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The map label for this gene is engA

Identifier: 222526586

GI number: 222526586

Start: 4176649

End: 4177998

Strand: Direct

Name: engA

Synonym: Chy400_3354

Alternate gene names: 222526586

Gene position: 4176649-4177998 (Clockwise)

Preceding gene: 222526583

Following gene: 222526587

Centisome position: 79.27

GC content: 54.74

Gene sequence:

>1350_bases
ATGACAAAACCGATTGTGGCCATTGTTGGCCGCCCAAACGTTGGTAAATCGACATTTTTCAACCGCTTAATTGGCGAGCG
GCGCGCGATTGTCGAGGACCTGCCCGGCACGACGCGCGACCGTCTCTATGGTGATACCTTTTGGAATGGGCGCGAGTTCA
CCGTCGTCGATACGGCAGGTGTCCTCTTCGGTGGTGAAGATCCGAACCTGCCCGAAGCCGAGATTGCCCGTCGTACCCGT
GCTCAGGCTGAACACGCGATTGCTGAGGCAGACGCGATCATCTTTATTGTTGACGGTCGTGACGGTCTGACTGCCGCTGA
TTCTGATGTTGCCGACGTGTTACGCACCACGTCGAAACCGGTTGTGCTGGCCGTCAACAAGTGTGACAGTCAGGAACGCA
TGCTCGATGCGGTTGAGTTTTATGCGCTCAATCTTGGCGAACCGATCCCGATGAGCGCATTTCATGGCCTGGGAACGGGG
GATGTGCTCGACCGCCTGACCGAGTATCTGCCGCCAAAGACCTTTACCCAAGAGGAAGAGCGCCATCTACGGATTGCGAT
TGTCGGTCGACCAAATGTAGGCAAGTCTTCGCTGCTGAACCGTCTGCTCGGTCAAGAGCGCAGCGTCGTAAGCTCGATTC
CAGGTACTACACGCGATCCTATCGATACCACCATTACCTATCACGGTGAACCGATTACACTGATCGATACTGCCGGTATT
CGGCGGGCCGGAAAGATCGAGCGTGGTATTGAGAAATATAGCGTGCTGCGCACATTGCGGGCAATTGAACGATGCGACGT
AGCGCTGCTGCTGATCGATGCGACTGAAGGGGTAACAGCCCAGGATACCCACATTGCCGGTATGGTGGTTGAGGCCAAGA
AAGGCTTGATCCTGGTCGTCAATAAGTGGGACGCCATTGAGAAAGACTCGCATACCTACTACGCATTCCAGGATCAGGTT
CGCGAGGCATTTAAGTTTGTCGATTATGCACCGATTGTTTTTGTGTCGGCATTGACCGGTCAGCGCGTCTCGCACCTGCT
CGACTATGCGCGTGAAGTGTATGTCCAGCGGCAGAAGCGAGTGCCGACCAGCGAGCTGAACAACTTCTTGCGGGAAGTGA
TGTTGCAACAGCCACCGATGGCGGTCAAGAAGGGAGCACATCTGCGCCTGTACTATGCAGTGCAACCACAAACCGAGCCG
CCGGTTTTTCTCTTCTTTGCCAACGATGGTGAGTTAGTCCACTGGTCGTATGCTCGCTACCTCGAAAATCGTTTGCGCGA
ACGTTATGGTTTTCAGGGCACGCCAATCGTGATCGTGTTCCGTTCGCGTGAACGAAAAGAGGAACGTTGA

Upstream 100 bases:

>100_bases
CCCTTCTACGACAACAATCGCAAACCCTGACCACTTCGTTTGCGATCCCTACTATAATAGAAGGCAGAGGACGCACCCAT
ACTGGCGTCCAGGAGGAGTT

Downstream 100 bases:

>100_bases
ACGTTGTTTCTATAGGCTTGTATCCGCTCATGATCATTGCTTAACGTCTATTGCAAGGCGGCATGTTGTTGATCGTTGCA
GGTCAACACGGCTGCCTTTC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTKPIVAIVGRPNVGKSTFFNRLIGERRAIVEDLPGTTRDRLYGDTFWNGREFTVVDTAGVLFGGEDPNLPEAEIARRTR
AQAEHAIAEADAIIFIVDGRDGLTAADSDVADVLRTTSKPVVLAVNKCDSQERMLDAVEFYALNLGEPIPMSAFHGLGTG
DVLDRLTEYLPPKTFTQEEERHLRIAIVGRPNVGKSSLLNRLLGQERSVVSSIPGTTRDPIDTTITYHGEPITLIDTAGI
RRAGKIERGIEKYSVLRTLRAIERCDVALLLIDATEGVTAQDTHIAGMVVEAKKGLILVVNKWDAIEKDSHTYYAFQDQV
REAFKFVDYAPIVFVSALTGQRVSHLLDYAREVYVQRQKRVPTSELNNFLREVMLQQPPMAVKKGAHLRLYYAVQPQTEP
PVFLFFANDGELVHWSYARYLENRLRERYGFQGTPIVIVFRSRERKEER

Sequences:

