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The map label for this gene is uvrD [H]

Identifier: 222094777

GI number: 222094777

Start: 1101280

End: 1103616

Strand: Reverse

Name: uvrD [H]

Synonym: BCQ_1115

Alternate gene names: 222094777

Gene position: 1103616-1101280 (Counterclockwise)

Preceding gene: 222094778

Following gene: 222094775

Centisome position: 21.17

GC content: 39.62

Gene sequence:

>2337_bases
ATGAACAAAAAACTTGATTTAGAGCAAAAACGATTGGATACCGTAATCGAAACGATTACGCAACAAATTGATAAACTGGA
AAACGAAACTGGCAGACGCCGGGCAGAAGTAATCCATATTCGTAAACACTTTTGGGATGACGTGAAAGTGAATACTGATA
CTTTTGATGATTATCTTGAAACAGTTATCAACTTAAGACAACAAGCTCAGTCACTAGCTGTCACACAAATTACCCATAAG
CACACCTTTAATCGACTTGCCGCACTAAAACGCATGCATAAAGCACCTTATTTCGGACGAATTGATTTCAAAGAAGAAGG
AGAATCTGCTGCAGAGCAAATTTATATTGGCGTTGCTACACTTACTGATGCTAGCGGAGAAAACTTTCTTATATACGACT
GGCGCGCCCCCATTTCAAGTGTGTACTACGATTATCCACCAGGACCGGCTCAATATAGTACACCAGGCGGCGTAATCCAC
GGTAATGTGGAGAAAAAATTACAATACATTATTGAAAATGGCGAGATTGATTCTATGTTCGATACGAGCCTTACAATTGG
CGATGAAATCTTGCAACAAGCGCTCGGAAAAGGTACAAACAAACATATGCAAAGTATCGTCGCTACAATTCAGCGCGAAC
AAAATGAAATTATTCGTCACGATGAAGGCCGACTCCTTATCGTGCAAGGAGCTGCTGGTAGTGGTAAAACGTCAGCTGCC
CTGCAACGAATCGCCTACTTACTATATAAATATCGCGAATGGCTAAAAGCAGATCAAATTATTCTCTTCTCCCCTAACTC
TATGTTCAATAGCTACGTATCTAACGTACTACCTGAACTCGGCGAAGAAAATATGCAGCAAGTGACATTCCAAGAATATT
TAAATCATAGACTAAGTAAGTCATTTGACGTGGAAGATCCATACGAGCAATTAGAATATATGCTCACTGAAACAAATAGC
CCTATCTATAAAACAAGAAATGCAAGCATTCGCTTTAAAGCATCTACTCAATTTTTCGAAATGATTCGAGCGTACAGACA
ATCTCTTGAATCATCAGGCATGCTATTTAGAGGAATGAAATTTAGAGGAAAGCTAATTGTCTCTGCGAAAGAAATTACAG
AGCAATTTTATAATACTGACTCCTCTCTCCGCTTCCATAGCCGAATTGAGAAGTTAACGGATTGGCTAAATAAGCAAATA
GATGCACTTGAAAAAGCAGAACTGAAAAAGCCTTGGGTAGAAGAAGAAATCGAACTACTTAGTAAAGATGAATATCAAAA
GGCTTATAAATATTTACAGAAAAAGGGCGAGTTTGACGACAACTCCTTTAACGATTTTGAGAAAGAGGCGAAAGTACTTG
GACGTATGATTGTCCGTAAAAAATTGAAGCCACTTCGTAAAGGTGTTCAAACATTGCGCTTTATCAATTTCACAGGCATA
TATAAACAGCTATTCACAGATGCATCATGGGTTACGGGAGAAAAACCGAAAAACTGGGATGACATTTGTTCATTAACGGT
GAACATGTTAGATGAAGGAAAGCTATATTACGAGGATGCGACTCCATTTTTACTTTTAAAAGAGTTAATTGAAGGCTTCC
AAACAAATAGATCGATTAAGCACGTACTCGTAGACGAAGCGCAAGATTATTCACCATTTCAGTTCGAGTTTTTAAAACGT
CTCTTCCCTGCTGCAAGAATGACGGTACTCGGAGACTTTAACCAAGCAATATTTGCTCATGCGAGTGAAACGGTGAATTT
CGATACACTTACAAATTTATACGGGCCGGATGAAACGAACGGCATTAACTTAACTCGTAGCTACCGCTCAACAAAACCGA
TTATTGAATTTACACGGGCTCTCGTACCGGAAGGAAAGAACATCCATGCATTTGAACGTGATGGTGAGAAACCTACAGTG
ACGAAAGTAGCGAATGAGAGCGTACTGCACGAACGTATTACTGCCAAAGTTGCTGAACTACAAACAGAGCAGCACAATAC
GATCGCAATTATATGTAAATCTGCAGCTGAAAGCGCCGCGGCCTATGAGGCACTTATTCATATCGAGAATATTAAACTCG
TGAAGAGTAACTCAGCTGAGTATGAGCAAGGCATCGTCGTGATCCCAGCTTACTTAGCGAAAGGTATCGAATTTGATGCT
GTTATTATTTACAATGCTTCTAAAGATGTATACAGCGATGAGAGCGTTCGTAGATTATTCTACACTGCTTGTACGCGTGC
AATGCATGAATTACAACTTTATAGCGTTGGCGAGGTTAGTCCTTTTATACTTGGGGCTGATTCGGAGAGTTTTGAGCTTA
TAACGAAAACACCTTGA

Upstream 100 bases:

>100_bases
TTACAAATTAACTAAAACATATTTATCCGTATATCAAATATACCATAGTTTCTTTCTTCAGTCAACCTCTATTTTTCACT
TTTAAAGGAGTGCTTACCGT

Downstream 100 bases:

>100_bases
TGATTCAAGGTGTTTCTTTTTTATGCAGGTGCAGGAGGATGCAGCCATACAGCGGCGGAAGATTCAGCTTACTCCTAAAA
ATCTTCTACCCTATTCCCCT

Product: ATP-dependent DNA helicase replicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 778; Mature: 778

Protein sequence:

>778_residues
MNKKLDLEQKRLDTVIETITQQIDKLENETGRRRAEVIHIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALKRMHKAPYFGRIDFKEEGESAAEQIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAQYSTPGGVIH
GNVEKKLQYIIENGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PIYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDSSLRFHSRIEKLTDWLNKQI
DALEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFNDFEKEAKVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWVTGEKPKNWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV
TKVANESVLHERITAKVAELQTEQHNTIAIICKSAAESAAAYEALIHIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
VIIYNASKDVYSDESVRRLFYTACTRAMHELQLYSVGEVSPFILGADSESFELITKTP

Sequences:

>Translated_778_residues
MNKKLDLEQKRLDTVIETITQQIDKLENETGRRRAEVIHIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALKRMHKAPYFGRIDFKEEGESAAEQIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAQYSTPGGVIH
GNVEKKLQYIIENGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PIYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDSSLRFHSRIEKLTDWLNKQI
DALEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFNDFEKEAKVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWVTGEKPKNWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV
TKVANESVLHERITAKVAELQTEQHNTIAIICKSAAESAAAYEALIHIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
VIIYNASKDVYSDESVRRLFYTACTRAMHELQLYSVGEVSPFILGADSESFELITKTP
>Mature_778_residues
MNKKLDLEQKRLDTVIETITQQIDKLENETGRRRAEVIHIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALKRMHKAPYFGRIDFKEEGESAAEQIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAQYSTPGGVIH
GNVEKKLQYIIENGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PIYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDSSLRFHSRIEKLTDWLNKQI
DALEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFNDFEKEAKVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWVTGEKPKNWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV
TKVANESVLHERITAKVAELQTEQHNTIAIICKSAAESAAAYEALIHIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
VIIYNASKDVYSDESVRRLFYTACTRAMHELQLYSVGEVSPFILGADSESFELITKTP

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 89391; Mature: 89391

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLDLEQKRLDTVIETITQQIDKLENETGRRRAEVIHIRKHFWDDVKVNTDTFDDYLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEECCCHHHHHHH
TVINLRQQAQSLAVTQITHKHTFNRLAALKRMHKAPYFGRIDFKEEGESAAEQIYIGVAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHEEEEEEE
LTDASGENFLIYDWRAPISSVYYDYPPGPAQYSTPGGVIHGNVEKKLQYIIENGEIDSMF
EECCCCCEEEEEECCCCHHHCEECCCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCHH
DTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSK
HHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
SFDVEDPYEQLEYMLTETNSPIYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMK
CCCCCCHHHHHHHHHHCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHHHCCCEEECCC
FRGKLIVSAKEITEQFYNTDSSLRFHSRIEKLTDWLNKQIDALEKAELKKPWVEEEIELL
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SKDEYQKAYKYLQKKGEFDDNSFNDFEKEAKVLGRMIVRKKLKPLRKGVQTLRFINFTGI
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKQLFTDASWVTGEKPKNWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIK
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHH
HVLVDEAQDYSPFQFEFLKRLFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETN
HHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHCCCCCCHHHHHHCCCCCCCC
GINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTVTKVANESVLHERITAKVAEL
CCEEEECCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QTEQHNTIAIICKSAAESAAAYEALIHIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
HHCCCCEEEEEEEHHHHHHHHHHHHHEEEEEEEEECCCCHHHCCEEEEEHHHHCCCCCCE
VIIYNASKDVYSDESVRRLFYTACTRAMHELQLYSVGEVSPFILGADSESFELITKTP
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCCEEEECCC
>Mature Secondary Structure
MNKKLDLEQKRLDTVIETITQQIDKLENETGRRRAEVIHIRKHFWDDVKVNTDTFDDYLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEECCCHHHHHHH
TVINLRQQAQSLAVTQITHKHTFNRLAALKRMHKAPYFGRIDFKEEGESAAEQIYIGVAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHEEEEEEE
LTDASGENFLIYDWRAPISSVYYDYPPGPAQYSTPGGVIHGNVEKKLQYIIENGEIDSMF
EECCCCCEEEEEECCCCHHHCEECCCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCHH
DTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSK
HHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
SFDVEDPYEQLEYMLTETNSPIYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMK
CCCCCCHHHHHHHHHHCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHHHCCCEEECCC
FRGKLIVSAKEITEQFYNTDSSLRFHSRIEKLTDWLNKQIDALEKAELKKPWVEEEIELL
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SKDEYQKAYKYLQKKGEFDDNSFNDFEKEAKVLGRMIVRKKLKPLRKGVQTLRFINFTGI
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKQLFTDASWVTGEKPKNWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIK
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHH
HVLVDEAQDYSPFQFEFLKRLFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETN
HHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHCCCCCCHHHHHHCCCCCCCC
GINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTVTKVANESVLHERITAKVAEL
CCEEEECCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QTEQHNTIAIICKSAAESAAAYEALIHIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
HHCCCCEEEEEEEHHHHHHHHHHHHHEEEEEEEEECCCCHHHCCEEEEEHHHHCCCCCCE
VIIYNASKDVYSDESVRRLFYTACTRAMHELQLYSVGEVSPFILGADSESFELITKTP
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]