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The map label for this gene is yfjP [H]

Identifier: 222523553

GI number: 222523553

Start: 311538

End: 312134

Strand: Direct

Name: yfjP [H]

Synonym: Chy400_0259

Alternate gene names: 222523553

Gene position: 311538-312134 (Clockwise)

Preceding gene: 222523550

Following gene: 222523554

Centisome position: 5.91

GC content: 57.96

Gene sequence:

>597_bases
ATGGAACACGCACTTCAGCATCTACGCAACGTTGATCCAACGCTAGGGCACTGGATCGAACAGATTGGCCCATATACATT
GCAACGGCAGCCGCACGGCTTTGCCACGCTGGCCTATGCCATCATTAGCCAGCAACTATCACTGGTAGCGGCCCGAACCA
TTCGCGACCGTCTCAACGAGCGATTGGGCAGCCTGGCACCGGAGACTATCATTGCGGCTGATGAGACAGTACTGCGCGCT
GCCGGCCTCTCGGCTCAGAAGAGCAGCTACCTGCGCGACCTGGCCGAGCGCGTGATGAGTGGTCAACTCGACCTGAACCT
GCTGCCAACGCTCGACGATGAAACAGCCATCACACACCTGATGACCGTAAAGGGCATTGGGCGATGGACGGCTGAAATCT
ATCTGATGTTTGCCCTCGAACGACTGGATGTCCTGCCGGCTGCCGATCTGGGCCTGCGTGATGCTGTTCGTCTCATCTAC
GATCAACCACGCCTGCCCAAACCCCAGGAACTGCGTACCTTTGGTGAACGCTGGCGTCCCTACCGCAGCATTGCCTGCTG
GTACCTCTGGCAGGCACGGCGGATTATGATCAGTTAA

Upstream 100 bases:

>100_bases
CTTACCGTGATCGACATGACCGGCAGTTCCAATCACAAACATTGCCAGAAACTCTTGCATATCGTTTACAATACTGCTAA
GAGCATTGTACGATGAAACG

Downstream 100 bases:

>100_bases
GTAATCTCACGTTGTATCGTGGTCACAAACGTGGTATGATGGTCAATAAGAGGTAGAGGAAACGGTTTCGTATGATGCGG
ATTGATGGACGGTCACCAGA

Product: DNA-3-methyladenine glycosylase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MEHALQHLRNVDPTLGHWIEQIGPYTLQRQPHGFATLAYAIISQQLSLVAARTIRDRLNERLGSLAPETIIAADETVLRA
AGLSAQKSSYLRDLAERVMSGQLDLNLLPTLDDETAITHLMTVKGIGRWTAEIYLMFALERLDVLPAADLGLRDAVRLIY
DQPRLPKPQELRTFGERWRPYRSIACWYLWQARRIMIS

Sequences:

>Translated_198_residues
MEHALQHLRNVDPTLGHWIEQIGPYTLQRQPHGFATLAYAIISQQLSLVAARTIRDRLNERLGSLAPETIIAADETVLRA
AGLSAQKSSYLRDLAERVMSGQLDLNLLPTLDDETAITHLMTVKGIGRWTAEIYLMFALERLDVLPAADLGLRDAVRLIY
DQPRLPKPQELRTFGERWRPYRSIACWYLWQARRIMIS
>Mature_198_residues
MEHALQHLRNVDPTLGHWIEQIGPYTLQRQPHGFATLAYAIISQQLSLVAARTIRDRLNERLGSLAPETIIAADETVLRA
AGLSAQKSSYLRDLAERVMSGQLDLNLLPTLDDETAITHLMTVKGIGRWTAEIYLMFALERLDVLPAADLGLRDAVRLIY
DQPRLPKPQELRTFGERWRPYRSIACWYLWQARRIMIS

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Escherichia coli, GI1788383, Length=164, Percent_Identity=29.2682926829268, Blast_Score=64, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320990, Length=234, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 22629; Mature: 22629

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHALQHLRNVDPTLGHWIEQIGPYTLQRQPHGFATLAYAIISQQLSLVAARTIRDRLNE
CCHHHHHHHCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLGSLAPETIIAADETVLRAAGLSAQKSSYLRDLAERVMSGQLDLNLLPTLDDETAITHL
HHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHH
MTVKGIGRWTAEIYLMFALERLDVLPAADLGLRDAVRLIYDQPRLPKPQELRTFGERWRP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCH
YRSIACWYLWQARRIMIS
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEHALQHLRNVDPTLGHWIEQIGPYTLQRQPHGFATLAYAIISQQLSLVAARTIRDRLNE
CCHHHHHHHCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLGSLAPETIIAADETVLRAAGLSAQKSSYLRDLAERVMSGQLDLNLLPTLDDETAITHL
HHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHH
MTVKGIGRWTAEIYLMFALERLDVLPAADLGLRDAVRLIYDQPRLPKPQELRTFGERWRP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCH
YRSIACWYLWQARRIMIS
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]