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The map label for this gene is bioH [H]

Identifier: 222526103

GI number: 222526103

Start: 3541058

End: 3541894

Strand: Direct

Name: bioH [H]

Synonym: Chy400_2860

Alternate gene names: 222526103

Gene position: 3541058-3541894 (Clockwise)

Preceding gene: 222526102

Following gene: 222526105

Centisome position: 67.21

GC content: 53.76

Gene sequence:

>837_bases
ATGAGCGTTATCCACCTCGATAACCGTCTGGCACACTACGAAGTCTTTGGTCGTGGCCAGCCGATCATCTTTCTGCATAG
CTGGATCGGTTCGTGGCGCTATTGGGTGCCAATTATGGACATTGCTTCAGAGCGCCATCGCGCCTACGCCTTTGACTTCT
GGGGGTTTGGCGAAAGCGACCGCCGTGGCGACCAGTTTACCGTGCCGACGTATGTCGAGATGTTGACTCAATTTATGGAT
CGTCTTGGTATTGCGCGCGCTACGCTGGTTGGTCACGGCATGGGGGGTATGGTCGCGATCCTCGCTGCTCATCAACACCC
TGAGCGATTCAACCGTCTGCTCACCGTCTGTACGCCATTACACGGTCAGGTATTGGCGCAACACATCAAGCCGGGCACAC
TCTCGCGACTGTTGGGGATGAATACCAGCCAGAATGGCTGGGCACGTATGGTGCGGACATTGCAGGTGGCAGATGCTGAA
ATTCAGCAGGAGATTGAAGAAGATACGTCGAGCCTGAGTGAGAAGGTATTGTCACAGGTTCACGAGTCGTTGTTAGAGAC
CGATCTCCGCCCATACATCATCTCCTTGCAGACACCACTGCTGGCGGTCTACGGTGGGAAAGACCCGATTGTCAATGCTG
CACATGCCGCATTTCTCAATGAACTGGCGGAGCGTCCGATCCAGTTGCTTGTGCTGCCTAAAGCCAGTCACTTTCCGTTT
CTCGAACAGGCAAATACGTTTGGTCGGTTGTTACTCGATTTTCTGGTCTCGCAGGGAACTGCGATTGAGATCAAAGAAGA
GTGGCGTCGCCGTGTCAATCAGCGAGAGTATTTGTGA

Upstream 100 bases:

>100_bases
AGATTTGGGTGACGAGTGAATTAGGAAAGGGAAGCACATTTGCTTTTGCCATACCGCTACAGCAAGAGACAAATGGCTCG
TACACCGAGGAGGTGGAACT

Downstream 100 bases:

>100_bases
TATTTGGGTAGTGAAGACGGGAAGCAGGAGAGGTGACTCTGATACCTTCACCTGCCGATACGCCATCAGGCTGCGGATGA
CGCTAACACTACGCTTCGAC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSVIHLDNRLAHYEVFGRGQPIIFLHSWIGSWRYWVPIMDIASERHRAYAFDFWGFGESDRRGDQFTVPTYVEMLTQFMD
RLGIARATLVGHGMGGMVAILAAHQHPERFNRLLTVCTPLHGQVLAQHIKPGTLSRLLGMNTSQNGWARMVRTLQVADAE
IQQEIEEDTSSLSEKVLSQVHESLLETDLRPYIISLQTPLLAVYGGKDPIVNAAHAAFLNELAERPIQLLVLPKASHFPF
LEQANTFGRLLLDFLVSQGTAIEIKEEWRRRVNQREYL

Sequences:

>Translated_278_residues
MSVIHLDNRLAHYEVFGRGQPIIFLHSWIGSWRYWVPIMDIASERHRAYAFDFWGFGESDRRGDQFTVPTYVEMLTQFMD
RLGIARATLVGHGMGGMVAILAAHQHPERFNRLLTVCTPLHGQVLAQHIKPGTLSRLLGMNTSQNGWARMVRTLQVADAE
IQQEIEEDTSSLSEKVLSQVHESLLETDLRPYIISLQTPLLAVYGGKDPIVNAAHAAFLNELAERPIQLLVLPKASHFPF
LEQANTFGRLLLDFLVSQGTAIEIKEEWRRRVNQREYL
>Mature_277_residues
SVIHLDNRLAHYEVFGRGQPIIFLHSWIGSWRYWVPIMDIASERHRAYAFDFWGFGESDRRGDQFTVPTYVEMLTQFMDR
LGIARATLVGHGMGGMVAILAAHQHPERFNRLLTVCTPLHGQVLAQHIKPGTLSRLLGMNTSQNGWARMVRTLQVADAEI
QQEIEEDTSSLSEKVLSQVHESLLETDLRPYIISLQTPLLAVYGGKDPIVNAAHAAFLNELAERPIQLLVLPKASHFPFL
EQANTFGRLLLDFLVSQGTAIEIKEEWRRRVNQREYL

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 31683; Mature: 31552

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIHLDNRLAHYEVFGRGQPIIFLHSWIGSWRYWVPIMDIASERHRAYAFDFWGFGESD
CCEEEECCCHHHEEEECCCCCEEEEEHHHCCHHHHHHHHHHHHCCHHEEEEEECCCCCCC
RRGDQFTVPTYVEMLTQFMDRLGIARATLVGHGMGGMVAILAAHQHPERFNRLLTVCTPL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCH
HGQVLAQHIKPGTLSRLLGMNTSQNGWARMVRTLQVADAEIQQEIEEDTSSLSEKVLSQV
HHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HESLLETDLRPYIISLQTPLLAVYGGKDPIVNAAHAAFLNELAERPIQLLVLPKASHFPF
HHHHHHCCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCH
LEQANTFGRLLLDFLVSQGTAIEIKEEWRRRVNQREYL
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVIHLDNRLAHYEVFGRGQPIIFLHSWIGSWRYWVPIMDIASERHRAYAFDFWGFGESD
CEEEECCCHHHEEEECCCCCEEEEEHHHCCHHHHHHHHHHHHCCHHEEEEEECCCCCCC
RRGDQFTVPTYVEMLTQFMDRLGIARATLVGHGMGGMVAILAAHQHPERFNRLLTVCTPL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCH
HGQVLAQHIKPGTLSRLLGMNTSQNGWARMVRTLQVADAEIQQEIEEDTSSLSEKVLSQV
HHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HESLLETDLRPYIISLQTPLLAVYGGKDPIVNAAHAAFLNELAERPIQLLVLPKASHFPF
HHHHHHCCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCH
LEQANTFGRLLLDFLVSQGTAIEIKEEWRRRVNQREYL
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA