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The map label for this gene is ktrB [H]

Identifier: 222523516

GI number: 222523516

Start: 264674

End: 266050

Strand: Direct

Name: ktrB [H]

Synonym: Chy400_0222

Alternate gene names: 222523516

Gene position: 264674-266050 (Clockwise)

Preceding gene: 222523515

Following gene: 222523517

Centisome position: 5.02

GC content: 56.5

Gene sequence:

>1377_bases
ATGACAGCACTTGTTACTGGCCGCAATCTGGCTCGATTGCGGCGTAAGCCGATCCCACCACCTCTCCGGCTGGTCGGTGG
GTTAGCCTTGTTAATCGTTATTGGCACGCTGCTACTGCTGCTTCCAATTAGCAGTACCCGGCCACTCACATTTATGGAAG
CCCTGTTTACGGCGGCTTCAGCGTTAAGCGTGACCGGTTTATCGGTCATTACGCCGGTACAAGACCTCTCGCTGGTAGGG
CAAATCTTGCTGATGTTGCTTATCCAGATTGGCGGTGTCGGGTTCATGGTGGTAGCCGTGATCATCTTCCGCCTGCTCGG
TCGGCGAATCAGCTTTACCGACCGGATTGCCCTAAGCGACTCGCTGGGTCTGCTCTCGCCGGCAGCAATCGTCACGCTCA
CGCGGCGCGTGCTGATCACCGTAGTAACTATCGAAGCCATTGGCGCCATGCTGCTCTACATCCACTGGCGTACCGATCCC
CGCCTCAGTGAAGGTCAGGCATTCTTCTATGCCCTGTTCCACGCTGTTTCTGCATTTTGTAACGCTGGATTTGACCTCTT
CACCGGCACGCCCGGTTTTGAAAACGGTATTCCACGTGATAGTATTACCCTGTTTATTATGGGAATGCTGATCCTGACCG
GCGGTCTGGGGATTCCAGTGATTGCAGACCTGATTTCGTATGCCAACGAACGCAAGCTCTCGCTGCACACGCGCATCACC
CTGCTCGTGGTGAGCTTCCTGGTCGGGATAGGCACGTTCGGTCTCTGGCTCAGTGAGGGCTTCGACGCCGACGGCACCCT
CCACGGCCAACCGCTCGACCGCCAGCTTATTGTGACCACCTTTCAATCGATCTCAGCCCGTACTGCCGGCTTTTCCGGCA
TGGATAGCTTTGAATCGTTGACGCCTGCCAGTCAGTTGTTGCTCATTGCACTCATGTTCATTGGTTGTGCGCCGGCATCA
ATGGGAGGCGGCATCACGACCGGCACCTTTGCCGTACTGTCAATCTCGCTGTGGAGCTACGCCCGTGGCTTGCCAACCGC
GCAGTTTGCCGGGCGCAGCCTGGCTACCGGCATGGTACGCCGGGCCGCCGCCGTGCTCACCATCTCTCTCTTTGTTGTTC
TCCTTGCATCCTGGCTCATTGTCGCCACCCATGATGCAACTCTTGACCAGGTTGTGTTTGAGGTGGTGTCGGCATTTGCC
ACCTGTGGCCTCACCCTCGGTTTTACCAGTGAGCTAAACACGTTTGGTCAGCTTATCATCATTGCGGTGATGTTTTGGGG
ACGCCTGGGGGCACTTACCATCATTACCGCCATAGCCCGCCAGAGCGCGACTCCACAACAGATCACCTATCCCGAAGAGC
AAATCCTGATCGGATAA

Upstream 100 bases:

>100_bases
TGATTGTCACCCCACCACCCGACTATGTCTTCAGCCGCGATGATCGGATTCTGATTATTGGCGCCGATTCGAGTATCAGC
ACCTTCTGCGATCTATCATC

Downstream 100 bases:

>100_bases
CCTATGCGTCACCTGTACCTGCACATTCCCTTCTGTCACCGGCGCTGCTCCTATTGCGATTTTAACACCTACGCCAACAT
GGAGCACCGGATTGAAGCGT

Product: H(+)-transporting two-sector ATPase

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: K(+)-uptake protein ktrB [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTALVTGRNLARLRRKPIPPPLRLVGGLALLIVIGTLLLLLPISSTRPLTFMEALFTAASALSVTGLSVITPVQDLSLVG
QILLMLLIQIGGVGFMVVAVIIFRLLGRRISFTDRIALSDSLGLLSPAAIVTLTRRVLITVVTIEAIGAMLLYIHWRTDP
RLSEGQAFFYALFHAVSAFCNAGFDLFTGTPGFENGIPRDSITLFIMGMLILTGGLGIPVIADLISYANERKLSLHTRIT
LLVVSFLVGIGTFGLWLSEGFDADGTLHGQPLDRQLIVTTFQSISARTAGFSGMDSFESLTPASQLLLIALMFIGCAPAS
MGGGITTGTFAVLSISLWSYARGLPTAQFAGRSLATGMVRRAAAVLTISLFVVLLASWLIVATHDATLDQVVFEVVSAFA
TCGLTLGFTSELNTFGQLIIIAVMFWGRLGALTIITAIARQSATPQQITYPEEQILIG

Sequences:

>Translated_458_residues
MTALVTGRNLARLRRKPIPPPLRLVGGLALLIVIGTLLLLLPISSTRPLTFMEALFTAASALSVTGLSVITPVQDLSLVG
QILLMLLIQIGGVGFMVVAVIIFRLLGRRISFTDRIALSDSLGLLSPAAIVTLTRRVLITVVTIEAIGAMLLYIHWRTDP
RLSEGQAFFYALFHAVSAFCNAGFDLFTGTPGFENGIPRDSITLFIMGMLILTGGLGIPVIADLISYANERKLSLHTRIT
LLVVSFLVGIGTFGLWLSEGFDADGTLHGQPLDRQLIVTTFQSISARTAGFSGMDSFESLTPASQLLLIALMFIGCAPAS
MGGGITTGTFAVLSISLWSYARGLPTAQFAGRSLATGMVRRAAAVLTISLFVVLLASWLIVATHDATLDQVVFEVVSAFA
TCGLTLGFTSELNTFGQLIIIAVMFWGRLGALTIITAIARQSATPQQITYPEEQILIG
>Mature_457_residues
TALVTGRNLARLRRKPIPPPLRLVGGLALLIVIGTLLLLLPISSTRPLTFMEALFTAASALSVTGLSVITPVQDLSLVGQ
ILLMLLIQIGGVGFMVVAVIIFRLLGRRISFTDRIALSDSLGLLSPAAIVTLTRRVLITVVTIEAIGAMLLYIHWRTDPR
LSEGQAFFYALFHAVSAFCNAGFDLFTGTPGFENGIPRDSITLFIMGMLILTGGLGIPVIADLISYANERKLSLHTRITL
LVVSFLVGIGTFGLWLSEGFDADGTLHGQPLDRQLIVTTFQSISARTAGFSGMDSFESLTPASQLLLIALMFIGCAPASM
GGGITTGTFAVLSISLWSYARGLPTAQFAGRSLATGMVRRAAAVLTISLFVVLLASWLIVATHDATLDQVVFEVVSAFAT
CGLTLGFTSELNTFGQLIIIAVMFWGRLGALTIITAIARQSATPQQITYPEEQILIG

Specific function: Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family. Ktr (TC 2.A.38.4) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 48845; Mature: 48714

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALVTGRNLARLRRKPIPPPLRLVGGLALLIVIGTLLLLLPISSTRPLTFMEALFTAAS
CCEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ALSVTGLSVITPVQDLSLVGQILLMLLIQIGGVGFMVVAVIIFRLLGRRISFTDRIALSD
HHHHCCHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHEECC
SLGLLSPAAIVTLTRRVLITVVTIEAIGAMLLYIHWRTDPRLSEGQAFFYALFHAVSAFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHH
NAGFDLFTGTPGFENGIPRDSITLFIMGMLILTGGLGIPVIADLISYANERKLSLHTRIT
HCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHH
LLVVSFLVGIGTFGLWLSEGFDADGTLHGQPLDRQLIVTTFQSISARTAGFSGMDSFESL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHC
TPASQLLLIALMFIGCAPASMGGGITTGTFAVLSISLWSYARGLPTAQFAGRSLATGMVR
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHH
RAAAVLTISLFVVLLASWLIVATHDATLDQVVFEVVSAFATCGLTLGFTSELNTFGQLII
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
IAVMFWGRLGALTIITAIARQSATPQQITYPEEQILIG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECC
>Mature Secondary Structure 
TALVTGRNLARLRRKPIPPPLRLVGGLALLIVIGTLLLLLPISSTRPLTFMEALFTAAS
CEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ALSVTGLSVITPVQDLSLVGQILLMLLIQIGGVGFMVVAVIIFRLLGRRISFTDRIALSD
HHHHCCHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHEECC
SLGLLSPAAIVTLTRRVLITVVTIEAIGAMLLYIHWRTDPRLSEGQAFFYALFHAVSAFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHH
NAGFDLFTGTPGFENGIPRDSITLFIMGMLILTGGLGIPVIADLISYANERKLSLHTRIT
HCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHH
LLVVSFLVGIGTFGLWLSEGFDADGTLHGQPLDRQLIVTTFQSISARTAGFSGMDSFESL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHC
TPASQLLLIALMFIGCAPASMGGGITTGTFAVLSISLWSYARGLPTAQFAGRSLATGMVR
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHH
RAAAVLTISLFVVLLASWLIVATHDATLDQVVFEVVSAFATCGLTLGFTSELNTFGQLII
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
IAVMFWGRLGALTIITAIARQSATPQQITYPEEQILIG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]