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The map label for this gene is yqhT [H]

Identifier: 222523549

GI number: 222523549

Start: 303651

End: 304730

Strand: Direct

Name: yqhT [H]

Synonym: Chy400_0255

Alternate gene names: 222523549

Gene position: 303651-304730 (Clockwise)

Preceding gene: 222523546

Following gene: 222523550

Centisome position: 5.76

GC content: 59.91

Gene sequence:

>1080_bases
ATGACGAACCGATTGCAACAATTACGGGCAACGCTGGCCGCACGCGAATTACCGGCAATGTTGCTCACTGCGCCAACCAG
TCGCCGTTACATCAGCGGCTTCACCGGTAGCGCCGGTGCTTTGCTTATCAGTGCCGAAGCCGCCTTCTTGCTCACCGACG
GTCGCTATCTGATACGAGCTGCGGCTGAAGCACCGCACTTTACCCTGCGTGAGGTACGTCCTCCGGCCAGACCAATGACC
GCCCTGATCGCTGATCTGGCGAGCGAACTGGGCATCAAACGATTGGGCTTTGAAGCGGCGGTTATGACCGTTGCCGAGCA
TCGTCAGTACACCGCCGCGCTTGGCAATGCTATCGAGCTGGTTCCCACCGAGAATATTGTGGAAGAACTACGGATGGTCA
AGGATGAGGAAGAAATTGCGCTGCTGCGCCGGGCCGCCGCCATCACCGATGCTGCCCTGGCCGCAGTGCTACCCGCACTC
ACCCCTACCATGACCGAGCGTGAAGCGGCATGGCGCCTCGAAGTAGCACTGCACGACCTGGGTGCCGAAGGGCCGTCTTT
CCCGATTATCGTGGCTGCGGGTCGCAATAGTGCCCGTCCACATCATACGCCGGGTGATGATGTTTTGGGGGAAGGCCAAC
CGATCATCATCGATATGGGGGCCCGTCTTGATGGCTACCACGCCGATTTGACTCGCACGATTGTGCTCGGTCAACCCGAC
GACACCTTTCGAGCAGTGTATGCGGCAACCCTCAAGGCACAACAGGCTGCCATGCAAGCCCTTCGCCCTGGATTACCGTG
GTCTGAAGCTGATGCCATCGCTCGCCGCGTTATCGGTGAGGCCGGCTACGCTGAAGGCATCGCGCACAGCCTCGGCCACG
GCGTTGGTCTGGTGATCCATGAAGCACCCTGGCTCCGAATTACCGCCCCTGACGCACCTCCCAGTCCGCCGTTGCAGGCC
GGAATGGTGACTTCTATCGAACCGGGCATCTACCTGCCGGAATGGGGTGGGGTGCGGATTGAGGATTTGGTCCTCATCAC
GACCAATGGTTACGAGGTGTTGTCACAGGCACCGAAGTAA

Upstream 100 bases:

>100_bases
CTCCGCACATAGCCAGCCTGACCGGTTTGTCACACACTCTGCATATATGGTGTAGGATAACAGGGTCACACGATTACGTG
GAAAGACGAAAGGACAGATA

Downstream 100 bases:

>100_bases
TCAGGCACTTGCCACACAAGATCGCCAGCCACCCTGATCCTGGGACGCCACAGGGTAGCCTGTGGCGTTTCAACCAGCAA
GTGGTTATCGCCGTACACAC

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MTNRLQQLRATLAARELPAMLLTAPTSRRYISGFTGSAGALLISAEAAFLLTDGRYLIRAAAEAPHFTLREVRPPARPMT
ALIADLASELGIKRLGFEAAVMTVAEHRQYTAALGNAIELVPTENIVEELRMVKDEEEIALLRRAAAITDAALAAVLPAL
TPTMTEREAAWRLEVALHDLGAEGPSFPIIVAAGRNSARPHHTPGDDVLGEGQPIIIDMGARLDGYHADLTRTIVLGQPD
DTFRAVYAATLKAQQAAMQALRPGLPWSEADAIARRVIGEAGYAEGIAHSLGHGVGLVIHEAPWLRITAPDAPPSPPLQA
GMVTSIEPGIYLPEWGGVRIEDLVLITTNGYEVLSQAPK

Sequences:

>Translated_359_residues
MTNRLQQLRATLAARELPAMLLTAPTSRRYISGFTGSAGALLISAEAAFLLTDGRYLIRAAAEAPHFTLREVRPPARPMT
ALIADLASELGIKRLGFEAAVMTVAEHRQYTAALGNAIELVPTENIVEELRMVKDEEEIALLRRAAAITDAALAAVLPAL
TPTMTEREAAWRLEVALHDLGAEGPSFPIIVAAGRNSARPHHTPGDDVLGEGQPIIIDMGARLDGYHADLTRTIVLGQPD
DTFRAVYAATLKAQQAAMQALRPGLPWSEADAIARRVIGEAGYAEGIAHSLGHGVGLVIHEAPWLRITAPDAPPSPPLQA
GMVTSIEPGIYLPEWGGVRIEDLVLITTNGYEVLSQAPK
>Mature_358_residues
TNRLQQLRATLAARELPAMLLTAPTSRRYISGFTGSAGALLISAEAAFLLTDGRYLIRAAAEAPHFTLREVRPPARPMTA
LIADLASELGIKRLGFEAAVMTVAEHRQYTAALGNAIELVPTENIVEELRMVKDEEEIALLRRAAAITDAALAAVLPALT
PTMTEREAAWRLEVALHDLGAEGPSFPIIVAAGRNSARPHHTPGDDVLGEGQPIIIDMGARLDGYHADLTRTIVLGQPDD
TFRAVYAATLKAQQAAMQALRPGLPWSEADAIARRVIGEAGYAEGIAHSLGHGVGLVIHEAPWLRITAPDAPPSPPLQAG
MVTSIEPGIYLPEWGGVRIEDLVLITTNGYEVLSQAPK

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=265, Percent_Identity=27.5471698113208, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI260593665, Length=289, Percent_Identity=26.643598615917, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI149589008, Length=289, Percent_Identity=26.643598615917, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI40385867, Length=251, Percent_Identity=27.8884462151394, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI260593663, Length=236, Percent_Identity=26.6949152542373, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI93141226, Length=251, Percent_Identity=29.8804780876494, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI264681563, Length=167, Percent_Identity=32.9341317365269, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1788728, Length=360, Percent_Identity=35.2777777777778, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1789275, Length=276, Percent_Identity=29.3478260869565, Blast_Score=105, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17508215, Length=291, Percent_Identity=27.8350515463918, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17509539, Length=367, Percent_Identity=24.5231607629428, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321118, Length=344, Percent_Identity=25.2906976744186, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6320922, Length=260, Percent_Identity=25, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322999, Length=234, Percent_Identity=28.6324786324786, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357079, Length=293, Percent_Identity=29.3515358361775, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17137632, Length=168, Percent_Identity=32.1428571428571, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38372; Mature: 38240

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRLQQLRATLAARELPAMLLTAPTSRRYISGFTGSAGALLISAEAAFLLTDGRYLIRA
CCHHHHHHHHHHHHHHCCCEEEECCCCCHHCCCCCCCCCEEEEECCEEEEEECCCEEEEE
AAEAPHFTLREVRPPARPMTALIADLASELGIKRLGFEAAVMTVAEHRQYTAALGNAIEL
CCCCCCEEHHHCCCCCHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHCCEEEE
VPTENIVEELRMVKDEEEIALLRRAAAITDAALAAVLPALTPTMTEREAAWRLEVALHDL
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEHHHHC
GAEGPSFPIIVAAGRNSARPHHTPGDDVLGEGQPIIIDMGARLDGYHADLTRTIVLGQPD
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEECCEEEEEEECCCC
DTFRAVYAATLKAQQAAMQALRPGLPWSEADAIARRVIGEAGYAEGIAHSLGHGVGLVIH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEE
EAPWLRITAPDAPPSPPLQAGMVTSIEPGIYLPEWGGVRIEDLVLITTNGYEVLSQAPK
CCCEEEEECCCCCCCCCCCCCCEEECCCCEECCCCCCCEEEEEEEEEECCHHHHHCCCC
>Mature Secondary Structure 
TNRLQQLRATLAARELPAMLLTAPTSRRYISGFTGSAGALLISAEAAFLLTDGRYLIRA
CHHHHHHHHHHHHHHCCCEEEECCCCCHHCCCCCCCCCEEEEECCEEEEEECCCEEEEE
AAEAPHFTLREVRPPARPMTALIADLASELGIKRLGFEAAVMTVAEHRQYTAALGNAIEL
CCCCCCEEHHHCCCCCHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHCCEEEE
VPTENIVEELRMVKDEEEIALLRRAAAITDAALAAVLPALTPTMTEREAAWRLEVALHDL
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEHHHHC
GAEGPSFPIIVAAGRNSARPHHTPGDDVLGEGQPIIIDMGARLDGYHADLTRTIVLGQPD
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEECCEEEEEEECCCC
DTFRAVYAATLKAQQAAMQALRPGLPWSEADAIARRVIGEAGYAEGIAHSLGHGVGLVIH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEE
EAPWLRITAPDAPPSPPLQAGMVTSIEPGIYLPEWGGVRIEDLVLITTNGYEVLSQAPK
CCCEEEEECCCCCCCCCCCCCCEEECCCCEECCCCCCCEEEEEEEEEECCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]