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The map label for this gene is ideR [H]

Identifier: 222523405

GI number: 222523405

Start: 134479

End: 135180

Strand: Reverse

Name: ideR [H]

Synonym: Chy400_0107

Alternate gene names: 222523405

Gene position: 135180-134479 (Counterclockwise)

Preceding gene: 222523415

Following gene: 222523403

Centisome position: 2.57

GC content: 59.83

Gene sequence:

>702_bases
TTGACCCCAGTAGAAGACCCTAACCTGCCCGGTCGGATTACGCCGGCAATTGAAGATTATCTGAAAGCTATCTACCTGCT
CCAGCAGCAGGTCGGTGCGGTGACGACGACCTTGCTCGGTGAGCAGCGTGGTTCGCGACCCGCATCGGTCACCGGTATGA
TTAAAAAGCTGGCCGAGATGAATCTGGTGCAGCATACTCCGTACCAGGGCGTGATCTTGACGCCAGCCGGTGAGCGGATT
GCGCTTGAAGTGATTCGGCATCATCGCCTGCTCGAACTCTATCTGGTGGAGGCCCTCGGCTATAGCTGGGACGAGGTTCA
TGAAGAGGCTGAGCGGCTGGAACATCATATCAGCGAGAAACTTGAAGCCCGGATCGCCGAGCGATTGGGGTTTCCCGATT
TTGATCCGCATGGCGATCCAATCCCAGGCATTGATGGTGTCTTGCCGACCACACGGGCGATCCGCCTAGCCGATCTGCCG
CTCAATCAGGTAGCCCGGATCGTGCGGGTGCGCGATCAGGCGGCTGAGCGGTTGCGATACCTGGCCGACCTTGGGCTGGT
GCCTGGGGCACGGGTCACAGTGGTAGCGAGTGCGCCTTTCGATGGCCCACTGACGGTGCAGATCGGGACGAATGAGCCAA
CACCGCTCGACCGTCGGTTGGCGCGCACGATTGAGGTTGAGGTGGAGTCAGAGGCTGCGTGA

Upstream 100 bases:

>100_bases
GCTCTCGATTGTACCACGCCCGTTGCACGAAGTAACCGCTCTATGGTACATTGAAGCCAGGAAAAGCCGGGTTGCTCGCG
CCACCAAAAGGAGACGCGCC

Downstream 100 bases:

>100_bases
TGTGGGCAAGGGGGAGCGTTCTTCTTCGTTGTGCTTCCGAAGGTGCACCACAGAGACACAGAGAGCACAGAGGGATGTAG
TGCTGCGGCATGTTTTCCTC

Product: DtxR family iron (metal) dependent repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTPVEDPNLPGRITPAIEDYLKAIYLLQQQVGAVTTTLLGEQRGSRPASVTGMIKKLAEMNLVQHTPYQGVILTPAGERI
ALEVIRHHRLLELYLVEALGYSWDEVHEEAERLEHHISEKLEARIAERLGFPDFDPHGDPIPGIDGVLPTTRAIRLADLP
LNQVARIVRVRDQAAERLRYLADLGLVPGARVTVVASAPFDGPLTVQIGTNEPTPLDRRLARTIEVEVESEAA

Sequences:

>Translated_233_residues
MTPVEDPNLPGRITPAIEDYLKAIYLLQQQVGAVTTTLLGEQRGSRPASVTGMIKKLAEMNLVQHTPYQGVILTPAGERI
ALEVIRHHRLLELYLVEALGYSWDEVHEEAERLEHHISEKLEARIAERLGFPDFDPHGDPIPGIDGVLPTTRAIRLADLP
LNQVARIVRVRDQAAERLRYLADLGLVPGARVTVVASAPFDGPLTVQIGTNEPTPLDRRLARTIEVEVESEAA
>Mature_232_residues
TPVEDPNLPGRITPAIEDYLKAIYLLQQQVGAVTTTLLGEQRGSRPASVTGMIKKLAEMNLVQHTPYQGVILTPAGERIA
LEVIRHHRLLELYLVEALGYSWDEVHEEAERLEHHISEKLEARIAERLGFPDFDPHGDPIPGIDGVLPTTRAIRLADLPL
NQVARIVRVRDQAAERLRYLADLGLVPGARVTVVASAPFDGPLTVQIGTNEPTPLDRRLARTIEVEVESEAA

Specific function: Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism [H]

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787038, Length=104, Percent_Identity=35.5769230769231, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007167
- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR008988
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress; PF04023 FeoA [H]

EC number: NA

Molecular weight: Translated: 25743; Mature: 25612

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50944 HTH_DTXR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVEDPNLPGRITPAIEDYLKAIYLLQQQVGAVTTTLLGEQRGSRPASVTGMIKKLAEM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
NLVQHTPYQGVILTPAGERIALEVIRHHRLLELYLVEALGYSWDEVHEEAERLEHHISEK
HHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LEARIAERLGFPDFDPHGDPIPGIDGVLPTTRAIRLADLPLNQVARIVRVRDQAAERLRY
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
LADLGLVPGARVTVVASAPFDGPLTVQIGTNEPTPLDRRLARTIEVEVESEAA
HHHHCCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHEEEECCCCC
>Mature Secondary Structure 
TPVEDPNLPGRITPAIEDYLKAIYLLQQQVGAVTTTLLGEQRGSRPASVTGMIKKLAEM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
NLVQHTPYQGVILTPAGERIALEVIRHHRLLELYLVEALGYSWDEVHEEAERLEHHISEK
HHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LEARIAERLGFPDFDPHGDPIPGIDGVLPTTRAIRLADLPLNQVARIVRVRDQAAERLRY
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
LADLGLVPGARVTVVASAPFDGPLTVQIGTNEPTPLDRRLARTIEVEVESEAA
HHHHCCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]