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The map label for this gene is rocF [H]

Identifier: 222526412

GI number: 222526412

Start: 3939278

End: 3940186

Strand: Direct

Name: rocF [H]

Synonym: Chy400_3178

Alternate gene names: 222526412

Gene position: 3939278-3940186 (Clockwise)

Preceding gene: 222526411

Following gene: 222526414

Centisome position: 74.76

GC content: 58.31

Gene sequence:

>909_bases
ATGAGTAGTGGATCACAGATTGCAATTCTCGGCGTTCCCATCGATCTTGGAGCCGGACGGCGTGGCGTCGATATGGGGCC
GAGTGCCATTCGCTACGCCGGTCTGAGCCGAAGACTGGGCGAGTTGGGCTATCAGGTGGTTGATTTCGGCAATCTGACGG
TGCCGATGGTCGAGACGACCCCACCGCCACCACCTGATTCACGCCTGCGCTATCTTGAGCCGATTGCCGATATGTGTGGG
CGGCTGGCCCGGCAGGTGGCCGATATTGTCCAGCAGGGGATGCTGCCCCTCATTCTGGGTGGTGACCATAGTTTAACTAT
CGGTTCCGCCAGTGGGAGTGCGCGGCAGCGACGACTTGGTCTGATCTGGATTGATGCCCACGCCGATTTTAACGATGAAC
ACACGACACCGAGTGGCAATATTCACGGCATGCCGCTGGCTGTGTTAACCGGACGCGGGCATCCGACGCTCACCGGTTTT
GCCGGTCGCATACCGGCTTTCGATCCGGCGCACGTCGTATTGATTGCCGTGCGCGATCTCGATCCGCTGGAGCGGGAAGC
ATTGCGCGCTTCGCCGATCACCGTCTTTACCATGCACGAGATTGATCGCTGTGGGATGGCAACGGTGATGGAGCGGGCGC
TGGCAATTGCCACGACCGGTACTGAAGGATTTCATCTCAGTTTTGATCTCGATGTTGTCGATCCGCGCGAGGCGCCCGGT
GTGGGTACACCGGTAAGCAGTGGGATTTCGGCTCGCGAATCACATCTGGCGATGGAACTGATCGCCGAGAGTGGTGCGCT
GCGTAGTCTGGATGTGGTCGAAGTTAATCCGATCCTCGATGAGCGTAACGCGACTGCGCAGTTGGCCGTCGATCTGGTTT
TGTCAGCGTTAGGTAAACGTATTTTGTAG

Upstream 100 bases:

>100_bases
CACGGCGGGCCTATTTCCGCAATGGTGTGCTCGAAGTCTTCTTCGGCCCGCCAGAGACCCTCTCGCTGAAGACGGATGCC
CAGGAGGAGTCGACCCCTTC

Downstream 100 bases:

>100_bases
TGCTGGAGAACCGGCCTATACTGTCGCAATAGTGAATGTCGGGCGGGCTTCCAACCCGCCCGACATTGTCTGTCCAGGCA
CTAGATCGTCACCTGATACT

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSSGSQIAILGVPIDLGAGRRGVDMGPSAIRYAGLSRRLGELGYQVVDFGNLTVPMVETTPPPPPDSRLRYLEPIADMCG
RLARQVADIVQQGMLPLILGGDHSLTIGSASGSARQRRLGLIWIDAHADFNDEHTTPSGNIHGMPLAVLTGRGHPTLTGF
AGRIPAFDPAHVVLIAVRDLDPLEREALRASPITVFTMHEIDRCGMATVMERALAIATTGTEGFHLSFDLDVVDPREAPG
VGTPVSSGISARESHLAMELIAESGALRSLDVVEVNPILDERNATAQLAVDLVLSALGKRIL

Sequences:

