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The map label for this gene is ysnA [H]

Identifier: 222523818

GI number: 222523818

Start: 627161

End: 627763

Strand: Reverse

Name: ysnA [H]

Synonym: Chy400_0526

Alternate gene names: 222523818

Gene position: 627763-627161 (Counterclockwise)

Preceding gene: 222523819

Following gene: 222523817

Centisome position: 11.91

GC content: 57.38

Gene sequence:

>603_bases
ATGCGTGAATTACTGATTGCGACCCACAATCCCGGCAAATTACGTGAGTTTGCCGCTATCTTTGCCGATCTCAATCTGCG
CCTCTATTCATTAGCCGATGTGGGCATTCAGGAGACTATCGAAGAGACCGGCCAGACATTTGCGGAAAACGCACGCCTCA
AGGCCGAAGGTTATCTGGCGTTGAGTGGTTTGCCGACACTGGCCGATGATAGTGGTCTGGAAGTAGCCGCTCTCGGCGGT
GCTCCCGGTGTCTATTCGGCGCGTTATGGTGGCCTGTCAGGGCCGGCTCAGTTGCAGTACCTGCTCGACCAGATGCGTGA
TATTCCCTGGCATCAACGGTTGGCCCGTTTCGTTTGTGTGATTGCCCTGGCCCATCCCGACCATCCAACCGAGCTGGTGG
AAGGTACGCTTCCCGGTGTGATTGAATTTGCGCCGCGTGGGAGTGGTGGCTTCGGCTATGACCCACTCTTTTACGTGCTC
GACGAGGACGCAACTCTGGCCGAGTTGAGTGCTGAACGGAAGAATCAGATCAGTCATCGGGCGCAGGCGGCACGCGCAGC
GCGTGAGGTATTGGCGCGCTGGCAGCGTTCGTCTGGTAGTTAG

Upstream 100 bases:

>100_bases
TCAATTGGCTGCTACAGCAAACGTGTTGTTATCACAGTACGCGATACCTCCAGGTGTCACGTAACACGCGCAAACATCGG
CTTATCGCAAAGTGACTCGT

Downstream 100 bases:

>100_bases
TGATGGCCCAGATCGGTGCACGGAGACTATTGTGCTGGTGGCGTCATTCGCTTCGGGAAGTACAGGTAATGCGTTACTGG
TGCGAGCAGGTGATCAGGCC

Product: RdgB/HAM1 family non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MRELLIATHNPGKLREFAAIFADLNLRLYSLADVGIQETIEETGQTFAENARLKAEGYLALSGLPTLADDSGLEVAALGG
APGVYSARYGGLSGPAQLQYLLDQMRDIPWHQRLARFVCVIALAHPDHPTELVEGTLPGVIEFAPRGSGGFGYDPLFYVL
DEDATLAELSAERKNQISHRAQAARAAREVLARWQRSSGS

Sequences:

>Translated_200_residues
MRELLIATHNPGKLREFAAIFADLNLRLYSLADVGIQETIEETGQTFAENARLKAEGYLALSGLPTLADDSGLEVAALGG
APGVYSARYGGLSGPAQLQYLLDQMRDIPWHQRLARFVCVIALAHPDHPTELVEGTLPGVIEFAPRGSGGFGYDPLFYVL
DEDATLAELSAERKNQISHRAQAARAAREVLARWQRSSGS
>Mature_200_residues
MRELLIATHNPGKLREFAAIFADLNLRLYSLADVGIQETIEETGQTFAENARLKAEGYLALSGLPTLADDSGLEVAALGG
APGVYSARYGGLSGPAQLQYLLDQMRDIPWHQRLARFVCVIALAHPDHPTELVEGTLPGVIEFAPRGSGGFGYDPLFYVL
DEDATLAELSAERKNQISHRAQAARAAREVLARWQRSSGS

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=189, Percent_Identity=50.7936507936508, Blast_Score=176, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17556833, Length=190, Percent_Identity=32.1052631578947, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21704; Mature: 21704

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELLIATHNPGKLREFAAIFADLNLRLYSLADVGIQETIEETGQTFAENARLKAEGYLA
CCCEEEEECCCHHHHHHHHHHHHCCEEEEEHHHCCHHHHHHHHHHHHHHCCCCCCCCEEE
LSGLPTLADDSGLEVAALGGAPGVYSARYGGLSGPAQLQYLLDQMRDIPWHQRLARFVCV
ECCCCCCCCCCCCEEEEECCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
IALAHPDHPTELVEGTLPGVIEFAPRGSGGFGYDPLFYVLDEDATLAELSAERKNQISHR
HHHCCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
AQAARAAREVLARWQRSSGS
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRELLIATHNPGKLREFAAIFADLNLRLYSLADVGIQETIEETGQTFAENARLKAEGYLA
CCCEEEEECCCHHHHHHHHHHHHCCEEEEEHHHCCHHHHHHHHHHHHHHCCCCCCCCEEE
LSGLPTLADDSGLEVAALGGAPGVYSARYGGLSGPAQLQYLLDQMRDIPWHQRLARFVCV
ECCCCCCCCCCCCEEEEECCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
IALAHPDHPTELVEGTLPGVIEFAPRGSGGFGYDPLFYVLDEDATLAELSAERKNQISHR
HHHCCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
AQAARAAREVLARWQRSSGS
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377; 1624460 [H]