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The map label for this gene is 222523429

Identifier: 222523429

GI number: 222523429

Start: 162276

End: 163475

Strand: Direct

Name: 222523429

Synonym: Chy400_0132

Alternate gene names: NA

Gene position: 162276-163475 (Clockwise)

Preceding gene: 222523428

Following gene: 222523430

Centisome position: 3.08

GC content: 57.83

Gene sequence:

>1200_bases
ATGCGCACTCTAATCTTCACCGGCAAAGGTGGCGTTGGCAAGACAAGTGTCGCCGCAGCAACAGCTCTCCGGGCCGCCGA
TCGAGGCTTGAAGACGCTAGTCATGAGCACCGATCCGGCCCACTCGCTGGCCGACTCGCTCGATCTGGAAGGGCCACTCG
GCCCGGAACCGGTTCGGATTACCAAAAACCTCGATGCGCTTGAAGTGAGCATTTATCACGATATCGAGAGCAACTGGGGT
ATCGTGCGTGAGCACTTCGCGCAACTGATGGCCGAGCAGGGCGTACAGGGCATTCTGGCCGACGAGATGAGCGTCCTGCC
AGGTATGGAAGAGGCTTTTCCGCTCATCCGCATCAAGAAACACAAAGAGCGTGGCGACTACGATCTCCTGGTGATCGACT
GCGCACCAACGGGAGAAACGCTGCGCCTGCTCTCAGCCCCCGAGACGTTCAAATGGGCAATCAACATGCTACGCGGTGCC
GAGCGCTACGTCATCAGGCCGTTGATCCGGCCCATGAGCAAGATTACGCCCGGCCTTAACAAAATGGTTGCCCCACCCGA
AGTCTATGATGCGGTTGATGAGATGTTCCGCCAGATGGAGGGGGTAACGGCAACACTGGCCAACCCGCGGGAGACATCGA
TCCGCCTGGTGATGAACCCGGAAAAGATGGTCATCAAAGAGAGCCAGCGCGCCTTAACCTACCTGTCGATGTACGGTATG
ACCGTCGATATGGTAGTGGTGAACAAGATTTTGCCCCTCGATCAGGATAGCGGCTATCTGAACCACTGGCGCGATGTGCA
ACAGCGCTATCTCCAGGATGTTGAACATGCCTTCGTGCCGTTGCCTATCCGGCGGGTACCGTACTATCCCGAAGAAGTGG
TGGGCCTGGAGAAGCTACGCCAGATGGGAGATGACATTTACGGCGATATGGATCCAACTGCCGTGCTCTACGACCGGGCA
CCGCTGGACATTGCCAAAGTTGGTGATAAATCGTACCGGGTCAAGATCCGCCTGCCATTCGCTGATGTGTCGCAGCTCGA
TCTGTATCAGAACGGCGACGAGCTGGTGATACAGATCGGCGACTTCCGGCGGGTCATTACGCTGCCGACCAGTCTGGCCG
GCCTGGAAGCCGGTCAGGCCGAGATGGAGGGTGAATGGTTGATTGTCCCCTTCATGGCGCCGCAAATGGCGCAACGCTGA

Upstream 100 bases:

>100_bases
TTTTAAGCAAAAACTTCATGTCGTGTTCGATTGCAGACCTCATTAACACCGTTTTGTGGCGGTCGTTACTAGCCGAGCAG
TAGCTCCTGGAAAGGCCCTG

Downstream 100 bases:

>100_bases
GGCAGCCTGAACTGTGGGGTTTCTCGGAGGCTTGCCTCCGGTGACCTGAATAATGGAGTCCGTTTGATAAGGAGGTGTGT
GCATGGCGACGAGAGGCTGG

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MRTLIFTGKGGVGKTSVAAATALRAADRGLKTLVMSTDPAHSLADSLDLEGPLGPEPVRITKNLDALEVSIYHDIESNWG
IVREHFAQLMAEQGVQGILADEMSVLPGMEEAFPLIRIKKHKERGDYDLLVIDCAPTGETLRLLSAPETFKWAINMLRGA
ERYVIRPLIRPMSKITPGLNKMVAPPEVYDAVDEMFRQMEGVTATLANPRETSIRLVMNPEKMVIKESQRALTYLSMYGM
TVDMVVVNKILPLDQDSGYLNHWRDVQQRYLQDVEHAFVPLPIRRVPYYPEEVVGLEKLRQMGDDIYGDMDPTAVLYDRA
PLDIAKVGDKSYRVKIRLPFADVSQLDLYQNGDELVIQIGDFRRVITLPTSLAGLEAGQAEMEGEWLIVPFMAPQMAQR

Sequences:

>Translated_399_residues
MRTLIFTGKGGVGKTSVAAATALRAADRGLKTLVMSTDPAHSLADSLDLEGPLGPEPVRITKNLDALEVSIYHDIESNWG
IVREHFAQLMAEQGVQGILADEMSVLPGMEEAFPLIRIKKHKERGDYDLLVIDCAPTGETLRLLSAPETFKWAINMLRGA
ERYVIRPLIRPMSKITPGLNKMVAPPEVYDAVDEMFRQMEGVTATLANPRETSIRLVMNPEKMVIKESQRALTYLSMYGM
TVDMVVVNKILPLDQDSGYLNHWRDVQQRYLQDVEHAFVPLPIRRVPYYPEEVVGLEKLRQMGDDIYGDMDPTAVLYDRA
PLDIAKVGDKSYRVKIRLPFADVSQLDLYQNGDELVIQIGDFRRVITLPTSLAGLEAGQAEMEGEWLIVPFMAPQMAQR
>Mature_399_residues
MRTLIFTGKGGVGKTSVAAATALRAADRGLKTLVMSTDPAHSLADSLDLEGPLGPEPVRITKNLDALEVSIYHDIESNWG
IVREHFAQLMAEQGVQGILADEMSVLPGMEEAFPLIRIKKHKERGDYDLLVIDCAPTGETLRLLSAPETFKWAINMLRGA
ERYVIRPLIRPMSKITPGLNKMVAPPEVYDAVDEMFRQMEGVTATLANPRETSIRLVMNPEKMVIKESQRALTYLSMYGM
TVDMVVVNKILPLDQDSGYLNHWRDVQQRYLQDVEHAFVPLPIRRVPYYPEEVVGLEKLRQMGDDIYGDMDPTAVLYDRA
PLDIAKVGDKSYRVKIRLPFADVSQLDLYQNGDELVIQIGDFRRVITLPTSLAGLEAGQAEMEGEWLIVPFMAPQMAQR

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=289, Percent_Identity=24.5674740484429, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17557003, Length=282, Percent_Identity=25.177304964539, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320103, Length=325, Percent_Identity=23.3846153846154, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586297, Length=311, Percent_Identity=25.08038585209, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 44740; Mature: 44740

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLIFTGKGGVGKTSVAAATALRAADRGLKTLVMSTDPAHSLADSLDLEGPLGPEPVRI
CCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCCCCEEE
TKNLDALEVSIYHDIESNWGIVREHFAQLMAEQGVQGILADEMSVLPGMEEAFPLIRIKK
ECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCEEEEE
HKERGDYDLLVIDCAPTGETLRLLSAPETFKWAINMLRGAERYVIRPLIRPMSKITPGLN
CCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCH
KMVAPPEVYDAVDEMFRQMEGVTATLANPRETSIRLVMNPEKMVIKESQRALTYLSMYGM
HCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
TVDMVVVNKILPLDQDSGYLNHWRDVQQRYLQDVEHAFVPLPIRRVPYYPEEVVGLEKLR
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHH
QMGDDIYGDMDPTAVLYDRAPLDIAKVGDKSYRVKIRLPFADVSQLDLYQNGDELVIQIG
HHHHHHCCCCCCCEEEECCCCCCHHHCCCCEEEEEEEECCCCCCHHHHHCCCCEEEEEEC
DFRRVITLPTSLAGLEAGQAEMEGEWLIVPFMAPQMAQR
CCEEEEECCCHHHCCCCCCCCCCCCEEEEEECCHHHHCC
>Mature Secondary Structure
MRTLIFTGKGGVGKTSVAAATALRAADRGLKTLVMSTDPAHSLADSLDLEGPLGPEPVRI
CCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCCCCEEE
TKNLDALEVSIYHDIESNWGIVREHFAQLMAEQGVQGILADEMSVLPGMEEAFPLIRIKK
ECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCEEEEE
HKERGDYDLLVIDCAPTGETLRLLSAPETFKWAINMLRGAERYVIRPLIRPMSKITPGLN
CCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCH
KMVAPPEVYDAVDEMFRQMEGVTATLANPRETSIRLVMNPEKMVIKESQRALTYLSMYGM
HCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
TVDMVVVNKILPLDQDSGYLNHWRDVQQRYLQDVEHAFVPLPIRRVPYYPEEVVGLEKLR
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHH
QMGDDIYGDMDPTAVLYDRAPLDIAKVGDKSYRVKIRLPFADVSQLDLYQNGDELVIQIG
HHHHHHCCCCCCCEEEECCCCCCHHHCCCCEEEEEEEECCCCCCHHHHHCCCCEEEEEEC
DFRRVITLPTSLAGLEAGQAEMEGEWLIVPFMAPQMAQR
CCEEEEECCCHHHCCCCCCCCCCCCEEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]