>Translated_302_residues
MSSGSQIAILGVPIDLGAGRRGVDMGPSAIRYAGLSRRLGELGYQVVDFGNLTVPMVETTPPPPPDSRLRYLEPIADMCG
RLARQVADIVQQGMLPLILGGDHSLTIGSASGSARQRRLGLIWIDAHADFNDEHTTPSGNIHGMPLAVLTGRGHPTLTGF
AGRIPAFDPAHVVLIAVRDLDPLEREALRASPITVFTMHEIDRCGMATVMERALAIATTGTEGFHLSFDLDVVDPREAPG
VGTPVSSGISARESHLAMELIAESGALRSLDVVEVNPILDERNATAQLAVDLVLSALGKRIL
>Mature_301_residues
SSGSQIAILGVPIDLGAGRRGVDMGPSAIRYAGLSRRLGELGYQVVDFGNLTVPMVETTPPPPPDSRLRYLEPIADMCGR
LARQVADIVQQGMLPLILGGDHSLTIGSASGSARQRRLGLIWIDAHADFNDEHTTPSGNIHGMPLAVLTGRGHPTLTGFA
GRIPAFDPAHVVLIAVRDLDPLEREALRASPITVFTMHEIDRCGMATVMERALAIATTGTEGFHLSFDLDVVDPREAPGV
GTPVSSGISARESHLAMELIAESGALRSLDVVEVNPILDERNATAQLAVDLVLSALGKRIL

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=305, Percent_Identity=40.9836065573771, Blast_Score=203, Evalue=1e-52,
Organism=Homo sapiens, GI10947139, Length=308, Percent_Identity=39.2857142857143, Blast_Score=191, Evalue=5e-49,
Organism=Homo sapiens, GI37537722, Length=311, Percent_Identity=27.9742765273312, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1789306, Length=293, Percent_Identity=26.962457337884, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71996843, Length=229, Percent_Identity=35.3711790393013, Blast_Score=144, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6325146, Length=293, Percent_Identity=33.1058020477816, Blast_Score=148, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24638886, Length=308, Percent_Identity=33.4415584415584, Blast_Score=144, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32035; Mature: 31904

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGSQIAILGVPIDLGAGRRGVDMGPSAIRYAGLSRRLGELGYQVVDFGNLTVPMVETT
CCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECC
PPPPPDSRLRYLEPIADMCGRLARQVADIVQQGMLPLILGGDHSLTIGSASGSARQRRLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCHHEEEE
LIWIDAHADFNDEHTTPSGNIHGMPLAVLTGRGHPTLTGFAGRIPAFDPAHVVLIAVRDL
EEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCC
DPLEREALRASPITVFTMHEIDRCGMATVMERALAIATTGTEGFHLSFDLDVVDPREAPG
CHHHHHHHCCCCEEEEEECHHHHCCHHHHHHHHHEEEECCCCCEEEEEEEEEECCCCCCC
VGTPVSSGISARESHLAMELIAESGALRSLDVVEVNPILDERNATAQLAVDLVLSALGKR
CCCCHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHC
IL
CC
>Mature Secondary Structure 
SSGSQIAILGVPIDLGAGRRGVDMGPSAIRYAGLSRRLGELGYQVVDFGNLTVPMVETT
CCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECC
PPPPPDSRLRYLEPIADMCGRLARQVADIVQQGMLPLILGGDHSLTIGSASGSARQRRLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCHHEEEE
LIWIDAHADFNDEHTTPSGNIHGMPLAVLTGRGHPTLTGFAGRIPAFDPAHVVLIAVRDL
EEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCC
DPLEREALRASPITVFTMHEIDRCGMATVMERALAIATTGTEGFHLSFDLDVVDPREAPG
CHHHHHHHCCCCEEEEEECHHHHCCHHHHHHHHHEEEECCCCCEEEEEEEEEECCCCCCC
VGTPVSSGISARESHLAMELIAESGALRSLDVVEVNPILDERNATAQLAVDLVLSALGKR
CCCCHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHC
IL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]