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The map label for this gene is kdgR [H]

Identifier: 222523404

GI number: 222523404

Start: 132503

End: 133294

Strand: Direct

Name: kdgR [H]

Synonym: Chy400_0106

Alternate gene names: 222523404

Gene position: 132503-133294 (Clockwise)

Preceding gene: 222523401

Following gene: 222523406

Centisome position: 2.51

GC content: 60.23

Gene sequence:

>792_bases
TTGAATGGTGAAAAGCGTATGGTACAGTCACTGGATCGTGCCTTCGATGTACTGGAAGCATTGGCCTTCGCCGACGACGA
CTTAAGTGTCTCCGAGCTAAGCGAGCAGCTTGATCTCCCCCTTGCCACCGTCCATCGGCTGCTCTCTAGTTTAGCCGCAC
GTGGCTATGTTACGCAAGAGGCAAGCACCCGCCGCTACGGGCCGGGGCCGCGGCTGTTGGAAGTCGCGGCCCGCGCTGCC
CGCAGTCGTCGTTTTGACCTGATTCGCATTGCCCGCGCCGAACTGGTGAAACTGACCGCCGAGACCGGTGAGACCAGCAA
TCTGATCGTTCGCCAGGGCGACCTCGCCGTTTACCAGGAACAGATTCCCAGCCCGCATATGGTACGGATGTTCACCGAAA
TCGGTCAACGGGCACCACTCTACTGTACCGGCGGTGGTAAAGCCATTCTGTCTGCGCTACCAATTGCCGAACTCGAACAG
TACCTTGCCGGCGGTCACTTCGAGCGTTGGACAAACAGGACGATTACCGACCCCGAACGTCTCCGCGCTGAACTCATGAC
TGCCCGCGAACGAGGGTTTGCTCTCGATGATGAAGAGCGCGAGGAGGGTGTGTGCTGCGTTGCCGCACCGATCTTCGACC
GCCGCGGACAGGTCGTTGGCGCGATCAGTCTGTCTGGCCCGTCCACCCGCCTCAACCGCGCAAGAGCCGAAGAACTGGGA
CCACGGGTGCGCGAAGCAGCATTGGCGTGTAGCCGGCAACTCGGCTTCCACACCACATTAACCGGCAAGTAA

Upstream 100 bases:

>100_bases
CAAGCATAGCGTTCATATGTTGCGCACCACAAATGTAAGTTTTGCTGTCCCAGTTGGCAAAAAAGACGACTTTCCATTAC
ACTATGATTGGAAAGAGGTT

Downstream 100 bases:

>100_bases
CTCGCCGGCTACGTGACAGGGGCAGAACGAGTCTTTCACTGCCACATAACTCTGCTCTCAAAACGGTCTTCTACGTCTGG
CAGAGATGCCCCTCTGTACC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNGEKRMVQSLDRAFDVLEALAFADDDLSVSELSEQLDLPLATVHRLLSSLAARGYVTQEASTRRYGPGPRLLEVAARAA
RSRRFDLIRIARAELVKLTAETGETSNLIVRQGDLAVYQEQIPSPHMVRMFTEIGQRAPLYCTGGGKAILSALPIAELEQ
YLAGGHFERWTNRTITDPERLRAELMTARERGFALDDEEREEGVCCVAAPIFDRRGQVVGAISLSGPSTRLNRARAEELG
PRVREAALACSRQLGFHTTLTGK

Sequences:

>Translated_263_residues
MNGEKRMVQSLDRAFDVLEALAFADDDLSVSELSEQLDLPLATVHRLLSSLAARGYVTQEASTRRYGPGPRLLEVAARAA
RSRRFDLIRIARAELVKLTAETGETSNLIVRQGDLAVYQEQIPSPHMVRMFTEIGQRAPLYCTGGGKAILSALPIAELEQ
YLAGGHFERWTNRTITDPERLRAELMTARERGFALDDEEREEGVCCVAAPIFDRRGQVVGAISLSGPSTRLNRARAEELG
PRVREAALACSRQLGFHTTLTGK
>Mature_263_residues
MNGEKRMVQSLDRAFDVLEALAFADDDLSVSELSEQLDLPLATVHRLLSSLAARGYVTQEASTRRYGPGPRLLEVAARAA
RSRRFDLIRIARAELVKLTAETGETSNLIVRQGDLAVYQEQIPSPHMVRMFTEIGQRAPLYCTGGGKAILSALPIAELEQ
YLAGGHFERWTNRTITDPERLRAELMTARERGFALDDEEREEGVCCVAAPIFDRRGQVVGAISLSGPSTRLNRARAEELG
PRVREAALACSRQLGFHTTLTGK

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=250, Percent_Identity=37.2, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI1786715, Length=252, Percent_Identity=36.1111111111111, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI87082359, Length=242, Percent_Identity=34.297520661157, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786468, Length=250, Percent_Identity=32.4, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1789999, Length=251, Percent_Identity=35.4581673306773, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1788581, Length=255, Percent_Identity=28.2352941176471, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790752, Length=249, Percent_Identity=26.9076305220884, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29034; Mature: 29034

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGEKRMVQSLDRAFDVLEALAFADDDLSVSELSEQLDLPLATVHRLLSSLAARGYVTQE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
ASTRRYGPGPRLLEVAARAARSRRFDLIRIARAELVKLTAETGETSNLIVRQGDLAVYQE
CCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHH
QIPSPHMVRMFTEIGQRAPLYCTGGGKAILSALPIAELEQYLAGGHFERWTNRTITDPER
HCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHCCHHHHHHHHCCCCHHHHCCCCCCCHHH
LRAELMTARERGFALDDEEREEGVCCVAAPIFDRRGQVVGAISLSGPSTRLNRARAEELG
HHHHHHHHHHCCCCCCCCHHHCCEEEEECCHHCCCCCEEEEEEECCCHHHHHHHHHHHHC
PRVREAALACSRQLGFHTTLTGK
HHHHHHHHHHHHHCCCCEECCCC
>Mature Secondary Structure
MNGEKRMVQSLDRAFDVLEALAFADDDLSVSELSEQLDLPLATVHRLLSSLAARGYVTQE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
ASTRRYGPGPRLLEVAARAARSRRFDLIRIARAELVKLTAETGETSNLIVRQGDLAVYQE
CCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHH
QIPSPHMVRMFTEIGQRAPLYCTGGGKAILSALPIAELEQYLAGGHFERWTNRTITDPER
HCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHCCHHHHHHHHCCCCHHHHCCCCCCCHHH
LRAELMTARERGFALDDEEREEGVCCVAAPIFDRRGQVVGAISLSGPSTRLNRARAEELG
HHHHHHHHHHCCCCCCCCHHHCCEEEEECCHHCCCCCEEEEEEECCCHHHHHHHHHHHHC
PRVREAALACSRQLGFHTTLTGK
HHHHHHHHHHHHHCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]