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The map label for this gene is dhaL [H]

Identifier: 222524714

GI number: 222524714

Start: 1830001

End: 1830648

Strand: Direct

Name: dhaL [H]

Synonym: Chy400_1441

Alternate gene names: 222524714

Gene position: 1830001-1830648 (Clockwise)

Preceding gene: 222524707

Following gene: 222524715

Centisome position: 34.73

GC content: 59.41

Gene sequence:

>648_bases
ATGCCAATCACAGTAGAACACGTCACGCACTTCTTGACAGCGGCGGCGGAAATTATTCATGCTCATCGTGACGAGCTAAC
TGCACTGGATGCAGCAATTGGTGATGCCGATCATGGCGCAAACCTTGATCGTGGATTCGCTGCGGTGCTTTCCCGCCTGC
CCACCGTTGCCGACAAAGACATCGGCACCGTGCTCAAGACGACCGGAATGACGATTGTCTCGACAGTAGGCGGTGCTTCC
GGCCCCCTGTACGGTACTGCCTTCGTTCGCGCCGGTATGGCTCTGGCAGATCGGCATGAACTGAGTGACGAAGATGTTGT
CCTGGCCCTGGAGGCTGCCCTGGCCGGCATCGTGGCGCGTGGCAAAGCGCAACGCGGTGAAAAGACGATGGTTGATGCGC
TGGCCCCGGCTATCGAAGCGCTCCAATCAGCGCTGGCCGAGGGCAAGTCGTTAGGACGGGCATTGCTGGCTGCGGCTGCG
GCTGCTGAGGCAGGGGCAAAAGCAACCATCCCTATGCTGGCGATGAAGGGACGTGCCTCATACCTTGGTGAACGCAGTAT
CGGGCATCAGGATCCGGGAGCAACTTCGACGGCGTATCTGTTACGAGCGCTGGCGATGACGTGTAGCCGTAATGAGGAGG
AGGCATGA

Upstream 100 bases:

>100_bases
GTATCCGTGGTATGATGCGGGTACGACGTCATGATCTAGATGATCTAGCATGCGCGGTTTGCAGACCAGCGCGCATGATG
CAACTACGAGCGAGGCAACG

Downstream 100 bases:

>100_bases
TAGGGCTCTTGATCGTCTCGCATAGCGCACGATTGGCAGAAGGCGTGCAAGAGTTTGTCGGCCAAATCAGTGGGGGTCAG
ATTCCGATTATCGCTGCTGG

Product: dihydroxyacetone kinase subunit L

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPITVEHVTHFLTAAAEIIHAHRDELTALDAAIGDADHGANLDRGFAAVLSRLPTVADKDIGTVLKTTGMTIVSTVGGAS
GPLYGTAFVRAGMALADRHELSDEDVVLALEAALAGIVARGKAQRGEKTMVDALAPAIEALQSALAEGKSLGRALLAAAA
AAEAGAKATIPMLAMKGRASYLGERSIGHQDPGATSTAYLLRALAMTCSRNEEEA

Sequences:

>Translated_215_residues
MPITVEHVTHFLTAAAEIIHAHRDELTALDAAIGDADHGANLDRGFAAVLSRLPTVADKDIGTVLKTTGMTIVSTVGGAS
GPLYGTAFVRAGMALADRHELSDEDVVLALEAALAGIVARGKAQRGEKTMVDALAPAIEALQSALAEGKSLGRALLAAAA
AAEAGAKATIPMLAMKGRASYLGERSIGHQDPGATSTAYLLRALAMTCSRNEEEA
>Mature_214_residues
PITVEHVTHFLTAAAEIIHAHRDELTALDAAIGDADHGANLDRGFAAVLSRLPTVADKDIGTVLKTTGMTIVSTVGGASG
PLYGTAFVRAGMALADRHELSDEDVVLALEAALAGIVARGKAQRGEKTMVDALAPAIEALQSALAEGKSLGRALLAAAAA
AEAGAKATIPMLAMKGRASYLGERSIGHQDPGATSTAYLLRALAMTCSRNEEEA

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sens

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=173, Percent_Identity=34.1040462427746, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787449, Length=206, Percent_Identity=48.5436893203884, Blast_Score=202, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17565018, Length=193, Percent_Identity=32.1243523316062, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323570, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 22022; Mature: 21891

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITVEHVTHFLTAAAEIIHAHRDELTALDAAIGDADHGANLDRGFAAVLSRLPTVADKD
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHH
IGTVLKTTGMTIVSTVGGASGPLYGTAFVRAGMALADRHELSDEDVVLALEAALAGIVAR
HHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GKAQRGEKTMVDALAPAIEALQSALAEGKSLGRALLAAAAAAEAGAKATIPMLAMKGRAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHH
YLGERSIGHQDPGATSTAYLLRALAMTCSRNEEEA
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PITVEHVTHFLTAAAEIIHAHRDELTALDAAIGDADHGANLDRGFAAVLSRLPTVADKD
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHH
IGTVLKTTGMTIVSTVGGASGPLYGTAFVRAGMALADRHELSDEDVVLALEAALAGIVAR
HHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GKAQRGEKTMVDALAPAIEALQSALAEGKSLGRALLAAAAAAEAGAKATIPMLAMKGRAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHH
YLGERSIGHQDPGATSTAYLLRALAMTCSRNEEEA
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10493123 [H]