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The map label for this gene is pimB [H]

Identifier: 222523380

GI number: 222523380

Start: 93421

End: 94557

Strand: Direct

Name: pimB [H]

Synonym: Chy400_0081

Alternate gene names: 222523380

Gene position: 93421-94557 (Clockwise)

Preceding gene: 222523379

Following gene: 222523382

Centisome position: 1.77

GC content: 55.23

Gene sequence:

>1137_bases
ATGAAAATCCTCTTTATCGCACGCTATCACCACCCTACCACGCAACGTAAGGTAGAGTATCTGGCGCAGGCACCTGATAT
TGATCTGTGTCACATTGTGCCGGCGTACCAGCCCCAATCCGCCGATCTACGTCCACTCGATGAGCAGCGTCGGTATCGAC
AACTCACCATCCCAATGCTGGGAAGTGTTAGTGATCCGCACCGCGCACTGTACCGCACCGTGACATTTCATCTCCACCGC
TTTCGTCCCGACATCATTCACGCTGAAGAGGAGCCAGACAGTCTGAGTGCGTTGCAAATTGTCTGGGCACGCCGCATATG
GGCACCCCAGGCCCGGCTTTTACTCCACACCTGGCAGAATCAAGACCGTCGCAAGTCAAGGGCAGTGCGCTGGGTGATCC
GGCAAACGCTGGAGGCGGCTGATCTGGTCTTCTGTGCCAATAGTGAGGCGATCACGCTCTTGCGGCGATTTGGTTTTACC
GGACCGGCACCACTCCTGCCGGCAATTGGTGTGGATACAACGCTCTTTCGTCCATGCGCTGCATATAATGGCTTGTCAGA
GCAGTCTGCCGCGAAGTCTTCGTACACTATCGGCTATATTGGAAGACTGGTTTGGGAGAAGGGAATTGATCTCTTATTAC
AGGCGGTTGCCGCTTTGACCAGCGCGATGCCTGACAGGCAGATACAGGTATGGGTGACGGGGGCTGGGCCGCTGCAAGCT
GAATTACAGTCACTGGCACGACAACTTGGCATAGAAGAGCGGGTAGTCTGGAAAGGCGCACAACCTCCGCACGAGATCGC
AAAAATCTTATGTCACCTTGATGTACTTGTGTTGCCCAGCCGCACCACGAACGTCTGGAAGGAACAGCTCGGTCGCGTCT
TGCTGGAAGCAATGGCGTGCGGCGTCCCGGTCATCGGCTCGACATCAGGTGCCATTCCTGAAGTCATCGGAGATGCGGGA
TTGATCGTGCCCGAAGGAGATGTTCAGGCATTAACGCAAGCGCTGAAACATCTGCTTTCTACACCTGATCTGCGGCAAAC
GCTGGCGCAGCGTGGCCGTATACGCGCTGAAACATATTACACGCAACGTCATCTTGCGGAACAAACGCTTGCTATCTATC
GGGAGATCGTGGCTTGA

Upstream 100 bases:

>100_bases
AAACAACATTAGGGTTAGCGGTCGTATCAGCGGAACCTGCTGCGCATATCGTTGAGGAAAGAATTTCCAGGCTGTCTTTA
CCAATCCTTTCCCGACACCT

Downstream 100 bases:

>100_bases
GAGGTGGAACAGTAGGAAGCTGTTTTTGTCGATGTGAGATTACTATCAGGTCGAACAACAAGGCTCTGTTTCGGCAATAG
ATGATGGTGGCTTCGATGGA

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKILFIARYHHPTTQRKVEYLAQAPDIDLCHIVPAYQPQSADLRPLDEQRRYRQLTIPMLGSVSDPHRALYRTVTFHLHR
FRPDIIHAEEEPDSLSALQIVWARRIWAPQARLLLHTWQNQDRRKSRAVRWVIRQTLEAADLVFCANSEAITLLRRFGFT
GPAPLLPAIGVDTTLFRPCAAYNGLSEQSAAKSSYTIGYIGRLVWEKGIDLLLQAVAALTSAMPDRQIQVWVTGAGPLQA
ELQSLARQLGIEERVVWKGAQPPHEIAKILCHLDVLVLPSRTTNVWKEQLGRVLLEAMACGVPVIGSTSGAIPEVIGDAG
LIVPEGDVQALTQALKHLLSTPDLRQTLAQRGRIRAETYYTQRHLAEQTLAIYREIVA

Sequences:

>Translated_378_residues
MKILFIARYHHPTTQRKVEYLAQAPDIDLCHIVPAYQPQSADLRPLDEQRRYRQLTIPMLGSVSDPHRALYRTVTFHLHR
FRPDIIHAEEEPDSLSALQIVWARRIWAPQARLLLHTWQNQDRRKSRAVRWVIRQTLEAADLVFCANSEAITLLRRFGFT
GPAPLLPAIGVDTTLFRPCAAYNGLSEQSAAKSSYTIGYIGRLVWEKGIDLLLQAVAALTSAMPDRQIQVWVTGAGPLQA
ELQSLARQLGIEERVVWKGAQPPHEIAKILCHLDVLVLPSRTTNVWKEQLGRVLLEAMACGVPVIGSTSGAIPEVIGDAG
LIVPEGDVQALTQALKHLLSTPDLRQTLAQRGRIRAETYYTQRHLAEQTLAIYREIVA
>Mature_378_residues
MKILFIARYHHPTTQRKVEYLAQAPDIDLCHIVPAYQPQSADLRPLDEQRRYRQLTIPMLGSVSDPHRALYRTVTFHLHR
FRPDIIHAEEEPDSLSALQIVWARRIWAPQARLLLHTWQNQDRRKSRAVRWVIRQTLEAADLVFCANSEAITLLRRFGFT
GPAPLLPAIGVDTTLFRPCAAYNGLSEQSAAKSSYTIGYIGRLVWEKGIDLLLQAVAALTSAMPDRQIQVWVTGAGPLQA
ELQSLARQLGIEERVVWKGAQPPHEIAKILCHLDVLVLPSRTTNVWKEQLGRVLLEAMACGVPVIGSTSGAIPEVIGDAG
LIVPEGDVQALTQALKHLLSTPDLRQTLAQRGRIRAETYYTQRHLAEQTLAIYREIVA

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=185, Percent_Identity=28.6486486486486, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788357, Length=200, Percent_Identity=30.5, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17532709, Length=259, Percent_Identity=25.4826254826255, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI9755344, Length=194, Percent_Identity=25.2577319587629, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 42444; Mature: 42444

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILFIARYHHPTTQRKVEYLAQAPDIDLCHIVPAYQPQSADLRPLDEQRRYRQLTIPML
CEEEEEEECCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHEECCHHH
GSVSDPHRALYRTVTFHLHRFRPDIIHAEEEPDSLSALQIVWARRIWAPQARLLLHTWQN
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCC
QDRRKSRAVRWVIRQTLEAADLVFCANSEAITLLRRFGFTGPAPLLPAIGVDTTLFRPCA
HHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
AYNGLSEQSAAKSSYTIGYIGRLVWEKGIDLLLQAVAALTSAMPDRQIQVWVTGAGPLQA
HHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHH
ELQSLARQLGIEERVVWKGAQPPHEIAKILCHLDVLVLPSRTTNVWKEQLGRVLLEAMAC
HHHHHHHHHCCCHHEEECCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHC
GVPVIGSTSGAIPEVIGDAGLIVPEGDVQALTQALKHLLSTPDLRQTLAQRGRIRAETYY
CCCCCCCCCCCCHHHHCCCCEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHH
TQRHLAEQTLAIYREIVA
HHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKILFIARYHHPTTQRKVEYLAQAPDIDLCHIVPAYQPQSADLRPLDEQRRYRQLTIPML
CEEEEEEECCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHEECCHHH
GSVSDPHRALYRTVTFHLHRFRPDIIHAEEEPDSLSALQIVWARRIWAPQARLLLHTWQN
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCC
QDRRKSRAVRWVIRQTLEAADLVFCANSEAITLLRRFGFTGPAPLLPAIGVDTTLFRPCA
HHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
AYNGLSEQSAAKSSYTIGYIGRLVWEKGIDLLLQAVAALTSAMPDRQIQVWVTGAGPLQA
HHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHH
ELQSLARQLGIEERVVWKGAQPPHEIAKILCHLDVLVLPSRTTNVWKEQLGRVLLEAMAC
HHHHHHHHHCCCHHEEECCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHC
GVPVIGSTSGAIPEVIGDAGLIVPEGDVQALTQALKHLLSTPDLRQTLAQRGRIRAETYY
CCCCCCCCCCCCHHHHCCCCEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHH
TQRHLAEQTLAIYREIVA
HHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA