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The map label for this gene is corA [H]

Identifier: 222523781

GI number: 222523781

Start: 584657

End: 585592

Strand: Reverse

Name: corA [H]

Synonym: Chy400_0489

Alternate gene names: 222523781

Gene position: 585592-584657 (Counterclockwise)

Preceding gene: 222523782

Following gene: 222523780

Centisome position: 11.11

GC content: 51.6

Gene sequence:

>936_bases
ATGACGACGAATGCAATCGCTGCTACATCGGCGCACGATCATCTGCTTCAAGCCGGTTGGATGAGGTTATTCCGGCATCA
AGATGATCGACTGGCAGAGGTGAAGCGTGTGTACGGTATCGATCTGTTGGTAAGTTCCAGACGTGCGACAGTTGAGGAGT
ATGGTTTTTTGATCATCCCGGTGAACCTGATAGTTCACCGGGAACATGAATACCGCGAGACGAATGTGGTGTTCGCCCTG
GGTAAGTCAGTGCTCATTAGTCTCGAGACGCATCCTGGCACGTTGGATGTGGCAAGCCGGATCTTGCTTGAAGAAGTTCA
GGCTGGCAATAGCCATGATCCGGCCTCTGTCCTGTTTCTTGTGCTGCAATCGCTCAACGACACAGCTCATGCGACTATTC
GAGAGATTTCCGAGCGTCTCGACGAAACTGGTGCATCCGTAGCCAGCGCAGGTGGTGGTTACCAGATGGCAGGGCGTCAG
GTTGGTGTCGCGGATATTGCTGATATGGTGGCCAAACTGGCTGAAGCTGAGGAACTGGTTGCAAAGACAGTCGAGAGCCA
GATGATGATCGCCCGAGCGGTTCGCTGGTTACGACGCATCGAGAGCAGCAGGCGGTTCGGTCAGGCGCTACCTACGCTGG
TATCGGATATACACAGCTTGCGACGCTATGCACAATTTCAGCATGGCAAGATTCGCAATCTTCAGCAATCGTTGATGACC
ATGCTCGATCTTAAGCAAAACAATGTTATCAAAGTTTTCACTATCGTGACAGCGGTCTTCACGCCACCAACCCTGGTTGC
TGCCTTTTATGGACAGAACTTTGCTGAAATGCCCGAGTTGTTCCTGCCATGGGGAGAATGGGCAGTTATCGTCCTTACGG
GTTTAAGCGCAATTCTACCGTTGTTTTACATCAAAAAGAAGGGGTGGATGCGATGA

Upstream 100 bases:

>100_bases
GTAGGGATTGAAGGTGTCGCAAATCTCCACAACCAGCAATCCCTTATAACCAGGTGTTATGCCACCAGGAGTGTTACGAG
TTTTAGAGAGGAGACCTGCG

Downstream 100 bases:

>100_bases
CAACAGTTAATGAACTACCCGCATGGGTTCGTCTACGGGCAAGCAATCAGCAGGAGCTTGAGGAGGTAGCTCGCACGCAC
GAATTGTCCCTGATACCAGA

Product: Mg2 transporter protein CorA family protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTTNAIAATSAHDHLLQAGWMRLFRHQDDRLAEVKRVYGIDLLVSSRRATVEEYGFLIIPVNLIVHREHEYRETNVVFAL
GKSVLISLETHPGTLDVASRILLEEVQAGNSHDPASVLFLVLQSLNDTAHATIREISERLDETGASVASAGGGYQMAGRQ
VGVADIADMVAKLAEAEELVAKTVESQMMIARAVRWLRRIESSRRFGQALPTLVSDIHSLRRYAQFQHGKIRNLQQSLMT
MLDLKQNNVIKVFTIVTAVFTPPTLVAAFYGQNFAEMPELFLPWGEWAVIVLTGLSAILPLFYIKKKGWMR

Sequences:

>Translated_311_residues
MTTNAIAATSAHDHLLQAGWMRLFRHQDDRLAEVKRVYGIDLLVSSRRATVEEYGFLIIPVNLIVHREHEYRETNVVFAL
GKSVLISLETHPGTLDVASRILLEEVQAGNSHDPASVLFLVLQSLNDTAHATIREISERLDETGASVASAGGGYQMAGRQ
VGVADIADMVAKLAEAEELVAKTVESQMMIARAVRWLRRIESSRRFGQALPTLVSDIHSLRRYAQFQHGKIRNLQQSLMT
MLDLKQNNVIKVFTIVTAVFTPPTLVAAFYGQNFAEMPELFLPWGEWAVIVLTGLSAILPLFYIKKKGWMR
>Mature_310_residues
TTNAIAATSAHDHLLQAGWMRLFRHQDDRLAEVKRVYGIDLLVSSRRATVEEYGFLIIPVNLIVHREHEYRETNVVFALG
KSVLISLETHPGTLDVASRILLEEVQAGNSHDPASVLFLVLQSLNDTAHATIREISERLDETGASVASAGGGYQMAGRQV
GVADIADMVAKLAEAEELVAKTVESQMMIARAVRWLRRIESSRRFGQALPTLVSDIHSLRRYAQFQHGKIRNLQQSLMTM
LDLKQNNVIKVFTIVTAVFTPPTLVAAFYGQNFAEMPELFLPWGEWAVIVLTGLSAILPLFYIKKKGWMR

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=158, Percent_Identity=35.4430379746835, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 34764; Mature: 34633

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNAIAATSAHDHLLQAGWMRLFRHQDDRLAEVKRVYGIDLLVSSRRATVEEYGFLIIP
CCCCCCEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCHHHHHHCCEEEEE
VNLIVHREHEYRETNVVFALGKSVLISLETHPGTLDVASRILLEEVQAGNSHDPASVLFL
EEHEEECCHHHHHHHHHEEECCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
VLQSLNDTAHATIREISERLDETGASVASAGGGYQMAGRQVGVADIADMVAKLAEAEELV
HHHHHCHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
AKTVESQMMIARAVRWLRRIESSRRFGQALPTLVSDIHSLRRYAQFQHGKIRNLQQSLMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MLDLKQNNVIKVFTIVTAVFTPPTLVAAFYGQNFAEMPELFLPWGEWAVIVLTGLSAILP
HHHCCCCCEEHHHHHHHHHHCCHHHHHHHHCCCHHHCHHHHCCCCHHHHHHHHHHHHHHH
LFYIKKKGWMR
HHHHHHCCCCC
>Mature Secondary Structure 
TTNAIAATSAHDHLLQAGWMRLFRHQDDRLAEVKRVYGIDLLVSSRRATVEEYGFLIIP
CCCCCEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCHHHHHHCCEEEEE
VNLIVHREHEYRETNVVFALGKSVLISLETHPGTLDVASRILLEEVQAGNSHDPASVLFL
EEHEEECCHHHHHHHHHEEECCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
VLQSLNDTAHATIREISERLDETGASVASAGGGYQMAGRQVGVADIADMVAKLAEAEELV
HHHHHCHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
AKTVESQMMIARAVRWLRRIESSRRFGQALPTLVSDIHSLRRYAQFQHGKIRNLQQSLMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MLDLKQNNVIKVFTIVTAVFTPPTLVAAFYGQNFAEMPELFLPWGEWAVIVLTGLSAILP
HHHCCCCCEEHHHHHHHHHHCCHHHHHHHHCCCHHHCHHHHCCCCHHHHHHHHHHHHHHH
LFYIKKKGWMR
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]