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The map label for this gene is trmB

Identifier: 222526581

GI number: 222526581

Start: 4173399

End: 4174073

Strand: Direct

Name: trmB

Synonym: Chy400_3349

Alternate gene names: 222526581

Gene position: 4173399-4174073 (Clockwise)

Preceding gene: 222526580

Following gene: 222526582

Centisome position: 79.21

GC content: 58.07

Gene sequence:

>675_bases
ATGGGAAGAGGTCGCTATCCAGCTCGCCTGTACGTTACTGCGCCACCACCTGAGATTGCGGCGCGCTACTATCGTTCGTG
GCCGGCAAAAGAACTTTACCATACGCCGGAACACTTTCCACCCGTGAGCGCGGAGGGGTTGTTTGGCTACAATGCACCAC
TGACGCTCGAATTTGGCTGTGCAACTGGTGAGTACTTGTGTGCACTGGCAGCCGCCCAGCCATCCTCTTGCTTTGTGGGC
ATCGATATTGTTGCCAAGCCGCTCTACCGCGCCGTTGAGCGGGCCGTGGCAGGAAATCTCTCGAACATCCTGTTCATTCA
TGCCGATGCCCGGCTTATTTATCAGCGCATCCCTACTGCCGCATTGCACAGCATTATTCTCCACTTTCCACCACCACTCC
TGCGTAATCGTCAGCGCAATCAGTTACTCGTTTCGCCGCAATTGCTGGAGTGTGCGGCGCGCACGCTCGTTCCTGGCGGC
TATCTCAGCTTTCTCACCGATCATCCGGCCCTCTTCGCCTTGATGCAAGAACTCTTACCCGCCTTTCCTGCGCTGCGTGC
CACACCGGCTTCGGTAGAGGAGCTGGCAGTCTTCGAGTCGCATTACCATCGCCGCTGGGCCGCTCGTGGCCGCACGATTA
GCGGTCTACGGATCGAGCGGGTGATGGAGGACTAG

Upstream 100 bases:

>100_bases
TGCGTTTGCAGAGGTGATCACCAAAACAACATTCGGCTATCCCTAAAGGAATCACCTCCAACCCTATTTTCTATTTTCTA
CGTTCTATTTTCTAAATCCT

Downstream 100 bases:

>100_bases
GGGAGAGGAAATAGGAAATAGGAAATAGAAAATAGGGACGAGGAGTGAGGGAGGAGGGTAAGTTCTAGAGTTTGTAAAGC
TGTCCCGTCGTAATGGCCTG

Product: putative methyltransferase

Products: NA

Alternate protein names: tRNA(m7G46)-methyltransferase

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MGRGRYPARLYVTAPPPEIAARYYRSWPAKELYHTPEHFPPVSAEGLFGYNAPLTLEFGCATGEYLCALAAAQPSSCFVG
IDIVAKPLYRAVERAVAGNLSNILFIHADARLIYQRIPTAALHSIILHFPPPLLRNRQRNQLLVSPQLLECAARTLVPGG
YLSFLTDHPALFALMQELLPAFPALRATPASVEELAVFESHYHRRWAARGRTISGLRIERVMED

Sequences:

>Translated_224_residues
MGRGRYPARLYVTAPPPEIAARYYRSWPAKELYHTPEHFPPVSAEGLFGYNAPLTLEFGCATGEYLCALAAAQPSSCFVG
IDIVAKPLYRAVERAVAGNLSNILFIHADARLIYQRIPTAALHSIILHFPPPLLRNRQRNQLLVSPQLLECAARTLVPGG
YLSFLTDHPALFALMQELLPAFPALRATPASVEELAVFESHYHRRWAARGRTISGLRIERVMED
>Mature_223_residues
GRGRYPARLYVTAPPPEIAARYYRSWPAKELYHTPEHFPPVSAEGLFGYNAPLTLEFGCATGEYLCALAAAQPSSCFVGI
DIVAKPLYRAVERAVAGNLSNILFIHADARLIYQRIPTAALHSIILHFPPPLLRNRQRNQLLVSPQLLECAARTLVPGGY
LSFLTDHPALFALMQELLPAFPALRATPASVEELAVFESHYHRRWAARGRTISGLRIERVMED

Specific function: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA

COG id: COG0220

COG function: function code R; Predicted S-adenosylmethionine-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TrmB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMB_CHLAA (A9WHH4)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001636689.1
- ProteinModelPortal:   A9WHH4
- GeneID:   5827575
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_3101
- HOGENOM:   HBG403974
- OMA:   ITYIRFK
- ProtClustDB:   CLSK955837
- HAMAP:   MF_01057
- InterPro:   IPR003358
- PANTHER:   PTHR23417:SF1

Pfam domain/function: PF02390 Methyltransf_4

EC number: =2.1.1.33

Molecular weight: Translated: 24960; Mature: 24829

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00327 BACTERIAL_OPSIN_RET

Important sites: BINDING 57-57 BINDING 82-82 BINDING 109-109 BINDING 167-167

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRGRYPARLYVTAPPPEIAARYYRSWPAKELYHTPEHFPPVSAEGLFGYNAPLTLEFGC
CCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECC
ATGEYLCALAAAQPSSCFVGIDIVAKPLYRAVERAVAGNLSNILFIHADARLIYQRIPTA
CCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCHH
ALHSIILHFPPPLLRNRQRNQLLVSPQLLECAARTLVPGGYLSFLTDHPALFALMQELLP
HHHHHHHHCCCHHHCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHH
AFPALRATPASVEELAVFESHYHRRWAARGRTISGLRIERVMED
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
GRGRYPARLYVTAPPPEIAARYYRSWPAKELYHTPEHFPPVSAEGLFGYNAPLTLEFGC
CCCCCCEEEEEECCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECC
ATGEYLCALAAAQPSSCFVGIDIVAKPLYRAVERAVAGNLSNILFIHADARLIYQRIPTA
CCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCHH
ALHSIILHFPPPLLRNRQRNQLLVSPQLLECAARTLVPGGYLSFLTDHPALFALMQELLP
HHHHHHHHCCCHHHCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHH
AFPALRATPASVEELAVFESHYHRRWAARGRTISGLRIERVMED
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA