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The map label for this gene is phoR [H]

Identifier: 222095192

GI number: 222095192

Start: 1506335

End: 1508146

Strand: Reverse

Name: phoR [H]

Synonym: BCQ_1532

Alternate gene names: 222095192

Gene position: 1508146-1506335 (Counterclockwise)

Preceding gene: 222095193

Following gene: 222095191

Centisome position: 28.92

GC content: 31.95

Gene sequence:

>1812_bases
GTGAAAAACAGAAGTATCGTCTTTAAACTATTCTTATTAACATCGACATTATTTACAATCATATTCCTCCTATTTTTCCT
AGGACAATCTCTATTTTTAGAGAAATTTTATATTAATAAAAAAGTAAAAACAGTTCAAACTGCTTTTGAGGATTTCGTAG
ATACGTACGAAAAAAGTGGGAAAAGTTATGAAGAAATTCGAAAACTAAAACAAGAATTTCATGATAAAACAAATGCTGAT
ATGCAATTTCTATCTCCTGAAGGCATTATTAAAAGTGACAACAATTACTATATTGATGTAATTAATCCTAAAAATAGTGA
AGCATATTCCATTCCGCTCAATAATCTTTTAACGCCCGAAGAATATAAAAAATTTGAAAACTTAGGATTGAAAAAAGATG
ACATGATCAACGTCGTCGGTTGGGTACGAGGGAAAATAATAACACCACTAGAATTGACAACAAGTTATAATCGATGGCAA
AACGAACGTATCAATTCAGATTTTTCATCCATTAATGGCAATCCTTCTAAAAATAGAATTACAAGCCGATACAAACCTGT
GACTCAAATTGAGTTTACTGGTATTGTTTCTAAGTTACAGCTTCCATCCAAAGCGGATGTTCGTCTTGCAAATGATTTTG
AAACATTACAAGCCGTTCAATATTTTGCAGATATTATTAGAAATGGTACTGCTAACTCGCATCAATTAAGCTATTTTCTA
CTAGATAGTGAAGAGAATATAAAAAATAGCATCTTTGTAAAGCCTATTATGGAAAATGGAAAGATTACAGAATATGCTTT
TGCGATAGCATCCTTGCAACCTGTTAATGAAGCGATGCTCGTTTTGAAAGATTATTATGTCTATGCCTTAATCATCGTAT
TTCTCGTAATTATTTTGTTATCCTTCTACTACTCAAAAATTATTGTGAAACCATTAATTAAAATGAATCGTGTTACAAAA
AAAATGGCCAATTTTGATTTTAGCGAGAAATTACCTGTAACAGCAGACGATGAAATTGGAGGGCTTTCCGGTAGTATTAA
TACGTTATCTGTAAATTTAAAAGACCGAATTGATCGATTAAATGTTGCCAATACAAAATTACAACAAGATATTGAACGTG
AACGTCAATTAGAGAAAACGCGAAAAGAATTCATTTCTGGTGTATCACACGAATTAAAAACACCACTTAGTGTAATTAGA
AGTTTCGCAGAAGGAATTAAAGATGGCGTTAGTAAAGATACGACGTATTACACAGATGTTATTTTAGAAGAAACCGAAAA
CATGAACAGACTTATTGTTGAAATGTTAGAATTAGCAAAATTAGAATCAGGTACGTACAAGCTAGATATGACGACATTCT
CAATCGGTGAACTAATTCAACAAGTCTATACAAAGTTATTATTTAGCATGGAGGAAAAACATTTACAAGTGAATATAGAT
GTAGACCCTTCTATATTTGTGAAAGCGAATCGTAGTCGAATTGAACAAGTAGTTGTGAACTTACTTAGCAATGCAATTCG
CTATACGCCAGATGGAGAAAAAATACAAGTCTCCGTTATAGAAATGGAAGATACAGTAAAAGTTGAAATCGAAAACACAG
GAAACCCTATTCCAGAAGACAGTCTTGAAAAAATTTGGGATCGTTTCTACCGTTTAGATGCATCGCGTAGCCGTCATACT
GGTGGTACTGGTCTTGGATTATCTATTGTTAAAAATATTTTAGACCTCCACCATGCCGAGTATGGTGTATATAATACGAC
TAATAGTGTTGTATTCTACTTTAATTTACAAAAAGTAAAAGAAGTCAAATAA

Upstream 100 bases:

>100_bases
AAAACTACTTTCAGAAGAGACAGATTTTCTCCTCTACTTTTTTGTAACGTTTGTTATAATTAAGAAATCATTTACAGTAT
TTCTCACAAGAGGTGACGCA

Downstream 100 bases:

>100_bases
TTTGTCTTAATTTCACTAGGAGTTCACATGAAATTCACACTCTCCCTTTATAGTTAGAAACAAGTTAATCCTTTCCTTTA
CACATATAAAAGAGGAGAGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEDFVDTYEKSGKSYEEIRKLKQEFHDKTNAD
MQFLSPEGIIKSDNNYYIDVINPKNSEAYSIPLNNLLTPEEYKKFENLGLKKDDMINVVGWVRGKIITPLELTTSYNRWQ
NERINSDFSSINGNPSKNRITSRYKPVTQIEFTGIVSKLQLPSKADVRLANDFETLQAVQYFADIIRNGTANSHQLSYFL
LDSEENIKNSIFVKPIMENGKITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKMNRVTK
KMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIR
SFAEGIKDGVSKDTTYYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
VDPSIFVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSVIEMEDTVKVEIENTGNPIPEDSLEKIWDRFYRLDASRSRHT
GGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVKEVK

