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The map label for this gene is purQ [H]

Identifier: 222524091

GI number: 222524091

Start: 1018475

End: 1019239

Strand: Reverse

Name: purQ [H]

Synonym: Chy400_0807

Alternate gene names: 222524091

Gene position: 1019239-1018475 (Counterclockwise)

Preceding gene: 222524092

Following gene: 222524090

Centisome position: 19.34

GC content: 58.3

Gene sequence:

>765_bases
GTGGAACTGAAAGCACTCATTCTCCGCGCTCCCGGTATTAATCGGGATGCAGATGCGGCGCTGGCCTGTGAGCTGGCCGG
TGCCCAGCCCGAACGAATTCACGTCAATCGGTTGATCGAGCGCTCAATTCGATTGACTGACTATGCAATGCTGATTATTC
CGGGTGGTTTCTCGTATGGCGATCACCTGGGTGCCGGTCGCTTGCTGGCAGTTGATTTGATCCATCGCCTTGGCGAAGAA
CTTGAACGCTTTGTTGCCGATGGCCGGCCCGTCATTGGCATCTGTAACGGCTTTCAAGTGTTGGTGAAAGCAGGCTTACT
ACCTGGCCCGCTGCGGCAGTCACCGCGGGTAACCCTGACGACAAACGAATCGCAGCAGTTTGAATGTCGCTGGGTGCAGC
TCGAAGCAGTAGCGCATAGCCGGTGCCGGTTTACGCAGGGTATCGAGCAGCCCATTGAAGTGCCGGTTGCCCATGGTGAA
GGACGAATTGCTGTTCGGGATGAGGCAACCCTGGCCGAATTAGAAGCGAATGGGCTGGTAGCACTTCGCTATGTCGGCGA
GGGGTATCCGGCGAATCCCAACGGGTCACCACACGCGATTGCCGGTCTGTGCAATGCGCAGGGGAATGTACTGGGGTTGA
TGCCGCACCCCGAAAATGCTGTGTTGCCCCACCAGCATCCACGCTGGACACGCGAACCGGCCCGACGCGAGGGTGATGGG
TTGCAGATTTTTCGCAATGCCGTGCGCTACGCCGCGTCGCTGTAG

Upstream 100 bases:

>100_bases
ATGGGACGGAGATTAACGGTAAGCAAATTTTGCCCAACGTGCCGCAGCGTCTGCAAGCTGGTGATCGGATCAAGATCGGT
GAGGTAGAGATGGAGTTTCG

Downstream 100 bases:

>100_bases
CGTGCATGCAGAACGTGTCTTGCGGTTGGAAAGCCACCCTTAGCGGTGGGTACTGCTCTTTTTCATCAAACATGATGTGC
AGCCGGGCGTATGTCATATC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MELKALILRAPGINRDADAALACELAGAQPERIHVNRLIERSIRLTDYAMLIIPGGFSYGDHLGAGRLLAVDLIHRLGEE
LERFVADGRPVIGICNGFQVLVKAGLLPGPLRQSPRVTLTTNESQQFECRWVQLEAVAHSRCRFTQGIEQPIEVPVAHGE
GRIAVRDEATLAELEANGLVALRYVGEGYPANPNGSPHAIAGLCNAQGNVLGLMPHPENAVLPHQHPRWTREPARREGDG
LQIFRNAVRYAASL

Sequences:

>Translated_254_residues
MELKALILRAPGINRDADAALACELAGAQPERIHVNRLIERSIRLTDYAMLIIPGGFSYGDHLGAGRLLAVDLIHRLGEE
LERFVADGRPVIGICNGFQVLVKAGLLPGPLRQSPRVTLTTNESQQFECRWVQLEAVAHSRCRFTQGIEQPIEVPVAHGE
GRIAVRDEATLAELEANGLVALRYVGEGYPANPNGSPHAIAGLCNAQGNVLGLMPHPENAVLPHQHPRWTREPARREGDG
LQIFRNAVRYAASL
>Mature_254_residues
MELKALILRAPGINRDADAALACELAGAQPERIHVNRLIERSIRLTDYAMLIIPGGFSYGDHLGAGRLLAVDLIHRLGEE
LERFVADGRPVIGICNGFQVLVKAGLLPGPLRQSPRVTLTTNESQQFECRWVQLEAVAHSRCRFTQGIEQPIEVPVAHGE
GRIAVRDEATLAELEANGLVALRYVGEGYPANPNGSPHAIAGLCNAQGNVLGLMPHPENAVLPHQHPRWTREPARREGDG
LQIFRNAVRYAASL

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=277, Percent_Identity=34.2960288808664, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI48994899, Length=257, Percent_Identity=38.9105058365759, Blast_Score=139, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17553022, Length=274, Percent_Identity=27.007299270073, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321498, Length=269, Percent_Identity=32.3420074349442, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24582111, Length=265, Percent_Identity=34.3396226415094, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24582109, Length=265, Percent_Identity=34.3396226415094, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI17137292, Length=265, Percent_Identity=34.3396226415094, Blast_Score=144, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 27710; Mature: 27710

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKALILRAPGINRDADAALACELAGAQPERIHVNRLIERSIRLTDYAMLIIPGGFSYG
CCCCEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCC
DHLGAGRLLAVDLIHRLGEELERFVADGRPVIGICNGFQVLVKAGLLPGPLRQSPRVTLT
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCCCCCCEEEEE
TNESQQFECRWVQLEAVAHSRCRFTQGIEQPIEVPVAHGEGRIAVRDEATLAELEANGLV
ECCCCCEEEEEEEEEEHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCEEEEECCCCEE
ALRYVGEGYPANPNGSPHAIAGLCNAQGNVLGLMPHPENAVLPHQHPRWTREPARREGDG
EEEEECCCCCCCCCCCCHHEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHCCCCH
LQIFRNAVRYAASL
HHHHHHHHHHHHCC
>Mature Secondary Structure
MELKALILRAPGINRDADAALACELAGAQPERIHVNRLIERSIRLTDYAMLIIPGGFSYG
CCCCEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCC
DHLGAGRLLAVDLIHRLGEELERFVADGRPVIGICNGFQVLVKAGLLPGPLRQSPRVTLT
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCCCCCCEEEEE
TNESQQFECRWVQLEAVAHSRCRFTQGIEQPIEVPVAHGEGRIAVRDEATLAELEANGLV
ECCCCCEEEEEEEEEEHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCEEEEECCCCEE
ALRYVGEGYPANPNGSPHAIAGLCNAQGNVLGLMPHPENAVLPHQHPRWTREPARREGDG
EEEEECCCCCCCCCCCCHHEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHCCCCH
LQIFRNAVRYAASL
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA