Click here to switch to the map view.

The map label for this gene is ddpA [H]

Identifier: 222102421

GI number: 222102421

Start: 13283

End: 14869

Strand: Direct

Name: ddpA [H]

Synonym: Avi_7015

Alternate gene names: 222102421

Gene position: 13283-14869 (Clockwise)

Preceding gene: 222102417

Following gene: 222102422

Centisome position: 2.1

GC content: 56.4

Gene sequence:

>1587_bases
ATGGGCATGATGAGCAGAATGTCATCGCGATTGTTGGGAATGACGGCTGCCGCCGCACTTTTGGGCGCTGGTATGGCTTT
TGGCGCCTCGGGCGATCTCGTCGTTAATGCGCCGACCGCACCATCCACCCTTGATCCAGCCTGGGCCTGTGGTGTTCCGG
ATATCGGGTTTCTGCAGAATTTCTATGTGCGGCTGGTCGATTTCGGCATCAAAAAGAATGCTGCGGGCAGCGAGGAAGTA
GATTACGGCGCGGTTCGGCCCTATCTGGCAAAATCTTGGACGATCAGCGATGATGGAAAGACCTATACGTTCAAGCTCAA
CGACAATTACAAGTTCACCTCCGGAAAGCCAGTCGACGCGGCTGCTGTCAAATATTCCTTCGAGCGCGGCCTCAAGATGG
GCGGCTGTGGCCAGTATTTCCTGACCGATGGGTTCCTCAGCCCGAGCATTATCGAATCGATCGAAGCGCCTGACGCGACC
ACTGTCGTCATCAAATTGATCCAGTCCAATGCCAATTCCCTCGCCGACTGGGCGACGGGAGCGGCTTCGATCGTCGATCC
GACGGTCGTTGAAGCCAATGGTGGCGTCGTTGCTGGCAAGCCGAACGAATACATGTCGTCGCATGTTGCTGGCTCCGGGC
CATATGTGCTGGATTCCTATTCGCCTAACCAGTCGGCCCATGCCACGGCCAATCCTAATTTCGGCGGCGAGCCGCCGCTG
GCGAAGTCGATCCAGATGAACTGGATTTCCTCCGCTCCGACCTTGCTGCTACAAGCCCGAAGCGGGCAAGCGGATGTCAC
CTATGGTCTCTCCAAGCAGGCGGTATCGACGCTTAAGTCTTCGCCGGATGTCAAGGTTGAGGCCTTTTCCAATCCCTTCG
TCCAGCAGATGATGTTGCCAAACACAAAGGCGCCCTGGGACAACCCGAAGGTGCGCGAGGCCGTCGCCCATGCCGTCCCT
TACGAGGATATCGTGAAGAAGGTCGCGTTCGGATACGGAACGTTCTATTTCGGCCCGGTGCCACCAAGCATGGCCGGCTT
CAATGCCGAACTGAGCAAACCAATCCAGTTTGATCTTGCCAAGGCAAAGACATTGCTGGCGGAGAGCGGTGTGAAACTGC
CGGTCGACGTCGAAGTCCTCGTTCAGGAAGGCGACACTACGCAACAGCAGATTGCCACCGTCTTGCAAAGCACCTGGTCG
AAGCTTGGCATCAACCTGAAGATCCGCATTGCGCCAGGTGCCGAATATCAGGACCTGACGCAGGGCCATAAGGTGCAGTC
GCTGATGCGGCTCGATGGTCCTGGAGTCTTCGAGGCCGGTTACTACTTCGGCTACGACGTCATGTGCAAGACGCCCTATA
ACCTGACAGAATCCTGCAATCCGAAAATCGACGAGTTGGTCGTCAAATTGCGGGCGACGTTGGACAAGGTCGAGCATCAG
AAGATCCTTGACGAGATCACCACGCTGTGGCGAGCAGACTATCCGAAGCTCCTCTTCTTCGAAGACCAGCCGGTCATTGT
CTTGAGCAACAACGTCAAGTCGTTCCGTTTCGCGCCGCTCACAGACTTCCGCTTCATGGGTAAGTAA

Upstream 100 bases:

