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The map label for this gene is ykcC [H]

Identifier: 222523657

GI number: 222523657

Start: 428361

End: 429380

Strand: Reverse

Name: ykcC [H]

Synonym: Chy400_0363

Alternate gene names: 222523657

Gene position: 429380-428361 (Counterclockwise)

Preceding gene: 222523658

Following gene: 222523656

Centisome position: 8.15

GC content: 53.73

Gene sequence:

>1020_bases
ATGGTAAAACAACAACCAACCTTTTCGGTCGTCGCACCGGTGTACAACGAAGAACAACTGATTGCTGAGTTTTGCCGCCG
GGTGATTGCCGCGCTTGAGCCACTCGGCGAGCCGTTTGAGCTGGTACTGGTGAATGATGGCTGTCGTGATCGTTCACCAG
AAATTATGCGGGAACTGCATCAGCGCGATCCGCGCATTAAGGTGATTAACTTTTCGCGTAACTTTGGTCATCAAATCGCC
ATTACTGCCGGTACCGATTATGCCACCGGGAAGGCAGTGATTGTGATCGACTCTGACCTGCAAGACCCGCCAGAGGTGAT
CCCTGAGCTGATTGCGCGTTGGCGGGAAGGATATCAGGTTGTCTACGGTGTACGTGAAGAGCGCGAAGGTGAGACGTGGT
TTAAGAAGACGACCGCAGCGATCTTTTACCGGCTCATCGTGCGTATCACCAACGTCAATATTCCGGTTGATACCGGCGAT
TTTCGTTTGATGGATCGCAAAGTCGTTGATGCACTCAAGCGGATGCGTGAACACCACCGTTTCATGCGAGGTCTATCGGC
GTGGATCGGTTTTCGGCAAACCGGTGTGCCCTACCGCCGTCATGCCCGTGCTGCCGGAACGACAAAGTACCCTCTGCGCA
AGATGCTGCGCTTCGCGCTTGATGGGATTACCAGTTTCTCGTATTTGCCGCTCCAGTTGGCAACCTATCTCGGTTTTATT
GTGGCTGCCATCAGTATGATCTTCTTGCTGGTGGTCTTTGTGATGCGGCTTGCCGATCCGTCTGCCCCGGAACCGGCGTT
CTACGGTCAGGCCAGCACGCTGGCCAGTGTCCTCTTTCTTGGTGCTGTGCAGTTGATTTCACTGGGCATTATTGGCGAGT
ATGTGGGCCGTATCTACGATGAGGTAAAGGGACGGCCCCTCTACATTGTGGCCGAAGCGCTGGGGGTGGAAGAAGAACCT
GCAACTTCTCCGGCTTCAGTGCGTACAACCCATATGGAACAGTCAACATCTGTTAAGTAG

Upstream 100 bases:

>100_bases
AGTATTGAACCGTGCTCCTTCTCAACATGAACCCGTCCAGATTTGTTATCATCAGCACAACGCAACGAAGAGCCATCACC
ATTGATGGCGTGGAGGCAGT

Downstream 100 bases:

>100_bases
TCAGGAGGAGTGGTATGTCGCAGCGCGCCCCAGTTAGAGGATCGATGACGTCACGGCTATCGCTGGTCGGTGGATTCATC
CTGTTGCTGATCATTGTCGG

Product: glycosyl transferase family 2 protein

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MVKQQPTFSVVAPVYNEEQLIAEFCRRVIAALEPLGEPFELVLVNDGCRDRSPEIMRELHQRDPRIKVINFSRNFGHQIA
ITAGTDYATGKAVIVIDSDLQDPPEVIPELIARWREGYQVVYGVREEREGETWFKKTTAAIFYRLIVRITNVNIPVDTGD
FRLMDRKVVDALKRMREHHRFMRGLSAWIGFRQTGVPYRRHARAAGTTKYPLRKMLRFALDGITSFSYLPLQLATYLGFI
VAAISMIFLLVVFVMRLADPSAPEPAFYGQASTLASVLFLGAVQLISLGIIGEYVGRIYDEVKGRPLYIVAEALGVEEEP
ATSPASVRTTHMEQSTSVK

Sequences:

>Translated_339_residues
MVKQQPTFSVVAPVYNEEQLIAEFCRRVIAALEPLGEPFELVLVNDGCRDRSPEIMRELHQRDPRIKVINFSRNFGHQIA
ITAGTDYATGKAVIVIDSDLQDPPEVIPELIARWREGYQVVYGVREEREGETWFKKTTAAIFYRLIVRITNVNIPVDTGD
FRLMDRKVVDALKRMREHHRFMRGLSAWIGFRQTGVPYRRHARAAGTTKYPLRKMLRFALDGITSFSYLPLQLATYLGFI
VAAISMIFLLVVFVMRLADPSAPEPAFYGQASTLASVLFLGAVQLISLGIIGEYVGRIYDEVKGRPLYIVAEALGVEEEP
ATSPASVRTTHMEQSTSVK
>Mature_339_residues
MVKQQPTFSVVAPVYNEEQLIAEFCRRVIAALEPLGEPFELVLVNDGCRDRSPEIMRELHQRDPRIKVINFSRNFGHQIA
ITAGTDYATGKAVIVIDSDLQDPPEVIPELIARWREGYQVVYGVREEREGETWFKKTTAAIFYRLIVRITNVNIPVDTGD
FRLMDRKVVDALKRMREHHRFMRGLSAWIGFRQTGVPYRRHARAAGTTKYPLRKMLRFALDGITSFSYLPLQLATYLGFI
VAAISMIFLLVVFVMRLADPSAPEPAFYGQASTLASVLFLGAVQLISLGIIGEYVGRIYDEVKGRPLYIVAEALGVEEEP
ATSPASVRTTHMEQSTSVK

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=176, Percent_Identity=26.1363636363636, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788692, Length=302, Percent_Identity=42.7152317880795, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1788588, Length=315, Percent_Identity=36.5079365079365, Blast_Score=191, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24585265, Length=231, Percent_Identity=25.5411255411255, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 38268; Mature: 38268

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKQQPTFSVVAPVYNEEQLIAEFCRRVIAALEPLGEPFELVLVNDGCRDRSPEIMRELH
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHH
QRDPRIKVINFSRNFGHQIAITAGTDYATGKAVIVIDSDLQDPPEVIPELIARWREGYQV
HCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEE
VYGVREEREGETWFKKTTAAIFYRLIVRITNVNIPVDTGDFRLMDRKVVDALKRMREHHR
EECHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FMRGLSAWIGFRQTGVPYRRHARAAGTTKYPLRKMLRFALDGITSFSYLPLQLATYLGFI
HHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VAAISMIFLLVVFVMRLADPSAPEPAFYGQASTLASVLFLGAVQLISLGIIGEYVGRIYD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVKGRPLYIVAEALGVEEEPATSPASVRTTHMEQSTSVK
HHCCCCEEEEEHHHCCCCCCCCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MVKQQPTFSVVAPVYNEEQLIAEFCRRVIAALEPLGEPFELVLVNDGCRDRSPEIMRELH
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHH
QRDPRIKVINFSRNFGHQIAITAGTDYATGKAVIVIDSDLQDPPEVIPELIARWREGYQV
HCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEE
VYGVREEREGETWFKKTTAAIFYRLIVRITNVNIPVDTGDFRLMDRKVVDALKRMREHHR
EECHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FMRGLSAWIGFRQTGVPYRRHARAAGTTKYPLRKMLRFALDGITSFSYLPLQLATYLGFI
HHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VAAISMIFLLVVFVMRLADPSAPEPAFYGQASTLASVLFLGAVQLISLGIIGEYVGRIYD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVKGRPLYIVAEALGVEEEPATSPASVRTTHMEQSTSVK
HHCCCCEEEEEHHHCCCCCCCCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]