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The map label for this gene is galE [H]

Identifier: 222523363

GI number: 222523363

Start: 68794

End: 69777

Strand: Direct

Name: galE [H]

Synonym: Chy400_0064

Alternate gene names: 222523363

Gene position: 68794-69777 (Clockwise)

Preceding gene: 222523362

Following gene: 222523364

Centisome position: 1.31

GC content: 55.28

Gene sequence:

>984_bases
ATGAGAATTTTAGTTACCGGTGGTGCCGGCTATATCGGCAGCATTACCAGCGCCGAGCTTATACGTGCCGGGCACGAGGT
GATTGTTATCGATAATCTGTATCAGGGTCATCGGGCCGCAGTACCGCCAGAGGCCACCTTTATCCAGGCCGATCTCGCCA
ACCGGCAGGAGTTGAGCGAGATTTTTGCAGCGTACCCAGGCATTGACGGTATTATGCATTTTGCTTCGTATACGCTGGTT
GGCGAAAGCATGGAAAAACCCATGCTGTATCTGCGTGATAATGTGACCAATGCGGGCAATCTGCTCGAAGTTGCGATTGC
TGCCGGGGTGCGTCGCTTTATTCTCTCGTCCACGGCCAATCTGTTTGACCAGCCGGAGCGGATTCCGATTGCTGAACATG
AACGGATTGTGCCCGGCTCACCTTACGGTGAGTCAAAGTTCTTTATTGAGCGGATGCTGCACTGGATGGCGCGTATTTAC
GGGATGCGCTACGCCTGTTTGCGTTACTTTAACGCCTGTGGCGATACGCCTGAACGAGGTGAGGATCACGACCCTGAAAC
CCATTTGATCCCAATCGTGTTGCAGGTAGCCCTCGGCCAACGCCCACACGTCACGATTTTCGGTGATGATTACCCAACAC
GCGATGGCACCTGTGTCCGCGACTATATCCACGTGCTCGATCTGGCAAGTGCGCACATTCTGGCGATGGAGGCGCTTGAT
CGGCTGGGTGAGCGACGCTATAATCTGGGAAATGGACAGGGATTTACGGTGCGCGAAGTCATTGAAACGGCGCGCAAAGT
TACCGGTCACCCAATCCCGGCAGTCGTAGGCCCGCGTCGACCAGGCGATCCGGCAGTACTGGTGGCTTCTTCCGAGACGA
TTCGGGCTGAGCTGGGCTGGCAACCACGATTTCCTGATCTGGAGTCGATCATCGCATCGGCCTGGGAATGGCACCGCACA
CATCCACACGGATATGACGACTAA

Upstream 100 bases:

>100_bases
CACCGGCAGACCACCACTCTGAACCGCCAGCCGATACAACCGCGACAGTACCTGAGTCCAATACCAATGCTGAAGCCTGA
CTGAGAGGGAGACACTCCGT

Downstream 100 bases:

>100_bases
TCCTGTTTCGGTACCCAGCCTGCCGCGTTTCTACGGTCACTACGAGGTCGAGCAGCAAATTGGGCGCGGCGAGTCGAGCC
GTGTCTTCCGCGCCCATCAC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MRILVTGGAGYIGSITSAELIRAGHEVIVIDNLYQGHRAAVPPEATFIQADLANRQELSEIFAAYPGIDGIMHFASYTLV
GESMEKPMLYLRDNVTNAGNLLEVAIAAGVRRFILSSTANLFDQPERIPIAEHERIVPGSPYGESKFFIERMLHWMARIY
GMRYACLRYFNACGDTPERGEDHDPETHLIPIVLQVALGQRPHVTIFGDDYPTRDGTCVRDYIHVLDLASAHILAMEALD
RLGERRYNLGNGQGFTVREVIETARKVTGHPIPAVVGPRRPGDPAVLVASSETIRAELGWQPRFPDLESIIASAWEWHRT
HPHGYDD

Sequences:

>Translated_327_residues
MRILVTGGAGYIGSITSAELIRAGHEVIVIDNLYQGHRAAVPPEATFIQADLANRQELSEIFAAYPGIDGIMHFASYTLV
GESMEKPMLYLRDNVTNAGNLLEVAIAAGVRRFILSSTANLFDQPERIPIAEHERIVPGSPYGESKFFIERMLHWMARIY
GMRYACLRYFNACGDTPERGEDHDPETHLIPIVLQVALGQRPHVTIFGDDYPTRDGTCVRDYIHVLDLASAHILAMEALD
RLGERRYNLGNGQGFTVREVIETARKVTGHPIPAVVGPRRPGDPAVLVASSETIRAELGWQPRFPDLESIIASAWEWHRT
HPHGYDD
>Mature_327_residues
MRILVTGGAGYIGSITSAELIRAGHEVIVIDNLYQGHRAAVPPEATFIQADLANRQELSEIFAAYPGIDGIMHFASYTLV
GESMEKPMLYLRDNVTNAGNLLEVAIAAGVRRFILSSTANLFDQPERIPIAEHERIVPGSPYGESKFFIERMLHWMARIY
GMRYACLRYFNACGDTPERGEDHDPETHLIPIVLQVALGQRPHVTIFGDDYPTRDGTCVRDYIHVLDLASAHILAMEALD
RLGERRYNLGNGQGFTVREVIETARKVTGHPIPAVVGPRRPGDPAVLVASSETIRAELGWQPRFPDLESIIASAWEWHRT
HPHGYDD

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=38.4839650145773, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=38.4839650145773, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=38.4839650145773, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI42516563, Length=323, Percent_Identity=26.625386996904, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI1786974, Length=340, Percent_Identity=39.7058823529412, Blast_Score=239, Evalue=1e-64,
Organism=Escherichia coli, GI1788353, Length=361, Percent_Identity=26.8698060941828, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994969, Length=347, Percent_Identity=26.8011527377522, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788365, Length=336, Percent_Identity=23.2142857142857, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=347, Percent_Identity=35.1585014409222, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI71982038, Length=349, Percent_Identity=34.9570200573066, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17539532, Length=268, Percent_Identity=27.6119402985075, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=38.3720930232558, Blast_Score=220, Evalue=2e-58,
Organism=Drosophila melanogaster, GI19923002, Length=345, Percent_Identity=35.6521739130435, Blast_Score=218, Evalue=5e-57,
Organism=Drosophila melanogaster, GI21356223, Length=315, Percent_Identity=25.7142857142857, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36434; Mature: 36434

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGGAGYIGSITSAELIRAGHEVIVIDNLYQGHRAAVPPEATFIQADLANRQELSE
CEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEHHHCCHHHHHH
IFAAYPGIDGIMHFASYTLVGESMEKPMLYLRDNVTNAGNLLEVAIAAGVRRFILSSTAN
HHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
LFDQPERIPIAEHERIVPGSPYGESKFFIERMLHWMARIYGMRYACLRYFNACGDTPERG
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EDHDPETHLIPIVLQVALGQRPHVTIFGDDYPTRDGTCVRDYIHVLDLASAHILAMEALD
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLGERRYNLGNGQGFTVREVIETARKVTGHPIPAVVGPRRPGDPAVLVASSETIRAELGW
HHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEHCCCC
QPRFPDLESIIASAWEWHRTHPHGYDD
CCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRILVTGGAGYIGSITSAELIRAGHEVIVIDNLYQGHRAAVPPEATFIQADLANRQELSE
CEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEHHHCCHHHHHH
IFAAYPGIDGIMHFASYTLVGESMEKPMLYLRDNVTNAGNLLEVAIAAGVRRFILSSTAN
HHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
LFDQPERIPIAEHERIVPGSPYGESKFFIERMLHWMARIYGMRYACLRYFNACGDTPERG
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EDHDPETHLIPIVLQVALGQRPHVTIFGDDYPTRDGTCVRDYIHVLDLASAHILAMEALD
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLGERRYNLGNGQGFTVREVIETARKVTGHPIPAVVGPRRPGDPAVLVASSETIRAELGW
HHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEHCCCC
QPRFPDLESIIASAWEWHRTHPHGYDD
CCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]