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The map label for this gene is ftsK [H]

Identifier: 222524621

GI number: 222524621

Start: 1718020

End: 1720371

Strand: Direct

Name: ftsK [H]

Synonym: Chy400_1345

Alternate gene names: 222524621

Gene position: 1718020-1720371 (Clockwise)

Preceding gene: 222524612

Following gene: 222524622

Centisome position: 32.61

GC content: 58.16

Gene sequence:

>2352_bases
ATGGCTTCACGCAGTGGTAATAAATCAACAGGATCACGACGAGCGAGCAGTCAGAAGCGCGGCAAAAGCAGCGCGAAAGG
GGGCTGGCGGATCGTCTTGCGACCCGAACACCAACGTGAACTTTTCGCGTTGGGGCTGATGCTGGTTGCTGTCCTGACCA
TTATCTTTGTCTTTACCGGCGAAGCTGGCGGTCTGGGAACTCTCTATCTCAATACCGTGCGTTCGCTGTTCGGTGCCGGT
GTCTTTTTTGTCCCGCTCACGCTCTTCATGATCGGGCTGGCGATTCTCTGGCAAGAGCGCATGCACGATGCCAGTCTGAG
CGGTGCCAATGTTCTGGGTACCGGCATGATATTACTGGCCATGCTGGGTCTGCTTGAAGTGCCGGTACATTCCATTCTCA
TCGCTGATCGAATGAATGAGGGTGGGGGCTGGATTGGTTACTGGCTGCTTGAACTGCTTCAGATGGCGATTGGGCAGATC
GCAGCGGTGCTGGTGATTCTGGCGCTCGGTCTGGCCGGCCTGCTGCTCACGTTCAATCTTACGGTACGCGAGCTGGTGGT
GGGGATGGTCGAACGTACTATCGCGTTCTGGCAGGTGTTGTGGAGTGCACCACGACGCCCGCAATCATCACCGGCAACGC
TGCCGCGCAGTGGCGCCGATCTGGTATTTTCCCCACCTCCCCAGGGTGGGAGTGATGATGATATTGTGCCGACCCCAATC
GCGGCCCGTCCTACCCGGGCCAGCCTCTTCCAACGCCCTACGCCTGAGCTACCTCCACCGGCCAGAGAGCCAGCGGTGTC
GGTAAAGCCGATTACACCGGTGAAGCCCGAACCGGTACAAGAGGTGGTGCAGGAACCGCTAGATGGCTTTGAGATTTCGC
CGGTACGCCGGGCATGGCCGCTGCCTTCCCTCGATCTGCTCCTGGAACGCACGGTCGATGGCGGGATTACTGATGAAGAA
CGCCGACTCAAGGCACGGGTGATCGAGGAGACCCTGGCCAGTTTTAAGGTCGAAGCCCGTGTTGTGGGGGTGAATACCGG
CCCGGCGGTAACCCAGTTTGAGCTGCAACCGGCAGTAGGGGTGAAAGTCGCCAAGATTACGACGCTCGAACGCGACCTGG
CACTGGCGCTGGCAGCCCAATCGATACGAATTGAAGCACCAATTCCAGGCAAGAATGTAGTTGGGATCGAGATTCCCAAC
AGCGCGATTGCCATGGTGTCACTGCGCGAGGTGCTCGACAGCGAGGAGTTTGAAACCTTCCGCGGGCGGCTGAAATTGCC
GCTGGGTAAAGATGTCAGCGGTACGCCGGTGATTGCTGATCTGACCAAAATGCCCCACCTGCTGGTGGCCGGTGCAACCG
GTTCGGGGAAGTCGGTGGCTATCAATGCGTTTCTCTGCGGTCTGCTCTTGAAGCATACGCCTGATGAACTCAAGCTCATT
CTGATCGACCCCAAGATGGTCGAGATGATTGTTTACAACCATATCCCCCATCTGCTCTCGCCGGTCGTCACCGAAGTGGA
ACGGGTGGTGCCAACGCTGAAGTGGGCAACCCGCGAGATGGAACGCCGGTATAAGGTCTTCGCCCGTAACGGTTGTCGTA
ACATTGACAGTTATCGTCAACTGGCGCGTAAACGGGCCGATCTGGAACCGATGCCCTATATCGTGATTGTGATCGATGAG
CTGGCCGACCTGATGATGATGGCAGCCGATGAAGTCGAGACGTATATCTGTCGGCTGGCCCAGATGGCCCGCGCAACCGG
GATTCACCTGATTATTGCGACGCAGCGCCCTTCGGTTGATGTGATTACCGGTTTGATCAAGGCCAACTTCCCGTCACGAA
TTGCCTTTGCCGTCACGTCGCAAGTTGATAGCCGGGTGATCCTCGACGTGCCGGGTGCTGAACATCTGCTTGGCCGGGGT
GACATGCTGTATATGGCCGCCGACTCGGCCAAACTGATCCGGATTCAAGGCACCTACGTCGCCGACCGTGAAGTCGAGCG
GATCGTTGAGTTCTGGCGTCATGCCGCGCCACCGACCGAGGCGACTGCGGCCCAGCCGAATACGGCCACCGGTGAAGGAA
AGGCGGCTGAAGAGTCTTCCGGCGCTGAGCCATTCCGACCGCCAGCCGAGTTTCTTTCTCCCGCCGAACAAGATGAGTTA
TTACCGCAGGCAATTGCGCTTGTGGGTCAACACCAGCGTGCCTCTGCTTCGCTGTTGCAACGTCGGTTGCGCATCGGTTA
TTCAAAAGCCCAGCAATTGATCGATCTGCTCGAACAGCAGGGGTATGTCGGCCCAGCCGAGGGGGGACGTTCACGAGAAG
TGCTCAAGCGCAACGGTTCAGCAACGTCGTAA

Upstream 100 bases:

>100_bases
TAACATAATTGAATCTCCTAGACAGTAGCTTTCTCGCACAAATATGCTATAATCGTATCGCATATATTTTCATATATTTG
ATGCACTACAAGCAAAAGCC

Downstream 100 bases:

>100_bases
CAGCACAACACCAAAGGAACAATGCTATGGCAATCGAGGATTTCTACACGAAGACCCGGCGGATTCTGGCAAACCTGCTG
GAAGAGACGCCCAAAGCCGA

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: DNA translocase SpoIIIE; Stage III sporulation protein E [H]

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MASRSGNKSTGSRRASSQKRGKSSAKGGWRIVLRPEHQRELFALGLMLVAVLTIIFVFTGEAGGLGTLYLNTVRSLFGAG
VFFVPLTLFMIGLAILWQERMHDASLSGANVLGTGMILLAMLGLLEVPVHSILIADRMNEGGGWIGYWLLELLQMAIGQI
AAVLVILALGLAGLLLTFNLTVRELVVGMVERTIAFWQVLWSAPRRPQSSPATLPRSGADLVFSPPPQGGSDDDIVPTPI
AARPTRASLFQRPTPELPPPAREPAVSVKPITPVKPEPVQEVVQEPLDGFEISPVRRAWPLPSLDLLLERTVDGGITDEE
RRLKARVIEETLASFKVEARVVGVNTGPAVTQFELQPAVGVKVAKITTLERDLALALAAQSIRIEAPIPGKNVVGIEIPN
SAIAMVSLREVLDSEEFETFRGRLKLPLGKDVSGTPVIADLTKMPHLLVAGATGSGKSVAINAFLCGLLLKHTPDELKLI
LIDPKMVEMIVYNHIPHLLSPVVTEVERVVPTLKWATREMERRYKVFARNGCRNIDSYRQLARKRADLEPMPYIVIVIDE
LADLMMMAADEVETYICRLAQMARATGIHLIIATQRPSVDVITGLIKANFPSRIAFAVTSQVDSRVILDVPGAEHLLGRG
DMLYMAADSAKLIRIQGTYVADREVERIVEFWRHAAPPTEATAAQPNTATGEGKAAEESSGAEPFRPPAEFLSPAEQDEL
LPQAIALVGQHQRASASLLQRRLRIGYSKAQQLIDLLEQQGYVGPAEGGRSREVLKRNGSATS

Sequences:

>Translated_783_residues
MASRSGNKSTGSRRASSQKRGKSSAKGGWRIVLRPEHQRELFALGLMLVAVLTIIFVFTGEAGGLGTLYLNTVRSLFGAG
VFFVPLTLFMIGLAILWQERMHDASLSGANVLGTGMILLAMLGLLEVPVHSILIADRMNEGGGWIGYWLLELLQMAIGQI
AAVLVILALGLAGLLLTFNLTVRELVVGMVERTIAFWQVLWSAPRRPQSSPATLPRSGADLVFSPPPQGGSDDDIVPTPI
AARPTRASLFQRPTPELPPPAREPAVSVKPITPVKPEPVQEVVQEPLDGFEISPVRRAWPLPSLDLLLERTVDGGITDEE
RRLKARVIEETLASFKVEARVVGVNTGPAVTQFELQPAVGVKVAKITTLERDLALALAAQSIRIEAPIPGKNVVGIEIPN
SAIAMVSLREVLDSEEFETFRGRLKLPLGKDVSGTPVIADLTKMPHLLVAGATGSGKSVAINAFLCGLLLKHTPDELKLI
LIDPKMVEMIVYNHIPHLLSPVVTEVERVVPTLKWATREMERRYKVFARNGCRNIDSYRQLARKRADLEPMPYIVIVIDE
LADLMMMAADEVETYICRLAQMARATGIHLIIATQRPSVDVITGLIKANFPSRIAFAVTSQVDSRVILDVPGAEHLLGRG
DMLYMAADSAKLIRIQGTYVADREVERIVEFWRHAAPPTEATAAQPNTATGEGKAAEESSGAEPFRPPAEFLSPAEQDEL
LPQAIALVGQHQRASASLLQRRLRIGYSKAQQLIDLLEQQGYVGPAEGGRSREVLKRNGSATS
>Mature_782_residues
ASRSGNKSTGSRRASSQKRGKSSAKGGWRIVLRPEHQRELFALGLMLVAVLTIIFVFTGEAGGLGTLYLNTVRSLFGAGV
FFVPLTLFMIGLAILWQERMHDASLSGANVLGTGMILLAMLGLLEVPVHSILIADRMNEGGGWIGYWLLELLQMAIGQIA
AVLVILALGLAGLLLTFNLTVRELVVGMVERTIAFWQVLWSAPRRPQSSPATLPRSGADLVFSPPPQGGSDDDIVPTPIA
ARPTRASLFQRPTPELPPPAREPAVSVKPITPVKPEPVQEVVQEPLDGFEISPVRRAWPLPSLDLLLERTVDGGITDEER
RLKARVIEETLASFKVEARVVGVNTGPAVTQFELQPAVGVKVAKITTLERDLALALAAQSIRIEAPIPGKNVVGIEIPNS
AIAMVSLREVLDSEEFETFRGRLKLPLGKDVSGTPVIADLTKMPHLLVAGATGSGKSVAINAFLCGLLLKHTPDELKLIL
IDPKMVEMIVYNHIPHLLSPVVTEVERVVPTLKWATREMERRYKVFARNGCRNIDSYRQLARKRADLEPMPYIVIVIDEL
ADLMMMAADEVETYICRLAQMARATGIHLIIATQRPSVDVITGLIKANFPSRIAFAVTSQVDSRVILDVPGAEHLLGRGD
MLYMAADSAKLIRIQGTYVADREVERIVEFWRHAAPPTEATAAQPNTATGEGKAAEESSGAEPFRPPAEFLSPAEQDELL
PQAIALVGQHQRASASLLQRRLRIGYSKAQQLIDLLEQQGYVGPAEGGRSREVLKRNGSATS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=499, Percent_Identity=45.0901803607214, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 85160; Mature: 85029

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRSGNKSTGSRRASSQKRGKSSAKGGWRIVLRPEHQRELFALGLMLVAVLTIIFVFTG
CCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
EAGGLGTLYLNTVRSLFGAGVFFVPLTLFMIGLAILWQERMHDASLSGANVLGTGMILLA
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MLGLLEVPVHSILIADRMNEGGGWIGYWLLELLQMAIGQIAAVLVILALGLAGLLLTFNL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVRELVVGMVERTIAFWQVLWSAPRRPQSSPATLPRSGADLVFSPPPQGGSDDDIVPTPI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
AARPTRASLFQRPTPELPPPAREPAVSVKPITPVKPEPVQEVVQEPLDGFEISPVRRAWP
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHCC
LPSLDLLLERTVDGGITDEERRLKARVIEETLASFKVEARVVGVNTGPAVTQFELQPAVG
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEEECCCCC
VKVAKITTLERDLALALAAQSIRIEAPIPGKNVVGIEIPNSAIAMVSLREVLDSEEFETF
EEEEHEEHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHH
RGRLKLPLGKDVSGTPVIADLTKMPHLLVAGATGSGKSVAINAFLCGLLLKHTPDELKLI
HCEEECCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCEEHHHHHHHHHHHCCCCCEEEE
LIDPKMVEMIVYNHIPHLLSPVVTEVERVVPTLKWATREMERRYKVFARNGCRNIDSYRQ
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LARKRADLEPMPYIVIVIDELADLMMMAADEVETYICRLAQMARATGIHLIIATQRPSVD
HHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHH
VITGLIKANFPSRIAFAVTSQVDSRVILDVPGAEHLLGRGDMLYMAADSAKLIRIQGTYV
HHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCHHHHHCCCCEEEEEECCCEEEEEECCEE
ADREVERIVEFWRHAAPPTEATAAQPNTATGEGKAAEESSGAEPFRPPAEFLSPAEQDEL
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHH
LPQAIALVGQHQRASASLLQRRLRIGYSKAQQLIDLLEQQGYVGPAEGGRSREVLKRNGS
HHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCC
ATS
CCC
>Mature Secondary Structure 
ASRSGNKSTGSRRASSQKRGKSSAKGGWRIVLRPEHQRELFALGLMLVAVLTIIFVFTG
CCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
EAGGLGTLYLNTVRSLFGAGVFFVPLTLFMIGLAILWQERMHDASLSGANVLGTGMILLA
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MLGLLEVPVHSILIADRMNEGGGWIGYWLLELLQMAIGQIAAVLVILALGLAGLLLTFNL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVRELVVGMVERTIAFWQVLWSAPRRPQSSPATLPRSGADLVFSPPPQGGSDDDIVPTPI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
AARPTRASLFQRPTPELPPPAREPAVSVKPITPVKPEPVQEVVQEPLDGFEISPVRRAWP
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHCC
LPSLDLLLERTVDGGITDEERRLKARVIEETLASFKVEARVVGVNTGPAVTQFELQPAVG
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEEECCCCC
VKVAKITTLERDLALALAAQSIRIEAPIPGKNVVGIEIPNSAIAMVSLREVLDSEEFETF
EEEEHEEHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHH
RGRLKLPLGKDVSGTPVIADLTKMPHLLVAGATGSGKSVAINAFLCGLLLKHTPDELKLI
HCEEECCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCEEHHHHHHHHHHHCCCCCEEEE
LIDPKMVEMIVYNHIPHLLSPVVTEVERVVPTLKWATREMERRYKVFARNGCRNIDSYRQ
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LARKRADLEPMPYIVIVIDELADLMMMAADEVETYICRLAQMARATGIHLIIATQRPSVD
HHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHH
VITGLIKANFPSRIAFAVTSQVDSRVILDVPGAEHLLGRGDMLYMAADSAKLIRIQGTYV
HHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCHHHHHCCCCEEEEEECCCEEEEEECCEE
ADREVERIVEFWRHAAPPTEATAAQPNTATGEGKAAEESSGAEPFRPPAEFLSPAEQDEL
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHH
LPQAIALVGQHQRASASLLQRRLRIGYSKAQQLIDLLEQQGYVGPAEGGRSREVLKRNGS
HHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCC
ATS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3129532; 2507870; 9384377; 8160014; 10588743; 11062134; 11778051 [H]