Sequences:

>Translated_603_residues
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEDFVDTYEKSGKSYEEIRKLKQEFHDKTNAD
MQFLSPEGIIKSDNNYYIDVINPKNSEAYSIPLNNLLTPEEYKKFENLGLKKDDMINVVGWVRGKIITPLELTTSYNRWQ
NERINSDFSSINGNPSKNRITSRYKPVTQIEFTGIVSKLQLPSKADVRLANDFETLQAVQYFADIIRNGTANSHQLSYFL
LDSEENIKNSIFVKPIMENGKITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKMNRVTK
KMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIR
SFAEGIKDGVSKDTTYYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
VDPSIFVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSVIEMEDTVKVEIENTGNPIPEDSLEKIWDRFYRLDASRSRHT
GGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVKEVK
>Mature_603_residues
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEDFVDTYEKSGKSYEEIRKLKQEFHDKTNAD
MQFLSPEGIIKSDNNYYIDVINPKNSEAYSIPLNNLLTPEEYKKFENLGLKKDDMINVVGWVRGKIITPLELTTSYNRWQ
NERINSDFSSINGNPSKNRITSRYKPVTQIEFTGIVSKLQLPSKADVRLANDFETLQAVQYFADIIRNGTANSHQLSYFL
LDSEENIKNSIFVKPIMENGKITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKMNRVTK
KMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIR
SFAEGIKDGVSKDTTYYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
VDPSIFVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSVIEMEDTVKVEIENTGNPIPEDSLEKIWDRFYRLDASRSRHT
GGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVKEVK

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=298, Percent_Identity=27.8523489932886, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=28.8288288288288, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1789149, Length=344, Percent_Identity=23.8372093023256, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786783, Length=314, Percent_Identity=27.0700636942675, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788279, Length=327, Percent_Identity=27.5229357798165, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790861, Length=232, Percent_Identity=30.1724137931034, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082128, Length=325, Percent_Identity=21.8461538461538, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=27.3542600896861, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=23.9837398373984, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788713, Length=215, Percent_Identity=27.4418604651163, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790551, Length=308, Percent_Identity=25.3246753246753, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787894, Length=216, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=28.6363636363636, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=25.5060728744939, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=315, Percent_Identity=23.4920634920635, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1790346, Length=204, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI48994928, Length=214, Percent_Identity=25.2336448598131, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790300, Length=278, Percent_Identity=27.3381294964029, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787374, Length=333, Percent_Identity=20.4204204204204, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1789808, Length=297, Percent_Identity=24.2424242424242, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789403, Length=222, Percent_Identity=25.2252252252252, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69331; Mature: 69331

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEDFVDTYEKSG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSYEEIRKLKQEFHDKTNADMQFLSPEGIIKSDNNYYIDVINPKNSEAYSIPLNNLLTPE
CCHHHHHHHHHHHCCCCCCCEEEECCCCCEECCCCEEEEEECCCCCCEEECCHHHCCCHH
EYKKFENLGLKKDDMINVVGWVRGKIITPLELTTSYNRWQNERINSDFSSINGNPSKNRI
HHHHHHHCCCCCCHHHHHHHHHCCCEECCEEECCCHHHHHHHHCCCCHHHCCCCCCHHHH
TSRYKPVTQIEFTGIVSKLQLPSKADVRLANDFETLQAVQYFADIIRNGTANSHQLSYFL
HHHCCCCCEEEHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
LDSEENIKNSIFVKPIMENGKITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILL
ECCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SFYYSKIIVKPLIKMNRVTKKMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHC
NVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIRSFAEGIKDGVSKDTTYYTDV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
HHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
VDPSIFVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSVIEMEDTVKVEIENTGNPIPED
CCCCEEEECCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCEEEEEECCCCCCCCHH
SLEKIWDRFYRLDASRSRHTGGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVK
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEHHHHH
EVK
CCC
>Mature Secondary Structure
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEDFVDTYEKSG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSYEEIRKLKQEFHDKTNADMQFLSPEGIIKSDNNYYIDVINPKNSEAYSIPLNNLLTPE
CCHHHHHHHHHHHCCCCCCCEEEECCCCCEECCCCEEEEEECCCCCCEEECCHHHCCCHH
EYKKFENLGLKKDDMINVVGWVRGKIITPLELTTSYNRWQNERINSDFSSINGNPSKNRI
HHHHHHHCCCCCCHHHHHHHHHCCCEECCEEECCCHHHHHHHHCCCCHHHCCCCCCHHHH
TSRYKPVTQIEFTGIVSKLQLPSKADVRLANDFETLQAVQYFADIIRNGTANSHQLSYFL
HHHCCCCCEEEHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
LDSEENIKNSIFVKPIMENGKITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILL
ECCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SFYYSKIIVKPLIKMNRVTKKMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHC
NVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIRSFAEGIKDGVSKDTTYYTDV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
HHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
VDPSIFVKANRSRIEQVVVNLLSNAIRYTPDGEKIQVSVIEMEDTVKVEIENTGNPIPED
CCCCEEEECCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCEEEEEECCCCCCCCHH
SLEKIWDRFYRLDASRSRHTGGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVK
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEHHHHH
EVK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]