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The map label for this gene is nuoC [H]

Identifier: 222526370

GI number: 222526370

Start: 3879274

End: 3879792

Strand: Direct

Name: nuoC [H]

Synonym: Chy400_3136

Alternate gene names: 222526370

Gene position: 3879274-3879792 (Clockwise)

Preceding gene: 222526369

Following gene: 222526371

Centisome position: 73.63

GC content: 54.91

Gene sequence:

>519_bases
ATGGATAATCAAACGGTGCTTGCTGCATTACGTGAACGGTTTGCGGCCGAGATTCTGGCTGTCAATGAGTTTCGCGGCGA
TCTGAGTCTGACCTTCACGCCCAAGGGCTATCTGGCTGCGGCTCAGTTTTTGCGCGATGACCCTGATCTTGCCTATACGT
TCCTGGAAAATCTTTGCGGGGTTGATTACCTCGGACGCAAGCCGCGCTTTGAAGTGGTCGCGCATCTGACCAGTATGCGC
CATCGTCATCGTGTGTGTTTGAAAGTCGGTTGTGATGAGCCTGAACCAACGGTGCCGTCGCTGACGCCACTCTTCCCGAC
GGCCAATTATCAGGAACGCGAGACGTTCGATCTGCTTGGCATCCGGTTTGACGGCCATCCGTCGCTGACCCGCATTTTGT
TGCCGGACGATTGGGTCGGCCATCCGCTCCGCAAGGATCATCCGCTTGGCGATGAAGAGATTGCGTTTACGTTCAATCAG
GAACGTATTTACGCTCGTAAGCCGTTCGTGAGGGAGTAG

Upstream 100 bases:

>100_bases
GGCATTATGATGCTGCATCAAAAGGTGATGCGCGAGAAGATCAGTGGCAAGAAGGAATCTCCCATCCGCATTGATCAGCC
GCTTGTGCAGGTGAAGTAGT

Downstream 100 bases:

>100_bases
CCGCGTATGACCGAACCGATCACTGTACCCACACCGCAGCAGATCATTGAGCCGGCTGTGGCTGGACGCACCGAGACGAT
GGTGCTGAATATGGGGCCGC

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MDNQTVLAALRERFAAEILAVNEFRGDLSLTFTPKGYLAAAQFLRDDPDLAYTFLENLCGVDYLGRKPRFEVVAHLTSMR
HRHRVCLKVGCDEPEPTVPSLTPLFPTANYQERETFDLLGIRFDGHPSLTRILLPDDWVGHPLRKDHPLGDEEIAFTFNQ
ERIYARKPFVRE

Sequences:

>Translated_172_residues
MDNQTVLAALRERFAAEILAVNEFRGDLSLTFTPKGYLAAAQFLRDDPDLAYTFLENLCGVDYLGRKPRFEVVAHLTSMR
HRHRVCLKVGCDEPEPTVPSLTPLFPTANYQERETFDLLGIRFDGHPSLTRILLPDDWVGHPLRKDHPLGDEEIAFTFNQ
ERIYARKPFVRE
>Mature_172_residues
MDNQTVLAALRERFAAEILAVNEFRGDLSLTFTPKGYLAAAQFLRDDPDLAYTFLENLCGVDYLGRKPRFEVVAHLTSMR
HRHRVCLKVGCDEPEPTVPSLTPLFPTANYQERETFDLLGIRFDGHPSLTRILLPDDWVGHPLRKDHPLGDEEIAFTFNQ
ERIYARKPFVRE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=141, Percent_Identity=36.8794326241135, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI145693162, Length=151, Percent_Identity=40.3973509933775, Blast_Score=104, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71990788, Length=151, Percent_Identity=37.7483443708609, Blast_Score=90, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32563621, Length=151, Percent_Identity=37.7483443708609, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24656494, Length=158, Percent_Identity=37.3417721518987, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 19786; Mature: 19786

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQTVLAALRERFAAEILAVNEFRGDLSLTFTPKGYLAAAQFLRDDPDLAYTFLENLCG
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHCC
VDYLGRKPRFEVVAHLTSMRHRHRVCLKVGCDEPEPTVPSLTPLFPTANYQERETFDLLG
CCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
IRFDGHPSLTRILLPDDWVGHPLRKDHPLGDEEIAFTFNQERIYARKPFVRE
EEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCC
>Mature Secondary Structure
MDNQTVLAALRERFAAEILAVNEFRGDLSLTFTPKGYLAAAQFLRDDPDLAYTFLENLCG
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHCC
VDYLGRKPRFEVVAHLTSMRHRHRVCLKVGCDEPEPTVPSLTPLFPTANYQERETFDLLG
CCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
IRFDGHPSLTRILLPDDWVGHPLRKDHPLGDEEIAFTFNQERIYARKPFVRE
EEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA