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The map label for this gene is htpG [H]

Identifier: 222524568

GI number: 222524568

Start: 1654789

End: 1656687

Strand: Direct

Name: htpG [H]

Synonym: Chy400_1292

Alternate gene names: 222524568

Gene position: 1654789-1656687 (Clockwise)

Preceding gene: 222524567

Following gene: 222524570

Centisome position: 31.41

GC content: 57.29

Gene sequence:

>1899_bases
ATGACCACGGAACCGTTGACTGAAACTGGTCGGCAGTCGCATACGTTCAAAGCCGAAGTACAACAAGTACTCTACATTCT
CGCCCATTCACTCTACACCGACCGCGAGATTTTCCTGCGTGAACTGATCTCGAACGCTTCTGACGCGATCAATCGCGTGC
AGTTCGAGATGCTGACGAATCGCGAAGTGCGCGATCCTGACCTCGAACCACAAATCACCATCGAAGTCAACAAGGAAGCG
CGCACCCTCTCGATCAGCGATACCGGCATCGGCATGACAGCCGATGAAATGGTGGAGCATCTCGGTACGATTGCGCAATC
GGCAGCACGCGCCTTTGTCAAACAGGCCGGTGAGGGCGCCAAACAGACTGCCAGCGAGATTATTGGTCAGTTTGGCGTCG
GCTTTTACTCGGTATTTATGGTTGCCGACAAGGTAACGGTTGTTTCCCAATCGTACCGCCCCGATGCACCGGCAGCGATG
TGGGAGTCGAGCGGTGGCGATAGCTTCACGGTTGGCCCCGCGACCCGCGAGCGTCGTGGTACCACCATTACGTTGCACCT
GAAAGAAGACGCGACTGAATTCGCCGATCCATGGCGGATCGAGCAGATCGTGCGTCGTCATTCCAATTATGTCGCCTTCC
CGATTATGCTCGATGGTCGCCAGATCAATGCGCGCACGGCGATCTGGCGCAAAGCCCCGCGTGATGTCACGAACGACGAA
TACAACGGCTATTACCGCCAGCTCACCCTCGACAGCCAGCCACCACTCAGCTTCATCCACATTTCGACTGACGCGCCGGT
TGATCTGCACGCCATTCTCTACATTCCATCGCGGCGCGAGCGCGGCATCCTCGAACGCCGCATCGAAGGTCAGATCAAAC
TCTATTCGCGCAAAGTTCTGATCCTTGAAGAAGCCAAAGATTTGCTGCCCGCCTATTTCCGCTTCGTTGAAGGTGTGGTG
GATAGCGAAGACCTACCGCTGAACGTCTCGCGGGAAAGCGTTCAGAGTGGTACCGCCGGTGGATCGCCGGTCATGCAACG
CCTGCGCAAAACGCTCACCGGTCGTCTCCACAAGGAGTTGAATGAACTGGCCGAGCGCGATCCGGAGAAGTATCGCACCT
TCTGGAAGGAATTCGGCCCGTTCATCAAAGAGGGTATTGCTACCGATTACGAGCATCGCAATGATCTACTCAAGCTGCTG
CGGGTGCAGACAACGAAGAGCGGTGAGGAATGGATCACGCTGGCGACCTACAAAGAGCGCATGATCCCCGGCCAGAAGGA
GATTTACTACCTGATGGCGGCCAGTCGCGATGCCGCGTTGAGCAGTCCGCACCTCGACCCACTGCGAGCACGCGACATCG
AAGTCATTCTCTTCACCGATCTGATGGATGGCTTTATGCTGTCAGGTCTGCGCGAATACGATGGGTTGCGCCTGCGCAAT
ATCGATGAGGGTGATCTTGATCTGCCGGGTGAGGTCGAACGACCGGCACCGGCCATTAATGACGAACAGTTCACCGCATT
GGCTGAACGCATTGCCGCAATTCTTGGCGACCGCCTGAAAGAAGTGCGCACATCGCGCGTGCTGCGTGACAGCCCGGCCC
GGCTGGTGGCCGATGAAGCAGCCTTTGGCCGCGAGATGCAGCGGATTCAGCAGGTACTCGGTCAGGAAGTGCAGATGGGG
CCGCGCATTTTGGAACTCAATCCGGCCCACCCGCTGATTGCAGCGCTGGCACAACGTGCTGCCTCCAATCCGAACGATCC
ACTCCTCAAACTGGCCGCCGAACAACTCTACGATAACGCACTGCTGATCGAAGGGTTACATCGCGATCCGGCGGCAATGG
CTCCGCGGATTTTGCAGTTGCTCGAACTGGCTGCCGGTGTGAACACGCCCCAGGCTTAA

Upstream 100 bases:

>100_bases
GCTGAGTGATTACAATGCATGATGGTGCTAATATCGCAATCCGCCGCTGCGTCAGGCGGATTGATGATGGTGCATTGTTC
AACTGTGACGAGGGAGAAGT

Downstream 100 bases:

>100_bases
TCGTTACCGTCGGTGAGCCTGCTGAACATGAGCTTCAGCAGGCTCACATTTTTATTCAGGGGGTACGGACTGCTTGCTAT
TCAAGATACCCCTTCAACAG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MTTEPLTETGRQSHTFKAEVQQVLYILAHSLYTDREIFLRELISNASDAINRVQFEMLTNREVRDPDLEPQITIEVNKEA
RTLSISDTGIGMTADEMVEHLGTIAQSAARAFVKQAGEGAKQTASEIIGQFGVGFYSVFMVADKVTVVSQSYRPDAPAAM
WESSGGDSFTVGPATRERRGTTITLHLKEDATEFADPWRIEQIVRRHSNYVAFPIMLDGRQINARTAIWRKAPRDVTNDE
YNGYYRQLTLDSQPPLSFIHISTDAPVDLHAILYIPSRRERGILERRIEGQIKLYSRKVLILEEAKDLLPAYFRFVEGVV
DSEDLPLNVSRESVQSGTAGGSPVMQRLRKTLTGRLHKELNELAERDPEKYRTFWKEFGPFIKEGIATDYEHRNDLLKLL
RVQTTKSGEEWITLATYKERMIPGQKEIYYLMAASRDAALSSPHLDPLRARDIEVILFTDLMDGFMLSGLREYDGLRLRN
IDEGDLDLPGEVERPAPAINDEQFTALAERIAAILGDRLKEVRTSRVLRDSPARLVADEAAFGREMQRIQQVLGQEVQMG
PRILELNPAHPLIAALAQRAASNPNDPLLKLAAEQLYDNALLIEGLHRDPAAMAPRILQLLELAAGVNTPQA

Sequences:

>Translated_632_residues
MTTEPLTETGRQSHTFKAEVQQVLYILAHSLYTDREIFLRELISNASDAINRVQFEMLTNREVRDPDLEPQITIEVNKEA
RTLSISDTGIGMTADEMVEHLGTIAQSAARAFVKQAGEGAKQTASEIIGQFGVGFYSVFMVADKVTVVSQSYRPDAPAAM
WESSGGDSFTVGPATRERRGTTITLHLKEDATEFADPWRIEQIVRRHSNYVAFPIMLDGRQINARTAIWRKAPRDVTNDE
YNGYYRQLTLDSQPPLSFIHISTDAPVDLHAILYIPSRRERGILERRIEGQIKLYSRKVLILEEAKDLLPAYFRFVEGVV
DSEDLPLNVSRESVQSGTAGGSPVMQRLRKTLTGRLHKELNELAERDPEKYRTFWKEFGPFIKEGIATDYEHRNDLLKLL
RVQTTKSGEEWITLATYKERMIPGQKEIYYLMAASRDAALSSPHLDPLRARDIEVILFTDLMDGFMLSGLREYDGLRLRN
IDEGDLDLPGEVERPAPAINDEQFTALAERIAAILGDRLKEVRTSRVLRDSPARLVADEAAFGREMQRIQQVLGQEVQMG
PRILELNPAHPLIAALAQRAASNPNDPLLKLAAEQLYDNALLIEGLHRDPAAMAPRILQLLELAAGVNTPQA
>Mature_631_residues
TTEPLTETGRQSHTFKAEVQQVLYILAHSLYTDREIFLRELISNASDAINRVQFEMLTNREVRDPDLEPQITIEVNKEAR
TLSISDTGIGMTADEMVEHLGTIAQSAARAFVKQAGEGAKQTASEIIGQFGVGFYSVFMVADKVTVVSQSYRPDAPAAMW
ESSGGDSFTVGPATRERRGTTITLHLKEDATEFADPWRIEQIVRRHSNYVAFPIMLDGRQINARTAIWRKAPRDVTNDEY
NGYYRQLTLDSQPPLSFIHISTDAPVDLHAILYIPSRRERGILERRIEGQIKLYSRKVLILEEAKDLLPAYFRFVEGVVD
SEDLPLNVSRESVQSGTAGGSPVMQRLRKTLTGRLHKELNELAERDPEKYRTFWKEFGPFIKEGIATDYEHRNDLLKLLR
VQTTKSGEEWITLATYKERMIPGQKEIYYLMAASRDAALSSPHLDPLRARDIEVILFTDLMDGFMLSGLREYDGLRLRNI
DEGDLDLPGEVERPAPAINDEQFTALAERIAAILGDRLKEVRTSRVLRDSPARLVADEAAFGREMQRIQQVLGQEVQMGP
RILELNPAHPLIAALAQRAASNPNDPLLKLAAEQLYDNALLIEGLHRDPAAMAPRILQLLELAAGVNTPQA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=623, Percent_Identity=38.0417335473515, Blast_Score=411, Evalue=1e-115,
Organism=Homo sapiens, GI4507677, Length=690, Percent_Identity=33.0434782608696, Blast_Score=356, Evalue=3e-98,
Organism=Homo sapiens, GI154146191, Length=421, Percent_Identity=33.729216152019, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI153792590, Length=421, Percent_Identity=33.729216152019, Blast_Score=229, Evalue=7e-60,
Organism=Homo sapiens, GI20149594, Length=421, Percent_Identity=32.3040380047506, Blast_Score=221, Evalue=1e-57,
Organism=Escherichia coli, GI1786679, Length=632, Percent_Identity=39.3987341772152, Blast_Score=452, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17559162, Length=675, Percent_Identity=33.4814814814815, Blast_Score=377, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17542208, Length=677, Percent_Identity=32.3485967503693, Blast_Score=353, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI115535205, Length=646, Percent_Identity=33.4365325077399, Blast_Score=349, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI115535167, Length=430, Percent_Identity=36.9767441860465, Blast_Score=281, Evalue=8e-76,
Organism=Saccharomyces cerevisiae, GI6325016, Length=418, Percent_Identity=33.9712918660287, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6323840, Length=418, Percent_Identity=33.4928229665072, Blast_Score=234, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24586016, Length=647, Percent_Identity=35.2395672333849, Blast_Score=358, Evalue=7e-99,
Organism=Drosophila melanogaster, GI21357739, Length=688, Percent_Identity=31.9767441860465, Blast_Score=341, Evalue=8e-94,
Organism=Drosophila melanogaster, GI17647529, Length=417, Percent_Identity=32.8537170263789, Blast_Score=248, Evalue=9e-66,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71112; Mature: 70981

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEPLTETGRQSHTFKAEVQQVLYILAHSLYTDREIFLRELISNASDAINRVQFEMLTN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
REVRDPDLEPQITIEVNKEARTLSISDTGIGMTADEMVEHLGTIAQSAARAFVKQAGEGA
CCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
KQTASEIIGQFGVGFYSVFMVADKVTVVSQSYRPDAPAAMWESSGGDSFTVGPATRERRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEECCCCCCCCC
TTITLHLKEDATEFADPWRIEQIVRRHSNYVAFPIMLDGRQINARTAIWRKAPRDVTNDE
CEEEEEECCCCHHHCCCHHHHHHHHHCCCEEEEEEEECCCEECHHHHHHHCCCCCCCCCC
YNGYYRQLTLDSQPPLSFIHISTDAPVDLHAILYIPSRRERGILERRIEGQIKLYSRKVL
CCCEEEEEEECCCCCEEEEEECCCCCCCEEEEEEECCCHHCCHHHHHHCCCEEEEECEEE
ILEEAKDLLPAYFRFVEGVVDSEDLPLNVSRESVQSGTAGGSPVMQRLRKTLTGRLHKEL
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
NELAERDPEKYRTFWKEFGPFIKEGIATDYEHRNDLLKLLRVQTTKSGEEWITLATYKER
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHH
MIPGQKEIYYLMAASRDAALSSPHLDPLRARDIEVILFTDLMDGFMLSGLREYDGLRLRN
HCCCCHHEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCEECC
IDEGDLDLPGEVERPAPAINDEQFTALAERIAAILGDRLKEVRTSRVLRDSPARLVADEA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AFGREMQRIQQVLGQEVQMGPRILELNPAHPLIAALAQRAASNPNDPLLKLAAEQLYDNA
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCH
LLIEGLHRDPAAMAPRILQLLELAAGVNTPQA
HEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTEPLTETGRQSHTFKAEVQQVLYILAHSLYTDREIFLRELISNASDAINRVQFEMLTN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
REVRDPDLEPQITIEVNKEARTLSISDTGIGMTADEMVEHLGTIAQSAARAFVKQAGEGA
CCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
KQTASEIIGQFGVGFYSVFMVADKVTVVSQSYRPDAPAAMWESSGGDSFTVGPATRERRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEECCCCCCCCC
TTITLHLKEDATEFADPWRIEQIVRRHSNYVAFPIMLDGRQINARTAIWRKAPRDVTNDE
CEEEEEECCCCHHHCCCHHHHHHHHHCCCEEEEEEEECCCEECHHHHHHHCCCCCCCCCC
YNGYYRQLTLDSQPPLSFIHISTDAPVDLHAILYIPSRRERGILERRIEGQIKLYSRKVL
CCCEEEEEEECCCCCEEEEEECCCCCCCEEEEEEECCCHHCCHHHHHHCCCEEEEECEEE
ILEEAKDLLPAYFRFVEGVVDSEDLPLNVSRESVQSGTAGGSPVMQRLRKTLTGRLHKEL
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
NELAERDPEKYRTFWKEFGPFIKEGIATDYEHRNDLLKLLRVQTTKSGEEWITLATYKER
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHH
MIPGQKEIYYLMAASRDAALSSPHLDPLRARDIEVILFTDLMDGFMLSGLREYDGLRLRN
HCCCCHHEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCEECC
IDEGDLDLPGEVERPAPAINDEQFTALAERIAAILGDRLKEVRTSRVLRDSPARLVADEA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AFGREMQRIQQVLGQEVQMGPRILELNPAHPLIAALAQRAASNPNDPLLKLAAEQLYDNA
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCH
LLIEGLHRDPAAMAPRILQLLELAAGVNTPQA
HEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA