonym: Chy400_3425

Alternate gene names: 222526656

Gene position: 4267870-4267193 (Counterclockwise)

Preceding gene: 222526657

Following gene: 222526654

Centisome position: 81.0

GC content: 54.13

Gene sequence:

>678_bases
ATGAACCAGCGCATCCTTATCGTCGACGATGATCCGGGAATTGTTGCTGCGATCACGCCTTCACTGCGGGCACAGGGATA
CAACATTGCTATCGCGCACGACGGCGAGAGCGCATTGCAGAAGTTTAGTCACCTTGTTCCCGATCTGGTGCTCCTCGATC
TCGTCATGCCATCGCTGCACGGCATTGCTGTCTGTCAGCGAATCCGCCAGCAACGTTCAACCCCGATCATTGTGATTAGT
GTGAAAGGTGCCGAAGCGGATATTGTCACCGCCCTTGATAACGGTGCCGATGATTACCTGGTTAAGCCCTTCCGGTTGAG
CGAACTGCTGGCCCGCATCCGGGCAGTCTTACGTCGTGGCCGTAGTGAACAGACGGTTATTCAATGTGCCGATCTGGTGA
TTGATACAAACCGCCGTATTGTGCAGCGTCAGGGGGAGACGATCAATCTAACGCCGATAGAATACGCGGTACTGGCCGAA
CTAGTCGCGCACCGCGATGGTGTCGTCACTGCGCGACAGATAGTGCAGAGAGTATGGGGGCCACAGTATACCGATTCAAC
TGACTACGTCAAAGGGGTTATTCGCCGTTTACGGGTGAAGATTGAACCAGACCCTTCGCATCCGCGCTACATCATTACCG
AGCCACATGTCGGTTATCGATTCAATGATGGTGGGTAG

Upstream 100 bases:

>100_bases
AACGACCGGGAGGTGGCAGCGTATTTCGGATTACCCTACCGTTCATCAACGACCAACCAACTGCGTGGTGCCCGTTGGAG
TTTCACGGAGGAGAGCAGGT

Downstream 100 bases:

>100_bases
AAGGCTACCGCATCGCCCACTTGTCGTGCCCATGACCGGCGAGCAACGTACCATCATACGCCTGGTCGCTCGTGGGTTGT
CGTCGGCGTGCGGTAGGGGA

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MNQRILIVDDDPGIVAAITPSLRAQGYNIAIAHDGESALQKFSHLVPDLVLLDLVMPSLHGIAVCQRIRQQRSTPIIVIS
VKGAEADIVTALDNGADDYLVKPFRLSELLARIRAVLRRGRSEQTVIQCADLVIDTNRRIVQRQGETINLTPIEYAVLAE
LVAHRDGVVTARQIVQRVWGPQYTDSTDYVKGVIRRLRVKIEPDPSHPRYIITEPHVGYRFNDGG

Sequences:

>Translated_225_residues
MNQRILIVDDDPGIVAAITPSLRAQGYNIAIAHDGESALQKFSHLVPDLVLLDLVMPSLHGIAVCQRIRQQRSTPIIVIS
VKGAEADIVTALDNGADDYLVKPFRLSELLARIRAVLRRGRSEQTVIQCADLVIDTNRRIVQRQGETINLTPIEYAVLAE
LVAHRDGVVTARQIVQRVWGPQYTDSTDYVKGVIRRLRVKIEPDPSHPRYIITEPHVGYRFNDGG
>Mature_225_residues
MNQRILIVDDDPGIVAAITPSLRAQGYNIAIAHDGESALQKFSHLVPDLVLLDLVMPSLHGIAVCQRIRQQRSTPIIVIS
VKGAEADIVTALDNGADDYLVKPFRLSELLARIRAVLRRGRSEQTVIQCADLVIDTNRRIVQRQGETINLTPIEYAVLAE
LVAHRDGVVTARQIVQRVWGPQYTDSTDYVKGVIRRLRVKIEPDPSHPRYIITEPHVGYRFNDGG

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=37.7272727272727, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=36.2445414847162, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=33.4801762114537, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=34.841628959276, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=33.1818181818182, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI2367329, Length=221, Percent_Identity=36.6515837104072, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=31.8385650224215, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=203, Percent_Identity=33.9901477832512, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=28.6995515695067, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=28.8888888888889, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=27.0742358078603, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=27.3127753303965, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790860, Length=211, Percent_Identity=27.4881516587678, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=25.6521739130435, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=37.037037037037, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790437, Length=122, Percent_Identity=35.2459016393443, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787487, Length=104, Percent_Identity=33.6538461538462, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1790299, Length=121, Percent_Identity=28.099173553719, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=106, Percent_Identity=33.9622641509434, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25097; Mature: 25097

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRILIVDDDPGIVAAITPSLRAQGYNIAIAHDGESALQKFSHLVPDLVLLDLVMPSLH
CCCEEEEEECCCCEEEEECCCHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
GIAVCQRIRQQRSTPIIVISVKGAEADIVTALDNGADDYLVKPFRLSELLARIRAVLRRG
HHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHCC
RSEQTVIQCADLVIDTNRRIVQRQGETINLTPIEYAVLAELVAHRDGVVTARQIVQRVWG
CCHHHHHHHHHHHHCCCHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
PQYTDSTDYVKGVIRRLRVKIEPDPSHPRYIITEPHVGYRFNDGG
CCCCCCHHHHHHHHHHHEEEECCCCCCCEEEEECCCCCEEECCCC
>Mature Secondary Structure
MNQRILIVDDDPGIVAAITPSLRAQGYNIAIAHDGESALQKFSHLVPDLVLLDLVMPSLH
CCCEEEEEECCCCEEEEECCCHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
GIAVCQRIRQQRSTPIIVISVKGAEADIVTALDNGADDYLVKPFRLSELLARIRAVLRRG
HHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHCC
RSEQTVIQCADLVIDTNRRIVQRQGETINLTPIEYAVLAELVAHRDGVVTARQIVQRVWG
CCHHHHHHHHHHHHCCCHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
PQYTDSTDYVKGVIRRLRVKIEPDPSHPRYIITEPHVGYRFNDGG
CCCCCCHHHHHHHHHHHEEEECCCCCCCEEEEECCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]