>100_bases
ATTGACAATATGCTCTCTTAAAATACGATAGGAAATTAATTTCTGATCAGAAAAACATAAGGCCTTCCTAAAAGGGTGAC
ATAAAAAAGGGAACTGAGTA

Downstream 100 bases:

>100_bases
ATCGCCTCTAAGGCAGTTGTTGAACGCCGATATTTCCCTCTCGGCGAGCGACAGAAACAACGTCGTGTCGGGCGCACAGA
GACGAAGCCTTCTGCGGCAC

Product: ABC transporter substrate binding protein (oligopeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MGMMSRMSSRLLGMTAAAALLGAGMAFGASGDLVVNAPTAPSTLDPAWACGVPDIGFLQNFYVRLVDFGIKKNAAGSEEV
DYGAVRPYLAKSWTISDDGKTYTFKLNDNYKFTSGKPVDAAAVKYSFERGLKMGGCGQYFLTDGFLSPSIIESIEAPDAT
TVVIKLIQSNANSLADWATGAASIVDPTVVEANGGVVAGKPNEYMSSHVAGSGPYVLDSYSPNQSAHATANPNFGGEPPL
AKSIQMNWISSAPTLLLQARSGQADVTYGLSKQAVSTLKSSPDVKVEAFSNPFVQQMMLPNTKAPWDNPKVREAVAHAVP
YEDIVKKVAFGYGTFYFGPVPPSMAGFNAELSKPIQFDLAKAKTLLAESGVKLPVDVEVLVQEGDTTQQQIATVLQSTWS
KLGINLKIRIAPGAEYQDLTQGHKVQSLMRLDGPGVFEAGYYFGYDVMCKTPYNLTESCNPKIDELVVKLRATLDKVEHQ
KILDEITTLWRADYPKLLFFEDQPVIVLSNNVKSFRFAPLTDFRFMGK

Sequences:

>Translated_528_residues
MGMMSRMSSRLLGMTAAAALLGAGMAFGASGDLVVNAPTAPSTLDPAWACGVPDIGFLQNFYVRLVDFGIKKNAAGSEEV
DYGAVRPYLAKSWTISDDGKTYTFKLNDNYKFTSGKPVDAAAVKYSFERGLKMGGCGQYFLTDGFLSPSIIESIEAPDAT
TVVIKLIQSNANSLADWATGAASIVDPTVVEANGGVVAGKPNEYMSSHVAGSGPYVLDSYSPNQSAHATANPNFGGEPPL
AKSIQMNWISSAPTLLLQARSGQADVTYGLSKQAVSTLKSSPDVKVEAFSNPFVQQMMLPNTKAPWDNPKVREAVAHAVP
YEDIVKKVAFGYGTFYFGPVPPSMAGFNAELSKPIQFDLAKAKTLLAESGVKLPVDVEVLVQEGDTTQQQIATVLQSTWS
KLGINLKIRIAPGAEYQDLTQGHKVQSLMRLDGPGVFEAGYYFGYDVMCKTPYNLTESCNPKIDELVVKLRATLDKVEHQ
KILDEITTLWRADYPKLLFFEDQPVIVLSNNVKSFRFAPLTDFRFMGK
>Mature_527_residues
GMMSRMSSRLLGMTAAAALLGAGMAFGASGDLVVNAPTAPSTLDPAWACGVPDIGFLQNFYVRLVDFGIKKNAAGSEEVD
YGAVRPYLAKSWTISDDGKTYTFKLNDNYKFTSGKPVDAAAVKYSFERGLKMGGCGQYFLTDGFLSPSIIESIEAPDATT
VVIKLIQSNANSLADWATGAASIVDPTVVEANGGVVAGKPNEYMSSHVAGSGPYVLDSYSPNQSAHATANPNFGGEPPLA
KSIQMNWISSAPTLLLQARSGQADVTYGLSKQAVSTLKSSPDVKVEAFSNPFVQQMMLPNTKAPWDNPKVREAVAHAVPY
EDIVKKVAFGYGTFYFGPVPPSMAGFNAELSKPIQFDLAKAKTLLAESGVKLPVDVEVLVQEGDTTQQQIATVLQSTWSK
LGINLKIRIAPGAEYQDLTQGHKVQSLMRLDGPGVFEAGYYFGYDVMCKTPYNLTESCNPKIDELVVKLRATLDKVEHQK
ILDEITTLWRADYPKLLFFEDQPVIVLSNNVKSFRFAPLTDFRFMGK

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=499, Percent_Identity=28.8577154308617, Blast_Score=168, Evalue=7e-43,
Organism=Escherichia coli, GI1787052, Length=549, Percent_Identity=26.4116575591985, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789966, Length=546, Percent_Identity=24.5421245421245, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789887, Length=414, Percent_Identity=27.536231884058, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787551, Length=491, Percent_Identity=21.7922606924644, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789397, Length=356, Percent_Identity=24.438202247191, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081878, Length=431, Percent_Identity=26.2180974477958, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57097; Mature: 56965

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMMSRMSSRLLGMTAAAALLGAGMAFGASGDLVVNAPTAPSTLDPAWACGVPDIGFLQN
CCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEECCCCCCCCCCHHCCCCCCHHHHHH
FYVRLVDFGIKKNAAGSEEVDYGAVRPYLAKSWTISDDGKTYTFKLNDNYKFTSGKPVDA
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCEEECCCCCEEEEEECCCEEECCCCCCCH
AAVKYSFERGLKMGGCGQYFLTDGFLSPSIIESIEAPDATTVVIKLIQSNANSLADWATG
HHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCC
AASIVDPTVVEANGGVVAGKPNEYMSSHVAGSGPYVLDSYSPNQSAHATANPNFGGEPPL
CHHHCCCEEEECCCCEEECCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCC
AKSIQMNWISSAPTLLLQARSGQADVTYGLSKQAVSTLKSSPDVKVEAFSNPFVQQMMLP
CHHEEEEECCCCCEEEEEECCCCCEEEECCHHHHHHHHHCCCCEEEEECCCHHHHHHHCC
NTKAPWDNPKVREAVAHAVPYEDIVKKVAFGYGTFYFGPVPPSMAGFNAELSKPIQFDLA
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHHHHH
KAKTLLAESGVKLPVDVEVLVQEGDTTQQQIATVLQSTWSKLGINLKIRIAPGAEYQDLT
HHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHH
QGHKVQSLMRLDGPGVFEAGYYFGYDVMCKTPYNLTESCNPKIDELVVKLRATLDKVEHQ
HHHHHHHHHHCCCCCEEECCEEECEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KILDEITTLWRADYPKLLFFEDQPVIVLSNNVKSFRFAPLTDFRFMGK
HHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCEEECCCCCEEECCC
>Mature Secondary Structure 
GMMSRMSSRLLGMTAAAALLGAGMAFGASGDLVVNAPTAPSTLDPAWACGVPDIGFLQN
CHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEECCCCCCCCCCHHCCCCCCHHHHHH
FYVRLVDFGIKKNAAGSEEVDYGAVRPYLAKSWTISDDGKTYTFKLNDNYKFTSGKPVDA
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCEEECCCCCEEEEEECCCEEECCCCCCCH
AAVKYSFERGLKMGGCGQYFLTDGFLSPSIIESIEAPDATTVVIKLIQSNANSLADWATG
HHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCC
AASIVDPTVVEANGGVVAGKPNEYMSSHVAGSGPYVLDSYSPNQSAHATANPNFGGEPPL
CHHHCCCEEEECCCCEEECCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCC
AKSIQMNWISSAPTLLLQARSGQADVTYGLSKQAVSTLKSSPDVKVEAFSNPFVQQMMLP
CHHEEEEECCCCCEEEEEECCCCCEEEECCHHHHHHHHHCCCCEEEEECCCHHHHHHHCC
NTKAPWDNPKVREAVAHAVPYEDIVKKVAFGYGTFYFGPVPPSMAGFNAELSKPIQFDLA
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHHHHH
KAKTLLAESGVKLPVDVEVLVQEGDTTQQQIATVLQSTWSKLGINLKIRIAPGAEYQDLT
HHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHH
QGHKVQSLMRLDGPGVFEAGYYFGYDVMCKTPYNLTESCNPKIDELVVKLRATLDKVEHQ
HHHHHHHHHHCCCCCEEECCEEECEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KILDEITTLWRADYPKLLFFEDQPVIVLSNNVKSFRFAPLTDFRFMGK
HHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]