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The map label for this gene is nucH [H]

Identifier: 222523885

GI number: 222523885

Start: 708898

End: 709443

Strand: Direct

Name: nucH [H]

Synonym: Chy400_0594

Alternate gene names: 222523885

Gene position: 708898-709443 (Clockwise)

Preceding gene: 222523884

Following gene: 222523904

Centisome position: 13.45

GC content: 60.07

Gene sequence:

>546_bases
GTGGTACAGCGTATCTTCACCATCTTCTTTATACAGATCATCTTCTTCATCAGTGGATGCAGCCGACCGGTGGCGACAGA
GCAAACCAGCCTCAGCGACTACCCACCACTTCCCGACAACCTGACGCGCGCCCAGGTTGTCCGCGTCGTCGATGGCGACA
CCATCATCGTGCGGATCGGGCGGGATGAAGAGCGGGTACGGCTAATTGGCATCAACACCCCAGAGTCGGCCGATCCGCGG
CGACCGGTCGAGTGTTTCGGGAAAGAAGCGGCGAGCAATGCGCGCAAACTCGTAGACAGACAAACCGTCCTGCTAGAAGA
CGACCCCTCACAAGACTCACGAGATCGGTTTGGCCGCCTCCTGCGCTACGTCTGGCTCGAAGACGGACGCATGGTCAATC
TGGAACAGATTCGACAAGGGTACGCCTACGAATACACCTACGACGTGCCATACCGCTATCAAGCGATCTTCCGGGCCGCC
GAAGCGGAAGCCCGCAACGCCCAGCGCGGGCTATGGGCACCGGAGACGTGCAACGGCCAGCGGTGA

Upstream 100 bases:

>100_bases
GTTCATCCTGATAATCAGCCTCCATAGGCTGCCCACAGCACAGGTAGCAACTTGAGTTACGATACCACCGAAACAGATTA
TAGCATTGGAGGAATCGACT

Downstream 100 bases:

>100_bases
AGGGCATTGCGAAGCCACTGCGCTGGAGGGGCGAGATACGACACGTATACCCTGTGCGGTGACAGATTACATGAACACCA
AGACGGGGCAGGCACAAAAC

Product: nuclease

Products: NA

Alternate protein names: TNase; Micrococcal nuclease; Staphylococcal nuclease [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MVQRIFTIFFIQIIFFISGCSRPVATEQTSLSDYPPLPDNLTRAQVVRVVDGDTIIVRIGRDEERVRLIGINTPESADPR
RPVECFGKEAASNARKLVDRQTVLLEDDPSQDSRDRFGRLLRYVWLEDGRMVNLEQIRQGYAYEYTYDVPYRYQAIFRAA
EAEARNAQRGLWAPETCNGQR

Sequences:

>Translated_181_residues
MVQRIFTIFFIQIIFFISGCSRPVATEQTSLSDYPPLPDNLTRAQVVRVVDGDTIIVRIGRDEERVRLIGINTPESADPR
RPVECFGKEAASNARKLVDRQTVLLEDDPSQDSRDRFGRLLRYVWLEDGRMVNLEQIRQGYAYEYTYDVPYRYQAIFRAA
EAEARNAQRGLWAPETCNGQR
>Mature_181_residues
MVQRIFTIFFIQIIFFISGCSRPVATEQTSLSDYPPLPDNLTRAQVVRVVDGDTIIVRIGRDEERVRLIGINTPESADPR
RPVECFGKEAASNARKLVDRQTVLLEDDPSQDSRDRFGRLLRYVWLEDGRMVNLEQIRQGYAYEYTYDVPYRYQAIFRAA
EAEARNAQRGLWAPETCNGQR

Specific function: Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5'-position of the phosphodiester bond [H]

COG id: COG1525

COG function: function code L; Micrococcal nuclease (thermonuclease) homologs

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thermonuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016071
- InterPro:   IPR006021
- InterPro:   IPR002071 [H]

Pfam domain/function: PF00565 SNase [H]

EC number: =3.1.31.1 [H]

Molecular weight: Translated: 20923; Mature: 20923

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50830 TNASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQRIFTIFFIQIIFFISGCSRPVATEQTSLSDYPPLPDNLTRAQVVRVVDGDTIIVRIG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEECCCEEEEEEC
RDEERVRLIGINTPESADPRRPVECFGKEAASNARKLVDRQTVLLEDDPSQDSRDRFGRL
CCCCEEEEEECCCCCCCCCCCCHHHHCHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHH
LRYVWLEDGRMVNLEQIRQGYAYEYTYDVPYRYQAIFRAAEAEARNAQRGLWAPETCNGQ
HHHHHHCCCCEECHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
R
C
>Mature Secondary Structure
MVQRIFTIFFIQIIFFISGCSRPVATEQTSLSDYPPLPDNLTRAQVVRVVDGDTIIVRIG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEECCCEEEEEEC
RDEERVRLIGINTPESADPRRPVECFGKEAASNARKLVDRQTVLLEDDPSQDSRDRFGRL
CCCCEEEEEECCCCCCCCCCCCHHHHCHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHH
LRYVWLEDGRMVNLEQIRQGYAYEYTYDVPYRYQAIFRAAEAEARNAQRGLWAPETCNGQ
HHHHHHCCCCEECHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045422 [H]