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The map label for this gene is ilvE [H]

Identifier: 222523816

GI number: 222523816

Start: 625354

End: 626274

Strand: Reverse

Name: ilvE [H]

Synonym: Chy400_0524

Alternate gene names: 222523816

Gene position: 626274-625354 (Counterclockwise)

Preceding gene: 222523817

Following gene: 222523815

Centisome position: 11.89

GC content: 56.79

Gene sequence:

>921_bases
ATGCCGATCCAGAAAATGGATTACATCTGGTTCAATGGCGAGCTGGTGGAGTGGGATAAGGCGACGGTGCATGTGCTGTC
GCACGCCATTCATTACGGCACCAGCTTTTTCGAGGGCATTCGCTGTTACGAGACGCCACAGGGGCCGGCGATTTTTCGGC
TCACGCCGCATATGCAGCGCCTCATCGACTCGGCGAAGATTTATCGCACCACAATTCCCTACACCCTCGATCAGTTGGTG
GCAGCGGTCAAAGAAACCGTGCGCGCGAACCGCTTGCGCTCTGGCTACATTCGACCGGTGGTATTCCGTGGTTATGGCGA
GATCGGGGTCAATCCGCTCAACAATCCGGTTGAAGTAGCCATTGCAACCATCGAATGGGGCAAGTATCTCGGTGCTGAGG
CAATGGAACAGGGTGTCGATGTCTGTATCTCGTCGTGGAATCGGTTTGCCCCCAACACCATGCCGGCCCTCGCCAAAGCG
GGCGGCAACTACATGAATTCCCAGTTGATCAAGATGGAAGCAATAGCCAATGGCTACGCCGAGGGGATTGCCCTCGATGC
CGATGGTCATATCAGCGAGGGCAGTGGCGAAAACCTGTTCCTGGTGCGTAATGGCGTTGTCTACACGCCACCGTTGACCT
CATCGATCCTGAGCGGGATCACCCGTGATACGGTGATGACGTTGCTGCGTGAGATGGGGGTTGAAGTGCGTGAACAGGTG
CTCCCGCGGGAGATGCTCTACCTGGCCGATGAGCTGTTCTTTACCGGGACTGCTGCTGAGATAACGCCAATCCGATCAGT
GGATCGGATTCCTGTCGGTACAGGCCGGCGTGGCCCAATTACGGCTGCGGTGCAAGAGGTATTCTTCGGGATCGTGCAGG
GTGAGCGTCCTGATCGTTACGGGTGGCTCGAGTACGCATAA

Upstream 100 bases:

>100_bases
ACCGGTTCCTGGTGGTATCATCTGCTGGCAGCCCCAAGAACGCTGGCAGCAACCAGGTTTGTTTACAGGTGATTGGTGAT
ACGCAAGAAGGAGGCGATCA

Downstream 100 bases:

>100_bases
AGCGTCAGGAATAAGCCTGTCGCCAAGGTAAATAGTGTCGCGAAGCGGGGCGTAGCGCCACTACGCCCCTTTGTTTCGCA
ACCGCGATGTGTGATCTACT

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MPIQKMDYIWFNGELVEWDKATVHVLSHAIHYGTSFFEGIRCYETPQGPAIFRLTPHMQRLIDSAKIYRTTIPYTLDQLV
AAVKETVRANRLRSGYIRPVVFRGYGEIGVNPLNNPVEVAIATIEWGKYLGAEAMEQGVDVCISSWNRFAPNTMPALAKA
GGNYMNSQLIKMEAIANGYAEGIALDADGHISEGSGENLFLVRNGVVYTPPLTSSILSGITRDTVMTLLREMGVEVREQV
LPREMLYLADELFFTGTAAEITPIRSVDRIPVGTGRRGPITAAVQEVFFGIVQGERPDRYGWLEYA

Sequences:

>Translated_306_residues
MPIQKMDYIWFNGELVEWDKATVHVLSHAIHYGTSFFEGIRCYETPQGPAIFRLTPHMQRLIDSAKIYRTTIPYTLDQLV
AAVKETVRANRLRSGYIRPVVFRGYGEIGVNPLNNPVEVAIATIEWGKYLGAEAMEQGVDVCISSWNRFAPNTMPALAKA
GGNYMNSQLIKMEAIANGYAEGIALDADGHISEGSGENLFLVRNGVVYTPPLTSSILSGITRDTVMTLLREMGVEVREQV
LPREMLYLADELFFTGTAAEITPIRSVDRIPVGTGRRGPITAAVQEVFFGIVQGERPDRYGWLEYA
>Mature_305_residues
PIQKMDYIWFNGELVEWDKATVHVLSHAIHYGTSFFEGIRCYETPQGPAIFRLTPHMQRLIDSAKIYRTTIPYTLDQLVA
AVKETVRANRLRSGYIRPVVFRGYGEIGVNPLNNPVEVAIATIEWGKYLGAEAMEQGVDVCISSWNRFAPNTMPALAKAG
GNYMNSQLIKMEAIANGYAEGIALDADGHISEGSGENLFLVRNGVVYTPPLTSSILSGITRDTVMTLLREMGVEVREQVL
PREMLYLADELFFTGTAAEITPIRSVDRIPVGTGRRGPITAAVQEVFFGIVQGERPDRYGWLEYA

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=305, Percent_Identity=59.672131147541, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34039; Mature: 33908

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIQKMDYIWFNGELVEWDKATVHVLSHAIHYGTSFFEGIRCYETPQGPAIFRLTPHMQR
CCCCCCEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECHHHHH
LIDSAKIYRTTIPYTLDQLVAAVKETVRANRLRSGYIRPVVFRGYGEIGVNPLNNPVEVA
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEE
IATIEWGKYLGAEAMEQGVDVCISSWNRFAPNTMPALAKAGGNYMNSQLIKMEAIANGYA
EEEEHHHHHCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCHH
EGIALDADGHISEGSGENLFLVRNGVVYTPPLTSSILSGITRDTVMTLLREMGVEVREQV
CCEEECCCCCCCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LPREMLYLADELFFTGTAAEITPIRSVDRIPVGTGRRGPITAAVQEVFFGIVQGERPDRY
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
GWLEYA
CCCCCC
>Mature Secondary Structure 
PIQKMDYIWFNGELVEWDKATVHVLSHAIHYGTSFFEGIRCYETPQGPAIFRLTPHMQR
CCCCCEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECHHHHH
LIDSAKIYRTTIPYTLDQLVAAVKETVRANRLRSGYIRPVVFRGYGEIGVNPLNNPVEVA
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEE
IATIEWGKYLGAEAMEQGVDVCISSWNRFAPNTMPALAKAGGNYMNSQLIKMEAIANGYA
EEEEHHHHHCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCHH
EGIALDADGHISEGSGENLFLVRNGVVYTPPLTSSILSGITRDTVMTLLREMGVEVREQV
CCEEECCCCCCCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LPREMLYLADELFFTGTAAEITPIRSVDRIPVGTGRRGPITAAVQEVFFGIVQGERPDRY
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
GWLEYA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]