>Translated_449_residues
MTKPIVAIVGRPNVGKSTFFNRLIGERRAIVEDLPGTTRDRLYGDTFWNGREFTVVDTAGVLFGGEDPNLPEAEIARRTR
AQAEHAIAEADAIIFIVDGRDGLTAADSDVADVLRTTSKPVVLAVNKCDSQERMLDAVEFYALNLGEPIPMSAFHGLGTG
DVLDRLTEYLPPKTFTQEEERHLRIAIVGRPNVGKSSLLNRLLGQERSVVSSIPGTTRDPIDTTITYHGEPITLIDTAGI
RRAGKIERGIEKYSVLRTLRAIERCDVALLLIDATEGVTAQDTHIAGMVVEAKKGLILVVNKWDAIEKDSHTYYAFQDQV
REAFKFVDYAPIVFVSALTGQRVSHLLDYAREVYVQRQKRVPTSELNNFLREVMLQQPPMAVKKGAHLRLYYAVQPQTEP
PVFLFFANDGELVHWSYARYLENRLRERYGFQGTPIVIVFRSRERKEER
>Mature_448_residues
TKPIVAIVGRPNVGKSTFFNRLIGERRAIVEDLPGTTRDRLYGDTFWNGREFTVVDTAGVLFGGEDPNLPEAEIARRTRA
QAEHAIAEADAIIFIVDGRDGLTAADSDVADVLRTTSKPVVLAVNKCDSQERMLDAVEFYALNLGEPIPMSAFHGLGTGD
VLDRLTEYLPPKTFTQEEERHLRIAIVGRPNVGKSSLLNRLLGQERSVVSSIPGTTRDPIDTTITYHGEPITLIDTAGIR
RAGKIERGIEKYSVLRTLRAIERCDVALLLIDATEGVTAQDTHIAGMVVEAKKGLILVVNKWDAIEKDSHTYYAFQDQVR
EAFKFVDYAPIVFVSALTGQRVSHLLDYAREVYVQRQKRVPTSELNNFLREVMLQQPPMAVKKGAHLRLYYAVQPQTEPP
VFLFFANDGELVHWSYARYLENRLRERYGFQGTPIVIVFRSRERKEER

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Homo sapiens, GI193082991, Length=133, Percent_Identity=33.0827067669173, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI193082988, Length=134, Percent_Identity=32.8358208955224, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082120, Length=474, Percent_Identity=39.873417721519, Blast_Score=315, Evalue=5e-87,
Organism=Escherichia coli, GI1788919, Length=175, Percent_Identity=34.8571428571429, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=43.010752688172, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17507259, Length=135, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=184, Percent_Identity=34.2391304347826, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45550813, Length=144, Percent_Identity=36.8055555555556, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_CHLAA (A9WHH9)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001636694.1
- ProteinModelPortal:   A9WHH9
- SMR:   A9WHH9
- GeneID:   5827580
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_3106
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 50514; Mature: 50383

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPIVAIVGRPNVGKSTFFNRLIGERRAIVEDLPGTTRDRLYGDTFWNGREFTVVDTAG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEECCC
VLFGGEDPNLPEAEIARRTRAQAEHAIAEADAIIFIVDGRDGLTAADSDVADVLRTTSKP
EEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCC
VVLAVNKCDSQERMLDAVEFYALNLGEPIPMSAFHGLGTGDVLDRLTEYLPPKTFTQEEE
EEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCC
RHLRIAIVGRPNVGKSSLLNRLLGQERSVVSSIPGTTRDPIDTTITYHGEPITLIDTAGI
CEEEEEEEECCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECCCC
RRAGKIERGIEKYSVLRTLRAIERCDVALLLIDATEGVTAQDTHIAGMVVEAKKGLILVV
CHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEEE
NKWDAIEKDSHTYYAFQDQVREAFKFVDYAPIVFVSALTGQRVSHLLDYAREVYVQRQKR
ECCCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPTSELNNFLREVMLQQPPMAVKKGAHLRLYYAVQPQTEPPVFLFFANDGELVHWSYARY
CCHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCCCEEEEECCCCCEEEHHHHHH
LENRLRERYGFQGTPIVIVFRSRERKEER
HHHHHHHHHCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TKPIVAIVGRPNVGKSTFFNRLIGERRAIVEDLPGTTRDRLYGDTFWNGREFTVVDTAG
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEECCC
VLFGGEDPNLPEAEIARRTRAQAEHAIAEADAIIFIVDGRDGLTAADSDVADVLRTTSKP
EEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCC
VVLAVNKCDSQERMLDAVEFYALNLGEPIPMSAFHGLGTGDVLDRLTEYLPPKTFTQEEE
EEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCC
RHLRIAIVGRPNVGKSSLLNRLLGQERSVVSSIPGTTRDPIDTTITYHGEPITLIDTAGI
CEEEEEEEECCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECCCC
RRAGKIERGIEKYSVLRTLRAIERCDVALLLIDATEGVTAQDTHIAGMVVEAKKGLILVV
CHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEEE
NKWDAIEKDSHTYYAFQDQVREAFKFVDYAPIVFVSALTGQRVSHLLDYAREVYVQRQKR
ECCCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPTSELNNFLREVMLQQPPMAVKKGAHLRLYYAVQPQTEPPVFLFFANDGELVHWSYARY
CCHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCCCEEEEECCCCCEEEHHHHHH
LENRLRERYGFQGTPIVIVFRSRERKEER
HHHHHHHHHCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA