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The map label for this gene is gltT [H]

Identifier: 222095122

GI number: 222095122

Start: 1437514

End: 1438749

Strand: Reverse

Name: gltT [H]

Synonym: BCQ_1462

Alternate gene names: 222095122

Gene position: 1438749-1437514 (Counterclockwise)

Preceding gene: 222095124

Following gene: 222095119

Centisome position: 27.59

GC content: 37.94

Gene sequence:

>1236_bases
TTGAAACAAACAAAAGCAATCTTAATTGCATTATTTCTCGGTTTAGTTGTCGGACTCACTTTAAATTTAGCTGCACCATC
CATTTTTGAACCATTAAATCAATATGTGTTCAATCCACTTGGTCAATTGTTTATTCGCCTCATTAAAATGCTAGTTGTCC
CTGTTGTATTCATTTCTATCGTACTTGGAGCTGCTGGTCTTGGAGATCCGAAGCAACTTGGAAGAATTGGTTTAAAATCA
ATTTCATTCTTTCTTGTAACTACAGCCGTTGCCATCTCTATTGCAGTTACATTTGCACTGATTATACAACCAGGATCTGG
TGGTAATTTTAAAACCGAAGGGCTTAAATATGAAGGTGCAAAAACCGAAACATCTTTCGTCGATACATTGCTAAATATCG
TACCAGATAATCCAGCAAAAGCGATGGCTGATGGAAACATGTTACAAATTATTGCCTTTGCCGTATTAATTGGACTTGGT
ATAGCTATTTTAGGAAAACGTGTCCAAGGTATTCATTCATTACTTGAACAGGGCAACGAATTAATGATGTATCTCGTTAA
TCTCGTTATGAAATTAGCTCCAATCGGAACATTTGGGTTGCTTGCTTCATCCGTCGGTAAAATGGGTCTTGCAGGCGTCG
CTGCGATGTTCAAGTATATGATTGTCGTTATGCTAGTACTTATTATTCACGGTGTCTTCGTATATGGTGGCTTATTAAAA
GTATTGGCAAAAGAAAGCATTGTCCGTTTCTTTAAACATTTCGGACCAGTAATGGCGATTGGATTTAGTACATCTAGCTC
TAATGCATCTCTTCCATTTGCAATGAAAACCGCACAAGAGAAGCTTGGTGTTCCAAAAGCAATTAGCTCTTTTGTACAAC
CACTAGGTGCAACAATTAATATGGATGGTACTGCCATTATGCAAGGTGTAGCAACTGTATTTATCGCTCAAGTATACGGC
GTTGAACTTACTATTTCCCAACTAGCTGTAGTCGTATTAACTGCTGTACTAGCTAGTATCGGCACTGCTGGTGTACCAGG
TGTTGGGCTTGTAATGCTGACGATGGTTTTAAATCAAGTAAATCTACCAGTAGAAGGTATTGCCTTAATTATCGGTATTG
ACCGCATTCTAGATATGTCAAGAACAGCTGTAAATATTTCTGGTGATGCAATTTGCGCAATGATTGTCGCAAAATCAGAA
GAAAAATATAATACAGATCAATCTGCCGCATCTTAA

Upstream 100 bases:

>100_bases
ACTTTTTGTACTAAATATTCAGAAAATATTGTCAAAATAGGTAGTTTTTCGGTACAATTAATGTAGAAAGCTATTTTACA
AAAAATAAGGGGGGATTTTA

Downstream 100 bases:

>100_bases
ATCAAAAAAGGAGTGAAATGATTCACTCCTTTTTTGATTTACTTCCCTTTTTCGAACGATATTCTTTTCCTTTATTATCG
TTACCAGTTTCAAATTCTGC

Product: proton/glutamate symporter family protein

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MKQTKAILIALFLGLVVGLTLNLAAPSIFEPLNQYVFNPLGQLFIRLIKMLVVPVVFISIVLGAAGLGDPKQLGRIGLKS
ISFFLVTTAVAISIAVTFALIIQPGSGGNFKTEGLKYEGAKTETSFVDTLLNIVPDNPAKAMADGNMLQIIAFAVLIGLG
IAILGKRVQGIHSLLEQGNELMMYLVNLVMKLAPIGTFGLLASSVGKMGLAGVAAMFKYMIVVMLVLIIHGVFVYGGLLK
VLAKESIVRFFKHFGPVMAIGFSTSSSNASLPFAMKTAQEKLGVPKAISSFVQPLGATINMDGTAIMQGVATVFIAQVYG
VELTISQLAVVVLTAVLASIGTAGVPGVGLVMLTMVLNQVNLPVEGIALIIGIDRILDMSRTAVNISGDAICAMIVAKSE
EKYNTDQSAAS

Sequences:

>Translated_411_residues
MKQTKAILIALFLGLVVGLTLNLAAPSIFEPLNQYVFNPLGQLFIRLIKMLVVPVVFISIVLGAAGLGDPKQLGRIGLKS
ISFFLVTTAVAISIAVTFALIIQPGSGGNFKTEGLKYEGAKTETSFVDTLLNIVPDNPAKAMADGNMLQIIAFAVLIGLG
IAILGKRVQGIHSLLEQGNELMMYLVNLVMKLAPIGTFGLLASSVGKMGLAGVAAMFKYMIVVMLVLIIHGVFVYGGLLK
VLAKESIVRFFKHFGPVMAIGFSTSSSNASLPFAMKTAQEKLGVPKAISSFVQPLGATINMDGTAIMQGVATVFIAQVYG
VELTISQLAVVVLTAVLASIGTAGVPGVGLVMLTMVLNQVNLPVEGIALIIGIDRILDMSRTAVNISGDAICAMIVAKSE
EKYNTDQSAAS
>Mature_411_residues
MKQTKAILIALFLGLVVGLTLNLAAPSIFEPLNQYVFNPLGQLFIRLIKMLVVPVVFISIVLGAAGLGDPKQLGRIGLKS
ISFFLVTTAVAISIAVTFALIIQPGSGGNFKTEGLKYEGAKTETSFVDTLLNIVPDNPAKAMADGNMLQIIAFAVLIGLG
IAILGKRVQGIHSLLEQGNELMMYLVNLVMKLAPIGTFGLLASSVGKMGLAGVAAMFKYMIVVMLVLIIHGVFVYGGLLK
VLAKESIVRFFKHFGPVMAIGFSTSSSNASLPFAMKTAQEKLGVPKAISSFVQPLGATINMDGTAIMQGVATVFIAQVYG
VELTISQLAVVVLTAVLASIGTAGVPGVGLVMLTMVLNQVNLPVEGIALIIGIDRILDMSRTAVNISGDAICAMIVAKSE
EKYNTDQSAAS

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI21314632, Length=403, Percent_Identity=33.2506203473945, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI169790839, Length=455, Percent_Identity=31.4285714285714, Blast_Score=185, Evalue=8e-47,
Organism=Homo sapiens, GI5032093, Length=399, Percent_Identity=34.5864661654135, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI40254478, Length=448, Percent_Identity=31.0267857142857, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI66773030, Length=450, Percent_Identity=30, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI223468564, Length=250, Percent_Identity=37.2, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI223468566, Length=250, Percent_Identity=37.2, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI4827012, Length=286, Percent_Identity=34.965034965035, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI194239697, Length=264, Percent_Identity=36.7424242424242, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI262359914, Length=377, Percent_Identity=28.3819628647215, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI301601644, Length=172, Percent_Identity=40.6976744186046, Blast_Score=125, Evalue=9e-29,
Organism=Escherichia coli, GI1790514, Length=416, Percent_Identity=37.2596153846154, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1789947, Length=410, Percent_Identity=31.9512195121951, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1788024, Length=394, Percent_Identity=28.4263959390863, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789473, Length=286, Percent_Identity=27.6223776223776, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71983106, Length=415, Percent_Identity=32.7710843373494, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71983099, Length=415, Percent_Identity=32.7710843373494, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71996953, Length=464, Percent_Identity=30.3879310344828, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17537407, Length=433, Percent_Identity=32.1016166281755, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI193206505, Length=445, Percent_Identity=29.2134831460674, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI193206654, Length=396, Percent_Identity=30.3030303030303, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17541374, Length=398, Percent_Identity=27.1356783919598, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24583025, Length=429, Percent_Identity=28.9044289044289, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17137668, Length=429, Percent_Identity=28.9044289044289, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24583023, Length=429, Percent_Identity=28.9044289044289, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281360481, Length=455, Percent_Identity=27.4725274725275, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281360483, Length=455, Percent_Identity=27.9120879120879, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI17137666, Length=455, Percent_Identity=27.9120879120879, Blast_Score=125, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 43131; Mature: 43131

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCHHCCCCCCCCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]