| Definition | Chloroflexus sp. Y-400-fl chromosome, complete genome. |
|---|---|
| Accession | NC_012032 |
| Length | 5,268,950 |
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The map label for this gene is fabG [H]
Identifier: 222525843
GI number: 222525843
Start: 3229977
End: 3230726
Strand: Direct
Name: fabG [H]
Synonym: Chy400_2596
Alternate gene names: 222525843
Gene position: 3229977-3230726 (Clockwise)
Preceding gene: 222525842
Following gene: 222525850
Centisome position: 61.3
GC content: 57.07
Gene sequence:
>750_bases ATGATTGATTTCAACGGACAGGTAGCAATCGTCACCGGCGGTTCGGGCGGTATCGGACAGGCAGTGGTAGAGGGTCTGGC CCGTTATGGTGCCCGAGTGCTGGTAGGTTATCACCACAATGAAGCAGCCGCGACTGATGTGGTAGCGGCCGTCCAGTCCT CTGGTCGTGAAGCCGCAGCGCTGGCAATCGATGTGCGCGAGCCGGATAGTGGCAATGTGCTGGTAGCCACAGCAATAGAG CGCTGGGGAAAACTCGACATACTCATCAACTGTGCCGGTATTGCCGATTACGGCCCATTAAGCGAGATGAGCAGTGAACG GTGGCGGCAGACGATTCAGACGAATCTGACCGGCATCTACCACACCTGTCGAGCAGCATTGCGACCGATGATGCAGCAGC GTTATGGACGTATTGTTAATCTGGCGGCGCTCTACGGTACATCGGGCTTTCCCGGTCAGGCCGATTTTGCTGCGGCGGCT GGCGGGATCATCGGTTTGACACGAGCACTGGCCCGTGAAGCTGCTCCATGGCAGATAACAGTTAACGCTGTTGCGCCGGG TATGATCGAGACCGACTTGATAGAAGTGATTCCTGCAGAAATCCAGCAGTGGAGTGCCGGTATCATTGCGCTCCGCCGTT TGGGTAAGCCGGAGGAAGTTGCCGCAGCAGTGTTGTTTCTTGCCTCACCGGCCGCCTCGTATATTACCGGCCAAACGTTG ATGGTCGATGGTGGCTGGACGATGGCTTGA
Upstream 100 bases:
>100_bases CTGCGATCCGCTTTCTCGTTTCGCCTCGTGCTTCGTACATCACTGGCCATGTCTTGACAATTGACGGCGGTTGGGTGATG CCCTAACGACGGATGCGATC
Downstream 100 bases:
>100_bases TGCATACTACCACTGAGATACAGAAGACACAGAGGTTGATAGGTGAATCGTACTTGCAGGGATTGAGTGATTGTCGAGTA GCGGATGTCGCTAATGTGAG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 249; Mature: 249
Protein sequence:
>249_residues MIDFNGQVAIVTGGSGGIGQAVVEGLARYGARVLVGYHHNEAAATDVVAAVQSSGREAAALAIDVREPDSGNVLVATAIE RWGKLDILINCAGIADYGPLSEMSSERWRQTIQTNLTGIYHTCRAALRPMMQQRYGRIVNLAALYGTSGFPGQADFAAAA GGIIGLTRALAREAAPWQITVNAVAPGMIETDLIEVIPAEIQQWSAGIIALRRLGKPEEVAAAVLFLASPAASYITGQTL MVDGGWTMA
Sequences:
>Translated_249_residues MIDFNGQVAIVTGGSGGIGQAVVEGLARYGARVLVGYHHNEAAATDVVAAVQSSGREAAALAIDVREPDSGNVLVATAIE RWGKLDILINCAGIADYGPLSEMSSERWRQTIQTNLTGIYHTCRAALRPMMQQRYGRIVNLAALYGTSGFPGQADFAAAA GGIIGLTRALAREAAPWQITVNAVAPGMIETDLIEVIPAEIQQWSAGIIALRRLGKPEEVAAAVLFLASPAASYITGQTL MVDGGWTMA >Mature_249_residues MIDFNGQVAIVTGGSGGIGQAVVEGLARYGARVLVGYHHNEAAATDVVAAVQSSGREAAALAIDVREPDSGNVLVATAIE RWGKLDILINCAGIADYGPLSEMSSERWRQTIQTNLTGIYHTCRAALRPMMQQRYGRIVNLAALYGTSGFPGQADFAAAA GGIIGLTRALAREAAPWQITVNAVAPGMIETDLIEVIPAEIQQWSAGIIALRRLGKPEEVAAAVLFLASPAASYITGQTL MVDGGWTMA
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=39.7540983606557, Blast_Score=147, Evalue=6e-36, Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=36.7588932806324, Blast_Score=145, Evalue=2e-35, Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=32.6446280991736, Blast_Score=122, Evalue=2e-28, Organism=Homo sapiens, GI10190704, Length=242, Percent_Identity=32.6446280991736, Blast_Score=122, Evalue=3e-28, Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=33.6, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI5031737, Length=241, Percent_Identity=31.1203319502075, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI4504505, Length=253, Percent_Identity=32.0158102766798, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=31.7269076305221, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI59889578, Length=197, Percent_Identity=34.5177664974619, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=28.6821705426357, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI33667109, Length=250, Percent_Identity=29.2, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=29.7029702970297, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI83715985, Length=258, Percent_Identity=27.1317829457364, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4503817, Length=226, Percent_Identity=25.2212389380531, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI20149619, Length=230, Percent_Identity=26.0869565217391, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI4503301, Length=246, Percent_Identity=26.4227642276423, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=29.2397660818713, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=21.8274111675127, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI126723191, Length=203, Percent_Identity=26.6009852216749, Blast_Score=69, Evalue=4e-12, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=41.6, Blast_Score=182, Evalue=2e-47, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=33.6065573770492, Blast_Score=143, Evalue=1e-35, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=32.6848249027237, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=29.8387096774194, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=33.6032388663968, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=27.8884462151394, Blast_Score=120, Evalue=8e-29, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=33.7448559670782, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=35.3658536585366, Blast_Score=113, Evalue=9e-27, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=33.6032388663968, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=29.1828793774319, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=29.5019157088123, Blast_Score=95, Evalue=3e-21, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=31.7269076305221, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1787526, Length=242, Percent_Identity=25.2066115702479, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787820, Length=167, Percent_Identity=25.748502994012, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=36.3265306122449, Blast_Score=161, Evalue=3e-40, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=36.4705882352941, Blast_Score=149, Evalue=2e-36, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=31.5589353612167, Blast_Score=120, Evalue=8e-28, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=32.1285140562249, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=31.2757201646091, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=33.0645161290323, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17568967, Length=191, Percent_Identity=35.6020942408377, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=32.5301204819277, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=30.3501945525292, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=27.3408239700375, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=26.615969581749, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17563726, Length=281, Percent_Identity=27.7580071174377, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=29.4776119402985, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=27.6515151515151, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI193203115, Length=243, Percent_Identity=28.3950617283951, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI193203117, Length=245, Percent_Identity=27.7551020408163, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=27.9245283018868, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=28.6259541984733, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=30.4347826086957, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=26.9961977186312, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=30.3370786516854, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=28.9473684210526, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=28.3464566929134, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17538486, Length=275, Percent_Identity=27.6363636363636, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=27.0676691729323, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=26.615969581749, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=25.9067357512953, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=25.9398496240602, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=26.4822134387352, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=26.5060240963855, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=28.7313432835821, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17561272, Length=249, Percent_Identity=28.1124497991968, Blast_Score=71, Evalue=6e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=235, Percent_Identity=34.8936170212766, Blast_Score=126, Evalue=3e-30, Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=30.6772908366534, Blast_Score=114, Evalue=1e-26, Organism=Saccharomyces cerevisiae, GI6322067, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=9e-12, Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=36.3265306122449, Blast_Score=140, Evalue=9e-34, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=34.6613545816733, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=33.8582677165354, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=35.7142857142857, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=31.2, Blast_Score=114, Evalue=8e-26, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=32.6771653543307, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=31.8725099601594, Blast_Score=110, Evalue=9e-25, Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=27.5193798449612, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI18859837, Length=211, Percent_Identity=32.2274881516588, Blast_Score=93, Evalue=1e-19, Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24581726, Length=192, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=25.3807106598985, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=25.130890052356, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21355631, Length=172, Percent_Identity=29.0697674418605, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24641232, Length=243, Percent_Identity=27.1604938271605, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI116007236, Length=232, Percent_Identity=27.1551724137931, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24640492, Length=242, Percent_Identity=24.7933884297521, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26106; Mature: 26106
Theoretical pI: Translated: 5.01; Mature: 5.01
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIDFNGQVAIVTGGSGGIGQAVVEGLARYGARVLVGYHHNEAAATDVVAAVQSSGREAAA CCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCEEE LAIDVREPDSGNVLVATAIERWGKLDILINCAGIADYGPLSEMSSERWRQTIQTNLTGIY EEEEECCCCCCCEEEEEEHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH HTCRAALRPMMQQRYGRIVNLAALYGTSGFPGQADFAAAAGGIIGLTRALAREAAPWQIT HHHHHHHHHHHHHHHHHHEEHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEE VNAVAPGMIETDLIEVIPAEIQQWSAGIIALRRLGKPEEVAAAVLFLASPAASYITGQTL EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCEE MVDGGWTMA EEECCEECC >Mature Secondary Structure MIDFNGQVAIVTGGSGGIGQAVVEGLARYGARVLVGYHHNEAAATDVVAAVQSSGREAAA CCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCEEE LAIDVREPDSGNVLVATAIERWGKLDILINCAGIADYGPLSEMSSERWRQTIQTNLTGIY EEEEECCCCCCCEEEEEEHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH HTCRAALRPMMQQRYGRIVNLAALYGTSGFPGQADFAAAAGGIIGLTRALAREAAPWQIT HHHHHHHHHHHHHHHHHHEEHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEE VNAVAPGMIETDLIEVIPAEIQQWSAGIIALRRLGKPEEVAAAVLFLASPAASYITGQTL EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCEE MVDGGWTMA EEECCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]