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The map label for this gene is pilH [H]

Identifier: 222524205

GI number: 222524205

Start: 1170773

End: 1171156

Strand: Reverse

Name: pilH [H]

Synonym: Chy400_0926

Alternate gene names: 222524205

Gene position: 1171156-1170773 (Counterclockwise)

Preceding gene: 222524206

Following gene: 222524204

Centisome position: 22.23

GC content: 53.91

Gene sequence:

>384_bases
ATGGCTGATTCCGATATCCTGCTCATCGAGGATAGCCCCAGTCAGGCGCTCAACTTTCGCTTGATGCTGGAGCGGGCCGG
TTATCAGGTGCAGGTGGCGCCTGACGGCCTGACCGGATGGCGTACTGCCCGCACCCAGTTACCACGCATGATCCTGCTCG
ATATTGACTTGCCTGCGCTTGATGGATTTCAGGTATTGAGCCGCTTGAAGCGCGATCAGCAGACCAGAAACATTCCGGTC
GTGATGCTGACCCATCGTGATCGGATAGATAGTGTGCAACGCGCACTCGATTTGGGTGCTAACGATTATCTCTTCAAAGA
TGATGTGCCCTATGAACTGCTCAATGTCGTATCACAAATTCTGGCCCTATCCGGGCAGGAATAG

Upstream 100 bases:

>100_bases
AATGGACGAGGCTATGGTGATCCACCTTGATCCGGTAGCACTCTTGCATGATCCACGCCTGACCACCGGCGATCATTAGA
CATCATTGAAGGAGAAGTCC

Downstream 100 bases:

>100_bases
ACCAGCGAAAGGAAGCGGATATGTCATTCCTCAATCAGATTAGCCTCCGCAACAAAATATTGCTGCTCGTGGCATTGCTC
TTTGTTGGCATCATTATTGT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MADSDILLIEDSPSQALNFRLMLERAGYQVQVAPDGLTGWRTARTQLPRMILLDIDLPALDGFQVLSRLKRDQQTRNIPV
VMLTHRDRIDSVQRALDLGANDYLFKDDVPYELLNVVSQILALSGQE

Sequences:

>Translated_127_residues
MADSDILLIEDSPSQALNFRLMLERAGYQVQVAPDGLTGWRTARTQLPRMILLDIDLPALDGFQVLSRLKRDQQTRNIPV
VMLTHRDRIDSVQRALDLGANDYLFKDDVPYELLNVVSQILALSGQE
>Mature_126_residues
ADSDILLIEDSPSQALNFRLMLERAGYQVQVAPDGLTGWRTARTQLPRMILLDIDLPALDGFQVLSRLKRDQQTRNIPVV
MLTHRDRIDSVQRALDLGANDYLFKDDVPYELLNVVSQILALSGQE

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=39.3162393162393, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=36.2068965517241, Blast_Score=67, Evalue=3e-13,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=32.7586206896552, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 14378; Mature: 14247

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADSDILLIEDSPSQALNFRLMLERAGYQVQVAPDGLTGWRTARTQLPRMILLDIDLPAL
CCCCCEEEEECCCCHHHHHEEEEECCCCEEEECCCCCCCCHHHHHHCCEEEEEECCCCCC
DGFQVLSRLKRDQQTRNIPVVMLTHRDRIDSVQRALDLGANDYLFKDDVPYELLNVVSQI
CHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHH
LALSGQE
HHHCCCC
>Mature Secondary Structure 
ADSDILLIEDSPSQALNFRLMLERAGYQVQVAPDGLTGWRTARTQLPRMILLDIDLPAL
CCCCEEEEECCCCHHHHHEEEEECCCCEEEECCCCCCCCHHHHHHCCEEEEEECCCCCC
DGFQVLSRLKRDQQTRNIPVVMLTHRDRIDSVQRALDLGANDYLFKDDVPYELLNVVSQI
CHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHH
LALSGQE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]